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8VHY
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Neutron Structure of Reduced Trp161Phe MnSOD
分子名称: MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial
著者Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Coates, L, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O.
登録日2024-01-02
公開日2024-07-31
最終更新日2024-10-16
実験手法NEUTRON DIFFRACTION (2.3 Å)
主引用文献Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Nat Commun, 15, 2024
2VSE
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Structure and mode of action of a mosquitocidal holotoxin
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, MOSQUITOCIDAL TOXIN
著者Treiber, N, Reinert, D.J, Carpusca, I, Aktories, K, Schulz, G.E.
登録日2008-04-22
公開日2008-07-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Mode of Action of a Mosquitocidal Holotoxin.
J.Mol.Biol., 381, 2008
2VZL
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FERREDOXIN-NADP REDUCTASE (MUTATIONS: T155G, A160T, L263P AND Y303S) COMPLEXED WITH NAD BY COCRYSTALLIZATION
分子名称: FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Herguedas, B, Martinez-Julvez, M, Hermoso, J.A, Peregrina, J.R, Medina, M.
登録日2008-07-28
公開日2009-04-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Protein Motifs Involved in Coenzyme Interaction and Enzymatic Efficiency in Anabaena Ferredoxin-Nadp+ Reductase.
Biochemistry, 48, 2009
2W2T
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Rac2 (G12V) in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2
著者Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H.
登録日2008-11-04
公開日2009-05-05
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
8XRP
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The Cryo-EM structure of IL-12, receptor subunit beta-1 and receptor subunit beta-2 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1, Interleukin-12 receptor subunit beta-2, ...
著者Chen, H.Q, Wang, X.Q, Ge, X.F, Zeng, J.W, Wang, J.W.
登録日2024-01-07
公開日2024-07-24
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Structure and assembly of the human IL-12 signaling complex.
Structure, 32, 2024
2W2V
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Rac2 (G12V) in complex with GTPgS
分子名称: GUANOSINE-5'-TRIPHOSPHATE, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2
著者Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H.
登録日2008-11-04
公開日2009-05-05
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
7TTI
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Human KCC1 bound with VU0463271 In an outward-open state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-cyclopropyl-N-(4-methyl-1,3-thiazol-2-yl)-2-[(6-phenylpyridazin-3-yl)sulfanyl]acetamide, Solute carrier family 12 member 4
著者Zhao, Y.X, Cao, E.H.
登録日2022-02-01
公開日2022-06-29
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of the human cation-chloride cotransport KCC1 in an outward-open state.
Proc.Natl.Acad.Sci.USA, 119, 2022
7U4T
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Human V-ATPase in state 2 with SidK and mEAK-7
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, MTOR-associated protein MEAK7, ...
著者Wang, L, Fu, T.M.
登録日2022-03-01
公開日2022-08-24
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Identification of mEAK-7 as a human V-ATPase regulator via cryo-EM data mining.
Proc.Natl.Acad.Sci.USA, 119, 2022
7TTH
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Human potassium-chloride cotransporter 1 in inward-open state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, POTASSIUM ION, Solute carrier family 12 member 4
著者Zhao, Y.X, Cao, E.H.
登録日2022-02-01
公開日2022-06-29
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structure of the human cation-chloride cotransport KCC1 in an outward-open state.
Proc.Natl.Acad.Sci.USA, 119, 2022
2VCT
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Glutathione transferase A2-2 in complex with delta-4-andostrene-3-17- dione
分子名称: 4-ANDROSTENE-3-17-DIONE, GLUTATHIONE S-TRANSFERASE A2
著者Tars, K, Olin, B, Mannervik, B.
登録日2007-09-27
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for Featuring of Steroid Isomerase Activity in Alpha Class Glutathione Transferases.
J.Mol.Biol., 397, 2010
2V4Z
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The crystal structure of the human G-protein subunit alpha (GNAI3) in complex with an engineered regulator of G-protein signaling type 2 domain (RGS2)
分子名称: GUANINE NUCLEOTIDE-BINDING PROTEIN G(K) SUBUNIT ALPHA, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Roos, A.K, Soundararajan, M, Pike, A.C.W, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Knapp, S.
登録日2008-09-30
公開日2008-11-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Determinants of G-Protein Alpha Subunit Selectivity by Regulator of G-Protein Signaling 2(Rgs2).
J.Biol.Chem., 284, 2009
2VDH
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Crystal structure of Chlamydomonas reinhardtii Rubisco with a large- subunit C172S mutation
分子名称: 1,2-ETHANEDIOL, 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, ...
著者Garcia-Murria, M.-J, Karkehabadi, S, Marin-Navarro, J, Satagopan, S, Andersson, I, Spreitzer, R.J, Moreno, J.
登録日2007-10-09
公開日2008-11-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Functional Consequences of the Replacement of Proximal Residues Cys-172 and Cys-192 in the Large Subunit of Ribulose 1,5-Bisphosphate Carboxylase/Oxygenase from Chlamydomonas Reinhardtii
Biochem.J., 411, 2008
2WHL
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Understanding how diverse mannanases recognise heterogeneous substrates
分子名称: ACETATE ION, BETA-MANNANASE, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose
著者Tailford, L.E, Ducros, V.M.A, Flint, J.E, Roberts, S.M, Morland, C, Zechel, D.L, Smith, N, Bjornvad, M.E, Borchert, T.V, Wilson, K.S, Davies, G.J, Gilbert, H.J.
登録日2009-05-05
公開日2009-05-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Understanding How Diverse -Mannanases Recognise Heterogeneous Substrates.
Biochemistry, 48, 2009
2WJJ
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Structure and function of the FeoB G-domain from Methanococcus jannaschii
分子名称: FERROUS IRON TRANSPORT PROTEIN B HOMOLOG, GUANOSINE-5'-DIPHOSPHATE
著者Koester, S, Wehner, M, Herrmann, C, Kuehlbrandt, W, Yildiz, O.
登録日2009-05-26
公開日2009-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.405 Å)
主引用文献Structure and Function of the Feob G-Domain from Methanococcus Jannaschii
J.Mol.Biol., 392, 2009
2WQO
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STRUCTURE OF NEK2 BOUND TO THE AMINOPYRIDINE CCT241950
分子名称: 4-[2-AMINO-5-(3,4,5-TRIMETHOXYPHENYL)PYRIDIN-3-YL]BENZOIC ACID, CHLORIDE ION, SERINE/THREONINE-PROTEIN KINASE NEK2
著者Mas-Droux, C, Bayliss, R.
登録日2009-08-24
公開日2009-12-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.167 Å)
主引用文献An Autoinhibitory Tyrosine Motif in the Cell-Cycle- Regulated Nek7 Kinase is Released Through Binding of Nek9.
Mol.Cell, 36, 2009
2VCV
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Glutathione transferase A3-3 in complex with glutathione and delta-4- androstene-3-17-dione
分子名称: 4-ANDROSTENE-3-17-DIONE, GLUTATHIONE, GLUTATHIONE S-TRANSFERASE A3
著者Tars, K, Olin, B, Mannervik, B.
登録日2007-09-27
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for Featuring of Steroid Isomerase Activity in Alpha Class Glutathione Transferases.
J.Mol.Biol., 397, 2010
2VM3
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Structure of Alcaligenes xylosoxidans in space group R3 - 1 of 2
分子名称: COPPER (II) ION, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE, TETRAETHYLENE GLYCOL, ...
著者Hough, M.A, Antonyuk, S.V, Strange, R.W, Eady, R.R, Hasnain, S.S.
登録日2008-01-22
公開日2008-02-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystallography with Online Optical and X-Ray Absorption Spectroscopies Demonstrates an Ordered Mechanism in Copper Nitrite Reductase.
J.Mol.Biol., 378, 2008
8XKZ
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Core region of the citrate-induced human acetyl-CoA carboxylase 1 filament (ACC1-citrate)
分子名称: Acetyl-CoA carboxylase 1, BIOTIN
著者Zhou, F.Y, Zhang, Y.Y, Zhou, Q, Hu, Q.
登録日2023-12-25
公開日2024-10-23
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献Filament structures unveil the dynamic organization of human acetyl-CoA carboxylase.
Sci Adv, 10, 2024
9ATC
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ATCASE Y165F MUTANT
分子名称: ASPARTATE TRANSCARBAMOYLASE, ZINC ION
著者Ha, Y, Allewell, N.M.
登録日1998-06-26
公開日1999-07-26
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Intersubunit hydrogen bond acts as a global molecular switch in Escherichia coli aspartate transcarbamoylase.
Proteins, 33, 1998
8Y5J
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Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F.
登録日2024-01-31
公開日2024-07-03
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
2V45
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A New Catalytic Mechanism of Periplasmic Nitrate Reductase from Desulfovibrio desulfuricans ATCC 27774 from Crystallographic and EPR Data and based on detailed analysis of the sixth ligand
分子名称: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, MOLYBDENUM ATOM, ...
著者Najmudin, S, Gonzalez, P.J, Trincao, J, Coelho, C, Mukhopadhyay, A, Romao, C.C, Moura, I, Moura, J.J, Brondino, C.D, Romao, M.J.
登録日2007-06-27
公開日2008-03-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Periplasmic Nitrate Reductase Revisited: A Sulfur Atom Completes the Sixth Coordination of the Catalytic Molybdenum.
J.Biol.Inorg.Chem., 13, 2008
2V74
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Crystal structure of coactivator-associated arginine methyltransferase 1 (CARM1), in complex with S-adenosyl-homocysteine
分子名称: HISTONE-ARGININE METHYLTRANSFERASE CARM1, S-ADENOSYL-L-HOMOCYSTEINE
著者Yue, W.W, Hassler, M, Roe, S.M, Thompson-Vale, V, Pearl, L.H.
登録日2007-07-26
公開日2007-10-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Insights Into Histone Code Syntax from Structural and Biochemical Studies of Carm1 Methyltransferase
Embo J., 26, 2007
2V7E
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Crystal structure of coactivator-associated arginine methyltransferase 1 (CARM1), unliganded
分子名称: HISTONE-ARGININE METHYLTRANSFERASE CARM1, MERCURY (II) ION
著者Yue, W.W, Hassler, M, Roe, S.M, Thompson-Vale, V, Pearl, L.H.
登録日2007-07-30
公開日2007-10-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Insights Into Histone Code Syntax from Structural and Biochemical Studies of Carm1 Methyltransferase
Embo J., 26, 2007
2W1Z
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ROP2 from Toxoplasma gondii: A virulence factor with a protein- kinase fold and no enzymatic activity.
分子名称: ROP2, SULFATE ION
著者Labesse, G, Gelin, M, Bessin, Y, Lebrun, M, Arold, S.T, Dubremetz, J.-F.
登録日2008-10-21
公開日2008-12-09
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Rop2 from Toxoplasma Gondii: A Virulence Factor with a Protein-Kinase Fold and No Enzymatic Activity.
Structure, 17, 2009
2VQA
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Protein-folding location can regulate Mn versus Cu- or Zn-binding. Crystal Structure of MncA.
分子名称: ACETATE ION, MANGANESE (II) ION, SLL1358 PROTEIN
著者Tottey, S, Waldron, K.J, Firbank, S.J, Reale, B, Bessant, C, Sato, K, Gray, J, Banfield, M.J, Dennison, C, Robinson, N.J.
登録日2008-03-12
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Protein-Folding Location Can Regulate Manganese-Binding Versus Copper- or Zinc-Binding.
Nature, 455, 2008

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