1APH
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![BU of 1aph by Molmil](/molmil-images/mine/1aph) | CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11 | 分子名称: | 1,2-DICHLOROETHANE, INSULIN A CHAIN (PH 7), INSULIN B CHAIN (PH 7) | 著者 | Gursky, O, Badger, J, Li, Y, Caspar, D.L.D. | 登録日 | 1992-10-30 | 公開日 | 1993-01-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Conformational changes in cubic insulin crystals in the pH range 7-11. Biophys.J., 63, 1992
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8GOU
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![BU of 8gou by Molmil](/molmil-images/mine/8gou) | Omicron BA.4/5 SARS-CoV-2 S in complex with TH003 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH003 Fab heavy chain, ... | 著者 | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | 登録日 | 2022-08-25 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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6TKI
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![BU of 6tki by Molmil](/molmil-images/mine/6tki) | Tsetse thrombin inhibitor in complex with human alpha-thrombin - tetragonal form at 12.7keV | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Thrombin heavy chain, ... | 著者 | Calisto, B.M, Ripoll-Rozada, J, de Sanctis, D, Pereira, P.J.B. | 登録日 | 2019-11-28 | 公開日 | 2020-11-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Sulfotyrosine-Mediated Recognition of Human Thrombin by a Tsetse Fly Anticoagulant Mimics Physiological Substrates. Cell Chem Biol, 28, 2021
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6J6Q
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![BU of 6j6q by Molmil](/molmil-images/mine/6j6q) | Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | 登録日 | 2019-01-15 | 公開日 | 2019-04-24 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
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6J6N
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![BU of 6j6n by Molmil](/molmil-images/mine/6j6n) | Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | 登録日 | 2019-01-15 | 公開日 | 2019-04-24 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | 主引用文献 | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
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1BPS
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![BU of 1bps by Molmil](/molmil-images/mine/1bps) | MINOR CONFORMER OF A BENZO[A]PYRENE DIOL EPOXIDE ADDUCT OF DA IN DUPLEX DNA | 分子名称: | 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, DNA (5'-D(*CP*TP*CP*GP*GP*GP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*CP*(BAP)AP*CP*GP*AP*G)-3') | 著者 | Schwartz, J.S, Rice, J.S, Luxon, B.A, Sayer, J.M, Xie, G, Yeh, H.J.C, Liu, X, Jerina, D.M, Gorenstein, D.G. | 登録日 | 1998-08-06 | 公開日 | 1998-08-19 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the minor conformer of a DNA duplex containing a dG mismatch opposite a benzo[a]pyrene diol epoxide/dA adduct: glycosidic rotation from syn to anti at the modified deoxyadenosine. Biochemistry, 36, 1997
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6TKL
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![BU of 6tkl by Molmil](/molmil-images/mine/6tkl) | Non-cleavable tsetse thrombin inhibitor in complex with human alpha-thrombin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Prothrombin, ... | 著者 | Calisto, B.M, Ripoll-Rozada, J, de Sanctis, D, Pereira, P.J.B. | 登録日 | 2019-11-28 | 公開日 | 2020-11-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Sulfotyrosine-Mediated Recognition of Human Thrombin by a Tsetse Fly Anticoagulant Mimics Physiological Substrates. Cell Chem Biol, 28, 2021
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5M8T
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![BU of 5m8t by Molmil](/molmil-images/mine/5m8t) | Crystal structure of human tyrosinase related protein 1 (T391V-R374S-Y362F) in complex with tropolone | 分子名称: | 2-HYDROXYCYCLOHEPTA-2,4,6-TRIEN-1-ONE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W. | 登録日 | 2016-10-29 | 公開日 | 2017-07-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis. Angew. Chem. Int. Ed. Engl., 56, 2017
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6T2Y
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![BU of 6t2y by Molmil](/molmil-images/mine/6t2y) | Streptavidin variants harbouring an artificial organocatalyst based cofactor | 分子名称: | 1,2-ETHANEDIOL, 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(1-pyridin-4-ylpiperidin-4-yl)pentanamide, Streptavidin | 著者 | Lechner, H, Hocker, B. | 登録日 | 2019-10-10 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | An Artificial Cofactor Catalyzing the Baylis-Hillman Reaction with Designed Streptavidin as Protein Host*. Chembiochem, 22, 2021
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7U36
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![BU of 7u36 by Molmil](/molmil-images/mine/7u36) | Crystal structure of human GSK3B in complex with ARN1484 | 分子名称: | (3S)-1-[(2-fluorophenoxy)acetyl]-N-(pyridin-2-yl)pyrrolidine-3-carboxamide, CHLORIDE ION, Glycogen synthase kinase-3 beta | 著者 | Tripathi, S.K, Balboni, B, Giabbai, B, Storici, P, Girotto, S, Cavalli, A. | 登録日 | 2022-02-25 | 公開日 | 2022-04-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Identification of Novel GSK-3 beta Hits Using Competitive Biophysical Assays. Int J Mol Sci, 23, 2022
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7U33
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![BU of 7u33 by Molmil](/molmil-images/mine/7u33) | Crystal structure of human GSK3B in complex with ARN9133 | 分子名称: | 3-[2-amino-5-(4-fluorophenyl)pyrimidin-4-yl]-N,N-dimethylazetidine-1-sulfonamide, CHLORIDE ION, Glycogen synthase kinase-3 beta | 著者 | Tripathi, S.K, Balboni, B, Giabbai, B, Storici, P, Girotto, S, Cavalli, A. | 登録日 | 2022-02-25 | 公開日 | 2022-04-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Identification of Novel GSK-3 beta Hits Using Competitive Biophysical Assays. Int J Mol Sci, 23, 2022
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7U2Z
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![BU of 7u2z by Molmil](/molmil-images/mine/7u2z) | Crystal structure of human GSK3B in complex with G12 | 分子名称: | (3R)-1-[3-(2-fluorophenyl)propanoyl]-N-(pyridin-2-yl)pyrrolidine-3-carboxamide, CHLORIDE ION, Glycogen synthase kinase-3 beta | 著者 | Tripathi, S.K, Balboni, B, Giabbai, B, Storici, P, Girotto, S, Cavalli, A. | 登録日 | 2022-02-25 | 公開日 | 2022-04-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Identification of Novel GSK-3 beta Hits Using Competitive Biophysical Assays. Int J Mol Sci, 23, 2022
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7U31
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![BU of 7u31 by Molmil](/molmil-images/mine/7u31) | Crystal structure of human GSK3B in complex with G5 | 分子名称: | 5-(4-fluorophenyl)-4-[1-(methanesulfonyl)azetidin-3-yl]pyrimidin-2-amine, CHLORIDE ION, Glycogen synthase kinase-3 beta | 著者 | Tripathi, S.K, Balboni, B, Giabbai, B, Storici, P, Girotto, S, Cavalli, A. | 登録日 | 2022-02-25 | 公開日 | 2022-04-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Identification of Novel GSK-3 beta Hits Using Competitive Biophysical Assays. Int J Mol Sci, 23, 2022
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7TQL
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![BU of 7tql by Molmil](/molmil-images/mine/7tql) | CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B. | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Lapointe, C.P, Grosely, R, Sokabe, M, Alvarado, C, Wang, J, Montabana, E, Villa, N, Shin, B, Dever, T, Fraser, C, Fernandez, I.S, Puglisi, J.D. | 登録日 | 2022-01-26 | 公開日 | 2022-04-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. Nature, 607, 2022
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6T8K
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![BU of 6t8k by Molmil](/molmil-images/mine/6t8k) | Crystal structure of Bacteroides thetaiotamicron EndoBT-3987 in complex with Man9GlcNAc product in P1 | 分子名称: | CALCIUM ION, Endo-beta-N-acetylglucosaminidase F1, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Trastoy, B, Du, J.J, Klontz, E.H, Cifuente, J.O, Sundberg, E.J, Guerin, M.E. | 登録日 | 2019-10-24 | 公開日 | 2020-02-26 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides. Nat Commun, 11, 2020
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5M8O
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![BU of 5m8o by Molmil](/molmil-images/mine/5m8o) | Crystal structure of human tyrosinase related protein 1 in complex with tropolone | 分子名称: | 2-HYDROXYCYCLOHEPTA-2,4,6-TRIEN-1-ONE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W. | 登録日 | 2016-10-29 | 公開日 | 2017-07-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis. Angew. Chem. Int. Ed. Engl., 56, 2017
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8TL8
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![BU of 8tl8 by Molmil](/molmil-images/mine/8tl8) | Structure of Orthoreovirus RNA Chaperone SigmaNS R6A mutant in complex with bile acid | 分子名称: | GLYCOCHOLIC ACID, Protein sigma-NS | 著者 | Prasad, B.V.V, Zhao, B, Hu, L, Neetu, N. | 登録日 | 2023-07-26 | 公開日 | 2024-03-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of orthoreovirus RNA chaperone sigma NS, a component of viral replication factories. Nat Commun, 15, 2024
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8TL1
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8TNN
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![BU of 8tnn by Molmil](/molmil-images/mine/8tnn) | Crystal structure of Epstein-Barr virus gH/gL/gp42 in complex with gp42 antibody A10 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, A10 heavy chain, A10 light chain, ... | 著者 | Bu, W, Kumar, A, Board, N, Kim, J, Dowdell, K, Zhang, S, Lei, Y, Hostal, A, Krogmann, T, Wang, Y, Pittaluga, S, Marcotrigiano, J, Cohen, J.I. | 登録日 | 2023-08-02 | 公開日 | 2024-03-27 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | 主引用文献 | Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells. Immunity, 57, 2024
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1BLF
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![BU of 1blf by Molmil](/molmil-images/mine/1blf) | STRUCTURE OF DIFERRIC BOVINE LACTOFERRIN AT 2.8 ANGSTROMS RESOLUTION | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | 著者 | Moore, S.A, Anderson, B.F, Groom, C.R, Haridas, M, Baker, E.N. | 登録日 | 1997-08-20 | 公開日 | 1997-12-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Three-dimensional structure of diferric bovine lactoferrin at 2.8 A resolution. J.Mol.Biol., 274, 1997
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8CUS
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8CUT
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![BU of 8cut by Molmil](/molmil-images/mine/8cut) | |
8CUX
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8TKA
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![BU of 8tka by Molmil](/molmil-images/mine/8tka) | |
8CUW
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![BU of 8cuw by Molmil](/molmil-images/mine/8cuw) | |