PDB: 2232 件ウェブページステータス検索Chemie searchBIRD

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2QCF	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP 分子名称: 5-FLUORO-URIDINE-5'-MONOPHOSPHATE, GLYCEROL, Uridine 5'-monophosphate synthase (UMP synthase) 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
2QCL	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to OMP 分子名称: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase) 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
2QCM	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 6-hydroxymethyl-UMP 分子名称: 6-(HYDROXYMETHYL)URIDINE 5'-(DIHYDROGEN PHOSPHATE), Uridine 5'-monophosphate synthase (UMP synthase) 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
3PF1	E. coli FadL Asp348Ala mutant 分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, LAURYL DIMETHYLAMINE-N-OXIDE, Long-chain fatty acid transport protein 著者 Vandenberg, B, Lepore, B.W, Hearn, E.M, Indic, M, Patel, D. 登録日 2010-10-27 公開日 2011-05-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 From the Cover: Ligand-gated diffusion across the bacterial outer membrane. Proc.Natl.Acad.Sci.USA, 108, 2011
1EYU	HIGH RESOLUTION STRUCTURE OF THE PVUII ENDONCULEASE/COGNATE DNA COMPLEX AT PH 4.6 分子名称: DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C)-3'), TYPE II RESTRICTION ENZYME PVUII 著者 Horton, J.R, Cheng, X. 登録日 2000-05-09 公開日 2000-07-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 PvuII endonuclease contains two calcium ions in active sites. J.Mol.Biol., 300, 2000
1F0O	PVUII ENDONUCLEASE/COGNATE DNA COMPLEX (GLUTARALDEHYDE-CROSSLINKED CRYSTAL) AT PH 7.5 WITH TWO CALCIUM IONS AT EACH ACTIVE SITE 分子名称: (5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C-3'), CALCIUM ION, TYPE II RESTRICTION ENZYME PVUII 著者 Horton, J.R, Cheng, X. 登録日 2000-05-16 公開日 2000-11-06 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 PvuII endonuclease contains two calcium ions in active sites. J.Mol.Biol., 300, 2000
4CHM	Structure of Inner Membrane Complex (IMC) Sub-compartment Protein 1 (ISP1) from Toxoplasma gondii 分子名称: IMC SUB-COMPARTMENT PROTEIN ISP1, SULFATE ION 著者 Tonkin, M.L, Beck, J.R, Bradley, P.J, Boulanger, M.J. 登録日 2013-12-03 公開日 2014-04-09 最終更新日 2017-07-05 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Inner Membrane Complex Sub-Compartment Proteins Critical for Replication of the Apicomplexan Parasite Toxoplasma Gondii Adopt a Pleckstrin Homology Fold J.Biol.Chem., 289, 2014
1Q36	EPSP synthase (Asp313Ala) liganded with tetrahedral reaction intermediate 分子名称: 3-phosphoshikimate 1-carboxyvinyltransferase, 5-(1-CARBOXY-1-PHOSPHONOOXY-ETHOXYL)-4-HYDROXY-3-PHOSPHONOOXY-CYCLOHEX-1-ENECARBOXYLIC ACID, FORMIC ACID 著者 Eschenburg, S, Kabsch, W, Healy, M.L, Schonbrunn, E. 登録日 2003-07-28 公開日 2003-12-16 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A New View of the Mechanisms of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) and 5-Enolpyruvylshikimate-3-phosphate Synthase (AroA) Derived from X-ray Structures of Their Tetrahedral Reaction Intermediate States. J.Biol.Chem., 278, 2003
1Q3G	MurA (Asp305Ala) liganded with tetrahedral reaction intermediate 分子名称: 1,2-ETHANEDIOL, 3'-1-CARBOXY-1-PHOSPHONOOXY-ETHOXY-URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, UDP-N-acetylglucosamine 1-carboxyvinyltransferase 著者 Eschenburg, S, Kabsch, W, Healy, M.L, Schonbrunn, E. 登録日 2003-07-29 公開日 2003-12-16 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 A New View of the Mechanisms of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) and 5-Enolpyruvylshikimate-3-phosphate Synthase (AroA) Derived from X-ray Structures of Their Tetrahedral Reaction Intermediate States. J.Biol.Chem., 278, 2003
7FDK	SARS-COV-2 Spike RBDMACSp36 binding to mACE2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 著者 Wang, X, Cao, L. 登録日 2021-07-16 公開日 2021-08-25 最終更新日 2022-03-23 実験手法 ELECTRON MICROSCOPY (3.69 Å) 主引用文献 Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2. Nat Commun, 12, 2021
7FDI	SARS-COV-2 Spike RBDMACSp36 binding to hACE2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 著者 Wang, X, Cao, L. 登録日 2021-07-16 公開日 2021-08-25 最終更新日 2022-03-23 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2. Nat Commun, 12, 2021
5UTV	SARS-unique fold in the Rousettus Bat Coronavirus HKU9 分子名称: Papain-like proteinase 著者 Hammond, R.G, Tan, X, Johnson, M.A. 登録日 2017-02-15 公開日 2017-06-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 SARS-unique fold in the Rousettus bat coronavirus HKU9. Protein Sci., 26, 2017
5T02	Structural characterisation of mutant Asp39Ala of thioesterase (NmACH) from Neisseria meningitidis 分子名称: Acyl-CoA hydrolase, CHLORIDE ION, COENZYME A, ... 著者 Khandokar, Y.B, Srivastava, P, Forwood, J.K. 登録日 2016-08-15 公開日 2016-09-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural insights into GDP-mediated regulation of a bacterial acyl-CoA thioesterase. J. Biol. Chem., 292, 2017
3ONF	Crystal structure of Lupinus luteus S-adenosyl-L-homocysteine hydrolase in complex with cordycepin 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3'-DEOXYADENOSINE, Adenosylhomocysteinase, ... 著者 Brzezinski, K, Jaskolski, M. 登録日 2010-08-28 公開日 2011-08-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 High-resolution structures of complexes of plant S-adenosyl-L-homocysteine hydrolase (Lupinus luteus). Acta Crystallogr.,Sect.D, 68, 2012
3OND	Crystal structure of Lupinus luteus S-adenosyl-L-homocysteine hydrolase in complex with adenosine 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE, Adenosylhomocysteinase, ... 著者 Brzezinski, K, Jaskolski, M. 登録日 2010-08-28 公開日 2011-08-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 High-resolution structures of complexes of plant S-adenosyl-L-homocysteine hydrolase (Lupinus luteus). Acta Crystallogr.,Sect.D, 68, 2012
3ONE	Crystal structure of Lupinus luteus S-adenosyl-L-homocysteine hydrolase in complex with adenine 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENINE, Adenosylhomocysteinase, ... 著者 Brzezinski, K, Jaskolski, M. 登録日 2010-08-28 公開日 2011-08-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 High-resolution structures of complexes of plant S-adenosyl-L-homocysteine hydrolase (Lupinus luteus). Acta Crystallogr.,Sect.D, 68, 2012
1WBJ	wildtype tryptophan synthase complexed with glycerol phosphate 分子名称: PYRIDOXAL-5'-PHOSPHATE, SN-GLYCEROL-3-PHOSPHATE, SODIUM ION, ... 著者 Kulik, V, Weyand, M, Schlichting, I. 登録日 2004-11-01 公開日 2006-05-24 最終更新日 2019-05-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 On the Structural Basis of the Catalytic Mechanism and the Regulation of the Alpha Subunit of Tryptophan Synthase from Salmonella Typhimurium and Bx1 from Maize, Two Evolutionarily Related Enzymes. J.Mol.Biol., 352, 2005
1RD5	Crystal structure of Tryptophan synthase alpha chain homolog BX1: a member of the chemical plant defense system 分子名称: MALONIC ACID, Tryptophan synthase alpha chain, chloroplast 著者 Kulik, V, Hartmann, E, Weyand, M, Frey, M, Gierl, A, Niks, D, Dunn, M.F, Schlichting, I. 登録日 2003-11-05 公開日 2004-12-28 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes. J.Mol.Biol., 352, 2005
1TJR	Crystal structure of wild-type BX1 complexed with a sulfate ion 分子名称: BX1, SULFATE ION 著者 Kulik, V, Hartmann, E, Weyand, M, Frey, M, Gierl, A, Niks, D, Dunn, M.F, Schlichting, I. 登録日 2004-06-07 公開日 2005-08-30 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes. J.Mol.Biol., 352, 2005
1TJP	Crystal Structure Of Wild-Type Tryptophan Synthase Complexed With 1-[(2-hydroxylphenyl)amino]3-glycerolphosphate 分子名称: 1-[(2-HYDROXYLPHENYL)AMINO]3-GLYCEROLPHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... 著者 Kulik, V, Hartmann, E, Weyand, M, Frey, M, Gierl, A, Niks, D, Dunn, M.F, Schlichting, I. 登録日 2004-06-07 公開日 2005-12-27 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes. J.Mol.Biol., 352, 2005
3VFL	Structure, Function, Stability and Knockout Phenotype of Dihydrodipicolinate Synthase from Streptococcus pneumoniae 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Dihydrodipicolinate synthase, GLYCEROL, ... 著者 Gorman, M.A. 登録日 2012-01-10 公開日 2013-06-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structure, Function, Stability and Knockout Phenotype of Dihydrodipicolinate Synthase from Streptococcus pneumoniae To be Published
4B1W	Structure of the Phactr1 RPEL-2 domain bound to actin 分子名称: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Mouilleron, S, Wiezlak, M, O'Reilly, N, Treisman, R, McDonald, N.Q. 登録日 2012-07-12 公開日 2013-07-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity. Structure, 20, 2012
4B1X	Structure of the Phactr1 RPEL-2 bound to G-actin 分子名称: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Mouilleron, S, Wiezlak, M, O'Reilly, N, Treisman, R, McDonald, N.Q. 登録日 2012-07-12 公開日 2013-07-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity. Structure, 20, 2012
4FHA	Structure of Dihydrodipicolinate Synthase from Streptococcus pneumoniae,bound to pyruvate and lysine 分子名称: Dihydrodipicolinate synthase, LYSINE, SODIUM ION 著者 Perugini, M.A, Dogovski, C, Parker, M.W, Gorman, M.A. 登録日 2012-06-06 公開日 2013-09-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structure, Function, Stability and Knockout Phenotype of Dihydrodipicolinate Synthase from Streptococcus pneumoniae To be Published
5HYR	Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Stapled Peptide SRC2-SP2 and Estradiol 分子名称: ESTRADIOL, Estrogen receptor, GLYCEROL, ... 著者 Fanning, S.W, Speltz, T.E, Mayne, C.G, Tajkhorshid, E, Greene, G.L, Moore, T.W. 登録日 2016-02-01 公開日 2016-05-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.271 Å) 主引用文献 Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction. Angew.Chem.Int.Ed.Engl., 55, 2016

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