PDB: 45953 件ウェブページステータス検索Chemie searchBIRD

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8G10	Structure of Ternary Complex of cGAS with dsDNA and Bound ITP and GTP 分子名称: Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-02-01 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
6ZNS	Crystal Structure of DUF1998 helicase MrfA 分子名称: Uncharacterized ATP-dependent helicase YprA, ZINC ION 著者 Roske, J.J, Liu, S, Loll, B, Neu, U, Wahl, M.C. 登録日 2020-07-06 公開日 2020-11-25 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.32 Å) 主引用文献 A skipping rope translocation mechanism in a widespread family of DNA repair helicases. Nucleic Acids Res., 49, 2021
4L5S	p202 HIN1 in complex with 12-mer dsDNA 分子名称: 12-mer DNA, Interferon-activable protein 202, SULFATE ION 著者 Yin, Q, Tian, Y, Wu, H. 登録日 2013-06-11 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation. Cell Rep, 4, 2013
7LRM	Structure of HIV-1 Reverse Transcriptase in complex with DNA, dCTP, and CA(2+) ion 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA/RNA (38-MER), ... 著者 Hoang, A, Ruiz, F.X, Arnold, E. 登録日 2021-02-16 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing. Drug Discov Today, 27, 2022
7LRY	Structure of HIV-1 Reverse Transcriptase in complex with DNA, (-)FTC-TP, and CA(2+) ion 分子名称: AMMONIUM ION, CALCIUM ION, DNA/RNA (38-MER), ... 著者 Hoang, A, Ruiz, F.X, Arnold, E. 登録日 2021-02-17 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing. Drug Discov Today, 27, 2022
7LRI	Structure of HIV-1 Reverse Transcriptase in complex with DNA, dTTP, and CA(2+) ion 分子名称: CALCIUM ION, DNA/RNA (38-MER), GLYCEROL, ... 著者 Hoang, A, Ruiz, F.X, Arnold, E. 登録日 2021-02-16 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing. Drug Discov Today, 27, 2022
7LRX	Structure of HIV-1 Reverse Transcriptase in complex with DNA, L-dCTP, and CA(2+) ion 分子名称: 4-amino-1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-L-erythro-pentofuranosyl}pyrimidin-2(1H)-one, AMMONIUM ION, CALCIUM ION, ... 著者 Hoang, A, Ruiz, F.X, Arnold, E. 登録日 2021-02-17 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing. Drug Discov Today, 27, 2022
7LSK	Structure of HIV-1 Reverse Transcriptase in complex with DNA, L-dTTP, and CA(2+) ion 分子名称: 1-{2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-L-erythro-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione, AMMONIUM ION, CALCIUM ION, ... 著者 Hoang, A, Ruiz, F.X, Arnold, E. 登録日 2021-02-18 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing. Drug Discov Today, 27, 2022
1AKO	EXONUCLEASE III FROM ESCHERICHIA COLI 分子名称: EXONUCLEASE III 著者 Mol, C.D, Kuo, C.-F, Thayer, M.M, Cunningham, R.P, Tainer, J.A. 登録日 1997-05-26 公開日 1997-08-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure and function of the multifunctional DNA-repair enzyme exonuclease III. Nature, 374, 1995
3CLO	Crystal structure of putative transcriptional regulator containing a LuxR DNA binding domain (NP_811094.1) from Bacteroides thetaiotaomicron VPI-5482 at 2.04 A resolution 分子名称: CHLORIDE ION, GLYCEROL, SODIUM ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2008-03-19 公開日 2008-04-01 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Crystal structure of putative transcriptional regulator containing a LuxR DNA binding domain (NP_811094.1) from Bacteroides thetaiotaomicron VPI-5482 at 2.04 A resolution To be published
2EDU	Solution structure of RSGI RUH-070, a C-terminal domain of kinesin-like protein KIF22 from human cDNA 分子名称: Kinesin-like protein KIF22 著者 Abe, T, Hirota, H, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-02-15 公開日 2007-08-21 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of RSGI RUH-070, a C-terminal domain of kinesin-like protein KIF22 from human cDNA To be Published
4E7I	PFV intasome freeze-trapped prior to 3'-processing, Mn-bound form (UI-Mn) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*AP*AP*T)-3'), ... 著者 Hare, S, Cherepanov, P. 登録日 2012-03-17 公開日 2012-05-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5301 Å) 主引用文献 3'-Processing and strand transfer catalysed by retroviral integrase in crystallo. Embo J., 31, 2012
6C66	CRISPR RNA-guided surveillance complex, pre-nicking 分子名称: CRISPR-associated helicase, Cas3 family, CRISPR-associated protein, ... 著者 Xiao, Y, Luo, M, Liao, M, Ke, A. 登録日 2018-01-17 公開日 2018-06-27 最終更新日 2023-11-29 実験手法 ELECTRON MICROSCOPY (3.66 Å) 主引用文献 Structure basis for RNA-guided DNA degradation by Cascade and Cas3. Science, 361, 2018
7CSW	Pseudomonas aeruginosa antitoxin HigA with pa2440 promoter 分子名称: HTH cro/C1-type domain-containing protein, pa2440 著者 Song, Y.J, Luo, G.H, Bao, R. 登録日 2020-08-17 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Pseudomonas aeruginosa antitoxin HigA functions as a diverse regulatory factor by recognizing specific pseudopalindromic DNA motifs. Environ.Microbiol., 23, 2021
7CLG	Crystal structure of the ATP-dependent restriction endonuclease SauUSI 分子名称: Putative helicase, SULFATE ION 著者 Saikrishnan, K, Tumuluri, V.S. 登録日 2020-07-21 公開日 2021-01-20 最終更新日 2021-08-04 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Mechanism of DNA cleavage by the endonuclease SauUSI: a major barrier to horizontal gene transfer and antibiotic resistance in Staphylococcus aureus. Nucleic Acids Res., 49, 2021
7MTT	Crystal structure of colibactin self-resistance protein ClbS in complex with two molecules of CHES 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Colibactin self-protection protein ClbS 著者 Tripathi, P, Bruner, S.D. 登録日 2021-05-13 公開日 2021-05-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural Basis for the Interactions of the Colibactin Resistance Gene Product ClbS with DNA. Biochemistry, 60, 2021
5JJ3	Refined Structure of the Mature Virion Conformation of P22 Portal Protein 分子名称: Portal protein 著者 Lokareddy, R.K, Sankhala, R.S, Cingolani, G. 登録日 2016-04-22 公開日 2017-02-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (7 Å) 主引用文献 Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation. Nat Commun, 8, 2017
2K9I	NMR structure of plasmid copy control protein ORF56 from sulfolobus islandicus 分子名称: Uncharacterized protein ORF56 著者 Weininger, U, Balbach, J. 登録日 2008-10-15 公開日 2009-10-20 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structure-Based Stability Analysis of an Extremely Stable Dimeric DNA Binding Protein from Sulfolobus islandicus Biochemistry, 48, 2009
5UIY	Structure of Bromodomain from human BAZ1A 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bromodomain adjacent to zinc finger domain protein 1A 著者 Oppikofer, M, Sudhamsu, J. 登録日 2017-01-16 公開日 2017-07-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.687 Å) 主引用文献 Non-canonical reader modules of BAZ1A promote recovery from DNA damage. Nat Commun, 8, 2017
5D5Z	Structure of Chaetomium thermophilum Skn7 coiled-coil domain, crystal form II 分子名称: Putative transcription factor 著者 Neudegger, T, Verghese, J, Hayer-Hartl, M, Bracher, A, Hartl, F.U. 登録日 2015-08-11 公開日 2015-12-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
5D5Y	Structure of Chaetomium thermophilum Skn7 coiled-coil domain, crystal form I 分子名称: Putative transcription factor 著者 Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. 登録日 2015-08-11 公開日 2015-12-30 最終更新日 2016-02-10 実験手法 X-RAY DIFFRACTION (1.03 Å) 主引用文献 Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
2B1D	5'-D(*GP*CP*AP*GP*AP*CP*GP*TP*CP*TP*GP*C)-3' Methionine Repressor binding site 分子名称: 5'-D(*GP*CP*AP*GP*AP*CP*GP*TP*CP*TP*GP*C)-3', COBALT HEXAMMINE(III), MAGNESIUM ION 著者 Berman, H.M, Locasale, J.W, Napoli, A.A. 登録日 2005-09-15 公開日 2005-09-27 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Signatures of protein-DNA recognition in free DNA binding sites. J.Mol.Biol., 386, 2009
1IQT	Solution structure of the C-terminal RNA-binding domain of heterogeneous nuclear ribonucleoprotein D0 (AUF1) 分子名称: heterogeneous nuclear ribonucleoprotein D0 著者 Katahira, M, Miyanoiri, Y, Enokizono, Y, Matsuda, G, Nagata, T, Ishikawa, F, Uesugi, S. 登録日 2001-08-01 公開日 2002-08-07 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Structure of the C-terminal RNA-binding domain of hnRNP D0 (AUF1), its interactions with RNA and DNA, and change in backbone dynamics upon complex formation with DNA. J.Mol.Biol., 311, 2001
3HEF	Crystal structure of the bacteriophage Sf6 terminase small subunit 分子名称: Gene 1 protein 著者 Zhao, H, Tang, L. 登録日 2009-05-08 公開日 2010-02-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of the DNA-recognition component of the bacterial virus Sf6 genome-packaging machine Proc.Natl.Acad.Sci.USA, 107, 2010
2F4Q	Crystal Structure of Deinococcus radiodurans topoisomerase IB 分子名称: type I topoisomerase, putative 著者 Patel, A, Shuman, S, Mondragon, A. 登録日 2005-11-23 公開日 2005-12-27 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of a bacterial type IB DNA topoisomerase reveals a preassembled active site in the absence of DNA. J.Biol.Chem., 281, 2006

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