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9KPL
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BU of 9kpl by Molmil
Crystal structure of T. rubripes Mincle with glucose
分子名称: C-type lectin domain-containing protein, CALCIUM ION, alpha-D-glucopyranose, ...
著者Ito, T, Nagae, M, Yamasaki, S.
登録日2024-11-23
公開日2025-04-02
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Phylogenetic and structural insights into the origin of C-type lectin Mincle in vertebrates.
Immunogenetics, 77, 2025
8PE0
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BU of 8pe0 by Molmil
X-ray structure of the Thermus thermophilus K167L mutant of the PilF-GSPIIB domain in the c-di-GMP bound state
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ACETATE ION, SULFATE ION, ...
著者Neissner, K, Woehnert, J.
登録日2023-06-13
公開日2024-06-26
最終更新日2025-01-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis for high-affinity c-di-GMP binding to the GSPII-B domain of the traffic ATPase PilF from Thermus thermophilus.
J.Biol.Chem., 301, 2024
8PDK
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BU of 8pdk by Molmil
X-ray structure of the Thermus thermophilus PilF-GSPIIB domain in the c-di-GMP bound state
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ACETATE ION, SULFATE ION, ...
著者Neissner, K, Woehnert, J.
登録日2023-06-12
公開日2024-06-26
最終更新日2025-01-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structural basis for high-affinity c-di-GMP binding to the GSPII-B domain of the traffic ATPase PilF from Thermus thermophilus.
J.Biol.Chem., 301, 2024
8PFA
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BU of 8pfa by Molmil
X-ray structure of the Thermus thermophilus K167R mutant of the PilF-GSPIIB domain in the c-di-GMP bound state
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ACETATE ION, SULFATE ION, ...
著者Neissner, K, Woehnert, J.
登録日2023-06-15
公開日2024-06-26
最終更新日2025-01-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structural basis for high-affinity c-di-GMP binding to the GSPII-B domain of the traffic ATPase PilF from Thermus thermophilus.
J.Biol.Chem., 301, 2024
7KWM
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BU of 7kwm by Molmil
CtBP1 (28-375) L182F/V185T - AMP
分子名称: ADENOSINE MONOPHOSPHATE, C-terminal-binding protein 1, CALCIUM ION
著者Royer, W.E, Del Campo, M.
登録日2020-12-01
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP).
J.Biol.Chem., 296, 2021
2LSK
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BU of 2lsk by Molmil
C-terminal domain of human REV1 in complex with DNA-polymerase H (eta)
分子名称: DNA polymerase eta, DNA repair protein REV1
著者Pozhidaeva, A, Pustovalova, Y, Bezsonova, I, Korzhnev, D.
登録日2012-05-01
公開日2012-06-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure and dynamics of the C-terminal domain from human Rev1 and its complex with Rev1 interacting region of DNA polymerase eta.
Biochemistry, 51, 2012
3EFK
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BU of 3efk by Molmil
Structure of c-Met with pyrimidone inhibitor 50
分子名称: 5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-2-[(4-fluorophenyl)amino]-3-methylpyrimidin-4(3H)-one, Hepatocyte growth factor receptor
著者Bellon, S.F, D'Angelo, N, Whittington, D, Dussault, I.
登録日2008-09-09
公開日2008-10-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Design, synthesis, and biological evaluation of potent c-Met inhibitors.
J.Med.Chem., 51, 2008
3EFJ
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BU of 3efj by Molmil
Structure of c-Met with pyrimidone inhibitor 7
分子名称: 2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-3-methylpyrimidin-4(3H)-one, Hepatocyte growth factor receptor
著者D'Angelo, N, Bellon, S, Whittington, D.
登録日2008-09-09
公開日2008-10-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Design, synthesis, and biological evaluation of potent c-Met inhibitors.
J.Med.Chem., 51, 2008
4IZY
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BU of 4izy by Molmil
Crystal structure of JNK1 in complex with JIP1 peptide and 4-{4-[4-(4-Methanesulfonyl-piperidin-1-yl)-indol-1-yl]-pyrimidin-2-ylamino}-cyclohexan
分子名称: C-Jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 8, trans-4-[(4-{4-[4-(methylsulfonyl)piperidin-1-yl]-1H-indol-1-yl}pyrimidin-2-yl)amino]cyclohexanol
著者Kuglstatter, A, Shao, A.
登録日2013-01-30
公開日2013-12-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Development of indole/indazole-aminopyrimidines as inhibitors of c-Jun N-terminal kinase (JNK): optimization for JNK potency and physicochemical properties.
Bioorg.Med.Chem.Lett., 23, 2013
4TRK
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BU of 4trk by Molmil
Structure of C. elegans HIM-3
分子名称: C. elegans HIM-3
著者Rosenberg, S.C, Corbett, K.D.
登録日2014-06-17
公開日2014-11-19
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.751 Å)
主引用文献The Chromosome Axis Controls Meiotic Events through a Hierarchical Assembly of HORMA Domain Proteins.
Dev.Cell, 31, 2014
4TZJ
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BU of 4tzj by Molmil
Structure of C. elegans HIM-3 bound to HTP-3 closure motif-4
分子名称: C. elegans HIM-3 and HTP-3
著者Rosenberg, S.C, Corbett, K.D.
登録日2014-07-10
公開日2014-11-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.851 Å)
主引用文献The Chromosome Axis Controls Meiotic Events through a Hierarchical Assembly of HORMA Domain Proteins.
Dev.Cell, 31, 2014
5UTS
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BU of 5uts by Molmil
Carbon Sulfoxide lyase, Egt2 in the Ergothioneine biosynthesis pathway
分子名称: C-S Lyase Egt2, FORMIC ACID
著者Irani, S, Zhang, Y.
登録日2017-02-15
公開日2018-02-21
最終更新日2025-04-02
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Snapshots of C-S Cleavage in Egt2 Reveals Substrate Specificity and Reaction Mechanism.
Cell Chem Biol, 25, 2018
2XR4
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BU of 2xr4 by Molmil
C-terminal domain of BC2L-C Lectin from Burkholderia cenocepacia
分子名称: LECTIN, SULFATE ION
著者Sulak, O, Cioci, G, Lameignere, E, Delia, M, Wimmerova, M, Imberty, A.
登録日2010-09-09
公開日2011-08-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Burkholderia Cenocepacia Bc2L-C is a Super Lectin with Dual Specificity and Proinflammatory Activity.
Plos Pathog., 7, 2011
2JDQ
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BU of 2jdq by Molmil
C-terminal domain of influenza A virus polymerase PB2 subunit in complex with human importin alpha5
分子名称: IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC PROTEIN 2
著者Tarendeau, F, Guilligay, D, Mas, P, Boulo, S, Baudin, F, Ruigrok, R.W.H, Hart, D.J, Cusack, S.
登録日2007-01-11
公開日2007-02-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and Nuclear Import Function of the C- Terminal Domain of Influenza Virus Polymerase Pb2 Subunit
Nat.Struct.Mol.Biol., 14, 2007
4TZL
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BU of 4tzl by Molmil
Structure of C. elegans HTP-2 bound to HIM-3 closure motif, P21 form
分子名称: C. elegans HIM-3 closure motif, Protein HTP-2
著者Rosenberg, S.C, Corbett, K.D.
登録日2014-07-10
公開日2014-11-19
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.537 Å)
主引用文献The Chromosome Axis Controls Meiotic Events through a Hierarchical Assembly of HORMA Domain Proteins.
Dev.Cell, 31, 2014
4TZO
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BU of 4tzo by Molmil
Structure of C. elegans HTP-1 bound to HIM-3 closure motif
分子名称: C. elegans HIM-3 closure motif, Protein HTP-1
著者Rosenberg, S.C, Corbett, K.D.
登録日2014-07-10
公開日2014-11-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Chromosome Axis Controls Meiotic Events through a Hierarchical Assembly of HORMA Domain Proteins.
Dev.Cell, 31, 2014
7L4V
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BU of 7l4v by Molmil
C-terminal bZIP domain of human C/EBPbeta Bound to DNA with Consensus Recognition with GT Mismatch
分子名称: 1,2-ETHANEDIOL, CCAAT/enhancer-binding protein beta, DNA Strand 1, ...
著者Horton, J.R, Cheng, X.
登録日2020-12-21
公開日2021-11-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Preferential CEBP binding to T:G mismatches and increased C-to-T human somatic mutations.
Nucleic Acids Res., 49, 2021
6B6X
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BU of 6b6x by Molmil
Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase, dithionite-reduced (protein batch 2), canonical C-cluster
分子名称: CHLORIDE ION, Carbon monoxide dehydrogenase, FE(4)-NI(1)-S(4) CLUSTER, ...
著者Wittenborn, E.C, Drennan, C.L.
登録日2017-10-03
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase.
Elife, 7, 2018
6B6Y
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BU of 6b6y by Molmil
Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase, dithionite-reduced then oxygen-exposed (protein batch 2), oxidized C-cluster
分子名称: Carbon monoxide dehydrogenase, FE2/S2 (INORGANIC) CLUSTER, Fe(4)-Ni(1)-S(4) cluster, ...
著者Wittenborn, E.C, Drennan, C.L.
登録日2017-10-03
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase.
Elife, 7, 2018
6B6V
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BU of 6b6v by Molmil
Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase, as-isolated (protein batch 1), canonical C-cluster
分子名称: Carbon monoxide dehydrogenase, FE(4)-NI(1)-S(4) CLUSTER, FE2/S2 (INORGANIC) CLUSTER, ...
著者Wittenborn, E.C, Drennan, C.L.
登録日2017-10-03
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase.
Elife, 7, 2018
3PYY
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BU of 3pyy by Molmil
Discovery and Characterization of a Cell-Permeable, Small-molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site
分子名称: (5R)-5-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]imidazolidine-2,4-dione, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, GLYCEROL, ...
著者Yang, J, Campobasso, N, Biju, M.P, Fisher, K, Pan, X.Q, Cottom, J, Galbraith, S, Ho, T, Zhang, H, Hong, X, Ward, P, Hofmann, G, Siegfried, B.
登録日2010-12-13
公開日2011-03-09
最終更新日2025-05-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site.
Chem.Biol., 18, 2011
1RMJ
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BU of 1rmj by Molmil
C-terminal domain of insulin-like growth factor (IGF) binding protein-6: structure and interaction with IGF-II
分子名称: Insulin-like growth factor binding protein 6
著者Headey, S.J, Keizer, D.W, Yao, S, Brasier, G, Kantharidis, P, Bach, L.A, Norton, R.S.
登録日2003-11-28
公開日2004-09-14
最終更新日2024-11-20
実験手法SOLUTION NMR
主引用文献C-terminal domain of insulin-like growth factor (IGF) binding protein-6: structure and interaction with IGF-II.
Mol.Endocrinol., 18, 2004
6B6W
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BU of 6b6w by Molmil
Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase, as-isolated (protein batch 2), oxidized C-cluster
分子名称: CHLORIDE ION, Carbon monoxide dehydrogenase, FE(4)-NI(1)-S(4) CLUSTER, ...
著者Wittenborn, E.C, Drennan, C.L.
登録日2017-10-03
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase.
Elife, 7, 2018
4TZS
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BU of 4tzs by Molmil
Structure of C. elegans HTP-2 bound to HIM-3 closure motif, P212121 form
分子名称: C. elegans HIM-3 closure motif, Protein HTP-2
著者Rosenberg, S.C, Corbett, K.D.
登録日2014-07-10
公開日2014-11-19
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The Chromosome Axis Controls Meiotic Events through a Hierarchical Assembly of HORMA Domain Proteins.
Dev.Cell, 31, 2014
1GUA
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BU of 1gua by Molmil
HUMAN RAP1A, RESIDUES 1-167, DOUBLE MUTANT (E30D,K31E) COMPLEXED WITH GPPNHP AND THE RAS-BINDING-DOMAIN OF HUMAN C-RAF1, RESIDUES 51-131
分子名称: C-RAF1, CALCIUM ION, MAGNESIUM ION, ...
著者Nassar, N, Wittinghofer, A.
登録日1996-06-18
公開日1997-01-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Ras/Rap effector specificity determined by charge reversal.
Nat.Struct.Biol., 3, 1996

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