2QHZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qhz by Molmil](/molmil-images/mine/2qhz) | Crystal structure of protease inhibitor, MIT-1-AC87 in complex with wild type HIV-1 protease | 分子名称: | (2E)-N-[(1S,2R)-1-BENZYL-2-HYDROXY-3-{(2-THIENYLMETHYL)[(2,4,5-TRIFLUOROPHENYL)SULFONYL]AMINO}PROPYL]-4,4,4-TRIFLUORO-3-METHYLBUT-2-ENAMIDE, PHOSPHATE ION, Protease | 著者 | Schiffer, C.A, Nalam, M.N.L. | 登録日 | 2007-07-03 | 公開日 | 2008-04-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants. J.Am.Chem.Soc., 130, 2008
|
|
2QHY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qhy by Molmil](/molmil-images/mine/2qhy) | Crystal Structure of protease inhibitor, MIT-1-AC86 in complex with wild type HIV-1 protease | 分子名称: | ACETATE ION, N~2~-ACETYL-N-[(1S,2R)-1-BENZYL-2-HYDROXY-3-{(2-THIENYLMETHYL)[(2,4,5-TRIFLUOROPHENYL)SULFONYL]AMINO}PROPYL]-L-ALANINAMIDE, PHOSPHATE ION, ... | 著者 | Schiffer, C.A, Nalam, M.N.L. | 登録日 | 2007-07-03 | 公開日 | 2008-04-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants. J.Am.Chem.Soc., 130, 2008
|
|
2QI0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qi0 by Molmil](/molmil-images/mine/2qi0) | |
5EM1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5em1 by Molmil](/molmil-images/mine/5em1) | Crystal structure of ragweed allergen Amb a 8 | 分子名称: | BENZOIC ACID, CHLORIDE ION, Profilin | 著者 | Offermann, L.R, He, J.Z, Perdue, M.L, Chruszcz, M. | 登録日 | 2015-11-05 | 公開日 | 2016-06-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2. J.Biol.Chem., 291, 2016
|
|
5EVE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5eve by Molmil](/molmil-images/mine/5eve) | Crystal structure of Amb a 8 in complex with poly-Pro10 | 分子名称: | Poly-Proline peptide, Profilin | 著者 | Offermann, L.R, Schlachter, C.R, Garrett, J, Chruszcz, M. | 登録日 | 2015-11-19 | 公開日 | 2016-06-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2. J.Biol.Chem., 291, 2016
|
|
2MM0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mm0 by Molmil](/molmil-images/mine/2mm0) | Solution Structures of active Ptr ToxB and its inactive homolog highlight protein dynamics as a modulator of toxin activity | 分子名称: | Host-selective toxin protein | 著者 | Nyarko, A, Singarapu, K, Figueroa, M, Manning, V, Pandelova, I, Wolpert, T, Ciuffetti, L, Barbar, E. | 登録日 | 2014-03-06 | 公開日 | 2014-08-06 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structures of Pyrenophora tritici-repentis ToxB and Its Inactive Homolog Reveal Potential Determinants of Toxin Activity. J.Biol.Chem., 289, 2014
|
|
5FUA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fua by Molmil](/molmil-images/mine/5fua) | Cryo-EM of BK polyomavirus | 分子名称: | MAJOR CAPSID PROTEIN VP1 | 著者 | Hurdiss, D.L, Morgan, E.L, Thompson, R.F, Prescott, E.L, Panou, M.M, Macdonald, A, Ranson, N.A. | 登録日 | 2016-01-22 | 公開日 | 2016-04-20 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | 主引用文献 | New Structural Insights Into the Genome and Minor Capsid Proteins of Bk Polyomavirus Using Cryo-Electron Microscopy. Structure, 24, 2016
|
|
5FRR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5frr by Molmil](/molmil-images/mine/5frr) | Structure of the Pds5-Scc1 complex and implications for cohesin function | 分子名称: | SISTER CHROMATID COHESION PROTEIN PDS5 | 著者 | Muir, K.W, Kschonsak, M, Li, Y, Metz, J, Haering, C.H, Panne, D. | 登録日 | 2015-12-22 | 公開日 | 2016-03-02 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (5.8 Å) | 主引用文献 | Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function Cell Rep., 14, 2016
|
|
3WHW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3whw by Molmil](/molmil-images/mine/3whw) | MTH1 in complex with Ruthenium-based inhibitor | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION, [4-amino-2-methyl-6-(pyridin-2-yl-kappaN)quinazolin-7-yl-kappaC~7~](carbonyl){1-[(2,6-dimethoxyphenoxy)carbonyl]cyclopenta-2,4-dien-1-yl}ruthenium | 著者 | Streib, M, Kraeling, K, Richter, K, Steuber, H, Meggers, E. | 登録日 | 2013-09-03 | 公開日 | 2014-02-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | 主引用文献 | An Organometallic Inhibitor for the Human Repair Enzyme 7,8-Dihydro-8-oxoguanosine Triphosphatase. Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
5G2E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5g2e by Molmil](/molmil-images/mine/5g2e) | Structure of the Nap1 H2A H2B complex | 分子名称: | HISTONE H2A TYPE 1, HISTONE H2B 1.1, NUCLEOSOME ASSEMBLY PROTEIN | 著者 | AguilarGurrieri, C, Larabi, A, Vinayachandran, V, Patel, N.A, Yen, K, Reja, R, Ebong, I.O, Schoehn, G, Robinson, C.V, Pugh, B.F, Panne, D. | 登録日 | 2016-04-07 | 公開日 | 2016-08-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (6.7 Å) | 主引用文献 | Structural Evidence for Nap1-Dependent H2A-H2B Deposition and Nucleosome Assembly. Embo J., 35, 2016
|
|
5G1S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5g1s by Molmil](/molmil-images/mine/5g1s) | Open conformation of Francisella tularensis ClpP at 1.7 A | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... | 著者 | Diaz-Saez, L, Pankov, G, Hunter, W.N. | 登録日 | 2016-03-30 | 公開日 | 2016-10-19 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Open and compressed conformations of Francisella tularensis ClpP. Proteins, 85, 2017
|
|
5GMU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gmu by Molmil](/molmil-images/mine/5gmu) | Crystal structure of chorismate mutase like domain of bifunctional DAHP synthase of Bacillus subtilis in complex with Chlorogenic acid | 分子名称: | (1R,3R,4S,5R)-3-[3-[3,4-bis(oxidanyl)phenyl]propanoyloxy]-1,4,5-tris(oxidanyl)cyclohexane-1-carboxylic acid, Protein AroA(G), SULFATE ION | 著者 | Pratap, S, Dev, A, Sharma, V, Yadav, R, Narwal, M, Tomar, S, Kumar, P. | 登録日 | 2016-07-16 | 公開日 | 2017-07-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of Chorismate Mutase-like Domain of DAHPS from Bacillus subtilis Complexed with Novel Inhibitor Reveals Conformational Plasticity of Active Site. Sci Rep, 7, 2017
|
|
2MUQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2muq by Molmil](/molmil-images/mine/2muq) | |
2MZC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mzc by Molmil](/molmil-images/mine/2mzc) | Metal Binding of Glutaredoxins | 分子名称: | Glutaredoxin, SILVER ION | 著者 | Bilinovich, S.M, Caporoso, J.A, Taraboletti, A, Duangjumpa, N, Panzner, M.J, Prokop, J.W, Shriver, L.P, Leeper, T.C. | 登録日 | 2015-02-11 | 公開日 | 2016-04-13 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Metal Binding of Glutaredoxins To be Published
|
|
5G64
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5g64 by Molmil](/molmil-images/mine/5g64) | The complex between human IgE-Fc and two anti-IgE Fab fragments | 分子名称: | FAB FRAGMENT, IG EPSILON CHAIN C REGION, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Davies, A.M, Allan, E.G, Keeble, A.H, Delgado, J, Cossins, B.P, Mitropoulou, A.N, Pang, M.O.Y, Ceska, T, Beavil, A.J, Craggs, G, Westwood, M, Henry, A.J, McDonnell, J.M, Sutton, B.J. | 登録日 | 2016-06-14 | 公開日 | 2017-05-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.715 Å) | 主引用文献 | Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab. J. Biol. Chem., 292, 2017
|
|
5NYW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5nyw by Molmil](/molmil-images/mine/5nyw) | Anbu (ancestral beta-subunit) from Yersinia bercovieri | 分子名称: | 1,2-ETHANEDIOL, AZIDE ION, CHLORIDE ION, ... | 著者 | Piasecka, A, Czapinska, H, Vielberg, M, Szczepanowski, R.H, Reed, S, Groll, M, Bochtler, M. | 登録日 | 2017-05-12 | 公開日 | 2017-05-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | The Y. bercovieri Anbu crystal structure sheds light on the evolution of highly (pseudo)symmetric multimers. J. Mol. Biol., 430, 2018
|
|
2MUR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mur by Molmil](/molmil-images/mine/2mur) | |
4NCI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nci by Molmil](/molmil-images/mine/4nci) | Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation | 分子名称: | DNA double-strand break repair Rad50 ATPase | 著者 | Classen, S, Williams, G.J, Arvai, A.S, Williams, R.S. | 登録日 | 2013-10-24 | 公開日 | 2014-03-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling. Embo J., 33, 2014
|
|
4NCJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ncj by Molmil](/molmil-images/mine/4ncj) | Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation with ADP Beryllium Flouride | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA double-strand break repair Rad50 ATPase, ... | 著者 | Classen, S, Williams, G.J, Arvai, A.S, Williams, R.S. | 登録日 | 2013-10-24 | 公開日 | 2014-03-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling. Embo J., 33, 2014
|
|
4DZY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4dzy by Molmil](/molmil-images/mine/4dzy) | Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/(S)-2-chloro-3-phenylpropanoic acid complex with ADP | 分子名称: | (S)-2-chloro-3-phenylpropanoic acid, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Tso, S.C, Chuang, J.L, Gui, W.J, Wynn, R.M, Li, J, Chuang, D.T. | 登録日 | 2012-03-01 | 公開日 | 2013-03-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
2OAA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2oaa by Molmil](/molmil-images/mine/2oaa) | Restriction endonuclease MvaI-cognate DNA substrate complex | 分子名称: | 5'-D(*CP*AP*TP*CP*CP*AP*GP*GP*TP*AP*C)-3', 5'-D(*GP*GP*TP*AP*CP*CP*TP*GP*GP*AP*T)-3', CALCIUM ION, ... | 著者 | Kaus-Drobek, M, Czapinska, H, Sokolowska, M, Tamulaitis, G, Szczepanowski, R.H, Urbanke, K, Siksnys, V, Bochtler, M. | 登録日 | 2006-12-15 | 公開日 | 2007-02-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically. Nucleic Acids Res., 35, 2007
|
|
5FIS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fis by Molmil](/molmil-images/mine/5fis) | Exonuclease domain-containing 1 (Exd1) in the Gd bound conformation | 分子名称: | EXD1, GADOLINIUM ATOM | 著者 | Yang, Z, Chen, K.M, Pandey, R.R, Homolka, D, Reuter, M, Rodino Janeiro, B.K, Sachidanandam, R, Fauvarque, M.O, McCarthy, A.A, Pillai, R.S. | 登録日 | 2015-10-02 | 公開日 | 2015-12-23 | 最終更新日 | 2016-01-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Piwi Slicing and Exd1 Drive Biogenesis of Nuclear Pirnas from Cytosolic Targets of the Mouse Pirna Pathway Mol.Cell, 61, 2016
|
|
4NCK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nck by Molmil](/molmil-images/mine/4nck) | Crystal Structure of Pyrococcus furiosis Rad50 R797G mutation | 分子名称: | CHLORIDE ION, DNA double-strand break repair Rad50 ATPase, MAGNESIUM ION, ... | 著者 | Classen, S, Williams, G.J, Arvai, A.S, Williams, R.S. | 登録日 | 2013-10-24 | 公開日 | 2014-03-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling. Embo J., 33, 2014
|
|
4NCH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nch by Molmil](/molmil-images/mine/4nch) | Crystal Structure of Pyrococcus furiosis Rad50 L802W mutation | 分子名称: | DNA double-strand break repair Rad50 ATPase, SULFATE ION | 著者 | Classen, S, Williams, G.J, Arvai, A.S, Williams, R.S. | 登録日 | 2013-10-24 | 公開日 | 2014-03-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling. Embo J., 33, 2014
|
|
2NYX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2nyx by Molmil](/molmil-images/mine/2nyx) | Crystal structure of RV1404 from Mycobacterium tuberculosis | 分子名称: | Probable transcriptional regulatory protein, Rv1404 | 著者 | Yu, M, Bursey, E.H, Radhakannan, R, Kim, C.-Y, Kaviratne, T, Woodruff, T, Segelke, B.W, Lekin, T, Toppani, D, Terwilliger, T.C, Hung, L.-W, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI) | 登録日 | 2006-11-21 | 公開日 | 2006-12-05 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of RV1404 from Mycobacterium tuberculosis To be Published
|
|