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8CPD
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Cryo-EM structure of CRaf dimer with 14:3:3
分子名称: 14-3-3 protein zeta isoform X1, RAF proto-oncogene serine/threonine-protein kinase
著者Dedden, D, Graedler, U, Schwarz, D, Thomsen, M, Leuthner, B, Schneider, E, Nitsche, J.
登録日2023-03-02
公開日2024-02-21
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Cryo-EM Structures of CRAF 2 /14-3-3 2 and CRAF 2 /14-3-3 2 /MEK1 2 Complexes.
J.Mol.Biol., 436, 2024
8CHF
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BU of 8chf by Molmil
cryo-EM Structure of Craf:14-3-3:Mek1
分子名称: 14-3-3 protein zeta isoform X1, 2-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-3-(pyridin-4-yl)-1H-pyrazol-1-yl}ethanol, Dual specificity mitogen-activated protein kinase kinase 1, ...
著者Dedden, D, Ulrich, G.
登録日2023-02-07
公開日2024-02-21
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Cryo-EM Structures of CRAF 2 /14-3-3 2 and CRAF 2 /14-3-3 2 /MEK1 2 Complexes.
J.Mol.Biol., 436, 2024
8BZO
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BU of 8bzo by Molmil
Cryo-EM structure of CDK2-CyclinA in complex with p27 from the SCFSKP2 E3 ligase Complex
分子名称: Cyclin-A2, Cyclin-dependent kinase 2, Cyclin-dependent kinase inhibitor 1B
著者Rowland, R.J, Salamina, M, Endicott, J.A, Noble, M.E.
登録日2022-12-15
公開日2023-06-28
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.
Sci Rep, 13, 2023
8BYL
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BU of 8byl by Molmil
Cryo-EM structure of SKP1-SKP2-CKS1 from the SCFSKP2 E3 ligase complex
分子名称: Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, S-phase kinase-associated protein 1, ...
著者Rowland, R.J, Salamina, M, Endicott, J.A, Noble, M.E.M.
登録日2022-12-13
公開日2023-06-28
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.
Sci Rep, 13, 2023
1AFC
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BU of 1afc by Molmil
STRUCTURAL STUDIES OF THE BINDING OF THE ANTI-ULCER DRUG SUCROSE OCTASULFATE TO ACIDIC FIBROBLAST GROWTH FACTOR
分子名称: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ACIDIC FIBROBLAST GROWTH FACTOR
著者Zhu, X, Hsu, B.T, Rees, D.C.
登録日1993-07-13
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural studies of the binding of the anti-ulcer drug sucrose octasulfate to acidic fibroblast growth factor.
Structure, 1, 1993
7NIZ
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BU of 7niz by Molmil
Human 14-3-3 sigma in complex with human Estrogen Receptor alpha peptide and ligands Fusicoccin-A and WR-1065
分子名称: 14-3-3 protein sigma, Estrogen receptor, FUSICOCCIN, ...
著者Roversi, P, Falcicchio, M, Doveston, R.
登録日2021-02-14
公開日2021-12-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Cooperative stabilisation of 14-3-3 sigma protein-protein interactions via covalent protein modification.
Chem Sci, 12, 2021
1AJY
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BU of 1ajy by Molmil
STRUCTURE AND MOBILITY OF THE PUT3 DIMER: A DNA PINCER, NMR, 13 STRUCTURES
分子名称: PUT3, ZINC ION
著者Walters, K.J, Dayie, K.T, Reece, R.J, Ptashne, M, Wagner, G.
登録日1997-05-12
公開日1997-09-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and mobility of the PUT3 dimer.
Nat.Struct.Biol., 4, 1997
8CDN
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BU of 8cdn by Molmil
Crystal structure of human Brachyury in complex with a single T box binding element DNA
分子名称: DNA (5'-D(*AP*GP*GP*CP*TP*CP*AP*CP*AP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*TP*GP*TP*GP*AP*GP*CP*CP*T)-3'), T-box transcription factor T
著者Newman, J.A, Gavard, A.E, von Delft, F, Gileadi, O, Bountra, C.
登録日2023-01-31
公開日2023-03-22
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of human Brachyury in complex with a single T box binding element DNA
To Be Published
7NND
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BU of 7nnd by Molmil
Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide and fragment 09
分子名称: 14-3-3 protein sigma, 5-[1-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide, Amot-p130 phosphopeptide (pS175), ...
著者Centorrino, F, Ottmann, C.
登録日2021-02-24
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
7NMX
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Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide and fragment 12
分子名称: 14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), CALCIUM ION, ...
著者Centorrino, F, Ottmann, C.
登録日2021-02-23
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
7NPG
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BU of 7npg by Molmil
Crystal structure of 14-3-3 sigma in complex with 20mer Amot-p130 peptide and fragment 22
分子名称: 14-3-3 protein sigma, 5-[3-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide, Amot-p130 phosphopeptide (pS175), ...
著者Centorrino, F, Ottmann, C.
登録日2021-02-26
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
7NNE
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BU of 7nne by Molmil
Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide and fragment 22
分子名称: 14-3-3 protein sigma, 5-[3-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide, Amot-p130 phosphopeptide (pS175), ...
著者Centorrino, F, Ottmann, C.
登録日2021-02-24
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
7NMW
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BU of 7nmw by Molmil
Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide and fragment 40
分子名称: 14-3-3 protein sigma, 5-(2-azanylethyl)-4-phenyl-thiophene-2-carboximidamide, Amot-p130 phosphopeptide (pS175), ...
著者Centorrino, F, Ottmann, C.
登録日2021-02-23
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
7NMA
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BU of 7nma by Molmil
Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide
分子名称: 14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), CHLORIDE ION, ...
著者Centorrino, F, Ottmann, C.
登録日2021-02-23
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
7NPB
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BU of 7npb by Molmil
Crystal structure of 14-3-3 sigma in complex with 20mer Amot-p130 peptide and fragment 09
分子名称: 14-3-3 protein sigma, 5-[1-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide, Amot-p130 phosphopeptide (pS175), ...
著者Centorrino, F, Ottmann, C.
登録日2021-02-26
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
7NP2
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BU of 7np2 by Molmil
Crystal structure of 14-3-3 sigma in complex with 20mer Amot-p130 peptide
分子名称: 14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), CHLORIDE ION, ...
著者Centorrino, F, Ottmann, C.
登録日2021-02-26
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
7NN2
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BU of 7nn2 by Molmil
Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide and fragment 41
分子名称: 14-3-3 protein sigma, 7-(6-azanyl-5-methyl-pyridin-2-yl)-1-benzothiophene-2-carboximidamide, Amot-p130 phosphopeptide (pS175), ...
著者Centorrino, F, Ottmann, C.
登録日2021-02-24
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
1AD6
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BU of 1ad6 by Molmil
DOMAIN A OF HUMAN RETINOBLASTOMA TUMOR SUPPRESSOR
分子名称: RETINOBLASTOMA TUMOR SUPPRESSOR
著者Kim, H.Y, Cho, Y.
登録日1997-02-21
公開日1998-08-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural similarity between the pocket region of retinoblastoma tumour suppressor and the cyclin-box.
Nat.Struct.Biol., 4, 1997
7N16
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Structure of TAX-4_R421W apo closed state
分子名称: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, SODIUM ION
著者Zheng, X, Li, H, Hu, Z, Su, D, Yang, J.
登録日2021-05-27
公開日2022-03-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel.
Commun Biol, 5, 2022
7N17
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Structure of TAX-4_R421W apo open state
分子名称: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel
著者Zheng, X, Li, H, Hu, Z, Su, D, Yang, J.
登録日2021-05-27
公開日2022-03-16
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel.
Commun Biol, 5, 2022
7N15
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Structure of TAX-4_R421W w/cGMP open state
分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLIC GUANOSINE MONOPHOSPHATE, ...
著者Zheng, X, Li, H, Hu, Z, Su, D, Yang, J.
登録日2021-05-27
公開日2022-03-16
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel.
Commun Biol, 5, 2022
8CO6
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BU of 8co6 by Molmil
Subtomogram average of Immature Rotavirus TLP penton
分子名称: Inner capsid protein VP2, Intermediate capsid protein VP6, Outer capsid glycoprotein VP7, ...
著者Shah, P.N.M, Stuart, D.I.
登録日2023-02-27
公開日2023-05-10
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography.
Cell Host Microbe, 31, 2023
8C3C
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BU of 8c3c by Molmil
14-3-3 sigma with Pin1 binding site pS72 and bound Fusicoccin A
分子名称: 14-3-3 protein sigma, FUSICOCCIN, MAGNESIUM ION, ...
著者Verhoef, C.J, Cossar, P.
登録日2022-12-23
公開日2023-06-14
最終更新日2023-07-05
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Tracking the mechanism of covalent molecular glue stabilization using native mass spectrometry.
Chem Sci, 14, 2023
8C2G
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14-3-3 sigma with Pin1 binding site pS72 and covalently bound CV1040
分子名称: 14-3-3 protein sigma, 2-iodanyl-4-(2-phenylimidazol-1-yl)benzaldehyde, MAGNESIUM ION, ...
著者Verhoef, C.J, Cossar, P.
登録日2022-12-22
公開日2023-06-14
最終更新日2023-07-05
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Tracking the mechanism of covalent molecular glue stabilization using native mass spectrometry.
Chem Sci, 14, 2023
2JUL
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BU of 2jul by Molmil
NMR Structure of DREAM
分子名称: CALCIUM ION, Calsenilin
著者Ames, J.
登録日2007-08-30
公開日2008-04-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR structure of DREAM: Implications for Ca(2+)-dependent DNA binding and protein dimerization.
Biochemistry, 47, 2008

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件を2024-09-04に公開中

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