PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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7MCD	Crystal structure of an AI-designed TIM-barrel F15C 分子名称: AI-designed TIM-barrel F15C 著者 Mathews, I.I, Anand-Achim, N, Perez, C.P, Huang, P. 登録日 2021-04-02 公開日 2022-01-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Protein sequence design with a learned potential. Nat Commun, 13, 2022
7MSQ	Complex between the Fab arm of AB-3467 and the SARS-CoV-2 receptor binding domain (RBD) 分子名称: AB-3467 Fab Heavy Chain, AB-3467 Fab Light Chain, CHLORIDE ION, ... 著者 Langley, D.B, Christ, D. 登録日 2021-05-12 公開日 2022-01-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability. Immunity, 54, 2021
7MLP	Crystal structure of ricin A chain in complex with 5-(2,6-dimethylphenyl)thiophene-2-carboxylic acid 分子名称: 1,2-ETHANEDIOL, 5-(2,6-dimethylphenyl)thiophene-2-carboxylic acid, Ricin, ... 著者 Harijan, R.K, Li, X.P, Cao, B, Augeri, D, Bonanno, J.B, Almo, S.C, Tumer, N.E, Schramm, V.L. 登録日 2021-04-28 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Synthesis and Structural Characterization of Ricin Inhibitors Targeting Ribosome Binding Using Fragment-Based Methods and Structure-Based Design. J.Med.Chem., 64, 2021
7MLN	Crystal structure of ricin A chain in complex with 5-(o-tolyl)thiophene-2-carboxylic acid 分子名称: 5-(2-methylphenyl)thiophene-2-carboxylic acid, GLYCEROL, Ricin 著者 Harijan, R.K, Li, X.P, Cao, B, Augeri, D, Bonanno, J.B, Almo, S.C, Tumer, N.E, Schramm, V.L. 登録日 2021-04-28 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Synthesis and Structural Characterization of Ricin Inhibitors Targeting Ribosome Binding Using Fragment-Based Methods and Structure-Based Design. J.Med.Chem., 64, 2021
6XRB	Crystal structure of SciW from Salmonella typhimurium 分子名称: SciW, TRIETHYLENE GLYCOL 著者 Sachar, K, Ahmad, S, Whitney, J.C, Prehna, G. 登録日 2020-07-11 公開日 2020-12-30 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones. Elife, 9, 2020
4G0Y	Crystal structure of Arabidopsis AGO1 in complex with AMP 分子名称: ADENOSINE MONOPHOSPHATE, Protein argonaute 1 著者 Frank, F, Hauver, J, Sonenberg, N, Nagar, B. 登録日 2012-07-10 公開日 2012-07-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs. Embo J., 31, 2012
3UQ9	Adenosine kinase from Schistosoma mansoni in complex with tubercidin 分子名称: '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, Adenosine kinase, putative, ... 著者 Romanello, L, Cassago, A, Bachega, F.R, Garatt, R.C, DeMarco, R, Pereira, H.M. 登録日 2011-11-19 公開日 2012-10-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.343 Å) 主引用文献 Adenosine kinase from Schistosoma mansoni: structural basis for the differential incorporation of nucleoside analogues. Acta Crystallogr.,Sect.D, 69, 2013
7MLO	Crystal structure of ricin A chain in complex with 5-mesitylthiophene-2-carboxylic acid 分子名称: 1,2-ETHANEDIOL, 5-(2,4,6-trimethylphenyl)thiophene-2-carboxylic acid, Ricin, ... 著者 Harijan, R.K, Li, X.P, Cao, B, Augeri, D, Bonanno, J.B, Almo, S.C, Tumer, N.E, Schramm, V.L. 登録日 2021-04-28 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Synthesis and Structural Characterization of Ricin Inhibitors Targeting Ribosome Binding Using Fragment-Based Methods and Structure-Based Design. J.Med.Chem., 64, 2021
6HV0	IRE1 kinase/RNase in complex with imidazo[1,2-b]pyridazin-8-amine compound 33 分子名称: 6-chloranyl-3-(2~{H}-indazol-5-yl)-~{N}-propan-2-yl-imidazo[1,2-b]pyridazin-8-amine, Serine/threonine-protein kinase/endoribonuclease IRE1 著者 Bayliss, R, Bhatia, C, Collins, I. 登録日 2018-10-09 公開日 2019-02-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 Binding to an Unusual Inactive Kinase Conformation by Highly Selective Inhibitors of Inositol-Requiring Enzyme 1 alpha Kinase-Endoribonuclease. J.Med.Chem., 62, 2019
7MLT	Crystal structure of ricin A chain in complex with 5-(2-ethylphenyl)thiophene-2-carboxylic acid 分子名称: 1,2-ETHANEDIOL, 5-(2-ethylphenyl)thiophene-2-carboxylic acid, CHLORIDE ION, ... 著者 Harijan, R.K, Li, X.P, Cao, B, Augeri, D, Bonanno, J.B, Almo, S.C, Tumer, N.E, Schramm, V.L. 登録日 2021-04-29 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Synthesis and Structural Characterization of Ricin Inhibitors Targeting Ribosome Binding Using Fragment-Based Methods and Structure-Based Design. J.Med.Chem., 64, 2021
6X74	Rev1 Mg2+-facilitated Product Complex with no monophosphates 分子名称: CHLORIDE ION, DNA (5'-D(*GP*GP*GP*GP*TP*GP*TP*GP*GP*TP*AP*GP*C*)-3'), DNA (5'-D(P*AP*TP*CP*GP*CP*TP*AP*CP*CP*AP*CP*AP*CP*CP*CP*C)-3'), ... 著者 Weaver, T.M, Freudenthal, B.D. 登録日 2020-05-29 公開日 2020-09-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Visualizing Rev1 catalyze protein-template DNA synthesis. Proc.Natl.Acad.Sci.USA, 117, 2020
6X7D	BRD4 Bromodomain 1 in complex with multi-action inhibitor SF2523P 分子名称: 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(piperazin-1-yl)-7H-thieno[3,2-b]pyran-7-one, Bromodomain-containing protein 4 著者 Vann, K.R, Kutateladze, T.G. 登録日 2020-05-29 公開日 2020-08-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Design of thienopyranone-based BET inhibitors that bind multiple synthetic lethality targets. Sci Rep, 10, 2020
1MVW	MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE 分子名称: RABBIT SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL; LIGHT CHAIN, ... 著者 Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A. 登録日 2002-09-26 公開日 2002-11-20 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (70 Å) 主引用文献 Molecular Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle J.STRUCT.BIOL., 138, 2002
7MDJ	The structure of KcsA in complex with a synthetic Fab 分子名称: Fab heavy chain, Fab light chain, POTASSIUM ION, ... 著者 Rohaim, A, Slezak, T, Blackowicz, L, Kossiakoff, A, Roux, B. 登録日 2021-04-05 公開日 2022-02-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels. J.Gen.Physiol., 154, 2022
3GPL	Crystal structure of the ternary complex of RecD2 with DNA and ADPNP 分子名称: 5'-D(*T*TP*TP*TP*TP*TP*TP*T)-3', Exodeoxyribonuclease V, subunit RecD, ... 著者 Saikrishnan, K, Cook, N, Wigley, D.B. 登録日 2009-03-23 公開日 2009-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Mechanistic basis of 5'-3' translocation in SF1B helicases. Cell(Cambridge,Mass.), 137, 2009
5KBK	Candida Albicans Superoxide Dismutase 5 (SOD5), E110A Mutant 分子名称: COPPER (I) ION, Cell surface Cu-only superoxide dismutase 5, SULFATE ION 著者 Galaleldeen, A, Peterson, R.L, Villarreal, J, Taylor, A.B, Hart, P.J. 登録日 2016-06-03 公開日 2016-08-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.411 Å) 主引用文献 The Phylogeny and Active Site Design of Eukaryotic Copper-only Superoxide Dismutases. J.Biol.Chem., 291, 2016
7MOJ	Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with a metaphosphate intermediate 分子名称: PHOSPHITE ION, Tyrosine-protein phosphatase DSP1 著者 Wang, H, Shears, S.B. 登録日 2021-05-01 公開日 2022-03-02 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nat Commun, 13, 2022
7MOF	Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with 6-diphosphoinositol 1,2,3,4,5-pentakisphosphate 6-InsP7 分子名称: (1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, INOSITOL HEXAKISPHOSPHATE, Tyrosine-protein phosphatase DSP1 著者 Wang, H, Shears, S.B. 登録日 2021-05-01 公開日 2022-03-02 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nat Commun, 13, 2022
7MOM	Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) in complex with a metaphosphate intermediate 分子名称: BETA-MERCAPTOETHANOL, PHOSPHITE ION, Tyrosine-protein phosphatase DSP1 著者 Wang, H, Shears, S.B. 登録日 2021-05-01 公開日 2022-03-02 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nat Commun, 13, 2022
7MOE	Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1)Cys150Ser in complex with 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate (5-InsP7) 分子名称: (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, Tyrosine-protein phosphatase DSP1 著者 Wang, H, Shears, S.B. 登録日 2021-05-01 公開日 2022-03-02 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nat Commun, 13, 2022
6XGX	ISCth4 transposase, strand transfer complex 1, STC1 分子名称: DNA (21-MER), DNA (25-MER), DNA (47-MER), ... 著者 Kosek, D, Dyda, F. 登録日 2020-06-18 公開日 2020-10-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition. Embo J., 40, 2021
7MOK	Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) in Complex with Phosphate in Conformation A (Pi(A)) 分子名称: BETA-MERCAPTOETHANOL, PHOSPHATE ION, Tyrosine-protein phosphatase DSP1 著者 Wang, H, Shears, S.B. 登録日 2021-05-01 公開日 2022-03-02 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nat Commun, 13, 2022
7MOI	Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with Phenyl Phosphate 分子名称: PHENYL DIHYDROGEN PHOSPHATE, Tyrosine-protein phosphatase DSP1 著者 Wang, H, Shears, S.B. 登録日 2021-05-01 公開日 2022-03-02 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nat Commun, 13, 2022
7MOL	Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) in complex with phosphate in conformation B (Pi(B)) 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, PHOSPHATE ION, Tyrosine-protein phosphatase DSP1 著者 Wang, H, Shears, S.B. 登録日 2021-05-01 公開日 2022-03-02 最終更新日 2022-05-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nat Commun, 13, 2022
7MOG	Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with 5-PCF2 Am-InsP5, an analogue of 5-InsP7 分子名称: (1,1-difluoro-2-oxo-2-{[(1s,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]amino}ethyl)phosphonic acid, Tyrosine-protein phosphatase DSP1 著者 Wang, H, Shears, S.B. 登録日 2021-05-01 公開日 2022-03-02 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nat Commun, 13, 2022

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