2NYJ
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2O8D
| human MutSalpha (MSH2/MSH6) bound to ADP and a G dU mispair | 分子名称: | 5'-D(*CP*CP*TP*AP*GP*CP*GP*(DU)P*GP*CP*GP*GP*TP*TP*C)-3', 5'-D(*GP*AP*AP*CP*CP*GP*CP*GP*CP*GP*CP*TP*AP*GP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Warren, J.J, Pohlhaus, T.J, Changela, A, Modrich, P.L, Beese, L.S. | 登録日 | 2006-12-12 | 公開日 | 2007-06-05 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of the Human MutSalpha DNA Lesion Recognition Complex. Mol.Cell, 26, 2007
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2OAE
| Crystal structure of rat dipeptidyl peptidase (DPPIV) with thiazole-based peptide mimetic #31 | 分子名称: | Dipeptidyl peptidase 4, N-{[(3S,5S)-5-(1,3-THIAZOLIDIN-3-YLCARBONYL)PYRROLIDIN-3-YL]METHYL}-1,3-THIAZOLE-4-CARBOXAMIDE, SULFATE ION | 著者 | Longenecker, K.L, Shuai, Q, Patel, J, Wiedeman, P. | 登録日 | 2006-12-15 | 公開日 | 2007-02-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit. Bioorg.Med.Chem.Lett., 17, 2007
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2OJI
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2OMV
| Crystal structure of InlA S192N Y369S/hEC1 complex | 分子名称: | CALCIUM ION, CHLORIDE ION, Epithelial-cadherin, ... | 著者 | Wollert, T, Heinz, D.W, Schubert, W.D. | 登録日 | 2007-01-23 | 公開日 | 2007-06-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Extending the host range of Listeria monocytogenes by rational protein design. Cell(Cambridge,Mass.), 129, 2007
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2OMY
| Crystal structure of InlA S192N/hEC1 complex | 分子名称: | CALCIUM ION, CHLORIDE ION, Epithelial-cadherin, ... | 著者 | Wollert, T, Heinz, D.W, Schubert, W.D. | 登録日 | 2007-01-23 | 公開日 | 2007-06-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Extending the host range of Listeria monocytogenes by rational protein design. Cell(Cambridge,Mass.), 129, 2007
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2OPH
| Human dipeptidyl peptidase IV in complex with an alpha amino acid inhibitor | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Scapin, G, Weber, A.E, Duffy, J.L. | 登録日 | 2007-01-29 | 公開日 | 2007-05-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | 4-Aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IV. Bioorg.Med.Chem.Lett., 17, 2007
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2ONC
| Crystal structure of human DPP-4 | 分子名称: | 2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Feng, J, Zhang, Z, Wallace, M.B, Stafford, J.A, Kaldor, S.W, Kassel, D.B, Navre, M, Shi, L, Skene, R.J, Asakawa, T, Takeuchi, K, Xu, R, Webb, D.R, Gwaltney, S.L. | 登録日 | 2007-01-23 | 公開日 | 2008-03-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV. J.Med.Chem., 50, 2007
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2OMU
| Crystal structure of InlA G194S+S Y369S/hEC1 complex | 分子名称: | CALCIUM ION, CHLORIDE ION, Epithelial-cadherin, ... | 著者 | Wollert, T, Heinz, D.W, Schubert, W.D. | 登録日 | 2007-01-23 | 公開日 | 2007-08-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2OR3
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2OMW
| Crystal structure of InlA S192N Y369S/mEC1 complex | 分子名称: | CHLORIDE ION, Epithelial-cadherin, Internalin-A | 著者 | Wollert, T, Heinz, D.W, Schubert, W.D. | 登録日 | 2007-01-23 | 公開日 | 2007-06-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Extending the host range of Listeria monocytogenes by rational protein design. Cell(Cambridge,Mass.), 129, 2007
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2OQI
| Human Dipeptidyl Peptidase IV (DPP4) with Piperidinone-constrained phenethylamine | 分子名称: | (4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE, Dipeptidyl peptidase 4 (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (Adenosine deaminase complexing protein 2) (ADABP) | 著者 | Pei, Z, Li, X, von Geldern, T.W, Longenecker, K.L, Pireh, D, Stewart, K.D, Backes, B.J, Lai, C, Lubben, T.H, Ballaron, S.J, Beno, D.W, Kempf-Grote, A.J, Sham, H.L, Trevillyan, J.M. | 登録日 | 2007-01-31 | 公開日 | 2007-04-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery and Structure-Activity Relationships of Piperidinone- and Piperidine-Constrained Phenethylamines as Novel, Potent, and Selective Dipeptidyl Peptidase IV Inhibitors. J.Med.Chem., 50, 2007
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2MPV
| Structural insight into host recognition and biofilm formation by aggregative adherence fimbriae of enteroaggregative Esherichia coli | 分子名称: | Major fimbrial subunit of aggregative adherence fimbria II AafA | 著者 | Matthews, S.J, Yang, Y, Berry, A.A, Pakharukova, N, Garnett, J.A, Lee, W, Cota, E, Liu, B, Roy, S, Tuittila, M, Marchant, J, Inman, K.G, Ruiz-Perez, F, Mandomando, I, Nataro, J.P, Zavialov, A.V. | 登録日 | 2014-06-04 | 公開日 | 2014-10-29 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural insight into host recognition by aggregative adherence fimbriae of enteroaggregative Escherichia coli. Plos Pathog., 10, 2014
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2MQS
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2NCS
| NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in the presence of dodecylphosphocholine micelles | 分子名称: | Envelope glycoprotein gp41 | 著者 | Jimenez, M, Nieva, J.L, Rujas, E, Partida-Hanon, A, Bruix, M. | 登録日 | 2016-04-14 | 公開日 | 2017-02-22 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface. Sci Rep, 6, 2016
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2OMX
| Crystal structure of InlA S192N G194S+S/hEC1 complex | 分子名称: | CALCIUM ION, CHLORIDE ION, Epithelial-cadherin, ... | 著者 | Wollert, T, Heinz, D.W, Schubert, W.D. | 登録日 | 2007-01-23 | 公開日 | 2007-08-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2OMZ
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2P8S
| Human dipeptidyl peptidase IV/CD26 in complex with a cyclohexalamine inhibitor | 分子名称: | (1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Scapin, G, Biftu, T. | 登録日 | 2007-03-23 | 公開日 | 2007-05-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin Bioorg.Med.Chem.Lett., 17, 2007
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2OMT
| Crystal structure of InlA G194S+S/hEC1 complex | 分子名称: | CALCIUM ION, CHLORIDE ION, Epithelial-cadherin; E-Cad/CTF1, ... | 著者 | Wollert, T, Heinz, D.W, Schubert, W.D. | 登録日 | 2007-01-23 | 公開日 | 2007-08-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2OQV
| Human Dipeptidyl Peptidase IV (DPP4) with piperidine-constrained phenethylamine | 分子名称: | (3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE, Dipeptidyl peptidase 4 (Dipeptidyl peptidase IV) (DPP IV) | 著者 | Pei, Z, Li, X, von Geldern, T.W, Longenecker, K.L, Pireh, D, Stewart, K.D. | 登録日 | 2007-02-01 | 公開日 | 2007-04-24 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery and Structure-Activity Relationships of Piperidinone- and Piperidine-Constrained Phenethylamines as Novel, Potent, and Selective Dipeptidyl Peptidase IV Inhibitors. J.Med.Chem., 50, 2007
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2KFZ
| KLENOW FRAGMENT WITH BRIDGING-SULFUR SUBSTRATE AND ZINC ONLY | 分子名称: | 5'-D(*GP*CP*TP*TP*AP*(US1)P*G)-3', KLENOW FRAGMENT OF DNA POLYMERASE I, MAGNESIUM ION, ... | 著者 | Brautigam, C.A, Sun, S, Piccirilli, J.A, Steitz, T.A. | 登録日 | 1998-07-02 | 公開日 | 1998-11-11 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli. Biochemistry, 38, 1999
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2K7Y
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2KFN
| KLENOW FRAGMENT WITH BRIDGING-SULFUR SUBSTRATE AND MANGANESE | 分子名称: | 5'-D(*GP*CP*TP*TP*AP*(US1)P*G)-3', KLENOW FRAGMENT OF DNA POLYMERASE I, MAGNESIUM ION, ... | 著者 | Brautigam, C.A, Sun, S, Piccirilli, J.A, Steitz, T.A. | 登録日 | 1998-07-01 | 公開日 | 1998-11-11 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli. Biochemistry, 38, 1999
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8HUH
| Crystal structure of T2R-TTL-3a complex | 分子名称: | 2-(1-methylindol-4-yl)-4-(3,4,5-trimethoxyphenyl)-1~{H}-imidazo[4,5-c]pyridine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Wang, Y.X, Chen, J.J. | 登録日 | 2022-12-23 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of T2R-TTL-3a complex To Be Published
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8I22
| Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester | 分子名称: | 7-ethoxy-7-oxidanylidene-heptanoic acid, Acyl-acyl carrier protein synthetase | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-13 | 公開日 | 2024-01-17 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.15 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester To Be Published
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