PDB: 35463 件ウェブページステータス検索Chemie searchBIRD

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7O6O	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-096 分子名称: (5-methanoyl-2-nitro-phenyl) propane-2-sulfonate, 14-3-3 protein sigma, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-04-11 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NV4	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-188 分子名称: 14-3-3 protein sigma, 4-(2,3-dihydroindol-1-ylsulfonyl)benzaldehyde, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-03-15 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NXT	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-183 分子名称: 14-3-3 protein sigma, 4-(2,3-dihydro-1,4-benzoxazin-4-ylsulfonyl)benzaldehyde, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-03-19 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NZK	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-121 分子名称: 14-3-3 protein sigma, 4-[(3~{R})-3-methoxypiperidin-1-yl]sulfonylbenzaldehyde, Transcription factor p65 著者 Wolter, M, Ottmann, C. 登録日 2021-03-24 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O3Q	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-041 分子名称: 14-3-3 protein sigma, 4-methyl-~{N}-(1-methylpyrazol-3-yl)benzenesulfonamide, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-04-02 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7AXZ	Ku70/80 complex apo form 分子名称: X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 6 著者 Hnizda, A, Tesina, P, Novak, P, Blundell, T.L. 登録日 2020-11-10 公開日 2021-02-10 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 SAP domain forms a flexible part of DNA aperture in Ku70/80. Febs J., 288, 2021
7O5A	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-158 分子名称: 14-3-3 protein sigma, 4-(3-methoxyazetidin-1-yl)carbonylbenzaldehyde, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-04-08 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O6G	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-176 分子名称: 14-3-3 protein sigma, 4-[(3~{R})-3-oxidanylpiperidin-1-yl]carbonylbenzaldehyde, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-04-11 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7AH4	Crystal structure of indoleamine 2,3-dioxygenase 1 (IDO1) in complex with ferric heme and MMG-0363 分子名称: 4-chloranyl-2-(2~{H}-1,2,3-triazol-4-yl)aniline, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE 著者 Roehrig, U.F, Reynaud, A, Pojer, F, Michielin, O, Zoete, V. 登録日 2020-09-24 公開日 2021-02-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors. J.Med.Chem., 64, 2021
7AH6	Crystal structure of indoleamine 2,3-dioxygenase 1 (IDO1) in complex with ferric heme and MMG-0752 分子名称: 4-bromanyl-2-(4~{H}-1,2,4-triazol-3-yl)aniline, GLYCEROL, Indoleamine 2,3-dioxygenase 1, ... 著者 Roehrig, U.F, Reynaud, A, Pojer, F, Michielin, O, Zoete, V. 登録日 2020-09-24 公開日 2021-02-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.998 Å) 主引用文献 Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors. J.Med.Chem., 64, 2021
7AQF	Crystal Structure of Small Molecule Inhibitor TM5484 Bound to Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab) 分子名称: 5-Chloro-2-[[2-[3-(furan-3-yl)anilino]-2-oxoacetyl]amino]benzoic acid, Plasminogen activator inhibitor 1 著者 Sillen, M, Strelkov, S.V, Declerck, P.J. 登録日 2020-10-21 公開日 2021-02-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Structural Insight into the Two-Step Mechanism of PAI-1 Inhibition by Small Molecule TM5484. Int J Mol Sci, 22, 2021
5AZG	Crystal structure of LGG-1 complexed with a UNC-51 peptide 分子名称: CADMIUM ION, Protein lgg-1, Serine/threonine-protein kinase unc-51 著者 Watanabe, Y, Fujioka, Y, Noda, N.N. 登録日 2015-10-05 公開日 2015-12-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy. Mol.Cell, 60, 2015
1QP8	CRYSTAL STRUCTURE OF A PUTATIVE FORMATE DEHYDROGENASE FROM PYROBACULUM AEROPHILUM 分子名称: FORMATE DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Peat, T.S, Newman, J, Waldo, G.S, Terwilliger, T.C. 登録日 1999-06-01 公開日 1999-06-11 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The Crystal Structure of a Putative Formate Dehydrogenase from Pyrobaculum Aerophilum To be Published
7AH5	Crystal structure of indoleamine 2,3-dioxygenase 1 (IDO1) in complex with ferric heme and MMG-0706 分子名称: 4-chloranyl-2-(1~{H}-1,2,4-triazol-5-yl)aniline, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE 著者 Roehrig, U.F, Reynaud, A, Pojer, F, Michielin, O, Zoete, V. 登録日 2020-09-24 公開日 2021-02-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors. J.Med.Chem., 64, 2021
7AQG	Crystal Structure of Small Molecule Inhibitor TM5484 Bound to Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) 分子名称: 5-Chloro-2-[[2-[3-(furan-3-yl)anilino]-2-oxoacetyl]amino]benzoic acid, Plasminogen activator inhibitor 1, VHH-2g-42 (Nb42), ... 著者 Sillen, M, Strelkov, S.V, Declerck, P.J. 登録日 2020-10-21 公開日 2021-02-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structural Insight into the Two-Step Mechanism of PAI-1 Inhibition by Small Molecule TM5484. Int J Mol Sci, 22, 2021
1Q6D	Crystal structure of Soybean Beta-Amylase Mutant (M51T) with Increased pH Optimum 分子名称: SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ... 著者 Hirata, A, Adachi, M, Sekine, A, Kang, Y.N, Utsumi, S, Mikami, B. 登録日 2003-08-13 公開日 2004-02-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and Enzymatic Analysis of Soybean {beta}-Amylase Mutants with Increased pH Optimum J.Biol.Chem., 279, 2004
7B24	DtxR-like iron-dependent regulator IdeR (P39G variant) complexed with cobalt and its consensus DNA-binding sequence 分子名称: COBALT (II) ION, DtxR family iron (Metal) dependent repressor, consensus DNA-binding sequence 著者 Maurer, D, Marcos-Torres, F.J, Griese, J.J. 登録日 2020-11-26 公開日 2021-03-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout. Nucleic Acids Res., 49, 2021
7O24	Structure of the foamy viral protease-reverse transcriptase in complex with dsDNA. 分子名称: DNA (5'-D(*AP*AP*CP*AP*GP*AP*GP*TP*GP*CP*GP*AP*CP*AP*CP*CP*TP*GP*AP*TP*TP*CP*CP*A)-3'), DNA (5'-D(*TP*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*CP*TP*G)-3'), Pr125Pol 著者 Nowotny, M, Czarnocki-Cieciura, M. 登録日 2021-03-30 公開日 2021-06-30 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase. J.Virol., 95, 2021
7B1Y	DtxR-like iron-dependent regulator IdeR complexed with cobalt and its consensus DNA-binding sequence 分子名称: COBALT (II) ION, DtxR family iron (Metal) dependent repressor, consensus DNA-binding sequence 著者 Maurer, D, Marcos-Torres, F.J, Griese, J.J. 登録日 2020-11-25 公開日 2021-03-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout. Nucleic Acids Res., 49, 2021
5AWO	Arthrobacter globiformis T6 isomalto-dextranse 分子名称: ACETATE ION, Isomaltodextranase, PHOSPHATE ION 著者 Tonozuka, T. 登録日 2015-07-08 公開日 2015-09-09 最終更新日 2020-02-26 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Crystal Structure and Mutational Analysis of Isomalto-dextranase, a Member of Glycoside Hydrolase Family 27 J.Biol.Chem., 290, 2015
7B23	DtxR-like iron-dependent regulator IdeR complexed with cobalt and the SACE_2689 promoter DNA-binding sequence 分子名称: COBALT (II) ION, DtxR family iron (Metal) dependent repressor, SACE_2689 promoter DNA-binding sequence 著者 Maurer, D, Marcos-Torres, F.J, Griese, J.J. 登録日 2020-11-26 公開日 2021-03-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout. Nucleic Acids Res., 49, 2021
7O0H	Structure of the foamy viral protease-reverse transcriptase dRH in complex with ds DNA. 分子名称: DNA (5'-D(*AP*AP*CP*AP*GP*AP*GP*TP*GP*CP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*CP*TP*G)-3'), Pr125Pol 著者 Nowak, E, Nowacka, M, Nowotny, M. 登録日 2021-03-26 公開日 2021-06-30 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase. J.Virol., 95, 2021
7B20	DtxR-like iron-dependent regulator IdeR complexed with iron and its consensus DNA-binding sequence 分子名称: DtxR family iron (Metal) dependent repressor, FE (II) ION, consensus DNA-binding sequence 著者 Maurer, D, Marcos-Torres, F.J, Griese, J.J. 登録日 2020-11-25 公開日 2021-03-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout. Nucleic Acids Res., 49, 2021
5AZH	Crystal structure of LGG-2 fused with an EEEWEEL peptide 分子名称: EEEWEEL peptide,Protein lgg-2, MAGNESIUM ION 著者 Watanabe, Y, Fujioka, Y, Noda, N.N. 登録日 2015-10-05 公開日 2015-12-30 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy. Mol.Cell, 60, 2015
7O31	Crystal structure of the anti-PAS Fab 1.2 in complex with its epitope peptide and the anti-Kappa VHH domain 分子名称: 1,2-ETHANEDIOL, PAS#1 epitope peptide, anti-Kappa VHH domain, ... 著者 Schilz, J, Schiefner, A, Skerra, A. 登録日 2021-04-01 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope. J.Mol.Biol., 433, 2021

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