7U33

Crystal structure of human GSK3B in complex with ARN9133

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Glycogen synthase kinase-3 beta	polymer	351	39930.9	2	UniProt (P49841) Pfam (PF00069) In PDB	Homo sapiens (human)	GSK-3 beta,Serine/threonine-protein kinase GSK3B
2	A, B	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
3	A, B	3-[2-amino-5-(4-fluorophenyl)pyrimidin-4-yl]-N,N-dimethylazetidine-1-sulfonamide	non-polymer		351.4	2	Chemie (L7R)
4		water	water		18.0	67	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79861.8
Non-Polymers*	Number of molecules	4
	Total formula weight	773.7
All*	Total formula weight	80635.5

*Water molecules are not included.