7U31

Crystal structure of human GSK3B in complex with G5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glycogen synthase kinase-3 beta	polymer	350	39843.8	2	UniProt (P49841) Pfam (PF00069)	Homo sapiens (human)	GSK-3 beta,Serine/threonine-protein kinase GSK3B
2	C, E (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
3	D, F (A, B)	5-(4-fluorophenyl)-4-[1-(methanesulfonyl)azetidin-3-yl]pyrimidin-2-amine	non-polymer		322.4	2	Chemie (L7I)
4	G, H (A, B)	water	water		18.0	63	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79687.7
Non-Polymers*	Number of molecules	4
	Total formula weight	715.6
All*	Total formula weight	80403.3

*Water molecules are not included.