PDB: 45118 件ウェブページステータス検索Chemie searchBIRD

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4O5K	Structure of human DNA polymerase complexed with N7MG in the template base paired with incoming non-hydrolyzable CTP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.C, Lee, S. 登録日 2013-12-19 公開日 2014-07-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.058 Å) 主引用文献 Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine. Nucleic Acids Res., 42, 2014
4OBO	MAP4K4 in complex with inhibitor (compound 22), 6-(3-CHLOROPHENYL)QUINAZOLIN-4-AMINE 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(3-chlorophenyl)quinazolin-4-amine, Mitogen-activated protein kinase kinase kinase kinase 4, ... 著者 Harris, S.F, Wu, P, Coons, M. 登録日 2014-01-07 公開日 2014-04-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of Selective 4-Amino-pyridopyrimidine Inhibitors of MAP4K4 Using Fragment-Based Lead Identification and Optimization. J.Med.Chem., 57, 2014
4OA8	X-ray crystal structure of O-methyltransferase from Anaplasma phagocytophilum in apo form 分子名称: 1,2-ETHANEDIOL, O-methyltransferase family protein, SODIUM ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-01-03 公開日 2014-01-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 An O-Methyltransferase Is Required for Infection of Tick Cells by Anaplasma phagocytophilum. Plos Pathog., 11, 2015
6QVY	The Transcriptional Regulator PrfA-A94V mutant from Listeria Monocytogenes 分子名称: ISOPROPYL ALCOHOL, Listeriolysin regulatory protein, SODIUM ION 著者 Hall, M, Grundstrom, C, Hansen, S, Brannstrom, K, Johansson, J, Sauer-Eriksson, A.E. 登録日 2019-03-05 公開日 2020-04-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.686 Å) 主引用文献 A Novel Growth-Based Selection Strategy Identifies New Constitutively Active Variants of the Major Virulence Regulator PrfA in Listeria monocytogenes. J.Bacteriol., 202, 2020
4UBG	Resting state of rat cysteine dioxygenase C93G variant 分子名称: Cysteine dioxygenase type 1, FE (II) ION, SODIUM ION 著者 Fellner, M, Tchesnokov, E.P, Jameson, G.N, Wilbanks, S.M. 登録日 2014-08-13 公開日 2014-11-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Cys-Tyr Cross-Link of Cysteine Dioxygenase Changes the Optimal pH of the Reaction without a Structural Change. Biochemistry, 53, 2014
2GEZ	Crystal structure of potassium-independent plant asparaginase 分子名称: CHLORIDE ION, L-asparaginase alpha subunit, L-asparaginase beta subunit, ... 著者 Michalska, K, Bujacz, G, Jaskolski, M. 登録日 2006-03-21 公開日 2006-07-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of plant asparaginase. J.Mol.Biol., 360, 2006
5DBA	Structure of human DNA polymerase beta Host-Guest complex with the dG base paired with a dT 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Koag, M.C, Lee, S. 登録日 2015-08-21 公開日 2015-11-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.965 Å) 主引用文献 N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA. J.Am.Chem.Soc., 137, 2015
1MDG	An Alternating Antiparallel Octaplex in an RNA Crystal Structure 分子名称: 5'-R(*UP*(BGM)GP*AP*GP*GP*U)-3', COBALT HEXAMMINE(III), SODIUM ION 著者 Pan, B.C, Xiong, Y, Shi, K, Sundaralingam, M. 登録日 2002-08-07 公開日 2003-08-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 An Eight-Stranded Helical Fragment in RNA Crystal Structure: Implications for Tetraplex Interaction Structure, 11, 2003
2XYV	Crystal structure of the nsp16 nsp10 SARS coronavirus complex 分子名称: CHLORIDE ION, MAGNESIUM ION, NON-STRUCTURAL PROTEIN 10, ... 著者 Decroly, E, Debarnot, C, Ferron, F, Bouvet, M, Coutard, B, Imbert, I, Gluais, L, Papageorgiou, N, Ortiz-Lombardia, M, Lescar, J, Canard, B. 登録日 2010-11-19 公開日 2011-10-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex. Plos Pathog., 7, 2011
6Z55	Crystal structure of CLK3 in complex with macrocycle ODS2004070 分子名称: 1,2-ETHANEDIOL, 7,10-Dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxylic acid, Dual specificity protein kinase CLK3, ... 著者 Chaikuad, A, Benderitter, P, Hoflack, J, Denis, A, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2020-05-26 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of CLK3 in complex with macrocycle ODS2004070 To Be Published
2XRM	Processed Intracellular subtilisin from B. clausii 分子名称: CALCIUM ION, INTRACELLULAR SUBTILISIN PROTEASE, PENTAETHYLENE GLYCOL, ... 著者 Gamble, M, Kunze, G, Dodson, E.J, Jones, D.D, Wilson, K.S. 登録日 2010-09-20 公開日 2011-03-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Regulation of an Intracellular Subtilisin Protease Activity by a Short Propeptide Sequence Through an Original Combined Dual Mechanism. Proc.Natl.Acad.Sci.USA, 108, 2011
6YSU	Structure of the P+0 ArfB-ribosome complex in the post-hydrolysis state 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V. 登録日 2020-04-23 公開日 2020-08-19 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Mechanism of ribosome rescue by alternative ribosome-rescue factor B. Nat Commun, 11, 2020
5D4B	Structural Basis for a New Templated Activity by Terminal Deoxynucleotidyl Transferase: Implications for V(D)J Recombination 分子名称: DNA (5'-D(*AP*AP*AP*AP*AP*C)-3'), DNA (5'-D(*TP*TP*TP*TP*TP*GP*G)-3'), MAGNESIUM ION, ... 著者 Loc'h, J, Rosario, S, Delarue, M. 登録日 2015-08-07 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Structural Basis for a New Templated Activity by Terminal Deoxynucleotidyl Transferase: Implications for V(D)J Recombination. Structure, 24, 2016
5CVY	The Structure of Bacillus pumilus GH48 in complex with cellobiose and cellohexaose 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ... 著者 Alahuhta, P.M, Lunin, V.V. 登録日 2015-07-27 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Natural diversity of glycoside hydrolase family 48 exoglucanases: insights from structure. Biotechnol Biofuels, 10, 2017
5DB8	Structure of human DNA polymerase beta Host-Guest complex with the N7MG base paired with a dA 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*AP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*(FMG)P*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Koag, M.C, Lee, S. 登録日 2015-08-21 公開日 2015-11-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.547 Å) 主引用文献 N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA. J.Am.Chem.Soc., 137, 2015
6ZJP	Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB mutant E517Q 分子名称: ACETATE ION, Beta-galactosidase, SODIUM ION 著者 Rutkiewicz, M, Bujacz, A, Bujacz, G. 登録日 2020-06-29 公開日 2020-08-05 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Mapping the Transglycosylation Relevant Sites of Cold-Adapted beta-d-Galactosidase fromArthrobactersp. 32cB. Int J Mol Sci, 21, 2020
5DBB	Structure of human DNA polymerase beta Host-Guest complex with the dG base paired with a dA 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*AP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Koag, M.C, Lee, S. 登録日 2015-08-21 公開日 2015-11-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA. J.Am.Chem.Soc., 137, 2015
5DB9	Structure of human DNA polymerase beta Host-Guest complex with the N7MG base paired with a dG 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*GP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*(FMG)P*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Koag, M.C, Lee, S. 登録日 2015-08-21 公開日 2015-11-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA. J.Am.Chem.Soc., 137, 2015
5DGU	Crystal Structure of HIV-1 Protease Inhibitors Containing Substituted fused-Tetrahydropyranyl Tetrahydrofuran as P2-Ligand GRL-004-11A 分子名称: (3R,3aR,4S,7aS)-3-methoxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, ACETATE ION, CHLORIDE ION, ... 著者 Agniswamy, J, Wang, Y.-F, Weber, I.T. 登録日 2015-08-28 公開日 2015-10-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Design, synthesis, biological evaluation and X-ray structural studies of HIV-1 protease inhibitors containing substituted fused-tetrahydropyranyl tetrahydrofuran as P2-ligands. Org.Biomol.Chem., 13, 2015
4WCN	Crystal Structure of Tripeptide bound Cell Shape Determinant Csd4 protein from Helicobacter pylori 分子名称: Conserved hypothetical secreted protein, IODIDE ION, N-acetyl-L-alanyl-N-[(1S,5R)-5-amino-1,5-dicarboxypentyl]-D-glutamine, ... 著者 Chan, A.C, Murphy, M.E. 登録日 2014-09-05 公開日 2014-12-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Helical Shape of Helicobacter pylori Requires an Atypical Glutamine as a Zinc Ligand in the Carboxypeptidase Csd4. J.Biol.Chem., 290, 2015
5DW1	X-ray crystal structure of human BRD2(BD2) in complex with RVX297 to 1.55 A resolution 分子名称: 2-{3,5-dimethyl-4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-5,7-dimethoxyquinazolin-4(3H)-one, Bromodomain-containing protein 2, SODIUM ION 著者 White, A, Fontano, E, Suto, R.K. 登録日 2015-09-22 公開日 2016-06-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 RVX-297- a novel BD2 selective inhibitor of BET bromodomains. Biochem.Biophys.Res.Commun., 477, 2016
5DLV	Crystal structure of Autotaxin (ENPP2) with tauroursodeoxycholic acid (TUDCA) 分子名称: 2-{[(3alpha,5beta,7alpha,8alpha,14beta,17alpha)-3,7-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonic acid, CALCIUM ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, ... 著者 Keune, W.J, Heidebrecht, T, von Castelmur, E, Joosten, R.P, Perrakis, A. 登録日 2015-09-07 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling. Nat Commun, 7, 2016
6DIA	DNA polymerase beta substrate complex with templating cytosine and incoming Fapy-dGTP analog 分子名称: 1-[2-amino-5-(formylamino)-6-oxo-1,6-dihydropyrimidin-4-yl]-2,5-anhydro-1,3-dideoxy-6-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-ribo-hexitol, CALCIUM ION, DNA (5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Freudenthal, B.D, Smith, M.R, Wilson, S.H, Beard, W.A. 登録日 2018-05-23 公開日 2019-01-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.969 Å) 主引用文献 A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition. Nucleic Acids Res., 47, 2019
6KKO	The crystal structure of SiaB-SiaC complex from Pseudomonas aeruginosa 分子名称: ADENOSINE-5'-DIPHOSPHATE, DUF1987 domain-containing protein, Putative serine phosphatase, ... 著者 Gan, J.H, Yang, C. 登録日 2019-07-26 公開日 2020-06-10 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 The SiaA/B/C/D signaling network regulates biofilm formation in Pseudomonas aeruginosa. Embo J., 39, 2020
6KFN	Crystal structure of alginate lyase from Paenibacillus sp. str. FPU-7 分子名称: IMIDAZOLE, SODIUM ION, alginate lyase 著者 Itoh, T, Nakagawa, E, Yoda, M, Nakaichi, A, Hibi, T, Kimoto, H. 登録日 2019-07-08 公開日 2019-10-30 実験手法 X-RAY DIFFRACTION (0.89 Å) 主引用文献 Structural and biochemical characterisation of a novel alginate lyase from Paenibacillus sp. str. FPU-7. Sci Rep, 9, 2019

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