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2C6O
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Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor
分子名称: CELL DIVISION PROTEIN KINASE 2, O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE
著者Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E.
登録日2005-11-10
公開日2005-12-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Triazolo[1,5-a]pyrimidines as novel CDK2 inhibitors: protein structure-guided design and SAR.
Bioorg. Med. Chem. Lett., 16, 2006
2CJQ
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Bovine viral diarrhea virus CP7-R12 RNA-dependent RNA polymerase
分子名称: RNA-DIRECTED RNA POLYMERASE
著者Choi, K.H, Gallei, A, Becher, P, Rossmann, M.G.
登録日2006-04-05
公開日2006-07-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Structure of Bovine Viral Diarrhea Virus RNA-Dependent RNA Polymerase and its Amino-Terminal Domain.
Structure, 14, 2006
2C6T
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Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor
分子名称: 4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2
著者Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E.
登録日2005-11-11
公開日2005-12-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Triazolo[1,5-A]Pyrimidines as Novel Cdk2 Inhibitors: Protein Structure-Guided Design and Sar.
Bioorg.Med.Chem.Lett., 16, 2006
2CCW
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Crystal structure of Azurin II at atomic resolution (1.13 angstrom)
分子名称: AZURIN II, COPPER (I) ION
著者Paraskevopoulos, K, Hough, M.A, Eady, R.R, Hasnain, S.S.
登録日2006-01-18
公開日2006-01-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Active Site Structures and the Redox Properties of Blue Copper Proteins: Atomic Resolution Structure of Azurin II and Electronic Structure Calculations of Azurin, Plastocyanin and Stellacyanin.
Dalton Trans., 25, 2006
2C7I
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Structure of protein Ta0514, putative lipoate protein ligase from T. acidophilum.
分子名称: PUTATIVE LIPOATE PROTEIN LIGASE
著者Mcmanus, E, Perham, R.N, Luisi, B.F.
登録日2005-11-24
公開日2005-12-15
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of a Putative Lipoate Protein Ligase from Thermoplasma Acidophilum and the Mechanism of Target Selection for Post-Translational Modification.
J.Mol.Biol., 356, 2006
2CFS
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crystal structure of human pyridoxal 5'-phosphate phosphatase
分子名称: MAGNESIUM ION, PYRIDOXAL PHOSPHATE PHOSPHATASE
著者Kang, B.S, Cho, H.J, Kim, K.J, Kwon, O.S.
登録日2006-02-23
公開日2007-02-27
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of Human Pyridoxal 5'-Phosphate Phosphatase
To be Published
2CM5
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crystal structure of the C2B domain of rabphilin
分子名称: CALCIUM ION, RABPHILIN-3A
著者Schlicker, C, Montaville, P, Sheldrick, G.M, Becker, S.
登録日2006-05-04
公開日2006-12-04
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献The C2A-C2B Linker Defines the High Affinity Ca2+ Binding Mode of Rabphilin-3A.
J.Biol.Chem., 282, 2007
2DAR
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Solution structure of first LIM domain of Enigma-like PDZ and LIM domains protein
分子名称: PDZ and LIM domain protein 5, ZINC ION
著者Niraula, T.N, Muto, Y, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-14
公開日2006-12-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of first LIM domain of Enigma-like PDZ and LIM domains protein
To be Published
2D57
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Double layered 2D crystal structure of AQUAPORIN-4 (AQP4M23) at 3.2 a resolution by electron crystallography
分子名称: Aquaporin-4
著者Hiroaki, Y, Tani, K, Kamegawa, A, Gyobu, N, Nishikawa, K, Suzuki, H, Walz, T, Sasaki, S, Mitsuoka, K, Kimura, K, Mizoguchi, A, Fujiyoshi, Y.
登録日2005-10-29
公開日2006-01-31
最終更新日2023-11-08
実験手法ELECTRON CRYSTALLOGRAPHY (3.2 Å)
主引用文献Implications of the Aquaporin-4 Structure on Array Formation and Cell Adhesion
J.Mol.Biol., 355, 2005
2D3D
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crystal structure of the RNA binding SAM domain of saccharomyces cerevisiae Vts1
分子名称: CALCIUM ION, Vts1 protein
著者Aviv, T, Amborski, A.N, Zhao, X.S, Kwan, J.J, Johnson, P.E, Sicheri, F, Donaldson, L.W.
登録日2005-09-27
公開日2006-02-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The NMR and X-ray Structures of the Saccharomyces cerevisiae Vts1 SAM Domain Define a Surface for the Recognition of RNA Hairpins
J.Mol.Biol., 356, 2006
8EAE
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Structure of Ternary Complex of cGAS with dsDNA and Bound 5-pppG(2,5)pI
分子名称: Cyclic GMP-AMP synthase, MAGNESIUM ION, Palindromic DNA18, ...
著者Wu, S, Sohn, J.
登録日2022-08-29
公開日2023-10-25
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
3TNQ
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Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein kinase, ...
著者Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S.
登録日2011-09-01
公開日2012-02-01
最終更新日2012-09-26
実験手法X-RAY DIFFRACTION (3.097 Å)
主引用文献Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
3O7L
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Crystal Structure of phospholamban (1-19):PKA C-subunit:AMP-PNP:Mg2+ complex
分子名称: Cardiac phospholamban, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
著者Cheng, C.Y, Taylor, S.S.
登録日2010-07-30
公開日2010-10-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Dynamics connect substrate recognition to catalysis in protein kinase A.
Nat.Chem.Biol., 6, 2010
3TNP
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Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit
著者Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S.
登録日2011-09-01
公開日2012-02-01
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
8EKC
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Escherichia coli 70S ribosome bound to thermorubin, deacylated P-site tRNAfMet and aminoacylated A-site Phe-tRNA
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Rybak, M.Y, Gagnon, M.G.
登録日2022-09-20
公開日2022-12-07
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin.
Nucleic Acids Res., 51, 2023
8EEB
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Cryo-EM structure of human ABCA7 in Digitonin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Phospholipid-transporting ATPase ABCA7, ...
著者Alam, A, Le, L.T.M, Thompson, J.R.
登録日2022-09-06
公開日2022-12-21
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
8EOP
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Cryo-EM Structure of Nanodisc reconstituted human ABCA7 EQ mutant in ATP bound closed state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Alam, A, Le, L.T.M, Thompson, J.R.
登録日2022-10-04
公開日2022-12-21
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
8EDW
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Cryo-EM Structure of human ABCA7 in BPL/Ch Nanodiscs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Alam, A, Le, L.T.M, Thompson, J.R.
登録日2022-09-06
公開日2022-12-21
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
8EE6
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Cryo-EM Structure of human ABCA7 in PE/Ch nanodiscs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Phospholipid-transporting ATPase ABCA7, ...
著者Alam, A, Le, L.T.M, Thompson, J.R.
登録日2022-09-06
公開日2022-12-21
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
8EIU
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E. coli 70S ribosome with A-loop mutations U2554C and U2555C
分子名称: 16S rRNA, 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ...
著者Nissley, A.J, Penev, P.I, Watson, Z.L, Banfield, J.F, Cate, J.H.D.
登録日2022-09-15
公開日2023-02-01
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.24 Å)
主引用文献Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome.
Nucleic Acids Res., 51, 2023
8EXH
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Agrobacterium tumefaciens Tpilus
分子名称: (14S,17R)-20-amino-17-hydroxy-11,17-dioxo-12,16,18-trioxa-17lambda~5~-phosphaicosan-14-yl tetradecanoate, Protein virB2
著者Beltran, L.C, Egelman, E.H.
登録日2022-10-25
公開日2023-03-22
最終更新日2024-09-25
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Archaeal DNA-import apparatus is homologous to bacterial conjugation machinery
Nat Commun, 14, 2023
8F4J
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RT XFEL structure of Photosystem II 4000 microseconds after the third illumination at 2.00 Angstrom resolution
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Bhowmick, A, Hussein, R, Bogacz, I, Simon, P.S, Ibrahim, M, Chatterjee, R, Doyle, M.D, Cheah, M.H, Fransson, T, Chernev, P, Kim, I.-S, Makita, H, Dasgupta, M, Kaminsky, C.J, Zhang, M, Gatcke, J, Haupt, S, Nangca, I.I, Keable, S.M, Aydin, O, Tono, K, Owada, S, Gee, L.B, Fuller, F.D, Batyuk, A, Alonso-Mori, R, Holton, J.M, Paley, D.W, Moriarty, N.W, Mamedov, F, Adams, P.D, Brewster, A.S, Dobbek, H, Sauter, N.K, Bergmann, U, Zouni, A, Messinger, J, Kern, J, Yano, J, Yachandra, V.K.
登録日2022-11-10
公開日2023-03-22
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural evidence for intermediates during O 2 formation in photosystem II.
Nature, 617, 2023
8F4F
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RT XFEL structure of Photosystem II 500 microseconds after the third illumination at 2.03 Angstrom resolution
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Bhowmick, A, Hussein, R, Bogacz, I, Simon, P.S, Ibrahim, M, Chatterjee, R, Doyle, M.D, Cheah, M.H, Fransson, T, Chernev, P, Kim, I.-S, Makita, H, Dasgupta, M, Kaminsky, C.J, Zhang, M, Gatcke, J, Haupt, S, Nangca, I.I, Keable, S.M, Aydin, O, Tono, K, Owada, S, Gee, L.B, Fuller, F.D, Batyuk, A, Alonso-Mori, R, Holton, J.M, Paley, D.W, Moriarty, N.W, Mamedov, F, Adams, P.D, Brewster, A.S, Dobbek, H, Sauter, N.K, Bergmann, U, Zouni, A, Messinger, J, Kern, J, Yano, J, Yachandra, V.K.
登録日2022-11-10
公開日2023-03-22
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structural evidence for intermediates during O 2 formation in photosystem II.
Nature, 617, 2023
8EZ5
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RT XFEL structure of the two-flash state of Photosystem II (2F, S3-rich) at 2.09 Angstrom resolution
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Bhowmick, A, Hussein, R, Bogacz, I, Simon, P.S, Ibrahim, M, Chatterjee, R, Doyle, M.D, Cheah, M.H, Fransson, T, Chernev, P, Kim, I.-S, Makita, H, Dasgupta, M, Kaminsky, C.J, Zhang, M, Gatcke, J, Haupt, S, Nangca, I.I, Keable, S.M, Aydin, O, Tono, K, Owada, S, Gee, L.B, Fuller, F.D, Batyuk, A, Alonso-Mori, R, Holton, J.M, Paley, D.W, Moriarty, N.W, Mamedov, F, Adams, P.D, Brewster, A.S, Dobbek, H, Sauter, N.K, Bergmann, U, Zouni, A, Messinger, J, Kern, J, Yano, J, Yachandra, V.K.
登録日2022-10-31
公開日2023-03-22
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural evidence for intermediates during O 2 formation in photosystem II.
Nature, 617, 2023
8F4I
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RT XFEL structure of Photosystem II 2000 microseconds after the third illumination at 2.00 Angstrom resolution
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Bhowmick, A, Hussein, R, Bogacz, I, Simon, P.S, Ibrahim, M, Chatterjee, R, Doyle, M.D, Cheah, M.H, Fransson, T, Chernev, P, Kim, I.-S, Makita, H, Dasgupta, M, Kaminsky, C.J, Zhang, M, Gatcke, J, Haupt, S, Nangca, I.I, Keable, S.M, Aydin, O, Tono, K, Owada, S, Gee, L.B, Fuller, F.D, Batyuk, A, Alonso-Mori, R, Holton, J.M, Paley, D.W, Moriarty, N.W, Mamedov, F, Adams, P.D, Brewster, A.S, Dobbek, H, Sauter, N.K, Bergmann, U, Zouni, A, Messinger, J, Kern, J, Yano, J, Yachandra, V.K.
登録日2022-11-10
公開日2023-03-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural evidence for intermediates during O 2 formation in photosystem II.
Nature, 617, 2023

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