4O1A
The crystal structure of the mutant NAMPT G217R
Summary for 4O1A
Entry DOI | 10.2210/pdb4o1a/pdb |
Related | 4O13 4O14 4O15 4O16 4O17 4O18 4O19 4O1B 4O1C 4O1D 4O28 |
Descriptor | Nicotinamide phosphoribosyltransferase, PHOSPHATE ION, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P43490 |
Total number of polymer chains | 2 |
Total formula weight | 114961.47 |
Authors | Oh, A.,Coons, M.,Brillantes, B.,Wang, W. (deposition date: 2013-12-15, release date: 2014-10-22, Last modification date: 2024-02-28) |
Primary citation | Wang, W.,Elkins, K.,Oh, A.,Ho, Y.C.,Wu, J.,Li, H.,Xiao, Y.,Kwong, M.,Coons, M.,Brillantes, B.,Cheng, E.,Crocker, L.,Dragovich, P.S.,Sampath, D.,Zheng, X.,Bair, K.W.,O'Brien, T.,Belmont, L.D. Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9:e109366-e109366, 2014 Cited by PubMed: 25285661DOI: 10.1371/journal.pone.0109366 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
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