7OGB

GTPase HRAS under 500 MPa pressure

Summary for 7OGB

Entry DOI	10.2210/pdb7ogb/pdb
Related	7OG9 7OGA 7OGC 7OGD 7OGE 7OGF
Descriptor	GTPase HRas, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	g protein, signaling protein, oncogene protein, oncoprotein, hpmx
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	19960.32
Authors	Colloc'h, N.C.,Girard, E.,Prange, T.,Kalbitzer, H.R. (deposition date: 2021-05-06, release date: 2022-02-09, Last modification date: 2024-01-31)
Primary citation	Girard, E.,Lopes, P.,Spoerner, M.,Dhaussy, A.C.,Prange, T.,Kalbitzer, H.R.,Colloc'h, N. Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. Chem Sci, 13:2001-2010, 2022 Cited by PubMed: 35308861 DOI: 10.1039/d1sc05488k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation