1TJP
Crystal Structure Of Wild-Type Tryptophan Synthase Complexed With 1-[(2-hydroxylphenyl)amino]3-glycerolphosphate
Summary for 1TJP
Entry DOI | 10.2210/pdb1tjp/pdb |
Related | 1QOP 1TJR |
Descriptor | Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 1-[(2-HYDROXYLPHENYL)AMINO]3-GLYCEROLPHOSPHATE, ... (6 entities in total) |
Functional Keywords | substrate channeling, transition state analog, enzymatic mechanism, allosteric regulation, lyase |
Biological source | Salmonella typhimurium More |
Total number of polymer chains | 2 |
Total formula weight | 72035.80 |
Authors | Kulik, V.,Hartmann, E.,Weyand, M.,Frey, M.,Gierl, A.,Niks, D.,Dunn, M.F.,Schlichting, I. (deposition date: 2004-06-07, release date: 2005-12-27, Last modification date: 2011-07-13) |
Primary citation | Kulik, V.,Hartmann, E.,Weyand, M.,Frey, M.,Gierl, A.,Niks, D.,Dunn, M.F.,Schlichting, I. On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes. J.Mol.Biol., 352:608-620, 2005 Cited by PubMed: 16120446DOI: 10.1016/j.jmb.2005.07.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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