7NAS
 
 | | Bacterial 30S ribosomal subunit assembly complex state A (multibody refinement for body domain of 30S ribosome) | | 分子名称: | 16S rRNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | | 登録日 | 2021-01-25 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
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6VLF
 | | Crystal structure of mouse alpha 1,6-fucosyltransferase, FUT8 in its Apo-form | | 分子名称: | 1,2-ETHANEDIOL, Alpha-(1,6)-fucosyltransferase, SULFATE ION | | 著者 | Jarva, M.A, Dramicanin, M, Lingford, J.P, Mao, R, John, A, Goddard-Borger, E. | | 登録日 | 2020-01-23 | | 公開日 | 2020-02-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis of substrate recognition and catalysis by fucosyltransferase 8.
J.Biol.Chem., 295, 2020
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6VOG
 | | Chloroplast ATP synthase (O2, CF1) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ... | | 著者 | Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L. | | 登録日 | 2020-01-30 | | 公開日 | 2020-09-09 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (4.35 Å) | | 主引用文献 | Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
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2IBS
 | | Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position | | 分子名称: | 5'-D(*GP*AP*CP*AP*TP*CP*GP*(6MA)P*AP*C)-3', 5'-D(*GP*TP*TP*CP*GP*(2PR)P*TP*GP*TP*C)-3', 5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE, ... | | 著者 | Pljevaljcic, G, Lenz, T, Scheidig, A.J, Weinhold, E. | | 登録日 | 2006-09-12 | | 公開日 | 2007-05-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | 2-Aminopurine Flipped into the Active Site of the Adenine-Specific DNA Methyltransferase M.TaqI: Crystal Structures and Time-Resolved Fluorescence
J.Am.Chem.Soc., 129, 2007
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6PSS
 | | Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5a) with TraR and mutant rpsT P2 promoter | | 分子名称: | DNA (85-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | | 登録日 | 2019-07-13 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
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6VOW
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7NXK
 | | Crystal structure of human Cdk12/Cyclin K in complex with the inhibitor BSJ-01-175 | | 分子名称: | (E)-N-[4-[(1R,3R)-3-[[5-chloranyl-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]cyclohexyl]oxyphenyl]-4-(dimethylamino)but-2-enamide, Cyclin-K, Cyclin-dependent kinase 12 | | 著者 | Anand, K, Dust, S, Kaltheuner, I.H, Geyer, M. | | 登録日 | 2021-03-18 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma.
Eur.J.Med.Chem., 221, 2021
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6PSQ
 | | Escherichia coli RNA polymerase closed complex (TRPc) with TraR and rpsT P2 promoter | | 分子名称: | CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | | 登録日 | 2019-07-13 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
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7P3Y
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7P3X
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7P3Z
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5ERX
 | | Crystal Structure of APO MenD from M. tuberculosis - I222 | | 分子名称: | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | | 著者 | Johnston, J.M, Jirgis, E.N.M, Bashiri, G, Bulloch, E.M.M, Baker, E.N. | | 登録日 | 2015-11-16 | | 公開日 | 2016-06-22 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.729 Å) | | 主引用文献 | Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms.
Structure, 24, 2016
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6VOF
 | | Chloroplast ATP synthase (O2, CF1FO) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ... | | 著者 | Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L. | | 登録日 | 2020-01-30 | | 公開日 | 2020-09-09 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (4.51 Å) | | 主引用文献 | Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
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7OTD
 | | Oxytocin NMR solution structure | | 分子名称: | AMINO GROUP, COPPER (II) ION, UNK-TYR-ILE-GLN-ASN-CYS-PRO-LEU-GLY | | 著者 | Shalev, D.E, Alshanski, I, Yitzchaik, S, Hurevich, M. | | 登録日 | 2021-06-10 | | 公開日 | 2021-10-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Determining the structure and binding mechanism of oxytocin-Cu 2+ complex using paramagnetic relaxation enhancement NMR analysis.
J.Biol.Inorg.Chem., 26, 2021
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7P9T
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7U6P
 | | Structure of an intellectual disability-associated ornithine decarboxylase variant G84R | | 分子名称: | Ornithine decarboxylase, PHOSPHATE ION | | 著者 | Zhou, X.E, Schultz, C.R, Powell, K.S, Henrickson, A, Lamp, J, Brunzelle, J.S, Demeler, B, Vega, I.E, Bachmann, A.S, Melcher, K. | | 登録日 | 2022-03-04 | | 公開日 | 2022-10-19 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure and Enzymatic Activity of an Intellectual Disability-Associated Ornithine Decarboxylase Variant, G84R.
Acs Omega, 7, 2022
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7RP0
 | | Structural Snapshots of Intermediates in the Gating of a K+ Channel | | 分子名称: | DIACYL GLYCEROL, KcsA Fab chain A, KcsA Fab chain B, ... | | 著者 | Reddi, R, Matulef, K, Riederer, E.A, Valiyaveetil, F.I. | | 登録日 | 2021-08-02 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Structures of Gating Intermediates in a K + channell.
J.Mol.Biol., 433, 2021
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7U6U
 | | Structure of an intellectual disability-associated ornithine decarboxylase variant G84R in complex with PLP | | 分子名称: | Ornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Zhou, X.E, Schultz, C.R, Powell, K.S, Henrickson, A, Lamp, J, Brunzelle, J.S, Demeler, B, Vega, I.E, Bachmann, A.S, Melcher, K. | | 登録日 | 2022-03-06 | | 公開日 | 2022-10-19 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure and Enzymatic Activity of an Intellectual Disability-Associated Ornithine Decarboxylase Variant, G84R.
Acs Omega, 7, 2022
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7PB5
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6Q2E
 | | Crystal structure of Methanobrevibacter smithii Dph2 bound to 5'-methylthioadenosine | | 分子名称: | 2-(3-amino-3-carboxypropyl)histidine synthase, 5'-DEOXY-5'-METHYLTHIOADENOSINE, CHLORIDE ION, ... | | 著者 | Fenwick, M.K, Dong, M, Lin, H, Ealick, S.E. | | 登録日 | 2019-08-07 | | 公開日 | 2019-10-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.768 Å) | | 主引用文献 | The Crystal Structure of Dph2 in Complex with Elongation Factor 2 Reveals the Structural Basis for the First Step of Diphthamide Biosynthesis.
Biochemistry, 58, 2019
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7PBA
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7PA4
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6HUC
 | | Yeast 20S proteasome with human beta2c (S171G) in complex with 18 | | 分子名称: | (2~{S})-~{N}-[2-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-2-oxidanylidene-ethyl]-2-[[(2~{S})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Huber, E.M, Groll, M. | | 登録日 | 2018-10-05 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
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5KC8
 | | Crystal structure of the amino-terminal domain (ATD) of iGluR Delta-2 (GluD2) | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Glutamate receptor ionotropic, ... | | 著者 | Elegheert, J, Clay, J.E, Siebold, C, Aricescu, A.R. | | 登録日 | 2016-06-05 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | | 主引用文献 | Structural basis for integration of GluD receptors within synaptic organizer complexes.
Science, 353, 2016
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7PBB
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