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4IZY
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Crystal structure of JNK1 in complex with JIP1 peptide and 4-{4-[4-(4-Methanesulfonyl-piperidin-1-yl)-indol-1-yl]-pyrimidin-2-ylamino}-cyclohexan
分子名称: C-Jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 8, trans-4-[(4-{4-[4-(methylsulfonyl)piperidin-1-yl]-1H-indol-1-yl}pyrimidin-2-yl)amino]cyclohexanol
著者Kuglstatter, A, Shao, A.
登録日2013-01-30
公開日2013-12-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Development of indole/indazole-aminopyrimidines as inhibitors of c-Jun N-terminal kinase (JNK): optimization for JNK potency and physicochemical properties.
Bioorg.Med.Chem.Lett., 23, 2013
2LSK
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BU of 2lsk by Molmil
C-terminal domain of human REV1 in complex with DNA-polymerase H (eta)
分子名称: DNA polymerase eta, DNA repair protein REV1
著者Pozhidaeva, A, Pustovalova, Y, Bezsonova, I, Korzhnev, D.
登録日2012-05-01
公開日2012-06-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure and dynamics of the C-terminal domain from human Rev1 and its complex with Rev1 interacting region of DNA polymerase eta.
Biochemistry, 51, 2012
2MOX
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solution structure of tandem SH3 domain of Sorbin and SH3 domain-containing protein 1
分子名称: Sorbin and SH3 domain-containing protein 1
著者Zhao, D, Wang, C, Zhang, J, Wu, J, Shi, Y, Zhang, Z, Gong, Q.
登録日2014-05-07
公開日2014-05-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
1W6X
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SH3 domain of p40phox, component of the NADPH oxidase
分子名称: NEUTROPHIL CYTOSOL FACTOR 4
著者Massenet, C, Chenavas, S, Cohen-Addad, C, Dagher, M.-C, Brandolin, G, Pebay-Peyroula, E, Fieschi, F.
登録日2004-08-24
公開日2005-01-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Effects of P47Phox C-Terminus Phosphorylation on Binding Interactions with P40Phox and P67Phox: Structural and Functional Comparison of P40Phox P67Phox SH3 Domains
J.Biol.Chem., 280, 2005
6XFS
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BU of 6xfs by Molmil
Class C beta-lactamase from Escherichia coli in complex with Tazobactam
分子名称: 1,2-ETHANEDIOL, Beta-lactamase, DI(HYDROXYETHYL)ETHER, ...
著者Chang, C, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-06-16
公開日2020-07-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Class C beta-lactamase from Escherichia coli in complex with Tazobactam
To Be Published
1EV4
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RAT GLUTATHIONE S-TRANSFERASE A1-1: MUTANT W21F/F220Y WITH GSO3 BOUND
分子名称: GLUTATHIONE S-TRANSFERASE A1-1, GLUTATHIONE SULFONIC ACID, SULFATE ION
著者Adman, E.T, Le Trong, I, Stenkamp, R.E, Nieslanik, B.S, Dietze, E.C, Tai, G, Ibarra, C, Atkins, W.M.
登録日2000-04-19
公開日2001-02-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Localization of the C-terminus of rat glutathione S-transferase A1-1: crystal structure of mutants W21F and W21F/F220Y.
Proteins, 42, 2001
6XVM
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Crystal structure of c-Src SH3 domain without ATCUN motif: monomer 2
分子名称: GLYCEROL, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A, Plaza-Garrido, M.
登録日2020-01-22
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XVN
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Crystal structure of c-Src SH3 domain without ATCUN motif: monomer 1
分子名称: Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A, Plaza-Garrido, M.
登録日2020-01-22
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
1ESH
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THE SOLUTION STRUCTURE OF THE STEM LOOP C 5'AUA3' TRILOOP OF BROME MOSAIC VIRUS (+) STRAND RNA
分子名称: RNA (5'-R(*GP*GP*UP*GP*CP*AP*UP*AP*GP*CP*AP*CP*C)-3')
著者Kim, C.-H, Kao, C.C, Tinoco Jr, I.
登録日2000-04-10
公開日2000-04-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献RNA motifs that determine specificity between a viral replicase and its promoter.
Nat.Struct.Biol., 7, 2000
6XVO
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Crystal structure of the intertwined dimer of the c-Src SH3 domain without ATCUN motif
分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
著者Camara-Artigas, A, Plaza-Garrido, M.
登録日2020-01-22
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XX4
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Crystal structure of the c-Src SH3 domain H122R-Q128E mutant in complex with Ni(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin
分子名称: Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A.
登録日2020-01-26
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XX3
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Crystal structure of the c-Src SH3 domain H122R-Q128E mutant in complex with Cu(II) at pH 6.5 co-crystallized with methyl beta-cyclodextrin
分子名称: COPPER (II) ION, Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A.
登録日2020-01-26
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
4W90
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Crystal structure of Bacillus subtilis cyclic-di-AMP riboswitch ydaO
分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A, ...
著者Jones, C.P, Ferre-D'Amare, A.R.
登録日2014-08-26
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.118 Å)
主引用文献Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA.
Embo J., 33, 2014
8C6J
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Human spliceosomal PM5 C* complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
著者Dybkov, O, Kastner, B, Luehrmann, R.
登録日2023-01-12
公開日2023-07-12
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins.
Sci Adv, 9, 2023
1MQK
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Crystal structure of the unliganded Fv-fragment of the anti-cytochrome C oxidase antibody 7E2
分子名称: antibody 7E2 FV fragment, heavy chain, light chain
著者Essen, L.-O, Harrenga, A, Ostermeier, C, Michel, H.
登録日2002-09-16
公開日2003-04-01
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献1.3 A X-ray structure of an antibody Fv fragment used for induced membrane-protein crystallization.
Acta Crystallogr.,Sect.D, 59, 2003
1N1I
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The structure of MSP-1(19) from Plasmodium knowlesi
分子名称: HISTIDINE, IMIDAZOLE, Merozoite surface protein-1
著者Garman, S.C, Simcoke, W.N, Stowers, A.W, Garboczi, D.N.
登録日2002-10-17
公開日2003-02-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the C-terminal domains of merozoite surface protein-1 from Plasmodium knowlesi reveals a novel histidine binding site
J.Biol.Chem., 278, 2003
3VRC
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BU of 3vrc by Molmil
Crystal structure of cytochrome c' from Thermochromatium tepidum
分子名称: CADMIUM ION, CHLORIDE ION, Cytochrome c', ...
著者Hirano, Y, Kimura, Y, Suzuki, H, Miki, K, Wang, Z.-Y.
登録日2012-04-09
公開日2012-09-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Structure Analysis and Comparative Characterization of the Cytochrome c' and Flavocytochrome c from Thermophilic Purple Photosynthetic Bacterium Thermochromatium tepidum
Biochemistry, 51, 2012
3VRD
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BU of 3vrd by Molmil
Crystal structure of flavocytochrome c from Thermochromatium tepidum
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Flavocytochrome c flavin subunit, Flavocytochrome c heme subunit, ...
著者Hirano, Y, Kimura, Y, Suzuki, H, Miki, K, Wang, Z.-Y.
登録日2012-04-09
公開日2012-09-12
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure Analysis and Comparative Characterization of the Cytochrome c' and Flavocytochrome c from Thermophilic Purple Photosynthetic Bacterium Thermochromatium tepidum
Biochemistry, 51, 2012
5VP9
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Crystal structure of HCV NS3/4A protease in complex with AM-07, an analogue of 5172-mcP1P3
分子名称: NS4A cofactor -- NS3 protein chimera, SULFATE ION, ZINC ION, ...
著者Matthew, A.N, Schiffer, C.A.
登録日2017-05-04
公開日2017-06-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.859 Å)
主引用文献Hepatitis C Virus NS3/4A Protease Inhibitors Incorporating Flexible P2 Quinoxalines Target Drug Resistant Viral Variants.
J. Med. Chem., 60, 2017
3D1I
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Structure of the Thioalkalivibrio nitratireducens cytochrome c nitrite reductase in a complex with nitrite
分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, CALCIUM ION, Eight-heme nitrite reductase, ...
著者Polyakov, K.M, Boyko, K.M, Slutsky, A, Tikhonova, T.V, Antipov, A.N, Zvyagilskaya, R.A, Popov, A.N, Lamzin, V.S, Bourenkov, G.P, Popov, V.O.
登録日2008-05-06
公開日2009-05-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High-resolution structural analysis of a novel octaheme cytochrome c nitrite reductase from the haloalkaliphilic bacterium Thioalkalivibrio nitratireducens
J.Mol.Biol., 389, 2009
5WSP
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Crystal structure of DNA3 duplex
分子名称: DNA (5'-D(*GP*GP*TP*CP*GP*TP*CP*C)-3'), STRONTIUM ION
著者Gan, J.H, Liu, H.H.
登録日2016-12-08
公開日2017-02-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.502 Å)
主引用文献Flexibility and stabilization of HgII-mediated C:T and T:T base pairs in DNA duplex
Nucleic Acids Res., 45, 2017
5WSR
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Crystal structure of T-Hg-T pair containing DNA duplex
分子名称: DNA (5'-D(*GP*GP*TP*CP*GP*TP*CP*C)-3'), MERCURY (II) ION
著者Gan, J.H, Liu, H.H.
登録日2016-12-08
公開日2017-02-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Flexibility and stabilization of HgII-mediated C:T and T:T base pairs in DNA duplex
Nucleic Acids Res., 45, 2017
3D1D
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Hexagonal crystal structure of Tas3 C-terminal alpha motif
分子名称: RNA-induced transcriptional silencing complex protein tas3
著者Li, H, Patel, D.J.
登録日2008-05-05
公開日2009-04-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
3D1B
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Tetragonal crystal structure of Tas3 C-terminal alpha motif
分子名称: RNA-induced transcriptional silencing complex protein tas3
著者Li, H, Patel, D.J.
登録日2008-05-05
公開日2009-04-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
3DOB
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Peptide-binding domain of Heat shock 70 kDa protein F44E5.5 from C.elegans.
分子名称: BETA-MERCAPTOETHANOL, Heat shock 70 kDa protein F44E5.5
著者Osipiuk, J, Hatzos, C, Gu, M, Zhang, R, Voisine, C, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-07-03
公開日2008-07-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献X-ray crystal structure of Peptide-binding domain of Heat shock 70 kDa protein F44E5.5 from C.elegans.
To be Published

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件を2024-07-17に公開中

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