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7YIG
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Human KCNH5 pre-open state 2
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIE
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BU of 7yie by Molmil
Human KCNH5-closed state 2
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIH
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BU of 7yih by Molmil
Human KCNH5 open state
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIF
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BU of 7yif by Molmil
Human KCNH5 pre-open state 1
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7MIX
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BU of 7mix by Molmil
Human N-type voltage-gated calcium channel Cav2.2 in the presence of ziconotide at 3.0 Angstrom resolution
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, N, Gao, S, Yao, X.
登録日2021-04-18
公開日2021-07-07
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of human Ca v 2.2 channel blocked by the painkiller ziconotide.
Nature, 596, 2021
7MIY
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BU of 7miy by Molmil
Human N-type voltage-gated calcium channel Cav2.2 at 3.1 Angstrom resolution
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, N, Gao, S, Yao, X.
登録日2021-04-18
公開日2021-07-07
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of human Ca v 2.2 channel blocked by the painkiller ziconotide.
Nature, 596, 2021
7MIO
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BU of 7mio by Molmil
Mouse TRPV3 in cNW11 nanodiscs, open state at 42 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7X6I
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BU of 7x6i by Molmil
Cryo-EM structure of the human TRPC5 ion channel in complex with G alpha i3 subunits, class1
分子名称: (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ...
著者Won, J, Jeong, H, Lee, H.H.
登録日2022-03-07
公開日2023-04-26
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (3.93 Å)
主引用文献Molecular architecture of the G alpha i -bound TRPC5 ion channel.
Nat Commun, 14, 2023
7NP4
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cAMP-bound rabbit HCN4 stabilized in LMNG-CHS detergent mixture
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
著者Giese, H, Chaves-Sanjuan, A, Saponaro, A, Clarke, O, Bolognesi, M, Mancia, F, Hendrickson, W.A, Thiel, G, Santoro, B, Moroni, A.
登録日2021-02-26
公開日2021-08-11
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Gating movements and ion permeation in HCN4 pacemaker channels.
Mol.Cell, 81, 2021
7MIJ
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BU of 7mij by Molmil
Mouse TRPV3 in MSP2N2 nanodiscs, closed state at 4 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (1.98 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7MIK
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BU of 7mik by Molmil
Mouse TRPV3 in MSP2N2 nanodiscs, closed state at 42 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7MIL
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BU of 7mil by Molmil
Mouse TRPV3 in MSP2N2 nanodiscs, sensitized state at 42 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7MIN
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BU of 7min by Molmil
Mouse TRPV3 in cNW11 nanodiscs, closed state at 42 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7MIM
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BU of 7mim by Molmil
Mouse TRPV3 in cNW11 nanodiscs, closed state at 4 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7VML
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BU of 7vml by Molmil
Structure of recombinant RyR2 (EGTA dataset, class 1&2, closed state)
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
7VMN
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BU of 7vmn by Molmil
Structure of recombinant RyR2 (EGTA dataset, class 2, closed state)
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
7M6L
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BU of 7m6l by Molmil
High resolution structure of the membrane embedded skeletal muscle ryanodine receptor
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
著者Melville, Z, Kim, K, Clarke, O.B, Marks, A.R.
登録日2021-03-25
公開日2021-08-18
最終更新日2022-01-19
実験手法ELECTRON MICROSCOPY (3.98 Å)
主引用文献High-resolution structure of the membrane-embedded skeletal muscle ryanodine receptor.
Structure, 30, 2022
7VMO
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BU of 7vmo by Molmil
Structure of recombinant RyR2 (Ca2+ dataset, class 1, open state)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
7VMP
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BU of 7vmp by Molmil
Structure of recombinant RyR2 (Ca2+ dataset, class 2, open state)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
7VMQ
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BU of 7vmq by Molmil
Structure of recombinant RyR2 (Ca2+ dataset, class 3, open state)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations
Nat Commun, 13, 2022
7VMM
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BU of 7vmm by Molmil
Structure of recombinant RyR2 (EGTA dataset, class 1, closed state)
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
7VMS
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BU of 7vms by Molmil
Structure of recombinant RyR2 mutant K4593A (Ca2+ dataset)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations
Nat Commun, 13, 2022
7VMR
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BU of 7vmr by Molmil
Structure of recombinant RyR2 mutant K4593A (EGTA dataset)
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
8T0C
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BU of 8t0c by Molmil
TRPV1 in Nanodisc bound with lysophosphatidic acid in all four monomers
分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1
著者Arnold, W.R, Cheng, Y.
登録日2023-05-31
公開日2024-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
8T3L
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BU of 8t3l by Molmil
TRPV1 in nanodisc bound with 2 LPA molecules in neighboring monomers
分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, SODIUM ION, ...
著者Arnold, W.R, Julius, D, Cheng, Y.
登録日2023-06-07
公開日2024-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024

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件を2024-08-07に公開中

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