7U31

Crystal structure of human GSK3B in complex with G5

Summary for 7U31

• Entry DOI: 10.2210/pdb7u31/pdb
• Descriptor: Glycogen synthase kinase-3 beta, CHLORIDE ION, 5-(4-fluorophenyl)-4-[1-(methanesulfonyl)azetidin-3-yl]pyrimidin-2-amine, ... (4 entities in total)
• Functional Keywords: inhibitor, complex, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 80403.32

Authors

Tripathi, S.K.,Balboni, B.,Giabbai, B.,Storici, P.,Girotto, S.,Cavalli, A. (deposition date: 2022-02-25, release date: 2022-04-27, Last modification date: 2023-10-18)

• Primary citation: Balboni, B.,Tripathi, S.K.,Veronesi, M.,Russo, D.,Penna, I.,Giabbai, B.,Bandiera, T.,Storici, P.,Girotto, S.,Cavalli, A.; Identification of Novel GSK-3 beta Hits Using Competitive Biophysical Assays.; Int J Mol Sci, 23:-, 2022; PubMed: 35409221; DOI: 10.3390/ijms23073856

Experimental method

X-RAY DIFFRACTION (2.38 Å)