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1K33
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Crystal structure analysis of the gp41 core mutant
分子名称: Transmembrane glycoprotein GP41
著者Shu, W, Lu, M.
登録日2001-10-01
公開日2001-10-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion.
Biochemistry, 41, 2002
2KE1
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Molecular Basis of non-modified histone H3 tail Recognition by the First PHD Finger of Autoimmune Regulator
分子名称: Autoimmune regulator, H3K4me0, ZINC ION
著者Chignola, F, Gaetani, M, Rebane, A, Org, T, Mollica, L, Zucchelli, C, Spitaleri, A, Mannella, V, Peterson, P, Musco, G.
登録日2009-01-22
公開日2009-05-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation
Nucleic Acids Res., 37, 2009
1KIT
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BU of 1kit by Molmil
VIBRIO CHOLERAE NEURAMINIDASE
分子名称: CALCIUM ION, SIALIDASE
著者Taylor, G.L, Crennell, S.J, Garman, E.F, Vimr, E.R, Laver, W.G.
登録日1996-06-21
公開日1997-06-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of Vibrio cholerae neuraminidase reveals dual lectin-like domains in addition to the catalytic domain.
Structure, 2, 1994
1RMO
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Probing the Role of Tryptophans in Aequorea Victoria Green Fluorescent Proteins with an Expanded Genetic Code
分子名称: wunen-nonfunctional GFP fusion protein
著者Budisa, N, Pal, P.P, Alefelder, S, Birle, P, Krywcun, T, Rubini, M, Wenger, W, Bae, J.H, Steiner, T.
登録日2003-11-28
公開日2004-06-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Probing the role of tryptophans in Aequorea victoria green fluorescent proteins with an expanded genetic code
Biol.Chem., 385, 2004
1RTL
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BU of 1rtl by Molmil
CRYSTAL STRUCTURE OF HCV NS3 PROTEASE DOMAIN: NS4A PEPTIDE COMPLEX WITH COVALENTLY BOUND PYRROLIDINE-5,5-TRANSLACTAM INHIBITOR
分子名称: N-[(2R,3S)-1-((2S)-2-{[(CYCLOPENTYLAMINO)CARBONYL]AMINO}-3-METHYLBUTANOYL)-2-(1-FORMYL-1-CYCLOBUTYL)PYRROLIDINYL]CYCLOPROPANECARBOXAMIDE, NS3 protease/helicase, NS4A COFACTOR, ...
著者Skarzynski, T, Somers, D.O.N.
登録日2003-12-10
公開日2004-12-14
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Pyrrolidine-5,5-trans-lactams. 4. Incorporation of a P3/P4 urea leads to potent intracellular inhibitors of hepatitis C virus NS3/4A protease
Org.Lett., 5, 2003
1Y6N
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Crystal structure of Epstein-Barr virus IL-10 mutant (A87I) complexed with the soluble IL-10R1 chain
分子名称: Interleukin-10 receptor alpha chain, Viral interleukin-10 homolog
著者Yoon, S.I, Jones, B.C, Logsdon, N.J, Walter, M.R.
登録日2004-12-06
公開日2005-05-03
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain.
Structure, 13, 2005
1YK9
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Crystal structure of a mutant form of the mycobacterial adenylyl cyclase Rv1625c
分子名称: Adenylate cyclase
著者Ketkar, A.D, Shenoy, A.R, Ramagopal, U.A, Visweswariah, S.S, Suguna, K, TB Structural Genomics Consortium (TBSGC)
登録日2005-01-17
公開日2006-01-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A Structural Basis for the Role of Nucleotide Specifying Residues in Regulating the Oligomerization of the Rv1625c Adenylyl Cyclase from M.tuberculosis
J.Mol.Biol., 356, 2006
2IN6
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Wee1 kinase complex with inhibitor PD311839
分子名称: 3-(9-HYDROXY-1,3-DIOXO-4-PHENYL-2,3-DIHYDROPYRROLO[3,4-C]CARBAZOL-6(1H)-YL)PROPANOIC ACID, Wee1-like protein kinase
著者Squire, C.J, Dickson, J.M, Ivanovic, I, Baker, E.N.
登録日2006-10-05
公開日2007-09-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases.
Eur.J.Med.Chem., 43, 2008
1UQV
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SAM domain from Ste50p
分子名称: STE50 PROTEIN
著者Grimshaw, S.J, Mott, H.R, Stott, K.M, Nielsen, P.R, Evetts, K.A, Hopkins, L.J, Nietlispach, D, Owen, D.
登録日2003-10-20
公開日2003-10-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the Sterile {Alpha} Motif (Sam) Domain of the Saccharomyces Cerevisiae Mitogen-Activated Protein Kinase Pathway-Modulating Protein Ste50 and Analysis of its Interaction with the Ste11 Sam
J.Biol.Chem., 279, 2004
1YKB
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Crystal Structure of Insect Cell Expressed IL-22
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Xu, T, Logsdon, N.J, Walter, M.R.
登録日2005-01-17
公開日2005-07-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of insect-cell-derived IL-22.
Acta Crystallogr.,Sect.D, 61, 2005
1YHN
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Structure basis of RILP recruitment by Rab7
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab interacting lysosomal protein, ...
著者Wu, M, Wang, T, Hong, W, Song, H.
登録日2005-01-10
公開日2005-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for recruitment of RILP by small GTPase Rab7.
Embo J., 24, 2005
1RM9
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Probing the Role of Tryptophans in Aequorea Victoria Green Fluorescent Proteins with an Expanded Genetic Code
分子名称: avermectin-sensitive chloride channel GluCl beta/cyan fluorescent protein fusion
著者Budisa, N, Pal, P.P, Alefelder, S, Birle, P, Krywcun, T, Rubini, M, Wenger, W, Bae, J.H, Steiner, T.
登録日2003-11-27
公開日2004-06-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Probing the role of tryptophans in Aequorea victoria green fluorescent proteins with an expanded genetic code
Biol.Chem., 385, 2004
1RMP
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Probing the Role of Tryptophans in Aequorea Victoria Green Fluorescent Proteins with an Expanded Genetic Code
分子名称: SIGF1-GFP fusion protein
著者Budisa, N, Pal, P.P, Alefelder, S, Birle, P, Krywcun, T, Rubini, M, Wenger, W, Bae, J.H, Steiner, T.
登録日2003-11-28
公開日2004-06-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Probing the role of tryptophans in Aequorea victoria green fluorescent proteins with an expanded genetic code
Biol.Chem., 385, 2004
1LHH
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BU of 1lhh by Molmil
ROLE OF PROLINE RESIDUES IN HUMAN LYSOZYME STABILITY: A SCANNING CALORIMETRIC STUDY COMBINED WITH X-RAY STRUCTURE ANALYSIS OF PROLINE MUTANTS
分子名称: HUMAN LYSOZYME
著者Inaka, K, Matsushima, M, Herning, T, Kuroki, R, Yutani, K, Kikuchi, M.
登録日1992-03-27
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Role of proline residues in human lysozyme stability: a scanning calorimetric study combined with X-ray structure analysis of proline mutants.
Biochemistry, 31, 1992
1LMM
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Solution Structure of Psmalmotoxin 1, the First Characterized Specific Blocker of ASIC1a NA+ channel
分子名称: Psalmotoxin 1
著者Escoubas, P, Bernard, C, Lazdunski, M, Darbon, H.
登録日2002-05-02
公開日2003-11-25
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Recombinant production and solution structure of PcTx1, the specific peptide inhibitor of ASIC1a proton-gated cation channels
Protein Sci., 12, 2003
1IC6
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STRUCTURE OF A SERINE PROTEASE PROTEINASE K FROM TRITIRACHIUM ALBUM LIMBER AT 0.98 A RESOLUTION
分子名称: CALCIUM ION, NITRATE ION, PROTEINASE K
著者Betzel, C, Gourinath, S, Kumar, P, Kaur, P, Perbandt, M, Eschenburg, S, Singh, T.P.
登録日2001-03-30
公開日2001-04-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献Structure of a serine protease proteinase K from Tritirachium album limber at 0.98 A resolution.
Biochemistry, 40, 2001
2XN2
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BU of 2xn2 by Molmil
Structure of alpha-galactosidase from Lactobacillus acidophilus NCFM with galactose
分子名称: ALPHA-GALACTOSIDASE, GLYCEROL, IMIDAZOLE, ...
著者Fredslund, F, Abou Hachem, M, Larsen, R.J, Sorensen, P.G, Lo Leggio, L, Svensson, B.
登録日2010-07-30
公開日2011-08-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal Structure of Alpha-Galactosidase from Lactobacillus Acidophilus Ncfm: Insight Into Tetramer Formation and Substrate Binding.
J.Mol.Biol., 412, 2011
2KGI
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Solution structure of JARID1A C-terminal PHD finger in complex with H3(1-9)K4me3
分子名称: H3(1-9)K4me3, Histone demethylase JARID1A, ZINC ION
著者Song, J, Wang, Z, Patel, D.J.
登録日2009-03-12
公開日2009-05-05
最終更新日2020-02-26
実験手法SOLUTION NMR
主引用文献Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
1XYR
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Poliovirus 135S cell entry intermediate
分子名称: Genome polyprotein, Coat protein VP1, Coat protein VP2, ...
著者Bubeck, D, Filman, D.J, Cheng, N, Steven, A.C, Hogle, J.M, Belnap, D.M.
登録日2004-11-10
公開日2005-08-02
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献The structure of the poliovirus 135S cell entry intermediate at 10-angstrom resolution reveals the location of an externalized polypeptide that binds to membranes.
J.Virol., 79, 2005
2KQZ
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Solution structure of the Rpn13 DEUBAD domain
分子名称: Proteasomal ubiquitin receptor ADRM1
著者Chen, X, Lee, B, Finley, D, Walters, K.J.
登録日2009-11-25
公開日2010-05-26
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2.
Mol.Cell, 38, 2010
2I65
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Structural Basis for the Mechanistic Understanding Human CD38 Controlled Multiple Catalysis
分子名称: ADP-ribosyl cyclase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Liu, Q, Kriksunov, I.A, Graeff, R, Munshi, C, Lee, H.C, Hao, Q.
登録日2006-08-28
公開日2006-09-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis.
J.Biol.Chem., 281, 2006
1YY0
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Crystal structure of an RNA duplex containing a 2'-amine substitution and a 2'-amide product produced by in-crystal acylation at a C-A mismatch
分子名称: 5'-R(*GP*CP*AP*GP*AP*(A5M)P*UP*UP*AP*AP*AP*UP*CP*UP*GP*C)-3', 5'-R(*GP*CP*AP*GP*AP*(M5M)P*UP*UP*AP*AP*AP*UP*CP*UP*GP*C)-3', CALCIUM ION
著者Gherghe, C.M, Krahn, J.M, Weeks, K.M.
登録日2005-02-23
公開日2005-10-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structures, reactivity and inferred acylation transition States for 2'-amine substituted RNA.
J.Am.Chem.Soc., 127, 2005
2UXR
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Complex with isocitrate and the protein isocitrate dehydrogenase from the psychrophilic bacterium Desulfotalea psychrophila
分子名称: GLYCEROL, ISOCITRATE DEHYDROGENASE, ISOCITRIC ACID, ...
著者Fedoy, A.-E, Yang, N, Martinez, A, Leiros, H.-K.S, Steen, I.H.
登録日2007-03-29
公開日2008-02-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Functional Properties of Isocitrate Dehydrogenase from the Psychrophilic Bacterium Desulfotalea Psychrophila Reveal a Cold -Active Enzyme with an Unusual High Thermal
J.Mol.Biol., 372, 2007
1Y66
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Dioxane contributes to the altered conformation and oligomerization state of a designed engrailed homeodomain variant
分子名称: 1,4-DIETHYLENE DIOXIDE, ACETIC ACID, CADMIUM ION, ...
著者Hom, G.K, Lassila, J.K, Thomas, L.M, Mayo, S.L.
登録日2004-12-03
公開日2005-03-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Dioxane contributes to the altered conformation and oligomerization state of a designed engrailed homeodomain variant.
Protein Sci., 14, 2005
1LHK
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ROLE OF PROLINE RESIDUES IN HUMAN LYSOZYME STABILITY: A SCANNING CALORIMETRIC STUDY COMBINED WITH X-RAY STRUCTURE ANALYSIS OF PROLINE MUTANTS
分子名称: HUMAN LYSOZYME
著者Inaka, K, Matsushima, M, Herning, T, Kuroki, R, Yutani, K, Kikuchi, M.
登録日1992-03-27
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Role of proline residues in human lysozyme stability: a scanning calorimetric study combined with X-ray structure analysis of proline mutants.
Biochemistry, 31, 1992

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