PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

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1H2A	SINGLE CRYSTALS OF HYDROGENASE FROM DESULFOVIBRIO VULGARIS 分子名称: FE3-S4 CLUSTER, HYDROGENASE, IRON/SULFUR CLUSTER, ... 著者 Higuchi, Y, Yasuoka, N. 登録日 1997-10-17 公開日 1999-02-09 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Unusual ligand structure in Ni-Fe active center and an additional Mg site in hydrogenase revealed by high resolution X-ray structure analysis. Structure, 5, 1997
7E3H	Crystal structure of human acetylcholinesterase in complex with donepezil 分子名称: 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase 著者 Dileep, K.V, Ihara, K, Mishima-Tsumagari, C, Kukimoto-Niino, M, Yonemochi, M, Hanada, K, Shirouzu, M, Zhang, K.Y.J. 登録日 2021-02-08 公開日 2022-02-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery Int.J.Biol.Macromol., 210, 2022
1GRB	SUBSTRATE BINDING AND CATALYSIS BY GLUTATHIONE REDUCTASE AS DERIVED FROM REFINED ENZYME: SUBSTRATE CRYSTAL STRUCTURES AT 2 ANGSTROMS RESOLUTION 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Karplus, P.A, Schulz, G.E. 登録日 1992-12-15 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Substrate binding and catalysis by glutathione reductase as derived from refined enzyme: substrate crystal structures at 2 A resolution. J.Mol.Biol., 210, 1989
1BMR	ALPHA-LIKE TOXIN LQH III FROM SCORPION LEIURUS QUINQUESTRIATUS HEBRAEUS, NMR, 25 STRUCTURES 分子名称: LQH III ALPHA-LIKE TOXIN 著者 Krimm, I, Gilles, N, Sautiere, P, Stankiewicz, M, Pelhate, M, Gordon, D, Lancelin, J.-M. 登録日 1998-07-24 公開日 1999-02-16 最終更新日 2022-02-16 実験手法 SOLUTION NMR 主引用文献 NMR structures and activity of a novel alpha-like toxin from the scorpion Leiurus quinquestriatus hebraeus. J.Mol.Biol., 285, 1999
2L7J	Solution structure of the third Immunoglobulin-like domain of nectin-1 分子名称: Poliovirus receptor-related 1 著者 Clausen, O, Poulsen, F.M. 登録日 2010-12-13 公開日 2011-12-14 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution structure of the third Immunoglobulin-like domain of nectin-1 To be Published
6V8Q	Structure of an inner membrane protein required for PhoPQ regulated increases in outer membrane cardiolipin 分子名称: (9Z,21R,24R,30R,33R,44Z)-24,27,30-trihydroxy-18,24,30,36-tetraoxo-19,23,25,29,31,35-hexaoxa-24lambda~5~,30lambda~5~-dip hosphatripentaconta-9,44-diene-21,33-diyl (9Z,9'Z)di-octadec-9-enoate, CALCIUM ION, DODECYL-BETA-D-MALTOSIDE, ... 著者 Fan, J, Miller, S. 登録日 2019-12-11 公開日 2020-03-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.699585 Å) 主引用文献 Structure of an Inner Membrane Protein Required for PhoPQ-Regulated Increases in Outer Membrane Cardiolipin. Mbio, 11, 2020
7E73	Crystal structure of human ERK2 mutant (Y36H) 分子名称: Mitogen-activated protein kinase 1, SULFATE ION 著者 Park, Y.S, Kim, M, Ryu, S.E. 登録日 2021-02-25 公開日 2022-03-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Structural mechanism of inhibitor-resistance by ERK2 mutations Biodesign, 9, 2021
7E75	Crystal structure of human ERK2 mutant (G37C) 分子名称: Mitogen-activated protein kinase 1 著者 Park, Y.S, Kim, M, Ryu, S.E. 登録日 2021-02-25 公開日 2022-03-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.481 Å) 主引用文献 Structural mechanism of inhibitor-resistance by ERK2 mutations Biodesign, 9, 2021
1I7K	CRYSTAL STRUCTURE OF HUMAN MITOTIC-SPECIFIC UBIQUITIN-CONJUGATING ENZYME, UBCH10 分子名称: UBIQUITIN-CONJUGATING ENZYME E2 H10 著者 Basavappa, R, Lin, Y. 登録日 2001-03-09 公開日 2001-04-04 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural and functional analysis of the human mitotic-specific ubiquitin-conjugating enzyme, UbcH10. J.Biol.Chem., 277, 2002
6USX	Identification of the Clinical Development Candidate MRTX849, a Covalent KRASG12C Inhibitor for the Treatment of Cancer 分子名称: 1-{4-[2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-7-(naphthalen-1-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]piperazin-1-yl}propan-1-one, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Vigers, G.P, Smith, D.J. 登録日 2019-10-28 公開日 2020-04-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Identification of the Clinical Development CandidateMRTX849, a Covalent KRASG12CInhibitor for the Treatment of Cancer. J.Med.Chem., 63, 2020
1HRA	THE SOLUTION STRUCTURE OF THE HUMAN RETINOIC ACID RECEPTOR-BETA DNA-BINDING DOMAIN 分子名称: RETINOIC ACID RECEPTOR, ZINC ION 著者 Knegtel, R.M.A, Katahira, M, Schilthuis, J.G, Bonvin, A.M.J.J, Boelens, R, Eib, D, Van Der Saag, P.T, Kaptein, R. 登録日 1993-07-25 公開日 1994-01-31 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The solution structure of the human retinoic acid receptor-beta DNA-binding domain. J.Biomol.NMR, 3, 1993
2LM2	NMR structures of the transmembrane domains of the AChR b2 subunit 分子名称: Neuronal acetylcholine receptor subunit beta-2 著者 Bondarenko, V, Mowrey, D, Tillman, T, Cui, T, Liu, L.T, Xu, Y, Tang, P. 登録日 2011-11-18 公開日 2012-03-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR structures of the transmembrane domains of the a4b2 nAChR. Biochim.Biophys.Acta, 1818, 2012
2LC6	Solution structure of Par-6 Q144C/L164C 分子名称: Par-6 著者 Volkman, B.F, Whitney, D.S, Peterson, F.C. 登録日 2011-04-25 公開日 2011-11-30 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 A Conformational Switch in the CRIB-PDZ Module of Par-6. Structure, 19, 2011
6UZY	Cryo-EM structure of Xenopus tropicalis pannexin 1 分子名称: HEXADECANE, Pannexin, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate 著者 Deng, Z, He, Z, Yuan, P. 登録日 2019-11-15 公開日 2020-04-01 最終更新日 2020-04-22 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Cryo-EM structures of the ATP release channel pannexin 1. Nat.Struct.Mol.Biol., 27, 2020
6UT0	Identification of the Clinical Development Candidate MRTX849, a Covalent KRASG12C Inhibitor for the Treatment of Cancer 分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Vigers, G.P, Smith, D.J. 登録日 2019-10-29 公開日 2020-04-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Identification of the Clinical Development CandidateMRTX849, a Covalent KRASG12CInhibitor for the Treatment of Cancer. J.Med.Chem., 63, 2020
7ENQ	Crystal structure of human NAMPT in complex with compound NAT 分子名称: 2-(2-~{tert}-butylphenoxy)-~{N}-(4-hydroxyphenyl)ethanamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION 著者 Wang, G, Wu, C, Liu, M, Yao, H, Li, C, Wang, L, Tang, Y. 登録日 2021-04-19 公開日 2022-05-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.204966 Å) 主引用文献 Discovery of small-molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and their preclinical neuroprotective activity. Cell Res., 32, 2022
1CKT	CRYSTAL STRUCTURE OF HMG1 DOMAIN A BOUND TO A CISPLATIN-MODIFIED DNA DUPLEX 分子名称: Cisplatin, DNA (5'-D(*CP*CP*(5IU)P*CP*TP*CP*TP*GP*GP*AP*CP*CP*TP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*GP*TP*CP*CP*AP*GP*AP*GP*AP*GP*G)-3'), ... 著者 Ohndorf, U.-M, Rould, M.A, Pabo, C.O, Lippard, S.J. 登録日 1999-04-23 公開日 1999-06-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins. Nature, 399, 1999
6VAM	Cryo-EM structure of octameric chicken CALHM1 分子名称: Green fluorescent protein,CALHM1 chimera 著者 Syrjanen, J.L, Chou, T.H, Furukawa, H. 登録日 2019-12-17 公開日 2020-01-29 最終更新日 2020-11-11 実験手法 ELECTRON MICROSCOPY (3.63 Å) 主引用文献 Structure and assembly of calcium homeostasis modulator proteins. Nat.Struct.Mol.Biol., 27, 2020
2LUC	Solution Structure of human S100 calcium-binding protein A11 分子名称: Protein S100-A11 著者 Hung, K.W, Chang, Y.M, Yu, C. 登録日 2012-06-12 公開日 2013-05-22 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR structure note: the structure of human calcium-bound S100A11. J.Biomol.Nmr, 54, 2012
1H1K	THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA 分子名称: RNA 著者 Diprose, J.M, Grimes, J.M, Sutton, G.C, Burroughs, J.N, Meyer, A, Maan, S, Mertens, P.P.C, Stuart, D.I. 登録日 2002-07-17 公開日 2002-09-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (10 Å) 主引用文献 The Core of Bluetongue Virus Binds Double-Stranded RNA J.Virol., 76, 2002
1BSI	HUMAN PANCREATIC ALPHA-AMYLASE FROM PICHIA PASTORIS, GLYCOSYLATED PROTEIN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, CALCIUM ION, ... 著者 Rydberg, E.H, Sidhu, G, Vo, H.C, Hewitt, J, Cote, H.C.F, Wang, Y, Numao, S, Macgillivray, R.T.A, Overall, C.M, Brayer, G.D, Withers, S.G. 登録日 1998-08-28 公開日 1999-05-18 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Cloning, mutagenesis, and structural analysis of human pancreatic alpha-amylase expressed in Pichia pastoris. Protein Sci., 8, 1999
7EOK	Crystal structure of the Pepper aptamer in complex with HBC485 分子名称: 4-[(~{Z})-1-cyano-2-[5-[2-(dimethylamino)ethyl-methyl-amino]pyrazin-2-yl]ethenyl]benzenecarbonitrile, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Huang, K.Y, Ren, A.M. 登録日 2021-04-22 公開日 2021-11-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure-based investigation of fluorogenic Pepper aptamer. Nat.Chem.Biol., 17, 2021
7EOO	Crystal structure of the Pepper aptamer in complex with HBC525 分子名称: (~{E})-2-(1,3-benzoxazol-2-yl)-3-[4-[2-hydroxyethyl(methyl)amino]phenyl]prop-2-enenitrile, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Huang, K.Y, Ren, A.M. 登録日 2021-04-22 公開日 2021-11-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Structure-based investigation of fluorogenic Pepper aptamer. Nat.Chem.Biol., 17, 2021
7EOP	Crystal structure of the Pepper aptamer in complex with HBC620 分子名称: 4-[(~{Z})-1-cyano-2-[5-[2-hydroxyethyl(methyl)amino]thieno[3,2-b]thiophen-2-yl]ethenyl]benzenecarbonitrile, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Huang, K.Y, Ren, A.M. 登録日 2021-04-22 公開日 2021-11-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-based investigation of fluorogenic Pepper aptamer. Nat.Chem.Biol., 17, 2021
7EOL	Crystal structure of the Pepper aptamer in complex with HBC497 分子名称: 4-[(~{Z})-1-cyano-2-[5-[2-hydroxyethyl(methyl)amino]pyrazin-2-yl]ethenyl]benzenecarbonitrile, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Huang, K.Y, Ren, A.M. 登録日 2021-04-22 公開日 2021-11-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.309 Å) 主引用文献 Structure-based investigation of fluorogenic Pepper aptamer. Nat.Chem.Biol., 17, 2021

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