8I0P
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![BU of 8i0p by Molmil](/molmil-images/mine/8i0p) | The cryo-EM structure of human pre-Bact complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | 著者 | Zhan, X, Lu, Y, Shi, Y. | 登録日 | 2023-01-11 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
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8CVJ
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![BU of 8cvj by Molmil](/molmil-images/mine/8cvj) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMSEAC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.40A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. | 登録日 | 2022-05-18 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes. Nat.Chem., 15, 2023
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8CVK
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![BU of 8cvk by Molmil](/molmil-images/mine/8cvk) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMRC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.50A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. | 登録日 | 2022-05-18 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes. Nat.Chem., 15, 2023
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8CVL
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![BU of 8cvl by Molmil](/molmil-images/mine/8cvl) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMTHSMRC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.30A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. | 登録日 | 2022-05-18 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes. Nat.Chem., 15, 2023
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1AQD
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![BU of 1aqd by Molmil](/molmil-images/mine/1aqd) | |
4A3E
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![BU of 4a3e by Molmil](/molmil-images/mine/4a3e) | RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid and soaked with AMPCPP | 分子名称: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ... | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | 登録日 | 2011-09-30 | 公開日 | 2011-12-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
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1ATG
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![BU of 1atg by Molmil](/molmil-images/mine/1atg) | AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, PERIPLASMIC MOLYBDATE-BINDING PROTEIN, ... | 著者 | Lawson, D.M, Pau, R.N, Williams, C.E.M, Mitchenall, L.A. | 登録日 | 1997-08-14 | 公開日 | 1998-10-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Ligand size is a major determinant of specificity in periplasmic oxyanion-binding proteins: the 1.2 A resolution crystal structure of Azotobacter vinelandii ModA. Structure, 6, 1998
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1BEG
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![BU of 1beg by Molmil](/molmil-images/mine/1beg) | STRUCTURE OF FUNGAL ELICITOR, NMR, 18 STRUCTURES | 分子名称: | BETA-ELICITIN CRYPTOGEIN | 著者 | Fefeu, S, Bouaziz, S, Huet, J.-C, Pernollet, J.-C, Guittet, E. | 登録日 | 1996-11-26 | 公開日 | 1997-12-03 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional solution structure of beta cryptogein, a beta elicitin secreted by a phytopathogenic fungus Phytophthora cryptogea. Protein Sci., 6, 1997
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8JLB
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![BU of 8jlb by Molmil](/molmil-images/mine/8jlb) | Cryo-EM structure of the 145 bp human nucleosome containing H3.2 C110A mutant | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-06-02 | 公開日 | 2023-10-04 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.36 Å) | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
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6PVK
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![BU of 6pvk by Molmil](/molmil-images/mine/6pvk) | Bacterial 45SRbgA ribosomal particle class A | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Ortega, J, Seffouh, A, Jain, N, Jahagirdar, D, Basu, K, Razi, A, Ni, X, Guarne, A, Britton, R.A. | 登録日 | 2019-07-20 | 公開日 | 2019-09-18 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural consequences of the interaction of RbgA with a 50S ribosomal subunit assembly intermediate. Nucleic Acids Res., 47, 2019
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6Q22
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![BU of 6q22 by Molmil](/molmil-images/mine/6q22) | Coiled-coil Trimer with Glu:Aminobutyric acid:Lys Triad | 分子名称: | Coiled-coil Trimer with Glu:Aminobutyric acid:Lys Triad, PENTAETHYLENE GLYCOL | 著者 | Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L. | 登録日 | 2019-08-06 | 公開日 | 2020-04-29 | 最終更新日 | 2020-05-20 | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | 主引用文献 | Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle. Biochemistry, 59, 2020
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6Q25
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1AYX
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![BU of 1ayx by Molmil](/molmil-images/mine/1ayx) | CRYSTAL STRUCTURE OF GLUCOAMYLASE FROM SACCHAROMYCOPSIS FIBULIGERA AT 1.7 ANGSTROMS | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLUCOAMYLASE | 著者 | Sevcik, J, Hostinova, E, Gasperik, J, Solovicova, A, Wilson, K.S, Dauter, Z. | 登録日 | 1997-11-12 | 公開日 | 1998-05-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of glucoamylase from Saccharomycopsis fibuligera at 1.7 A resolution. Acta Crystallogr.,Sect.D, 54, 1998
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8UVR
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![BU of 8uvr by Molmil](/molmil-images/mine/8uvr) | Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with spectinomycin, mRNA, deacylated A- and E-site tRNAphe, and deacylated P-site tRNAmet at 2.60A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Killam, B.Y, Phelps, G.A, Lee, R.E, Polikanov, Y.S. | 登録日 | 2023-11-03 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus. Proc.Natl.Acad.Sci.USA, 121, 2024
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8UVS
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![BU of 8uvs by Molmil](/molmil-images/mine/8uvs) | Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with spectinomycin derivative 2694, mRNA, deacylated A- and E-site tRNAphe, and deacylated P-site tRNAmet at 2.75A resolution | 分子名称: | (2R,4R,4aS,5aR,6S,7S,8R,9S,9aR,10aS)-2-methyl-6,8-bis(methylamino)-4-({[2-(oxan-4-yl)ethyl]amino}methyl)octahydro-2H-pyrano[2,3-b][1,4]benzodioxine-4,4a,7,9(10aH)-tetrol, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | 著者 | Killam, B.Y, Phelps, G.A, Lee, R.E, Polikanov, Y.S. | 登録日 | 2023-11-03 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VTY
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![BU of 8vty by Molmil](/molmil-images/mine/8vty) | Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with ciprofloxacin and protein Y at 2.60A resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID, 16S Ribosomal RNA, ... | 著者 | Aleksandrova, E.V, Ma, C.-X, Klepacki, D, Alizadeh, F, Vazquez-Laslop, N, Liang, J.-H, Polikanov, Y.S, Mankin, A.S. | 登録日 | 2024-01-27 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms. Nat.Chem.Biol., 2024
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1BGY
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![BU of 1bgy by Molmil](/molmil-images/mine/1bgy) | CYTOCHROME BC1 COMPLEX FROM BOVINE | 分子名称: | CYTOCHROME BC1 COMPLEX, FE2/S2 (INORGANIC) CLUSTER, HEME C, ... | 著者 | Iwata, S, Lee, J.W, Okada, K, Lee, J.K, Iwata, M, Ramaswamy, S, Jap, B.K. | 登録日 | 1998-06-02 | 公開日 | 1999-01-06 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex. Science, 281, 1998
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7XN7
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![BU of 7xn7 by Molmil](/molmil-images/mine/7xn7) | RNA polymerase II elongation complex containing Spt4/5, Elf1, Spt6, Spn1 and Paf1C | 分子名称: | Chromatin elongation factor SPT5, Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, ... | 著者 | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | 登録日 | 2022-04-28 | 公開日 | 2022-09-07 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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1A7L
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![BU of 1a7l by Molmil](/molmil-images/mine/1a7l) | DOMINANT B-CELL EPITOPE FROM THE PRES2 REGION OF HEPATITIS B VIRUS IN THE FORM OF AN INSERTED PEPTIDE SEGMENT IN MALTODEXTRIN-BINDING PROTEIN | 分子名称: | MALE-B363, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Saul, F.A, Vulliez-Lenormand, B, Lema, F, Bentley, G.A. | 登録日 | 1998-03-16 | 公開日 | 1998-06-17 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of a dominant B-cell epitope from the preS2 region of hepatitis B virus in the form of an inserted peptide segment in maltodextrin-binding protein. J.Mol.Biol., 280, 1998
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8CWW
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![BU of 8cww by Molmil](/molmil-images/mine/8cww) | Structure of S. cerevisiae Hop1 CBR bound to a nucleosome | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | 著者 | Gu, Y, Ur, S.N, Milano, C.R, Tromer, E.C, Vale-Silva, L.A, Hochwagen, A, Corbett, K.D. | 登録日 | 2022-05-19 | 公開日 | 2023-06-07 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | 主引用文献 | Chromatin binding by HORMAD proteins regulates meiotic recombination initiation. Embo J., 43, 2024
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8CZE
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![BU of 8cze by Molmil](/molmil-images/mine/8cze) | Structure of a Xenopus Nucleosome with Widom 601 DNA | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | 著者 | Gu, Y, Ur, S.N, Milano, C.R, Tromer, E.C, Vale-Silva, L.A, Hochwagen, A, Corbett, K.D. | 登録日 | 2022-05-24 | 公開日 | 2023-06-07 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Chromatin binding by HORMAD proteins regulates meiotic recombination initiation. Embo J., 43, 2024
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2FTC
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![BU of 2ftc by Molmil](/molmil-images/mine/2ftc) | Structural Model for the Large Subunit of the Mammalian Mitochondrial Ribosome | 分子名称: | 39S ribosomal protein L11, mitochondrial, 39S ribosomal protein L12, ... | 著者 | Mears, J.A, Sharma, M.R, Gutell, R.R, Richardson, P.E, Agrawal, R.K, Harvey, S.C. | 登録日 | 2006-01-24 | 公開日 | 2006-04-11 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (12.1 Å) | 主引用文献 | A Structural Model for the Large Subunit of the Mammalian Mitochondrial Ribosome J.Mol.Biol., 358, 2006
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4A3M
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![BU of 4a3m by Molmil](/molmil-images/mine/4a3m) | RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid and soaked with AMPCPP | 分子名称: | 5'-D(*AP*AP*GP*TP*AP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP* TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*GP*GP*A)-3', ... | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | 登録日 | 2011-09-30 | 公開日 | 2011-12-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
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1AT6
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![BU of 1at6 by Molmil](/molmil-images/mine/1at6) | HEN EGG WHITE LYSOZYME WITH A ISOASPARTATE RESIDUE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LYSOZYME | 著者 | Noguchi, S, Miyawaki, K, Satow, Y. | 登録日 | 1997-08-19 | 公開日 | 1998-02-25 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Succinimide and isoaspartate residues in the crystal structures of hen egg-white lysozyme complexed with tri-N-acetylchitotriose. J.Mol.Biol., 278, 1998
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4A3B
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![BU of 4a3b by Molmil](/molmil-images/mine/4a3b) | RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid | 分子名称: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | 登録日 | 2011-09-30 | 公開日 | 2011-12-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
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