PDB: 72150 件ウェブページステータス検索Chemie searchBIRD

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3P0P	Human Tankyrase 2 - Catalytic PARP domain in complex with an inhibitor 分子名称: 2-[4-(4-fluorophenyl)piperazin-1-yl]-6-methylpyrimidin-4(3H)-one, SULFATE ION, Tankyrase-2, ... 著者 Karlberg, T, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kotenyova, T, Kouznetsova, E, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schutz, P, Sehic, A, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC) 登録日 2010-09-29 公開日 2010-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors Nat.Biotechnol., 30, 2012
3P0Q	Human Tankyrase 2 - Catalytic PARP domain in complex with an inhibitor 分子名称: N-[2-(4-chlorophenyl)ethyl]-6-methyl[1,2,4]triazolo[4,3-b]pyridazin-8-amine, SODIUM ION, SULFATE ION, ... 著者 Karlberg, T, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kotenyova, T, Kouznetsova, E, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schutz, P, Sehic, A, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC) 登録日 2010-09-29 公開日 2010-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors Nat.Biotechnol., 30, 2012
3MHJ	Human tankyrase 2 - catalytic PARP domain in complex with 1-methyl-3-(trifluoromethyl)-5h-benzo[c][1,8]naphtyridine-6-one 分子名称: 1-methyl-3-(trifluoromethyl)benzo[c][1,8]naphthyridin-6(5H)-one, SULFATE ION, Tankyrase-2, ... 著者 Karlberg, T, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kotenyova, T, Markova, N, Moche, M, Nordlund, P, Nyman, T, Persson, C, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) 登録日 2010-04-08 公開日 2010-05-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors Nat.Biotechnol., 30, 2012
8GF8	Cryo-EM structure of human TRPV1 in cNW11 nanodisc and soybean lipids 分子名称: (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, ... 著者 Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. 登録日 2023-03-07 公開日 2023-05-10 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Human TRPV1 structure and inhibition by the analgesic SB-366791. Nat Commun, 14, 2023
8GF9	Cryo-EM structure of human TRPV1 in cNW11 nanodisc and POPC:POPE:POPG lipids 分子名称: (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, ... 著者 Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. 登録日 2023-03-07 公開日 2023-05-10 実験手法 ELECTRON MICROSCOPY (2.58 Å) 主引用文献 Human TRPV1 structure and inhibition by the analgesic SB-366791. Nat Commun, 14, 2023
5EB5	The crystal structure of almond HNL, PaHNL5 V317A, in complex with benzyl alcohol 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Pavkov-Keller, T, Steinkellner, G, Gruber, K. 登録日 2015-10-17 公開日 2016-04-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structures of almond hydroxynitrile lyase isoenzyme 5 provide a rationale for the lack of oxidoreductase activity in flavin dependent HNLs. J.Biotechnol., 235, 2016
8HBS	Crystal of rAlfNmt 分子名称: Glycylpeptide N-tetradecanoyltransferase 著者 Wang, Y, Wang, S. 登録日 2022-10-30 公開日 2023-03-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 N -Myristoyltransferase, a Potential Antifungal Candidate Drug-Target for Aspergillus flavus. Microbiol Spectr, 11, 2023
3OEQ	Crystal structure of trimeric frataxin from the yeast Saccharomyces cerevisiae, with full length n-terminus 分子名称: Frataxin homolog, mitochondrial 著者 Soderberg, C.A.G, Rajan, S, Gakh, O, Ta, C, Isaya, G, Al-Karadaghi, S. 登録日 2010-08-13 公開日 2011-08-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Oligomerization Propensity and Flexibility of Yeast Frataxin Studied by X-ray Crystallography and Small-Angle X-ray Scattering. J.Mol.Biol., 414, 2011
3OER	Crystal structure of trimeric frataxin from the yeast saccharomyces cerevisiae, complexed with cobalt 分子名称: COBALT (II) ION, Frataxin homolog, mitochondrial 著者 Soderberg, C.A.G, Rajan, S, Gakh, O, Ta, C, Isaya, G, Al-Karadaghi, S. 登録日 2010-08-13 公開日 2011-08-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Oligomerization Propensity and Flexibility of Yeast Frataxin Studied by X-ray Crystallography and Small-Angle X-ray Scattering. J.Mol.Biol., 414, 2011
1Z6C	Solution structure of an EGF pair (EGF34) from vitamin K-dependent protein S 分子名称: CALCIUM ION, Vitamin K-dependent protein S 著者 Drakenberg, T, Ghasriani, H, Thulin, E, Thamlitz, A.M, Muranyi, A, Annila, A, Stenflo, J. 登録日 2005-03-22 公開日 2005-06-21 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the Ca(2+)-Binding EGF3-4 Pair from Vitamin K-Dependent Protein S: Identification of an Unusual Fold in EGF3. Biochemistry, 44, 2005
7QHH	Desensitized state of GluA1/2 AMPA receptor in complex with TARP-gamma 8 (TMD-LBD) 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, GLUTAMIC ACID, ... 著者 Herguedas, B, Kohegyi, B, Dohrke, J.N, Watson, J.F, Zhang, D, Ho, H, Shaikh, S, Lape, R, Krieger, J.M, Greger, I.H. 登録日 2021-12-12 公開日 2022-02-23 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Mechanisms underlying TARP modulation of the GluA1/2-gamma 8 AMPA receptor. Nat Commun, 13, 2022
7QHB	Active state of GluA1/2 in complex with TARP gamma 8, L-glutamate and CTZ 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, CYCLOTHIAZIDE, ... 著者 Herguedas, B, Kohegyi, B, Zhang, D, Greger, I.H. 登録日 2021-12-11 公開日 2022-02-23 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Mechanisms underlying TARP modulation of the GluA1/2-gamma 8 AMPA receptor. Nat Commun, 13, 2022
7PGP	The core structure of human neurofibromin isoform 2 分子名称: Neurofibromin 著者 Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. 登録日 2021-08-15 公開日 2022-08-24 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The structure of neurofibromin isoform 2 reveals different functional states. Nature, 599, 2021
7PPR	The structure of UDP-glucose pyrophosphorylase from Aspergillus fumigatus 分子名称: CHLORIDE ION, SULFATE ION, UTP--glucose-1-phosphate uridylyltransferase 著者 Morton, S, Raimi, O.G, Yan, K, van Aalten, D.M.F. 登録日 2021-09-14 公開日 2022-09-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Genetic and structural validation of UDP-glucose pyrophosphorylase as a novel antifungal target against Aspergillus fumigatus To Be Published
7PGQ	GAP-SecPH region of human neurofibromin isoform 2 in closed conformation. 分子名称: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Neurofibromin, ZINC ION 著者 Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. 登録日 2021-08-15 公開日 2022-10-26 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 The structure of neurofibromin isoform 2 reveals different functional states. Nature, 599, 2021
7RST	The Crystal Structure of Recombinant Chloroperoxidase Expressed in Aspergillus niger 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chloroperoxidase, ... 著者 Tang, X, Venkadesh, S, Zhou, J, Rosen, B, Wang, X. 登録日 2021-08-11 公開日 2022-08-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 The Crystal Structure of Recombinant Chloroperoxidase Expressed in Aspergillus niger To Be Published
8GDO	Crystal structure of DH1010 Fab 分子名称: DH1010 Fab Heavy Chain, DH1010 Fab Light chain 著者 Lindenberger, J, Acharya, P. 登録日 2023-03-06 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of DH1010 Fab To Be Published
7R5M	Core-binding domain of fungal E3-binding domain bound to the pyruvate dehydrogenase E2 core 分子名称: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, Pyruvate dehydrogenase X component 著者 Forsberg, B.O. 登録日 2022-02-11 公開日 2023-01-18 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 The structure and evolutionary diversity of the fungal E3-binding protein. Commun Biol, 6, 2023
5BU9	Crystal structure of Beta-N-acetylhexosaminidase from Beutenbergia cavernae DSM 12333 分子名称: Beta-N-acetylhexosaminidase, GLYCEROL 著者 Chang, C, Tan, K, Li, H, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2015-06-03 公開日 2015-06-17 実験手法 X-RAY DIFFRACTION (2.255 Å) 主引用文献 Crystal structure of Beta-N-acetylhexosaminidase from Beutenbergia cavernae DSM 12333 To Be Published
3MSX	Crystal structure of RhoA.GDP.MgF3 in complex with GAP domain of ArhGAP20 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho GTPase-activating protein 20, ... 著者 Utepbergenov, D, Cooper, D.R, Derewenda, U, Derewenda, Z.S. 登録日 2010-04-29 公開日 2011-03-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Mechanism of molecular specificity of RhoGAP domains towards small GTPases of RhoA family. To be Published
8U1S	A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-393 heavy chain, ... 著者 Ferguson, J.A, Raghavan, S.S.R, Ward, A.B. 登録日 2023-09-02 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface To Be Published
8U1C	A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-400 heavy chain, ... 著者 Ferguson, J.A, Oeverdieck, S, Ward, A.B. 登録日 2023-08-31 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface To Be Published
8U1Q	A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-2D10 heavy chain, ... 著者 Ferguson, J.A, Oeverdieck, S, Ward, A.B. 登録日 2023-09-01 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.36 Å) 主引用文献 A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface To Be Published
6PU1	Cysteine stabilized hexameric HIV-1 CA in complex with SEC24C peptide 分子名称: CHLORIDE ION, Gag polyprotein, IODIDE ION, ... 著者 Lindenberger, J.J, Kvaratskhelia, M. 登録日 2019-07-16 公開日 2021-01-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Cysteine stabilized hexameric HIV-1 CA in complex with SEC24C peptide To Be Published
7JGX	Solution NMR structure of neuroVAL, a derived peptide from wasp 分子名称: neuroVAL derived peptide ILE-PHE-TRP-LEU-PHE-ARG-GLY-LYS-ALA-ASP-VAL-ALA-LEU-NH2 著者 Muller, J.A.I, Craik, D.J, Koehbach, J. 登録日 2020-07-20 公開日 2020-12-16 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Antimicrobial and Anticancer Properties of Synthetic Peptides Derived from the Wasp Parachartergus fraternus. Chembiochem, 22, 2021

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