PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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3G4S	Co-crystal structure of Tiamulin bound to the large ribosomal subunit 分子名称: 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L10e, ... 著者 Gurel, G, Blaha, G, Moore, P.B, Steitz, T.A. 登録日 2009-02-04 公開日 2009-04-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome. J.Mol.Biol., 389, 2009
2OC9	Crystal structure of human purine nucleoside phosphorylase mutant H257G with Imm-H 分子名称: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, PHOSPHATE ION, Purine nucleoside phosphorylase 著者 Rinaldo-Matthis, A, Almo, S.C, Schramm, V.L. 登録日 2006-12-20 公開日 2007-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase Biochemistry, 46, 2007
4ODD	Crystal structure of a dog lipocalin allergen 分子名称: LIPOCALIN ALLERGEN 著者 Niemi, M.H, Rouvinen, J. 登録日 2014-01-10 公開日 2014-06-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural aspects of dog allergies: The crystal structure of a dog dander allergen Can f 4. Mol.Immunol., 61, 2014
3G30	CTX-M-9 class A beta-lactamase complexed with compound 3 (G30) 分子名称: (1S,2R)-2-[(2,5-difluorophenyl)carbamoyl]cyclopropanecarboxylic acid, Beta-lactamase CTX-M-9a 著者 Chen, Y, Shoichet, B.K. 登録日 2009-02-01 公開日 2009-03-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular docking and ligand specificity in fragment-based inhibitor discovery Nat.Chem.Biol., 5, 2009
2OD9	Structural Basis for Nicotinamide Inhibition and Base Exchange in Sir2 Enzymes 分子名称: 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, H4 peptide, NAD-dependent deacetylase HST2, ... 著者 Marmorstein, R, Sanders, B.D. 登録日 2006-12-21 公開日 2007-02-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes. Mol.Cell, 25, 2007
2ITC	Potassium Channel KcsA-Fab complex in Sodium Chloride 分子名称: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, SODIUM ION, ... 著者 Lockless, S.W, Zhou, M, MacKinnon, R. 登録日 2006-10-19 公開日 2007-05-15 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel. Plos Biol., 5, 2007
3PCO	crystal structure of E. coli phenylalanine-tRNA synthetase complexed with phenylalanine and AMP 分子名称: ADENOSINE MONOPHOSPHATE, PHENYLALANINE, Phenylalanyl-tRNA synthetase, ... 著者 Mermershtain, I, Finarov, I, Klipcan, L, Kessler, N, Rozenberg, H, Safro, M.G. 登録日 2010-10-21 公開日 2011-03-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Idiosyncrasy and identity in the prokaryotic phe-system: crystal structure of E. coli phenylalanyl-tRNA synthetase complexed with phenylalanine and AMP. Protein Sci., 20, 2011
3PC7	X-ray crystal structure of the DNA ligase III-alpha BRCT domain. 分子名称: DNA ligase 3 著者 Cuneo, M.J, Krahn, J.M, London, R.E. 登録日 2010-10-21 公開日 2011-06-15 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The structural basis for partitioning of the XRCC1/DNA ligase III-{alpha} BRCT-mediated dimer complexes. Nucleic Acids Res., 39, 2011
3G80	Nodamura virus protein b2, RNA-binding domain 分子名称: Protein B2 著者 Korber, S, Shaik Syed Ali, P, Chen, J.C. 登録日 2009-02-11 公開日 2010-01-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the RNA-Binding Domain of Nodamura Virus Protein B2, a Suppressor of RNA Interference. Biochemistry, 48, 2009
3PC6	X-ray crystal structure of the second XRCC1 BRCT domain. 分子名称: DNA repair protein XRCC1 著者 Cuneo, M.J, Krahn, J.M, London, R.E. 登録日 2010-10-21 公開日 2011-06-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The structural basis for partitioning of the XRCC1/DNA ligase III-{alpha} BRCT-mediated dimer complexes. Nucleic Acids Res., 39, 2011
4H2X	Crystal structure of engineered Bradyrhizobium japonicum glycine:[carrier protein] ligase complexed with carrier protein from Agrobacterium tumefaciens and an analogue of glycyl adenylate 分子名称: 4'-PHOSPHOPANTETHEINE, 5'-O-(glycylsulfamoyl)adenosine, Amino acid--[acyl-carrier-protein] ligase 1, ... 著者 Luic, M, Weygand-Durasevic, I, Ivic, N, Mocibob, M. 登録日 2012-09-13 公開日 2013-03-06 最終更新日 2017-08-23 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Adaptation of aminoacyl-tRNA synthetase catalytic core to carrier protein aminoacylation. Structure, 21, 2013
2O8V	PAPS reductase in a covalent complex with thioredoxin C35A 分子名称: Phosphoadenosine phosphosulfate reductase, Thioredoxin 1 著者 Chartron, J, Shiau, C, Stout, C.D, Carroll, K.S. 登録日 2006-12-12 公開日 2007-03-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 3'-Phosphoadenosine-5'-phosphosulfate Reductase in Complex with Thioredoxin: A Structural Snapshot in the Catalytic Cycle. Biochemistry, 46, 2007
4ONA	Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1517 分子名称: 5-amino-1-tert-butyl-3-(7-ethoxyquinolin-3-yl)-1H-pyrazole-4-carboxamide, Calmodulin-domain protein kinase 1 著者 Merritt, E.A. 登録日 2014-01-28 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Potent and selective inhibitors of CDPK1 from T. gondii and C. parvum based on a 5-aminopyrazole-4-carboxamide scaffold. ACS Med Chem Lett, 5, 2014
3PC4	Full length structure of cystathionine beta-synthase from Drosophila in complex with serine 分子名称: (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine, CG1753, isoform A, ... 著者 Koutmos, M, Smith, J.L. 登録日 2010-10-21 公開日 2010-12-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine {beta}-synthase. Proc.Natl.Acad.Sci.USA, 107, 2010
2O95	Crystal Structure of the Metal-Free Dimeric Human Mov34 MPN domain (residues 1-186) 分子名称: 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 26S proteasome non-ATPase regulatory subunit 7, DODECAETHYLENE GLYCOL, ... 著者 Sanches, M, Alves, B.S.C, Zanchin, N.I.T, Guimaraes, B.G. 登録日 2006-12-13 公開日 2007-07-17 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The Crystal Structure of the Human Mov34 MPN Domain Reveals a Metal-free Dimer J.Mol.Biol., 370, 2007
4ONR	Crystal structure of Borrelia burgdorferi decorin-binding protein DbpA 分子名称: DECORIN-BINDING PROTEIN DbpA, NICKEL (II) ION 著者 Tomchick, D.R, Deka, R.K, Blevins, J.S. 登録日 2014-01-28 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Identification of Lysine Residues in the Borrelia burgdorferi DbpA Adhesin Required for Murine Infection. Infect.Immun., 82, 2014
3PDJ	Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase 1 (11b-HSD1) in Complex with 4,4-Disubstituted Cyclohexylbenzamide Inhibitor 分子名称: Corticosteroid 11-beta-dehydrogenase isozyme 1, N-[trans-4-(3-amino-3-oxopropyl)-4-phenylcyclohexyl]-N-cyclopropyl-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Wang, Z, Sudom, A, Walker, N.P. 登録日 2010-10-22 公開日 2011-10-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Synthesis and Optimization of Novel 4,4-Disubstituted Cyclohexylbenzamide Derivatives as Potent 11beta-HSD1 Inhibitors Bioorg.Med.Chem.Lett., 21, 2011
3GAI	Structure of a F112A variant PduO-type ATP:corrinoid adenosyltransferase from Lactobacillus reuteri complexed with cobalamin and ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, COBALAMIN, ... 著者 St Maurice, M, Mera, P.E, Escalante-Semerena, J.C, Rayment, I. 登録日 2009-02-17 公開日 2009-07-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Residue Phe112 of the human-type corrinoid adenosyltransferase (PduO) enzyme of Lactobacillus reuteri is critical to the formation of the four-coordinate Co(II) corrinoid substrate and to the activity of the enzyme. Biochemistry, 48, 2009
2OKA	Crystal structure of Q9HYQ7_PSEAE from Pseudomonas aeruginosa. Northeast Structural Genomics Consortium target PaR82 分子名称: Hypothetical protein 著者 Benach, J, Neely, H, Seetharaman, J, Chen, X.C, Fang, Y, Cunningham, K, Owens, L, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2007-01-16 公開日 2007-01-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of Q9HYQ7_PSEAE from Pseudomonas aeruginosa To be Published
4WM9	Acinetobacter baumanii OXA-24 complex with Avibactam 分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1,2-ETHANEDIOL, Beta-lactamase, ... 著者 Mangani, S, Benvenuti, M, Docquier, J.-D. 登録日 2014-10-08 公開日 2014-12-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular Basis of Selective Inhibition and Slow Reversibility of Avibactam against Class D Carbapenemases: A Structure-Guided Study of OXA-24 and OXA-48. Acs Chem.Biol., 10, 2015
4JKX	Crystal structure Mistletoe Lectin I from Viscum album in complex with kinetin at 2.35 A resolution. 分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Prokofev, I.I, Lashkov, A.A, Gabdoulkhakov, A.G, Meyer, A, Barciszewski, J, Betzel, C, Mikhailov, A.M. 登録日 2013-03-12 公開日 2014-05-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structure Mistletoe Lectin I from Viscum album in complex with kinetin at 2.35 A resolution. To be Published
4JKE	Open and closed forms of T1789P human PRP8 RNase H-like domain with bound Mg ion 分子名称: MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8 著者 Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M. 登録日 2013-03-09 公開日 2013-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
4JKO	Crystal structure of a catalytic mutant of Axe2 (Axe2_S15A), an acetylxylan esterase from Geobacillus stearothermophilus 分子名称: Acetyl xylan esterase, GLYCEROL, PHOSPHATE ION 著者 Azulay, D, Lansky, S, Alalouf, O, Solomon, V, Alhassid, A, Belrahli, H, Govada, L, Chayan, N.E, Shoham, Y, Shoham, G. 登録日 2013-03-11 公開日 2014-02-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A unique octameric structure of Axe2, an intracellular acetyl-xylooligosaccharide esterase from Geobacillus stearothermophilus. Acta Crystallogr.,Sect.D, 70, 2014
4JLG	SETD7 in complex with inhibitor (R)-PFI-2 and S-adenosyl-methionine 分子名称: 8-fluoro-N-{(2R)-1-oxo-1-(pyrrolidin-1-yl)-3-[3-(trifluoromethyl)phenyl]propan-2-yl}-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide, Histone-lysine N-methyltransferase SETD7, S-ADENOSYLMETHIONINE, ... 著者 Dong, A, Wu, H, Zeng, H, El Bakkouri, M, Barsyte, D, Vedadi, M, Tatlock, J, Owen, D, Bunnage, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) 登録日 2013-03-12 公開日 2013-04-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.896 Å) 主引用文献 (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells. Proc.Natl.Acad.Sci.USA, 111, 2014
3PDC	Crystal structure of hydrolase domain of human soluble epoxide hydrolase complexed with a benzoxazole inhibitor 分子名称: Epoxide hydrolase 2, N-(5-chloro-1,3-benzoxazol-2-yl)-2-cyclopentylacetamide 著者 Kurumbail, R.G, Williams, J.M. 登録日 2010-10-22 公開日 2011-04-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Discovery of potent inhibitors of soluble epoxide hydrolase by combinatorial library design and structure-based virtual screening. J.Med.Chem., 54, 2011

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