PDB: 13258 件ウェブページステータス検索Chemie searchBIRD

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4XRS	Heterodimeric complex of transcription factors MEIS1 and DLX3 on specific DNA 分子名称: DNA (5'-D(P*AP*CP*AP*AP*TP*TP*AP*TP*CP*CP*TP*GP*TP*CP*AP*AP*C)-3'), DNA (5'-D(P*CP*AP*AP*TP*TP*AP*TP*CP*CP*TP*GP*TP*CP*AP*A)-3'), DNA (5'-D(P*GP*TP*TP*GP*AP*CP*AP*GP*GP*AP*TP*AP*AP*TP*TP*GP*TP*T)-3'), ... 著者 Jorma, A, Yin, Y, Nitta, K.R, Dave, K, Enge, M, Kivioja, T, Popov, A, Morgunova, E, Taipale, J. 登録日 2015-01-21 公開日 2015-11-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature, 527, 2015
4Y32	Crystal structure of C-terminal modified Tau peptide-hybrid 109B with 14-3-3sigma 分子名称: (2S)-2-(2-methoxyethyl)pyrrolidine, 14-3-3 protein sigma, ARG-THR-PRO-SEP-LEU-PRO-CNC(C(C)O)C(=O)N1CCCC1CCOC 著者 Bartel, M, Milroy, L, Bier, D, Brunsveld, L, Ottmann, C. 登録日 2015-02-10 公開日 2015-12-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Stabilizer-Guided Inhibition of Protein-Protein Interactions. Angew.Chem.Int.Ed.Engl., 54, 2015
7TAD	CryoEM structure of the (NPR1)2-(TGA3)2 complex 分子名称: PALMITIC ACID, Regulatory protein NPR1, Transcription factor TGA3, ... 著者 Wu, Q, Zhou, Y, Bartesaghi, A, Dong, X, Zhou, P. 登録日 2021-12-20 公開日 2022-03-16 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis of NPR1 in activating plant immunity. Nature, 605, 2022
4QHU	Crystal Structure of IL-17A/Fab6785 complex 分子名称: CHLORIDE ION, Fab6785 heavy chain, Fab6785 light chain, ... 著者 Luo, J, Gilliland, G.L, Malia, T, Obmolova, G, Teplyakov, A. 登録日 2014-05-29 公開日 2015-08-05 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 IL-17A Asymmetry in a Complex with a Neutralizing Antibody Fab6785 Reveals a Potential Mechanism of Receptor Differentiation To be Published
7TAC	Cryo-EM structure of the (TGA3)2-(NPR1)2-(TGA3)2 complex 分子名称: PALMITIC ACID, Regulatory protein NPR1, Transcription factor TGA3, ... 著者 Wu, Q, Zhou, Y, Bartesaghi, A, Dong, X, Zhou, P. 登録日 2021-12-20 公開日 2022-03-16 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis of NPR1 in activating plant immunity. Nature, 605, 2022
7Z2M	Crystal Structure of the 11.003 Fab in complex with human IL-17A 分子名称: 11.003 Fab heavy-chain, 11.003 Fab light-chain, GLYCEROL, ... 著者 Rondeau, J.M, Lehmann, S. 登録日 2022-02-28 公開日 2023-02-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.899 Å) 主引用文献 "Redirecting an anti-IL-1 beta antibody to bind a new, unrelated and computationally predicted epitope on hIL-17A". Commun Biol, 6, 2023
4XZR	Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh1 分子名称: Importin subunit alpha, Inner nuclear membrane protein SRC1 著者 Lokareddy, R.K, Cingolani, G. 登録日 2015-02-04 公開日 2015-06-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2. Structure, 23, 2015
1PUF	Crystal Structure of HoxA9 and Pbx1 homeodomains bound to DNA 分子名称: 5'-D(*AP*CP*TP*CP*TP*AP*TP*GP*AP*TP*TP*TP*AP*CP*GP*AP*CP*GP*CP*T)-3', 5'-D(*TP*AP*GP*CP*GP*TP*CP*GP*TP*AP*AP*AP*TP*CP*AP*TP*AP*GP*AP*G)-3', Homeobox protein Hox-A9, ... 著者 Laronde-Leblanc, N.A, Wolberger, C. 登録日 2003-06-24 公開日 2003-09-02 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 STRUCTURE OF HOXA9 AND PBX1 BOUND TO DNA: HOX HEXAPEPTIDE AND DNA RECOGNITION ANTERIOR TO POSTERIOR Genes Dev., 17, 2003
8EU9	Class1 of the INO80-Nucleosome complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... 著者 Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. 登録日 2022-10-18 公開日 2023-07-12 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.48 Å) 主引用文献 Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
8ETU	Class2 of the INO80-Hexasome complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... 著者 Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. 登録日 2022-10-17 公開日 2023-07-19 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
8ETS	Class1 of the INO80-Hexasome complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... 著者 Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. 登録日 2022-10-17 公開日 2023-07-19 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
5MKE	cryoEM Structure of Polycystin-2 in complex with cations and lipids 分子名称: 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Wilkes, M, Madej, M.G, Ziegler, C. 登録日 2016-12-04 公開日 2017-01-18 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Molecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2. Nat. Struct. Mol. Biol., 24, 2017
8ETW	Class3 of INO80-Hexasome complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... 著者 Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F. 登録日 2022-10-17 公開日 2023-07-19 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.64 Å) 主引用文献 Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
6P5O	The structure of rat cytosolic PEPCK in complex with 3-(carboxymethylthiol)-picolinic acid 分子名称: 3-[(carboxymethyl)sulfanyl]pyridine-2-carboxylic acid, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... 著者 Mcleod, M.J, Holyoak, T. 登録日 2019-05-30 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Characterization of 3-[(Carboxymethyl)thio]picolinic Acid: A Novel Inhibitor of Phosphoenolpyruvate Carboxykinase. Biochemistry, 58, 2019
6P8H	Crystal structure of CDK4 in complex with CyclinD1 and P21 分子名称: Cyclin-dependent kinase 4, Cyclin-dependent kinase inhibitor 1, G1/S-specific cyclin-D1 著者 Guiley, K.Z, Stevenson, J.W, Lou, K, Barkovich, K.J, Bunch, K, Tripathi, S.M, Shokat, K.M, Rubin, S.M. 登録日 2019-06-07 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition. Science, 366, 2019
4XZV	Crystal Structure of SLMO1-TRIAP1 Complex 分子名称: Maltose-binding periplasmic protein,TP53-regulated inhibitor of apoptosis 1, Protein slowmo homolog 1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Miliara, X, Garnett, J.A, Matthews, S.J. 登録日 2015-02-05 公開日 2016-01-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.58 Å) 主引用文献 Structural insight into the TRIAP1/PRELI-like domain family of mitochondrial phospholipid transfer complexes. Embo Rep., 16, 2015
5JU7	DNA BINDING DOMAIN OF E.COLI CADC 分子名称: Transcriptional activator CadC, ZINC ION 著者 Janowski, R, Schlundt, A, Sattler, M, Niessing, D. 登録日 2016-05-10 公開日 2017-04-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator. Sci Rep, 7, 2017
5MKF	cryoEM Structure of Polycystin-2 in complex with calcium and lipids 分子名称: 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Wilkes, M, Madej, M.G, Ziegler, C. 登録日 2016-12-04 公開日 2017-01-18 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Molecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2. Nat. Struct. Mol. Biol., 24, 2017
5MPI	Structural Basis of Gene Regulation by the Grainyhead Transcription Factor Superfamily 分子名称: Grainyhead-like protein 1 homolog 著者 Ming, Q, Roske, Y, Schuetz, A, Walentin, K, Ibraimi, I, Schmidt-Ott, K.M, Heinemann, U. 登録日 2016-12-16 公開日 2018-01-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.345 Å) 主引用文献 Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family. Nucleic Acids Res., 46, 2018
5QSK	PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434906 分子名称: (benzyloxy)acetic acid, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-08-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 PanDDA analysis group deposition To Be Published
7YNQ	PiB-bound alpha-synuclein fibrils conformation 2 分子名称: 2-[4-(methylamino)phenyl]-1,3-benzothiazol-6-ol, Alpha-synuclein 著者 Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. 登録日 2022-07-31 公開日 2023-08-02 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 PiB-bound alpha-synuclein fibrils conformation 2 To Be Published
7YNT	pFTAA-bound alpha-synuclein fibrils 分子名称: Alpha-synuclein 著者 Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. 登録日 2022-07-31 公開日 2023-08-02 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 pFTAA-bound alpha-synuclein fibrils To Be Published
7YNM	ThT-bound alpha-synuclein fibrils conformation 1 分子名称: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, Alpha-synuclein 著者 Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. 登録日 2022-07-31 公開日 2023-08-02 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 ThT-bound alpha-synuclein fibrils conformation 1 To Be Published
7YNL	EB-bound alpha-synuclein fibrils 分子名称: 4-azanyl-6-[[4-[4-[(~{E})-(8-azanyl-1-oxidanyl-5,7-disulfo-naphthalen-2-yl)diazenyl]-3-methyl-phenyl]-2-methyl-phenyl]diazenyl]-5-oxidanyl-naphthalene-1,3-disulfonic acid, Alpha-synuclein 著者 Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. 登録日 2022-07-31 公開日 2023-08-02 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 EB-bound alpha-synuclein fibrils To Be Published
7YNR	C05-03-bound alpha-synuclein fibrils 分子名称: Alpha-synuclein 著者 Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. 登録日 2022-07-31 公開日 2023-08-02 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 C05-03-bound alpha-synuclein fibrils To Be Published

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