PDB: 46200 件ウェブページステータス検索Chemie searchBIRD

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7SZQ	Human P300 complexed with an azaindazole inhibitor 分子名称: 1-[1-(4-chlorophenyl)cyclopentane-1-carbonyl]-N-1H-pyrazolo[4,3-b]pyridin-5-yl-D-prolinamide, Histone acetyltransferase p300 著者 Shewchuk, L.M, Reid, R.A. 登録日 2021-11-29 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening. J.Med.Chem., 65, 2022
7SSK	Human P300 complexed with a glycine-based inhibitor 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Histone acetyltransferase p300, ... 著者 Shewchuk, L.M, Reid, R.A. 登録日 2021-11-11 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening. J.Med.Chem., 65, 2022
7SS8	Human P300 complexed with a proline-based inhibitor 分子名称: 1,2-ETHANEDIOL, 1-[1-(4-chlorophenyl)cyclopentane-1-carbonyl]-N-{[3-(methylcarbamoyl)phenyl]methyl}-D-prolinamide, Histone acetyltransferase p300, ... 著者 Shewchuk, L.M, Reid, R.A. 登録日 2021-11-10 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening. J.Med.Chem., 65, 2022
5KO9	Crystal Structure of the SRAP Domain of Human HMCES Protein 分子名称: Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein, UNKNOWN ATOM OR ION 著者 Halabelian, L, Li, Y, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) 登録日 2016-06-29 公開日 2016-08-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition. Nat.Struct.Mol.Biol., 26, 2019
2VI6	Crystal Structure of the Nanog Homeodomain 分子名称: HOMEOBOX PROTEIN NANOG 著者 Jauch, R, Ng, C.K.L, Saitakendu, K.S, Stevens, R.C, Kolatkar, P.R. 登録日 2007-11-28 公開日 2008-01-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure and DNA Binding of the Homeodomain of the Stem Cell Transcription Factor Nanog. J.Mol.Biol., 376, 2008
5A78	Crystal structure of the homing endonuclease I-CvuI in complex with I- CreI target (C1221) in the presence of 2 mM Mg revealing DNA not cleaved 分子名称: 24MER DNA, 5'-D(*TP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP *CP*GP*AP*CP*GP*TP*TP*TP*TP*GP*A)-3', DNA ENDONUCLEASE I-CVUI, ... 著者 Molina, R, Redondo, P, LopezMendez, B, Villate, M, Merino, N, Blanco, F.J, Valton, J, Grizot, S, Duchateau, P, Prieto, J, Montoya, G. 登録日 2015-07-03 公開日 2015-09-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of the Homing Endonuclease I-Cvui Provides a New Template for Genome Modification J.Biol.Chem., 290, 2015
1QUQ	COMPLEX OF REPLICATION PROTEIN A SUBUNITS RPA14 AND RPA32 分子名称: PROTEIN (REPLICATION PROTEIN A 14 KD SUBUNIT), PROTEIN (REPLICATION PROTEIN A 32 KD SUBUNIT) 著者 Bochkarev, A, Bochkareva, E, Frappier, L, Edwards, A.M. 登録日 1999-07-02 公開日 1999-08-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single-stranded DNA binding. EMBO J., 18, 1999
6M5U	The coordinates of the monomeric terminase complex in the presence of the ADP-BeF3 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... 著者 Yang, Y.X, Yang, P, Wang, N, Zhu, L, Zhou, Z.H, Rao, Z.H, Wang, X.X. 登録日 2020-03-11 公開日 2020-10-28 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation. Protein Cell, 11, 2020
6M5S	The coordinates of the apo hexameric terminase complex 分子名称: Tripartite terminase subunit 1, Tripartite terminase subunit 2, Tripartite terminase subunit 3, ... 著者 Yang, Y.X, Yang, P, Wang, N, Chen, Z.H, Zhou, Z.H, Rao, Z.H, Wang, X.X. 登録日 2020-03-11 公開日 2020-10-28 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation. Protein Cell, 11, 2020
4EKF	Structure of the Inactive Adenovirus Proteinase at 0.98 Angstrom Resolution 分子名称: Adenain, SODIUM ION 著者 Baniecki, M.L, McGrath, W.J, Mangel, W.F. 登録日 2012-04-09 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 Regulation of a Viral Proteinase by a Peptide and DNA in One-dimensional Space: III. ATOMIC RESOLUTION STRUCTURE OF THE NASCENT FORM OF THE ADENOVIRUS PROTEINASE. J.Biol.Chem., 288, 2013
5ITM	The structure of truncated histone-like protein 分子名称: AbrB family transcriptional regulator 著者 Lin, B.L, Chen, C.Y, Huang, C.H, Ko, T.P, Chiang, C.H, Lin, K.F, Chang, Y.C, Lin, P.Y, Tsai, H.H.G, Wang, A.H.J. 登録日 2016-03-17 公開日 2017-01-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The Arginine Pairs and C-Termini of the Sso7c4 from Sulfolobus solfataricus Participate in Binding and Bending DNA. PLoS ONE, 12, 2017
3P7N	Crystal structure of light activated transcription factor El222 from Erythrobacter litoralis 分子名称: FLAVIN MONONUCLEOTIDE, Sensor histidine kinase 著者 McNulty, R, Luecke, H. 登録日 2010-10-12 公開日 2011-05-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis of photosensitivity in a bacterial light-oxygen-voltage/helix-turn-helix (LOV-HTH) DNA-binding protein. Proc.Natl.Acad.Sci.USA, 108, 2011
6M5V	The coordinate of the hexameric terminase complex in the presence of the ADP-BeF3 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... 著者 Yang, Y.X, Yang, P, Wang, N, Chen, Z.H, Zhou, Z.H, Rao, Z.H, Wang, X.X. 登録日 2020-03-11 公開日 2020-10-28 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation. Protein Cell, 11, 2020
6YJ2	Structural and DNA binding studies of the transcriptional repressor Rv2506 (BkaR) from Mycobacterium tuberculosis supports a role in L-Leucine catabolism 分子名称: GLYCEROL, Probable transcriptional regulatory protein (Probably TetR-family) 著者 Keep, N.H, Pritchard, J.E, Sula, A, Cole, A.R, Kendall, S.L. 登録日 2020-04-02 公開日 2021-04-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and DNA binding studies of the transcriptional repressor Rv2506 (BkaR) from Mycobacterium tuberculosis supports a role in L-Leucine catabolism To be published
7SS5	Activated SgrAI endonuclease DNA-bound dimer with Ca2+ and intact primary site DNA 分子名称: CALCIUM ION, DNA (5'-D(P*GP*GP*TP*CP*TP*TP*CP*AP*CP*AP*CP*CP*GP*GP*TP*GP*TP*GP*AP*AP*GP*AP*CP*C)-3'), SgraIR restriction enzyme 著者 Shan, Z, Lyumkis, D, Horton, N.C. 登録日 2021-11-09 公開日 2021-12-01 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Pretransition state and apo structures of the filament-forming enzyme SgrAI elucidate mechanisms of activation and substrate specificity. J.Biol.Chem., 298, 2022
6ZA3	Structure of the transcriptional repressor Atu1419 (VanR) from agrobacterium fabrum in complex a palindromic DNA (C2221 space group) 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... 著者 Morera, S, Vigouroux, A, Legrand, P. 登録日 2020-06-04 公開日 2020-12-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum. Nucleic Acids Res., 49, 2021
6JGW	Crystal structure of the transcriptional regulator CadR from P. putida in complex with DNA 分子名称: CadR, DNA (27-MER) 著者 Liu, X.C, Gan, J.H, Chen, H. 登録日 2019-02-15 公開日 2019-09-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Selective cadmium regulation mediated by a cooperative binding mechanism in CadR. Proc.Natl.Acad.Sci.USA, 116, 2019
6JNI	Crystal structure of the transcriptional regulator CadR from P. putida in complex with Zinc(II) and DNA 分子名称: CadR, DNA (25-MER), ZINC ION 著者 Liu, X.C, Gan, J.H, Chen, H. 登録日 2019-03-16 公開日 2019-09-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Selective cadmium regulation mediated by a cooperative binding mechanism in CadR. Proc.Natl.Acad.Sci.USA, 116, 2019
7N99	SDE2 SAP domain apo structure 分子名称: Isoform 2 of Replication stress response regulator SDE2 著者 Paung, Y, Weinheimer, A.S, Rageul, J, Khan, A, Ho, B, Tong, M, Alphonse, S, Seeliger, M.A, Kim, H. 登録日 2021-06-17 公開日 2022-10-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Extended DNA-binding interfaces beyond the canonical SAP domain contribute to the function of replication stress regulator SDE2 at DNA replication forks. J.Biol.Chem., 298, 2022
6NE0	Structure of double-stranded target DNA engaged Csy complex from Pseudomonas aeruginosa (PA-14) 分子名称: CRISPR RNA (60-MER), CRISPR target DNA (44-MER), CRISPR-associated endonuclease Cas6/Csy4, ... 著者 Chowdhury, S, Rollins, M.F, Carter, J, Golden, S.M, Miettinen, H.M, Santiago-Frangos, A, Faith, D, Lawrence, M.C, Wiedenheft, B, Lander, G.C. 登録日 2018-12-15 公開日 2018-12-26 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure Reveals a Mechanism of CRISPR-RNA-Guided Nuclease Recruitment and Anti-CRISPR Viral Mimicry. Mol. Cell, 74, 2019
5ITJ	The structure of histone-like protein 分子名称: AbrB family transcriptional regulator, SULFATE ION, TETRAETHYLENE GLYCOL 著者 Lin, B.L, Chen, C.Y, Huang, C.H, Ko, T.P, Chiang, C.H, Lin, K.F, Chang, Y.C, Lin, P.Y, Tsai, H.H.G, Wang, A.H.J. 登録日 2016-03-17 公開日 2017-01-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 The Arginine Pairs and C-Termini of the Sso7c4 from Sulfolobus solfataricus Participate in Binding and Bending DNA. PLoS ONE, 12, 2017
6WG6	Crystal structure of human SMC1-SMC3 hinge domain heterodimer in north-open conformation 分子名称: Structural maintenance of chromosomes protein, Structural maintenance of chromosomes protein 3, poly(dT) 著者 Shi, Z.B, Yu, H. 登録日 2020-04-04 公開日 2020-05-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.54 Å) 主引用文献 Cryo-EM structure of the human cohesin-NIPBL-DNA complex. Science, 368, 2020
6ZAB	Structure of the transcriptional repressor Atu1419 (VanR) from agrobacterium fabrum in complex a palindromic DNA (P6422 space group) 分子名称: 1,2-ETHANEDIOL, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Morera, S, Naretto, A, Vigouroux, A, Legrand, P. 登録日 2020-06-05 公開日 2020-12-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum. Nucleic Acids Res., 49, 2021
6M5R	The coordinates of the apo monomeric terminase complex 分子名称: Tripartite terminase subunit 1, Tripartite terminase subunit 2, Tripartite terminase subunit 3, ... 著者 Yang, Y.X, Yang, P, Wang, N, Chen, Z.H, Zhou, Z.H, Rao, Z.H, Wang, X.X. 登録日 2020-03-11 公開日 2020-10-28 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation. Protein Cell, 11, 2020
4L85	Crystal structure of receiver domain of KdpE D52A mutant from E. coli 分子名称: IODIDE ION, KDP operon transcriptional regulatory protein KdpE 著者 Kumar, S, Yernool, D.A. 登録日 2013-06-15 公開日 2014-02-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.202 Å) 主引用文献 An asymmetric heterodomain interface stabilizes a response regulator-DNA complex. Nat Commun, 5, 2014

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