PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

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5P85	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 338 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.229 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
1WVW	Crystal structures of kinase domain of DAP kinase in complex with small molecular inhibitors 分子名称: Death-associated protein kinase 1 著者 Ueda, Y, Ogata, H, Yamakawa, A, Higuchi, Y. 登録日 2004-12-27 公開日 2006-04-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of kinase domain of DAP kinase To be Published
2APQ	Crystal Structure of an Active Site Mutant of Bovine Pancreatic Ribonuclease A (H119A-RNase A) with a 10-Glutamine expansion in the C-terminal hinge-loop. 分子名称: PHOSPHATE ION, Ribonuclease 著者 Sambashivan, S, Liu, Y, Sawaya, M.R, Gingery, M, Eisenberg, D. 登録日 2005-08-16 公開日 2005-09-13 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure. Nature, 437, 2005
1HIV	CRYSTAL STRUCTURE OF A COMPLEX OF HIV-1 PROTEASE WITH A DIHYDROETHYLENE-CONTAINING INHIBITOR: COMPARISONS WITH MOLECULAR MODELING 分子名称: 4-[(2R)-3-{[(1S,2S,3R,4S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methyl-4-({(1S,2R)-2-methyl-1-[(pyridin-2-ylmethyl)carbamoyl]butyl}carbamoyl)hexyl]amino}-2-{[(naphthalen-1-yloxy)acetyl]amino}-3-oxopropyl]-1H-imidazol-3-ium, HIV-1 PROTEASE 著者 Thanki, N, Wlodawer, A. 登録日 1992-02-12 公開日 1993-10-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of a complex of HIV-1 protease with a dihydroxyethylene-containing inhibitor: comparisons with molecular modeling. Protein Sci., 1, 1992
5P8K	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 353 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.259 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
2ANS	ADIPOCYTE LIPID BINDING PROTEIN COMPLEXED WITH 1-ANILINO-8-NAPHTHALENE SULFONATE 分子名称: 8-ANILINO-1-NAPHTHALENE SULFONATE, ADIPOCYTE LIPID-BINDING PROTEIN, CHLORIDE ION 著者 Ory, J.J, Banaszak, L.J. 登録日 1999-01-19 公開日 1999-07-22 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Studies of the ligand binding reaction of adipocyte lipid binding protein using the fluorescent probe 1, 8-anilinonaphthalene-8-sulfonate. Biophys.J., 77, 1999
2AOD	Crystal structure analysis of HIV-1 protease with a substrate analog P2-NC 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, HIV-1 PROTEASE, ... 著者 Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. 登録日 2005-08-12 公開日 2006-01-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs. Febs J., 272, 2005
1WSF	Co-crystal structure of E.coli RNase HI active site mutant (D134A*) with Mn2+ 分子名称: MANGANESE (II) ION, Ribonuclease HI 著者 Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S. 登録日 2004-11-05 公開日 2005-02-08 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography J.Mol.Biol., 345, 2005
2ASK	Structure of human Artemin 分子名称: SULFATE ION, artemin 著者 Silvian, L, Jin, P, Carmillo, P, Boriack-Sjodin, P.A, Pelletier, C, Rushe, M, Gong, B.J, Sah, D, Pepinsky, B, Rossomando, A. 登録日 2005-08-23 公開日 2006-06-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Artemin crystal structure reveals insights into heparan sulfate binding. Biochemistry, 45, 2006
3FKN	P38 kinase crystal structure in complex with RO7125 分子名称: 3-[2-chloro-5-(methylsulfonyl)phenyl]-6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidine, Mitogen-activated protein kinase 14 著者 Kuglstatter, A, Ghate, M. 登録日 2008-12-17 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Mapping Binding Pocket Volume: Potential Applications towards Ligand Design and Selectivity To be Published
1HLS	NMR STRUCTURE OF THE HUMAN INSULIN-HIS(B16) 分子名称: INSULIN 著者 Ludvigsen, S, Kaarsholm, N.C. 登録日 1995-06-28 公開日 1995-09-15 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 High-resolution structure of an engineered biologically potent insulin monomer, B16 Tyr-->His, as determined by nuclear magnetic resonance spectroscopy. Biochemistry, 33, 1994
2ASU	Crystal Structure of the beta-chain of HGFl/MSP 分子名称: Hepatocyte growth factor-like protein 著者 Carafoli, F, Chirgadze, D.Y, Blundell, T.L, Gherardi, E. 登録日 2005-08-24 公開日 2005-11-10 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of the beta-chain of human hepatocyte growth factor-like/macrophage stimulating protein. Febs J., 272, 2005
3F61	Crystal Structure of M. tuberculosis PknB Leu33Asp/Val222Asp double mutant in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase pknB 著者 Mieczkowski, C.A, Alber, T, TB Structural Genomics Consortium (TBSGC) 登録日 2008-11-05 公開日 2008-12-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Auto-activation mechanism of the Mycobacterium tuberculosis PknB receptor Ser/Thr kinase. Embo J., 27, 2008
3F69	Crystal structure of the Mycobacterium tuberculosis PknB mutant kinase domain in complex with KT5720 分子名称: SULFATE ION, Serine/threonine-protein kinase pknB, hexyl (5S,6R,8R)-6-hydroxy-5-methyl-13-oxo-5,6,7,8-tetrahydro-13H-5,8-epoxy-4b,8a,14-triazadibenzo[b,h]cycloocta[1,2,3,4-jkl]c yclopenta[e]-as-indacene-6-carboxylate 著者 Alber, T, Mieczkowski, C.A, TB Structural Genomics Consortium (TBSGC) 登録日 2008-11-05 公開日 2008-12-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Auto-activation mechanism of the Mycobacterium tuberculosis PknB receptor Ser/Thr kinase. Embo J., 27, 2008
1HO0	NEW B-CHAIN MUTANT OF BOVINE INSULIN 分子名称: INSULIN 著者 Dupradeau, F.Y, Richard, T, Le Flem, G, Oulyadi, H, Prigent, Y, Monti, J.P. 登録日 2000-12-08 公開日 2000-12-20 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A new B-chain mutant of insulin: comparison with the insulin crystal structure and role of sulfonate groups in the B-chain structure J.Pept.Res., 60, 2002
3FMH	P38 kinase crystal structure in complex with 6-(2,4-Difluoro-phenoxy)-8-methyl-2-((R)-1-methyl-2-tetrazol-2-yl-ethylamino)-8H-pyrido[2,3-d]pyrimidin-7-one 分子名称: 6-(2,4-difluorophenoxy)-8-methyl-2-{[(1R)-1-methyl-2-(2H-tetrazol-2-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, Mitogen-activated protein kinase 14 著者 Kuglstatter, A, Ghate, M. 登録日 2008-12-22 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Discovery of Pamapimod and R1487 as Orally Bioavailable and Highly Selective Inhibitors of p38 Map Kinase To be Published
2ATV	The crystal structure of human RERG in the GDP bound state 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAS-like estrogen-regulated growth inhibitor 著者 Turnbull, A.P, Salah, E, Schoch, G, Elkins, J, Burgess, N, Gileadi, O, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC) 登録日 2005-08-26 公開日 2005-10-18 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The crystal structure of human RERG in the GDP bound state To be Published
3TKI	Crystal structure of Chk1 in complex with inhibitor S25 分子名称: N-(2-aminoethyl)-5-(2-{[4-(morpholin-4-yl)pyridin-2-yl]amino}-1,3-thiazol-5-yl)pyridine-3-carboxamide, SULFATE ION, Serine/threonine-protein kinase Chk1 著者 Yan, Y, Ikuta, M. 登録日 2011-08-26 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Pyridyl aminothiazoles as potent inhibitors of Chk1 with slow dissociation rates. Bioorg.Med.Chem.Lett., 22, 2012
2AUO	Residue F4 plays a key role in modulating the oxygen affinity and cooperatrivity in Scapharca dimeric hemoglobin 分子名称: CARBON MONOXIDE, Globin I, PROTOPORPHYRIN IX CONTAINING FE 著者 Knapp, J.E, Bonham, M.A, Gibson, Q.H, Nichols, J.C, Royer Jr, W.E. 登録日 2005-08-28 公開日 2006-03-28 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Residue F4 plays a key role in modulating oxygen affinity and cooperativity in Scapharca dimeric hemoglobin Biochemistry, 44, 2005
2AW2	Crystal structure of the human BTLA-HVEM complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B and T lymphocyte attenuator, NICKEL (II) ION, ... 著者 Compaan, D.M, Gonzalez, L.C, Tom, I, Loyet, K.M, Eaton, D, Hymowitz, S.G. 登録日 2005-08-31 公開日 2005-09-27 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Attenuating Lymphocyte Activity: the crystal structure of the BTLA-HVEM complex J.Biol.Chem., 280, 2005
2AV0	F97L with CO bound 分子名称: CARBON MONOXIDE, Globin I, PROTOPORPHYRIN IX CONTAINING FE 著者 Knapp, J.E, Bonham, M.A, Gibson, Q.H, Nichols, J.C, Royer Jr, W.E. 登録日 2005-08-29 公開日 2006-03-28 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Residue F4 plays a key role in modulating oxygen affinity and cooperativity in Scapharca dimeric hemoglobin Biochemistry, 44, 2005
1WIY	Crystal Structure Analysis of a 6-coordinated Cytochorome P450 from Thermus thermophilus HB8 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Kousumi, Y, Nakagawa, N, Kaneko, M, Yamamoto, H, Masui, R, Kuramitsu, S, Ueyama, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-28 公開日 2004-11-28 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure Analysis of Cytochrome P450 from Thermus thermophilus HB8 To be Published
5P5Y	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 259 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.139 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P6D	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 274 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.439 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P6S	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 289 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.339 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016

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