PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

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7QLG	CRYSTAL STRUCTURE OF E.coli ALCOHOL DEHYDROGENASE - FucO MUTANT L259V COMPLEXED WITH FE, NADH, AND GLYCEROL 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FE (III) ION, GLYCEROL, ... 著者 Sridhar, S, Kiema, T.R, Widertsen, M, Wierenga, R.K. 登録日 2021-12-20 公開日 2022-12-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures and kinetic studies of a laboratory evolved aldehyde reductase explain the dramatic shift of its new substrate specificity. Iucrj, 10, 2023
6Q92	Crystal structure of human Arginase-1 at pH 7.0 in complex with ABH 分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, MANGANESE (II) ION, ... 著者 Grobben, Y, Uitdehaag, J.C.M, Zaman, G.J.R. 登録日 2018-12-17 公開日 2019-12-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158. J Struct Biol X, 4, 2020
7QNN	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with inhibitor (surface entropy reduction mutant) 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Steroid C26-monooxygenase, ethyl 1-(cyclopentylmethyl)-5-pyridin-4-yl-indole-2-carboxylate 著者 Snee, M, Tunnicliffe, R, Leys, D, Levy, C, Katariya, M. 登録日 2021-12-21 公開日 2022-12-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
3UIV	Human serum albumin-myristate-amantadine hydrochloride complex 分子名称: (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, MYRISTIC ACID, Serum albumin 著者 Yang, F, Ma, Z, Ma, L, Yang, G. 登録日 2011-11-06 公開日 2012-11-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis of the drug-binding specificity of human serum albumin TO BE PUBLISHED
4NUL	CLOSTRIDIUM BEIJERINCKII FLAVODOXIN MUTANT: D58P OXIDIZED 分子名称: FLAVIN MONONUCLEOTIDE, FLAVODOXIN 著者 Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R. 登録日 1996-12-13 公開日 1997-03-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes. Biochemistry, 36, 1997
4NLL	CLOSTRIDIUM BEIJERINCKII FLAVODOXIN MUTANT: G57D OXIDIZED 分子名称: FLAVIN MONONUCLEOTIDE, FLAVODOXIN 著者 Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R. 登録日 1996-12-16 公開日 1997-03-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes. Biochemistry, 36, 1997
3UJS	Asymmetric complex of human neuron specific enolase-6-PGA/PEP 分子名称: (2R)-2-(phosphonooxy)propanoic acid, (2R)-3-oxo-2-(phosphonooxy)propanoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. 登録日 2011-11-08 公開日 2012-08-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity. J.Inorg.Biochem., 111, 2012
6QKC	GluA1/2 In complex with auxiliary subunit gamma-8 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, Glutamate receptor 1, ... 著者 Herguedas, B, Garcia-Nafria, J, Greger, I.G. 登録日 2019-01-28 公開日 2019-03-27 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP gamma 8. Science, 364, 2019
1MAB	RAT LIVER F1-ATPASE 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Bianchet, M.A, Amzel, L.M. 登録日 1998-08-06 公開日 1998-09-30 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The 2.8-A structure of rat liver F1-ATPase: configuration of a critical intermediate in ATP synthesis/hydrolysis. Proc.Natl.Acad.Sci.USA, 95, 1998
6QCA	Ovine respiratory complex I FRC open class 5 分子名称: Acyl carrier protein, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... 著者 Letts, J.A, Sazanov, L.A. 登録日 2018-12-27 公開日 2019-08-21 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk. Mol.Cell, 75, 2019
6QC3	Ovine respiratory supercomplex I+III2 open class 1 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ... 著者 Letts, J.A, Sazanov, L.A. 登録日 2018-12-26 公開日 2019-08-21 最終更新日 2021-06-02 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk. Mol.Cell, 75, 2019
4OB4	Structure of the S. venezulae BldD DNA-binding domain 分子名称: Putative DNA-binding protein 著者 schumacher, M.A, Tschowri, N, Buttner, M, Brennan, R. 登録日 2014-01-06 公開日 2014-11-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development. Cell(Cambridge,Mass.), 158, 2014
6QDS	Crystal structure of 14-3-3sigma in complex with a PAK6 pT99 phosphopeptide stabilized by semi-synthetic fusicoccane FC-NCPC 分子名称: 14-3-3 protein sigma, CHLORIDE ION, FC-NCPC, ... 著者 Andrei, S.A, Kaplan, A, Fournier, A.E, Ottman, C. 登録日 2019-01-02 公開日 2020-01-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth. Cell Chem Biol, 27, 2020
7LIR	Structure of the invertebrate ALK GRD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor homolog scd-2, ... 著者 Stayrook, S, Li, T, Klein, D.E. 登録日 2021-01-27 公開日 2021-11-24 最終更新日 2021-12-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for ligand reception by anaplastic lymphoma kinase. Nature, 600, 2021
7LS0	Structure of the Human ALK GRD bound to AUG 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor fused with ALK and LTK ligand 2, CITRIC ACID 著者 Stayrook, S, Li, T, Klein, D.E. 登録日 2021-02-17 公開日 2021-11-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Structural basis for ligand reception by anaplastic lymphoma kinase. Nature, 600, 2021
4OFD	Crystal Structure of mouse Neph1 D1-D2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Kin of IRRE-like protein 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Ozkan, E, Garcia, K.C. 登録日 2014-01-14 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.94 Å) 主引用文献 Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis. Cell(Cambridge,Mass.), 156, 2014
3UGQ	Crystal structure of the apo form of the yeast mitochondrial threonyl-tRNA synthetase determined at 2.1 Angstrom resolution 分子名称: POTASSIUM ION, SULFATE ION, Threonyl-tRNA synthetase, ... 著者 Peterson, K.M, Ling, J, Simonovic, I, Cho, C, Soll, D, Simonovic, M. 登録日 2011-11-02 公開日 2012-02-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment. Proc.Natl.Acad.Sci.USA, 109, 2012
7LTT	SAMHD1(113-626) H206R D207N R366C 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, MAGNESIUM ION 著者 Temple, J.T, Bowen, N.E. 登録日 2021-02-20 公開日 2021-11-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins. J.Biol.Chem., 297, 2021
7LU5	SAMHD1(113-626) H206R D207N R366H 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 著者 Temple, J.T, Bowen, N.E. 登録日 2021-02-20 公開日 2021-11-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.57 Å) 主引用文献 Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins. J.Biol.Chem., 297, 2021
3UFX	Thermus aquaticus succinyl-CoA synthetase in complex with GDP-Mn2+ 分子名称: GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, Succinyl-CoA synthetase beta subunit, ... 著者 Fraser, M.E. 登録日 2011-11-01 公開日 2012-06-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Biochemical and structural characterization of the GTP-preferring succinyl-CoA synthetase from Thermus aquaticus. Acta Crystallogr.,Sect.D, 68, 2012
7LRZ	Structure of the Human ALK GRD 分子名称: ALK tyrosine kinase receptor 著者 Stayrook, S, Li, T, Klein, D.E. 登録日 2021-02-17 公開日 2021-11-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structural basis for ligand reception by anaplastic lymphoma kinase. Nature, 600, 2021
6QLG	Crystal structure of AnUbiX (PadA1) in complex with FMN and dimethylallyl pyrophosphate 分子名称: DI(HYDROXYETHYL)ETHER, DIMETHYLALLYL DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, ... 著者 Marshall, S.A, Payne, K.A.P, Leys, D. 登録日 2019-02-01 公開日 2019-06-05 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The UbiX flavin prenyltransferase reaction mechanism resembles class I terpene cyclase chemistry. Nat Commun, 10, 2019
6QLK	Crystal structure of F181H UbiX in complex with prFMN 分子名称: 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, Flavin prenyltransferase UbiX, PHOSPHATE ION, ... 著者 Marshall, S.A, Leys, D. 登録日 2019-02-01 公開日 2019-06-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 The UbiX flavin prenyltransferase reaction mechanism resembles class I terpene cyclase chemistry. Nat Commun, 10, 2019
7QQ7	Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with an inhibitor at partial occupancy with PEG 分子名称: ACETATE ION, BROMIDE ION, CHLORIDE ION, ... 著者 Snee, M, Levy, C, Kavanagh, M. 登録日 2022-01-06 公開日 2023-01-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with an inhibitor at partial occupancy with PEG To Be Published
4OI9	Crystal Structure of ICAM-5 D1-D4 ectodomain fragment, Space Group P21 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Recacha, R, Jimenez, D, Tian, L, Barredo, R, Ghamberg, C, Casasnovas, J.M. 登録日 2014-01-19 公開日 2014-07-16 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of an ICAM-5 ectodomain fragment show electrostatic-based homophilic adhesions. Acta Crystallogr.,Sect.D, 70, 2014

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