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2D9Q
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Crystal Structure of the Human GCSF-Receptor Signaling Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CSF3, Granulocyte colony-stimulating factor receptor
著者Tamada, T, Kuroki, R.
登録日2005-12-12
公開日2006-02-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Homodimeric cross-over structure of the human granulocyte colony-stimulating factor (GCSF) receptor signaling complex
Proc.Natl.Acad.Sci.Usa, 103, 2006
2DA3
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Solution structure of the third homeobox domain of AT-binding transcription factor 1 (ATBF1)
分子名称: Alpha-fetoprotein enhancer binding protein
著者Ohnishi, S, Kigawa, T, Tomizawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-13
公開日2006-06-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the third homeobox domain of AT-binding transcription factor 1 (ATBF1)
To be Published
2DMS
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Solution structure of the homeobox domain of Homeobox protein OTX2
分子名称: Homeobox protein OTX2
著者Ohnishi, S, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-04-24
公開日2006-10-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the homeobox domain of Homeobox protein OTX2
To be Published
2DS1
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Human cyclin dependent kinase 2 complexed with the CDK4 inhibitor
分子名称: (13R,15S)-13-METHYL-16-OXA-8,9,12,22,24-PENTAAZAHEXACYCLO[15.6.2.16,9.1,12,15.0,2,7.0,21,25]HEPTACOSA-1(24),2,4,6,17(25 ),18,20-HEPTAENE-23,26-DIONE, Cell division protein kinase 2
著者Ikuta, M.
登録日2006-06-17
公開日2007-06-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-based drug design of a highly potent CDK1,2,4,6 inhibitor with novel macrocyclic quinoxalin-2-one structure
Bioorg.Med.Chem.Lett., 16, 2006
1VK5
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X-ray Structure of Gene Product from Arabidopsis Thaliana At3g22680
分子名称: 1,2-ETHANEDIOL, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, SULFATE ION, ...
著者Wesenberg, G.E, Smith, D.W, Phillips Jr, G.N, Johnson, K.A, Bingman, C.A, Allard, S.T.M, Center for Eukaryotic Structural Genomics (CESG)
登録日2004-05-06
公開日2004-05-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.604 Å)
主引用文献Structure at 1.6 A resolution of the protein from gene locus At3g22680 from Arabidopsis thaliana.
Acta Crystallogr.,Sect.F, 61, 2005
2F21
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human Pin1 Fip mutant
分子名称: PENTAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Jager, M, Zhang, Y, Bowman, M.E, Noel, J.P, Kelly, J.W.
登録日2005-11-15
公開日2006-06-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-function-folding relationship in a WW domain.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2F6J
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Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4me3 bound state
分子名称: ZINC ION, bromodomain PHD finger transcription factor, histone H3, ...
著者Li, H, Patel, D.J.
登録日2005-11-29
公開日2006-07-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
2E32
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Structural basis for selection of glycosylated substrate by SCFFbs1 ubiquitin ligase
分子名称: F-box only protein 2, S-phase kinase-associated protein 1A
著者Mizushima, T, Yoshida, Y, Kumanomidou, T, Hasegawa, Y, Yamane, T, Tanaka, K.
登録日2006-11-20
公開日2007-03-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.52 Å)
主引用文献Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E5C
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Crystal structure of Human NMPRTase complexed with 5'-phosphoribosyl-1'-pyrophosphate
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Nicotinamide phosphoribosyltransferase
著者Takahashi, R, Nakamura, S, Kobayashi, Y, Ohkubo, T.
登録日2006-12-20
公開日2007-12-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase
J.Biochem., 147, 2010
2E6Z
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Solution structure of the second KOW motif of human transcription elongation factor SPT5
分子名称: Transcription elongation factor SPT5
著者Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-01-05
公開日2007-07-10
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the second KOW motif of human transcription elongation factor SPT5
To be Published
2FUH
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Solution Structure of the UbcH5c/Ub Non-covalent Complex
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 D3
著者Brzovic, P.S, Lissounov, A, Hoyt, D.W, Klevit, R.E.
登録日2006-01-26
公開日2006-03-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A UbcH5/Ubiquitin Noncovalent Complex Is Required for Processive BRCA1-Directed Ubiquitination.
Mol.Cell, 21, 2006
2FUI
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NMR solution structure of PHD finger fragment of human BPTF in free state
分子名称: bromodomain PHD finger transcription factor
著者Ilin, S, Patel, D.J.
登録日2006-01-26
公開日2006-07-11
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
7Y1J
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Structure of SUR2A in complex with Mg-ATP and repaglinide in the inward-facing conformation.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 9, MAGNESIUM ION, ...
著者Chen, L, Ding, D, Hou, T.
登録日2022-06-08
公開日2023-06-14
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix.
Nat Commun, 14, 2023
7Y1L
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Structure of SUR2B in complex with Mg-ATP and repaglinide in the inward-facing conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Isoform SUR2B of ATP-binding cassette sub-family C member 9, MAGNESIUM ION, ...
著者Chen, L, Ding, D, Hou, T.
登録日2022-06-08
公開日2023-06-14
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix.
Nat Commun, 14, 2023
7Y1K
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Structure of SUR2A in complex with Mg-ATP, Mg-ADP and repaglinide in the inward-facing conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 9, ...
著者Chen, L, Ding, D, Hou, T.
登録日2022-06-08
公開日2023-06-14
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix.
Nat Commun, 14, 2023
7Y1M
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Structure of SUR2B in complex with Mg-ATP, Mg-ADP, and repaglinide in the inward-facing conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Isoform SUR2B of ATP-binding cassette sub-family C member 9, ...
著者Chen, L, Ding, D, Hou, T.
登録日2022-06-08
公開日2023-06-14
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix.
Nat Commun, 14, 2023
7Y1N
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Structure of SUR2B in complex with Mg-ATP, Mg-ADP, and repaglinide in the partially occluded state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Isoform SUR2B of ATP-binding cassette sub-family C member 9, ...
著者Chen, L, Ding, D, Hou, T.
登録日2022-06-08
公開日2023-06-14
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix.
Nat Commun, 14, 2023
5HLP
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BU of 5hlp by Molmil
X-RAY CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH BRD3937
分子名称: 4-(2-methoxyphenyl)-3,7,7-trimethyl-1,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta
著者White, A, Lakshminarasimhan, D, Nadupalli, A, Suto, R.K.
登録日2016-01-15
公開日2016-05-25
最終更新日2016-07-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects.
Acs Chem.Biol., 11, 2016
7YXY
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Cryo-EM structure of USP9X, local refinement of monomer
分子名称: Probable ubiquitin carboxyl-terminal hydrolase FAF-X
著者Deme, J.C, Halabelian, L, Arrowsmith, C.H, Lea, S.M, Structural Genomics Consortium (SGC)
登録日2022-02-16
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structure of USP9X
To Be Published
7YXX
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Cryo-EM structure of USP9X
分子名称: Probable ubiquitin carboxyl-terminal hydrolase FAF-X
著者Deme, J.C, Halabelian, L, Arrowsmith, C.H, Lea, S.M, Structural Genomics Consortium (SGC)
登録日2022-02-16
公開日2022-03-02
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of USP9X
To Be Published
5HZM
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Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae)
分子名称: Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN ATOM OR ION
著者DONG, A, ZENG, H, WALKER, J.R, Seitova, A, Hutchinson, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, MIN, J, WU, H, Structural Genomics Consortium (SGC)
登録日2016-02-02
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural basis of arginine asymmetrical dimethylation by PRMT6.
Biochem. J., 473, 2016
8F36
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Ubx Homeodomain NMR solution structure
分子名称: Homeotic protein ultrabithorax
著者Beasley, S.A, Loss, J.W, Mekkaoui, F, Advocate, M.R, Spratt, D.E.
登録日2022-11-09
公開日2023-04-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Ubx Homeodomain NMR solution structure
To Be Published
8F37
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AbdA Homeodomain NMR Solution Structure
分子名称: Homeobox protein abdominal-A
著者Beasley, S.A, Simons, R.A, Advocate, M.R, Mekkaoui, F, Spratt, D.E.
登録日2022-11-09
公開日2023-04-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献AbdA Homeodomain NMR solution structure
To Be Published
8EQG
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Human PU.1 ETS-Domain (165-270) Bound to d(AATAAA(DU)GGAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*DU*AP*AP*AP*TP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*AP*TP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2022-10-07
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EKV
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Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGATGTGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*TP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*AP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2022-09-22
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023

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