7NIZ
Human 14-3-3 sigma in complex with human Estrogen Receptor alpha peptide and ligands Fusicoccin-A and WR-1065
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 276 | 31184.7 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (B) | Estrogen receptor | polymer | 8 | 870.8 | 1 | UniProt (P03372) | Homo sapiens | ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1 |
| 3 | C (A) | FUSICOCCIN | non-polymer | 680.8 | 1 | Chemie (FSC) PubChem (46936214) PubChem (24124005) PubChem (44201245) PubChem (52940549) PubChem (57061783) PubChem (58892803) PubChem (143471529) PubChem (89167108) PubChem (89358776) PubChem (270757) PubChem (71308204) PubChem (447573) PubChem (89352860) PubChem (89424149) PubChem (91305733) PubChem (5381214) PubChem (124914704) PubChem (124914702) PubChem (125183286) PubChem (6437071) PubChem (134693211) PubChem (12309993) PubChem (138107212) PubChem (11534864) PubChem (124914703) PubChem (124914705) PubChem (146157920) PubChem (163008024) PubChem (134688043) PubChem (163008025) PubChem (163728719) | |||
| 4 | D (A) | WR-1065 | non-polymer | 134.2 | 1 | Chemie (UGH) PubChem (104807) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 123 | Chemie (HOH) |
Sequence modifications
A: 1 - 248 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Met -27 | - | initiating methionine |
| Ser -26 | - | expression tag |
| Tyr -25 | - | expression tag |
| Tyr -24 | - | expression tag |
| His -23 | - | expression tag |
| His -22 | - | expression tag |
| His -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| Asp -17 | - | expression tag |
| Tyr -16 | - | expression tag |
| Asp -15 | - | expression tag |
| Ile -14 | - | expression tag |
| Pro -13 | - | expression tag |
| Thr -12 | - | expression tag |
| Thr -11 | - | expression tag |
| Glu -10 | - | expression tag |
| Asn -9 | - | expression tag |
| Leu -8 | - | expression tag |
| Tyr -7 | - | expression tag |
| Phe -6 | - | expression tag |
| Gln -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32055.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 815.1 | |
| All* | Total formula weight | 32870.6 |
