PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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1O1G	MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE 分子名称: SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL LIGHT CHAIN, ... 著者 Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A. 登録日 2002-11-19 公開日 2002-12-11 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (70 Å) 主引用文献 Molecular modeling of averaged rigor crossbridges from tomograms of insect flight muscle. J.Struct.Biol., 138, 2002
6ZL3	CRYSTAL STRUCTURE OF HRAS IN COMPLEX WITH COMPOUND 18 and GDP 分子名称: (3~{S})-3-[2-[(dimethylamino)methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Kessler, D, Fischer, G, Boettcher, J. 登録日 2020-06-30 公開日 2020-08-19 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.031 Å) 主引用文献 Drugging all RAS isoforms with one pocket. Future Med Chem, 12, 2020
6Z1W	Crystal structure of human steroid carrier protein SL (SCP-2L) mutant A100C 分子名称: OXTOXYNOL-10, Peroxisomal multifunctional enzyme type 2, SULFATE ION 著者 Rozeboom, H.J, Janssen, D.B. 登録日 2020-05-14 公開日 2021-03-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Engineering Thermostability in Artificial Metalloenzymes to Increase Catalytic Activity Acs Catalysis, 11, 2021
6Z1X	Crystal structure of human steroid carrier protein SL (SCP-2L) mutant V83C 分子名称: OXTOXYNOL-10, Peroxisomal multifunctional enzyme type 2, SULFATE ION 著者 Rozeboom, H.J, Janssen, D.B. 登録日 2020-05-14 公開日 2021-03-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Engineering Thermostability in Artificial Metalloenzymes to Increase Catalytic Activity Acs Catalysis, 11, 2021
6YWI	Structure of Chloroflexus aggregans flavin based fluorescent protein (CagFbFP) Q148E variant 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... 著者 Remeeva, A, Nazarenko, V, Kovalev, K, Gushchin, I. 登録日 2020-04-29 公開日 2021-04-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Insights into the mechanisms of light-oxygen-voltage domain color tuning from a set of high-resolution X-ray structures. Proteins, 2021
6YWH	Structure of Chloroflexus aggregans flavin based fluorescent protein (CagFbFP) Q148D variant 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE, Multi-sensor hybrid histidine kinase, ... 著者 Remeeva, A, Nazarenko, V, Kovalev, K, Gushchin, I. 登録日 2020-04-29 公開日 2021-04-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 Insights into the mechanisms of light-oxygen-voltage domain color tuning from a set of high-resolution X-ray structures. Proteins, 2021
6YXC	Structure of Chloroflexus aggregans flavin based fluorescent protein (CagFbFP) Q148R variant 分子名称: FLAVIN MONONUCLEOTIDE, Multi-sensor hybrid histidine kinase, SODIUM ION 著者 Remeeva, A, Nazarenko, V, Kovalev, K, Gushchin, I. 登録日 2020-04-30 公開日 2021-04-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Insights into the mechanisms of light-oxygen-voltage domain color tuning from a set of high-resolution X-ray structures. Proteins, 2021
6YWQ	Structure of Chloroflexus aggregans flavin based fluorescent protein (CagFbFP) Q148H variant 分子名称: FLAVIN MONONUCLEOTIDE, GLYCEROL, Multi-sensor hybrid histidine kinase 著者 Remeeva, A, Nazarenko, V, Kovalev, K, Gushchin, I. 登録日 2020-04-30 公開日 2021-04-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Insights into the mechanisms of light-oxygen-voltage domain color tuning from a set of high-resolution X-ray structures. Proteins, 2021
3I4A	Crystal structure of dimethylarginine dimethylaminohydrolase-1 (DDAH-1) in complex with N5-(1-iminopropyl)-L-ornithine 分子名称: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, N5-(1-iminopropyl)-L-ornithine 著者 Monzingo, A.F, Wang, Y, Hu, S, Schaller, T.H, Fast, W, Robertus, J.D. 登録日 2009-07-01 公開日 2009-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.898 Å) 主引用文献 Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide. Biochemistry, 48, 2009
6YWR	Structure of Chloroflexus aggregans flavin based fluorescent protein (CagFbFP) Q148H variant (space group C2) 分子名称: FLAVIN MONONUCLEOTIDE, Multi-sensor hybrid histidine kinase, SULFATE ION 著者 Remeeva, A, Nazarenko, V, Kovalev, K, Gushchin, I. 登録日 2020-04-30 公開日 2021-04-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Insights into the mechanisms of light-oxygen-voltage domain color tuning from a set of high-resolution X-ray structures. Proteins, 2021
6YWG	Structure of Chloroflexus aggregans flavin based fluorescent protein (CagFbFP) Q148N variant 分子名称: FLAVIN MONONUCLEOTIDE, GLYCEROL, Multi-sensor hybrid histidine kinase 著者 Remeeva, A, Nazarenko, V, Kovalev, K, Gushchin, I. 登録日 2020-04-29 公開日 2021-04-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Insights into the mechanisms of light-oxygen-voltage domain color tuning from a set of high-resolution X-ray structures. Proteins, 2021
6JKK	Crystal structure of BubR1 kinase domain 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Mitotic checkpoint control protein kinase BUB1 著者 Lin, L, Ye, S, Huang, Y, Liu, X, Zhang, R, Yao, X. 登録日 2019-03-01 公開日 2019-06-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res., 29, 2019
6JSF	Crystal Structure of BACE1 in complex with N-(3-((4S,5S)-2-amino-4-methyl-5-phenyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-(fluoromethoxy)pyrazine-2-carboxamide 分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, IODIDE ION, ... 著者 Fujimoto, K, Matsuoka, E, Asada, N, Tadano, G, Yamamoto, T, Nakahara, K, Fuchino, K, Ito, H, Kanegawa, N, Moechars, D, Gijsen, H.J.M, Kusakabe, K.I. 登録日 2019-04-08 公開日 2019-08-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-Based Design of Selective beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: Targeting the Flap to Gain Selectivity over BACE2. J.Med.Chem., 62, 2019
8DHD	Neutron crystal structure of maltotetraose bound tmMBP 分子名称: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose-binding protein MalE2 著者 Cuneo, M.J, Shukla, S, Myles, D.A. 登録日 2022-06-27 公開日 2022-10-12 最終更新日 2023-10-25 実験手法 NEUTRON DIFFRACTION (1.7 Å), X-RAY DIFFRACTION 主引用文献 Mapping periplasmic binding protein oligosaccharide recognition with neutron crystallography. Sci Rep, 12, 2022
6YWA	Human REF STING in complex with 3',3'-c-[2'FdAMP-2'FdAM(PS)] 分子名称: 3',3'-c-[2'FdAMP-2'FdAM(PS)], GLYCEROL, Stimulator of interferon genes protein 著者 Boura, E, Smola, M. 登録日 2020-04-29 公開日 2021-05-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.311 Å) 主引用文献 Human REF STING in complex with 3',3'-c-[2'FdAMP-2'FdAM(PS)] To Be Published
6YWB	Human wtSTING in complex with 3',3'-c-[2'FdAMP-2'FdAM(PS)] 分子名称: 3',3'-c-[2'FdAMP-2'FdAM(PS)], Stimulator of interferon protein 著者 Boura, E, Smola, M. 登録日 2020-04-29 公開日 2021-05-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.503 Å) 主引用文献 Human wtSTING in complex with 3',3'-c-[2'FdAMP-2'FdAM(PS)] To Be Published
2WSM	Crystal structure of Hydrogenase Maturation Factor HypB From Archaeoglobus Fulgidus 分子名称: CHLORIDE ION, HYDROGENASE EXPRESSION/FORMATION PROTEIN (HYPB) 著者 Wong, K.B, Li, T. 登録日 2009-09-08 公開日 2010-09-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Basis for GTP-Dependent Dimerization of Hydrogenase Maturation Factor Hypb. Plos One, 7, 2012
8DEA	Scaffold Hopping via Ring Opening Enables Identification of Acyclic Compounds as New Complement Factor D Inhibitors 分子名称: 1-[(3-acetylphenyl)acetyl]-N-(6-bromopyridin-2-yl)-L-prolinamide, Complement factor D, GLYCEROL 著者 Raman, K, Babu, Y.S. 登録日 2022-06-20 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.214 Å) 主引用文献 Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors. Bioorg.Med.Chem., 74, 2022
8DG6	Scaffold Hopping via Ring Opening Enables Identification of Acyclic Compounds as New Complement Factor D Inhibitors 分子名称: 1-{2-[(2S)-2-{[(3-chloro-2-fluorophenyl)methyl]carbamoyl}pyrrolidin-1-yl]-2-oxoethyl}-1H-indazole-3-carboxamide, Complement factor D 著者 Raman, K, Babu, Y.S. 登録日 2022-06-23 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.986 Å) 主引用文献 Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors. Bioorg.Med.Chem., 74, 2022
5MM8	Atomic resolution structure of SplE protease from Staphylococcus aureus 分子名称: ACETATE ION, Serine protease SplE 著者 Stach, N, Zdzalik, M, Dubin, G. 登録日 2016-12-08 公開日 2018-03-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Unique Substrate Specificity of SplE Serine Protease from Staphylococcus aureus. Structure, 26, 2018
8D95	Scaffold Hopping via Ring Opening Enables Identification of Acyclic Compounds as New Complement Factor D Inhibitors 分子名称: Complement factor D, N-(6-bromopyridin-2-yl)-1-[(3-cyanophenyl)acetyl]-L-prolinamide 著者 Raman, K, Babu, Y.S. 登録日 2022-06-09 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.166 Å) 主引用文献 Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors. Bioorg.Med.Chem., 74, 2022
8DSU	Crystal Structure of SARS CoV-2 Mpro with Pfizer Intravenous Inhibitor PF-00835231 分子名称: 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Shaqra, A.M, Schiffer, C.A. 登録日 2022-07-22 公開日 2023-03-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Crystal Structures of Inhibitor-Bound Main Protease from Delta- and Gamma-Coronaviruses. Viruses, 15, 2023
8E7C	Crystal Structure of Porcine Deltacoronavirus (HKU-15) Mpro with Pfizer Intravenous Inhibitor PF-00835231 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, Main Protease, ... 著者 Shaqra, A.M, Schiffer, C.A. 登録日 2022-08-23 公開日 2023-03-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal Structures of Inhibitor-Bound Main Protease from Delta- and Gamma-Coronaviruses. Viruses, 15, 2023
8E7N	Crystal structure of beluga whale Gammacoronavirus SW1 Mpro with GC-376 captured in two conformational states 分子名称: (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, GLYCEROL, ... 著者 Shaqra, A.M, Schiffer, C.A. 登録日 2022-08-24 公開日 2023-03-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal Structures of Inhibitor-Bound Main Protease from Delta- and Gamma-Coronaviruses. Viruses, 15, 2023
8E84	Human PCNA mutant- C148S 分子名称: Proliferating cell nuclear antigen 著者 Magrino, J, Page, B, Gaubitz, C, Kelch, B.A. 登録日 2022-08-25 公開日 2023-04-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A thermosensitive PCNA allele underlies an ataxia-telangiectasia-like disorder. J.Biol.Chem., 299, 2023

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