PDB: 19228 件ウェブページステータス検索Chemie searchBIRD

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4PPY	Crystal structure of a putative acylhydrolase (BF3764) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution 分子名称: Putative acylhydrolase 著者 Joint Center for Structural Genomics (JCSG) 登録日 2014-02-27 公開日 2014-04-02 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of a putative acylhydrolase (BF3764) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution To be published
4P44	X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a phosphoramidate inhibitor JRB-4-81 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Novakova, Z, Barinka, C. 登録日 2014-03-11 公開日 2015-05-20 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Design of composite inhibitors targeting glutamate carboxypeptidase II: the importance of effector functionalities. Febs J., 283, 2016
4PHX	Crystal structure of AggB, the minor subunit of aggregative adherence fimbriae type I from the Escherichia coli O4H104 分子名称: Protein AggB 著者 Pakharukova, N.A, Tuitilla, M, Zavialov, A.V. 登録日 2014-05-07 公開日 2014-10-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Insight into Host Recognition by Aggregative Adherence Fimbriae of Enteroaggregative Escherichia coli. Plos Pathog., 10, 2014
4POI	Crystal structure of a putative periplasmic protein (BACCAC_02096) from Bacteroides caccae ATCC 43185 at 2.30 A resolution 分子名称: Putative periplasmic protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2014-02-25 公開日 2014-03-12 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of a putative periplasmic protein (BACCAC_02096) from Bacteroides caccae ATCC 43185 at 2.30 A resolution To be published
4O18	Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors 分子名称: 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION 著者 Oh, A, Coons, M, Brillantes, B, Wang, W. 登録日 2013-12-15 公開日 2014-10-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
4O1A	The crystal structure of the mutant NAMPT G217R 分子名称: 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION 著者 Oh, A, Coons, M, Brillantes, B, Wang, W. 登録日 2013-12-15 公開日 2014-10-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
4O2T	Crystal structure of a DUF4827 family protein (BDI_1692) from Parabacteroides distasonis ATCC 8503 at 2.40 A resolution 分子名称: Uncharacterized protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2013-12-17 公開日 2014-02-26 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of a hypothetical protein (BDI_1692) from Parabacteroides distasonis ATCC 8503 at 2.40 A resolution To be published
4O3O	Crystal structure of human polymerase eta inserting datp opposite an 8-oxog containing dna template 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(8OG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, Egli, M. 登録日 2013-12-18 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
4NY0	Crystal structure of FERM domain of human focal adhesion kinase 分子名称: Focal adhesion kinase 1 著者 Walkiewicz, K, Arold, S.T. 登録日 2013-12-10 公開日 2014-03-12 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 FAK dimerization controls its kinase-dependent functions at focal adhesions. Embo J., 33, 2014
4O07	Identification of novel HSP90/isoform selective inhibitors using structure-based drug design. Demonstration of potential utility in treating CNS disorders such as Huntington's disease 分子名称: 2,7,7-trimethyl-9-[8-(2-methylpropyl)-1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl]-1,2,3,4,6,7,8,9-octahydro-5H-beta-carbolin-5-one, Heat shock protein HSP 90-alpha 著者 Zuccola, H.J, Ernst, J.T. 登録日 2013-12-13 公開日 2014-04-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Identification of Novel HSP90 alpha / beta Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration of Potential Utility in Treating CNS Disorders such as Huntington's Disease. J.Med.Chem., 57, 2014
4O1B	The crystal structure of a mutant NAMPT (G217R) in complex with an inhibitor APO866 分子名称: (2E)-N-{4-[1-(benzenecarbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide, 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, ... 著者 Oh, A, Coons, M, Brillantes, B, Wang, W. 登録日 2013-12-15 公開日 2014-10-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
4O12	Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase 分子名称: 2-[6-(4-chlorophenoxy)hexyl]-1-cyano-3-pyridin-4-ylguanidine, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION 著者 Oh, A, Wang, W. 登録日 2013-12-14 公開日 2014-06-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.498 Å) 主引用文献 Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase. Chembiochem, 15, 2014
4O3S	Crystal structure of human polymerase eta extending an 8-oxog dna lesion: post insertion of 8-oxog-dc pair 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*C)-3'), DNA (5'-D(*CP*AP*TP*GP*(8OG)P*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, Egli, M. 登録日 2013-12-18 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.717 Å) 主引用文献 Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
4O46	14-3-3-gamma in complex with influenza NS1 C-terminal tail phosphorylated at S228 分子名称: 14-3-3 protein gamma, Nonstructural protein 1, UNKNOWN ATOM OR ION, ... 著者 Qin, S, Liu, Y, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2013-12-18 公開日 2014-04-30 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1. Nat Commun, 5, 2014
4O1D	Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors 分子名称: (2E)-N-{4-[1-(benzenecarbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide, 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, ... 著者 Oh, A, Coons, M, Brillantes, B, Wang, W. 登録日 2013-12-15 公開日 2014-10-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.705 Å) 主引用文献 Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
4O61	Structure of human ALKBH5 crystallized in the presence of citrate 分子名称: CITRIC ACID, GLYCEROL, RNA demethylase ALKBH5, ... 著者 Tempel, W, Chao, X, Liu, K, Dong, A, Cerovina, T, He, H, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2013-12-20 公開日 2014-02-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation. J.Biol.Chem., 289, 2014
2X0B	Crystal structure of human angiotensinogen complexed with renin 分子名称: ANGIOTENSINOGEN, RENIN 著者 Zhou, A, Wei, Z, Yan, Y, Carrell, R.W, Read, R.J. 登録日 2009-12-08 公開日 2010-10-20 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (4.33 Å) 主引用文献 A Redox Switch in Angiotensinogen Modulates Angiotensin Release. Nature, 468, 2010
4NRD	Crystal structure of a putative GDSL-like lipase (BACOVA_04955) from Bacteroides ovatus ATCC 8483 at 2.10 A resolution 分子名称: 1,2-ETHANEDIOL, Uncharacterized protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2013-11-26 公開日 2013-12-25 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of a hypothetical protein (BACOVA_04955) from Bacteroides ovatus ATCC 8483 at 2.10 A resolution To be published
4NW2	Tandem chromodomains of human CHD1 in complex with Influenza virus NS1 C-terminal tail trimethylated at K229 分子名称: Chromodomain-helicase-DNA-binding protein 1, GLYCEROL, Nonstructural protein 1, ... 著者 Qin, S, Tempel, W, Xu, C, El Bakkouri, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2013-12-05 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1. Nat Commun, 5, 2014
2XBG	Crystal Structure of YCF48 from Thermosynechococcus elongatus 分子名称: YCF48-LIKE PROTEIN 著者 Michoux, F, Takasaka, K, Nixon, P, Murray, J.W. 登録日 2010-04-09 公開日 2011-04-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Ycf48 involved in the biogenesis of the oxygen-evolving photosystem II complex is a seven-bladed beta-propeller protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4O14	Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors 分子名称: 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION 著者 Oh, A, Coons, M, Brillantes, B, Wang, W. 登録日 2013-12-15 公開日 2014-10-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.871 Å) 主引用文献 Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
4O1C	The crystal structures of a mutant NAMPT H191R 分子名称: 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION 著者 Oh, A, Coons, M, Brillantes, B, Wang, W. 登録日 2013-12-15 公開日 2014-10-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.092 Å) 主引用文献 Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
4O3P	Crystal structure of human polymerase eta inserting dctp opposite an 8-oxog containing dna template 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(8OG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, Egli, M. 登録日 2013-12-18 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
2XEG	Human glutamate carboxypeptidase II in complex with Antibody- Recruiting Molecule ARM-P4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Zhang, A.X, Murelli, R.P, Barinka, C, Michel, J, Cocleaza, A, Jorgensen, W.L, Lubkowski, J, Spiegel, D.A. 登録日 2010-05-14 公開日 2010-09-08 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed by Antibody-Recruiting Small Molecules. J.Am.Chem.Soc., 132, 2010
2XEJ	Human glutamate carboxypeptidase II in complex with ARM-M4, urea- based inhibitor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Zhang, A.X, Murelli, R, Barinka, C, Michel, J, Cocleaza, A, Jorgensen, W.L, Lubkowski, J, Spiegel, D.A. 登録日 2010-05-14 公開日 2010-09-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed by Antibody-Recruiting Small Molecules. J.Am.Chem.Soc., 132, 2010

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