7U33
Crystal structure of human GSK3B in complex with ARN9133
Summary for 7U33
| Entry DOI | 10.2210/pdb7u33/pdb |
| Descriptor | Glycogen synthase kinase-3 beta, CHLORIDE ION, 3-[2-amino-5-(4-fluorophenyl)pyrimidin-4-yl]-N,N-dimethylazetidine-1-sulfonamide, ... (4 entities in total) |
| Functional Keywords | inhibitor, complex, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 80635.55 |
| Authors | Tripathi, S.K.,Balboni, B.,Giabbai, B.,Storici, P.,Girotto, S.,Cavalli, A. (deposition date: 2022-02-25, release date: 2022-04-27, Last modification date: 2023-10-18) |
| Primary citation | Balboni, B.,Tripathi, S.K.,Veronesi, M.,Russo, D.,Penna, I.,Giabbai, B.,Bandiera, T.,Storici, P.,Girotto, S.,Cavalli, A. Identification of Novel GSK-3 beta Hits Using Competitive Biophysical Assays. Int J Mol Sci, 23:-, 2022 Cited by PubMed: 35409221DOI: 10.3390/ijms23073856 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report
