7NIZ

Human 14-3-3 sigma in complex with human Estrogen Receptor alpha peptide and ligands Fusicoccin-A and WR-1065

Summary for 7NIZ

• Entry DOI: 10.2210/pdb7niz/pdb
• Related: 4JDD
• Descriptor: 14-3-3 protein sigma, Estrogen receptor, FUSICOCCIN, ... (5 entities in total)
• Functional Keywords: signaling protein-peptide complex, fusicoccin-a, wr-1065, protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 32870.60

Authors

Roversi, P.,Falcicchio, M.,Doveston, R. (deposition date: 2021-02-14, release date: 2021-12-01, Last modification date: 2024-01-31)

• Primary citation: Falcicchio, M.,Ward, J.A.,Chothia, S.Y.,Basran, J.,Mohindra, A.,Macip, S.,Roversi, P.,Doveston, R.G.; Cooperative stabilisation of 14-3-3 sigma protein-protein interactions via covalent protein modification.; Chem Sci, 12:12985-12992, 2021; PubMed: 34745529; DOI: 10.1039/d1sc02120f

Experimental method

X-RAY DIFFRACTION (1.48 Å)