1MMS
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![BU of 1mms by Molmil](/molmil-images/mine/1mms) | Crystal structure of the ribosomal PROTEIN L11-RNA complex | 分子名称: | 23S RIBOSOMAL RNA, CADMIUM ION, MAGNESIUM ION, ... | 著者 | Wimberly, B.T, Guymon, R, Mccutcheon, J.P, White, S.W, Ramakrishnan, V. | 登録日 | 1999-04-14 | 公開日 | 2000-04-17 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | A detailed view of a ribosomal active site: the structure of the L11-RNA complex. Cell(Cambridge,Mass.), 97, 1999
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2AW2
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![BU of 2aw2 by Molmil](/molmil-images/mine/2aw2) | Crystal structure of the human BTLA-HVEM complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B and T lymphocyte attenuator, NICKEL (II) ION, ... | 著者 | Compaan, D.M, Gonzalez, L.C, Tom, I, Loyet, K.M, Eaton, D, Hymowitz, S.G. | 登録日 | 2005-08-31 | 公開日 | 2005-09-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Attenuating Lymphocyte Activity: the crystal structure of the BTLA-HVEM complex J.Biol.Chem., 280, 2005
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2BOA
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![BU of 2boa by Molmil](/molmil-images/mine/2boa) | Human procarboxypeptidase A4. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBOXYPEPTIDASE A4, ... | 著者 | Garcia-Castellanos, R, Bonet-Figueredo, R, Pallares, I, Ventura, S, Aviles, F.X, Vendrell, J, Gomis-Ruth, F.X. | 登録日 | 2005-04-08 | 公開日 | 2005-12-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Detailed Molecular Comparison between the Inhibition Mode of A/B-Type Carboxypeptidases in the Zymogen State and by the Endogenous Inhibitor Latexin. Cell.Mol.Life Sci., 62, 2005
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2G74
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2N02
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![BU of 2n02 by Molmil](/molmil-images/mine/2n02) | Solution structure of the A147T variant of the mitochondrial translocator protein (tspo) in complex with pk11195 | 分子名称: | N-[(2R)-butan-2-yl]-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide, Translocator protein | 著者 | Jaremko, M, Jaremko, L, Giller, K, Becker, S, Zweckstetter, M. | 登録日 | 2015-03-04 | 公開日 | 2015-06-10 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Integrity of the A147T Polymorph of Mammalian TSPO. Chembiochem, 16, 2015
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3TTJ
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![BU of 3ttj by Molmil](/molmil-images/mine/3ttj) | Crystal Structure of JNK3 complexed with CC-359, a JNK inhibitor for the prevention of ischemia-reperfusion injury | 分子名称: | 9-cyclopentyl-N~8~-(2-fluorophenyl)-N~2~-(4-methoxyphenyl)-9H-purine-2,8-diamine, Mitogen-activated protein kinase 10 | 著者 | Plantevin-Krenitsky, V, Delgado, M, Nadolny, L, Sahasrabudhe, K, Ayala, S, Clareen, S, Hilgraf, R, Albers, R, Kois, A, Hughes, K, Wright, J, Nowakowski, J, Sudbeck, E, Ghosh, S, Bahmanyar, S, Chamberlain, P, Muir, J, Cathers, B.E, Giegel, D, Xu, L, Celeridad, M, Moghaddam, M, Khatsenko, O, Omholt, P, Katz, J, Pai, S, Fan, R, Tang, Y, Shirley, M.A, Benish, B, Blease, K, Raymon, H, Bhagwat, S, Bennett, B, Satoh, Y. | 登録日 | 2011-09-14 | 公開日 | 2012-01-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Aminopurine based JNK inhibitors for the prevention of ischemia reperfusion injury. Bioorg.Med.Chem.Lett., 22, 2012
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3U30
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![BU of 3u30 by Molmil](/molmil-images/mine/3u30) | Crystal structure of a linear-specific Ubiquitin fab bound to linear ubiquitin | 分子名称: | Heavy chain Fab, Light chain Fab, linear di-ubiquitin | 著者 | Matsumoto, M.L, Dong, K.C, Yu, C, Phu, L, Gao, X, Hannoush, R.N, Hymowitz, S.G, Kirkpatrick, D.S, Dixit, V.M, Kelley, R.F. | 登録日 | 2011-10-04 | 公開日 | 2012-01-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.428 Å) | 主引用文献 | Engineering and structural characterization of a linear polyubiquitin-specific antibody. J.Mol.Biol., 418, 2012
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3TCQ
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![BU of 3tcq by Molmil](/molmil-images/mine/3tcq) | Crystal Structure of matrix protein VP40 from Ebola virus Sudan | 分子名称: | Matrix protein VP40 | 著者 | Clifton, M.C, Edwards, T.E, Anderson, V, Atkins, K, Raymond, A, Saphire, E.O, Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2011-08-09 | 公開日 | 2012-10-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | High-resolution Crystal Structure of Dimeric VP40 From Sudan ebolavirus. J Infect Dis, 212 Suppl 2, 2015
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3TTI
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![BU of 3tti by Molmil](/molmil-images/mine/3tti) | Crystal Structure of JNK3 complexed with CC-930, an orally active anti-fibrotic JNK inhibitor | 分子名称: | GLYCEROL, Mitogen-activated protein kinase 10, trans-4-({9-[(3S)-tetrahydrofuran-3-yl]-8-[(2,4,6-trifluorophenyl)amino]-9H-purin-2-yl}amino)cyclohexanol | 著者 | Plantevin-Krenitsky, V, Nadolny, L, Delgado, M, Ayala, L, Clareen, S, Hilgraf, R, Albers, R, Hegde, S, D'Sidocky, N, Sapienza, J, Wright, J, McCarrick, M, Bahmanyar, S, Chamberlain, P, Delker, S.L, Muir, J, Giegel, D, Xu, L, Celeridad, M, Lachowitzer, J, Bennett, B, Moghaddam, M, Khatsenko, O, Katz, J, Fan, R, Bai, A, Tang, Y, Shirley, M.A, Benish, B, Bodine, T, Blease, K, Raymon, H, Cathers, B.E, Satoh, Y. | 登録日 | 2011-09-14 | 公開日 | 2012-02-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor. Bioorg.Med.Chem.Lett., 22, 2012
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3UW5
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![BU of 3uw5 by Molmil](/molmil-images/mine/3uw5) | Crystal structure of the BIR domain of MLIAP bound to GDC0152 | 分子名称: | Baculoviral IAP repeat-containing protein 7, Baculoviral IAP repeat-containing protein 4, GDC-0152, ... | 著者 | Maurer, B, Hymowitz, S.G. | 登録日 | 2011-11-30 | 公開日 | 2012-02-22 | 最終更新日 | 2017-08-02 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152). J.Med.Chem., 55, 2012
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4HW1
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![BU of 4hw1 by Molmil](/molmil-images/mine/4hw1) | Multiple Crystal structures of an all-AT DNA dodecamer stabilized by weak interactions. | 分子名称: | DNA (5'-D(*AP*AP*TP*AP*AP*AP*TP*TP*TP*AP*TP*T)-3'), MAGNESIUM ION | 著者 | Acosta-Reyes, F, Subirana, J.A, Pous, J, Condom, N, Malinina, L, Campos, J.L. | 登録日 | 2012-11-07 | 公開日 | 2013-11-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Polymorphic crystal structures of an all-AT DNA dodecamer. Biopolymers, 103, 2015
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4J2I
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![BU of 4j2i by Molmil](/molmil-images/mine/4j2i) | Multiple crystal structures of an all-AT DNA dodecamer stabilized by weak interactions | 分子名称: | 5'-D(*AP*AP*TP*AP*AP*AP*TP*TP*TP*AP*TP*T)-3' | 著者 | Acosta-Reyes, F.J, Subirana, J.A, Pous, J, Sanchez, R, Condom, N, Baldini, R, Malinina, L, Campos, J.L. | 登録日 | 2013-02-04 | 公開日 | 2014-02-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Polymorphic crystal structures of an all-AT DNA dodecamer. Biopolymers, 103, 2015
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2BYH
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![BU of 2byh by Molmil](/molmil-images/mine/2byh) | 3-(5-chloro-2,4-dihydroxyphenyl)-pyrazole-4-carboxamides as Inhibitors of the Hsp90 Molecular Chaperone | 分子名称: | HEAT SHOCK PROTEIN HSP90-ALPHA, N-(4-ACETYLPHENYL)-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE | 著者 | Brough, P.A, Barril, X, Beswick, M, Dymock, B.W, Drysdale, M.J, Wright, L, Grant, K, Massey, A, Surgenor, A, Workman, P. | 登録日 | 2005-08-02 | 公開日 | 2005-10-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | 3-(5-Chloro-2,4-Dihydroxyphenyl)-Pyrazole-4-Carboxamides as Inhibitors of the Hsp90 Molecular Chaperone. Bioorg.Med.Chem.Lett., 15, 2005
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2N07
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![BU of 2n07 by Molmil](/molmil-images/mine/2n07) | Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic alpha-Conotoxin Vc1.1 | 分子名称: | Alpha-conotoxin Vc1A | 著者 | Yu, R, Seymour, V, Berecki, G, Jia, X, Akcan, M, Adams, D, Kaas, Q, Craik, D. | 登録日 | 2015-03-04 | 公開日 | 2016-04-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic alpha-Conotoxin Vc1.1. To be Published
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2BYI
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![BU of 2byi by Molmil](/molmil-images/mine/2byi) | 3-(5-chloro-2,4-dihydroxyphenyl)-pyrazole-4-carboxamides as Inhibitors of the Hsp90 Molecular Chaperone | 分子名称: | 3-(5-CHLORO-2,4-DIHYDROXY-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 4-SULFAMOYL-BENZYLAMIDE, HEAT SHOCK PROTEIN HSP90-ALPHA | 著者 | Brough, P.A, Barril, X, Beswick, M, Dymock, B.W, Drysdale, M.J, Wright, L, Grant, K, Massey, A, Surgenor, A, Workman, P. | 登録日 | 2005-08-02 | 公開日 | 2005-10-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | 3-(5-Chloro-2,4-Dihydroxyphenyl)-Pyrazole-4-Carboxamides as Inhibitors of the Hsp90 Molecular Chaperone. Bioorg.Med.Chem.Lett., 15, 2005
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2CCS
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![BU of 2ccs by Molmil](/molmil-images/mine/2ccs) | HUMAN HSP90 WITH 4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-3-YL)- BENZENE-1,2-DIOL | 分子名称: | 4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL, HEAT SHOCK PROTEIN HSP-90 ALPHA | 著者 | Barril, X, Beswick, M.C, Collier, A, Drysdale, M.J, Dymock, B.W, Fink, A, Grant, K, Howes, R, Jordan, A.M, Massey, A, Surgenor, A, Wayne, J, Workman, P, Wright, L. | 登録日 | 2006-01-18 | 公開日 | 2006-02-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | 4-Amino derivatives of the Hsp90 inhibitor CCT018159. Bioorg. Med. Chem. Lett., 16, 2006
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2OT5
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1CQ4
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![BU of 1cq4 by Molmil](/molmil-images/mine/1cq4) | |
4AIE
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![BU of 4aie by Molmil](/molmil-images/mine/4aie) | Structure of glucan-1,6-alpha-glucosidase from Lactobacillus acidophilus NCFM | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLUCAN 1,6-ALPHA-GLUCOSIDASE, ... | 著者 | Fredslund, F, Navarro Poulsen, J.C, Lo Leggio, L. | 登録日 | 2012-02-09 | 公開日 | 2012-08-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Enzymology and Structure of the Gh13_31 Glucan 1,6-Alpha-Glucosidase that Confers Isomaltooligosaccharide Utilization in the Probiotic Lactobacillus Acidophilus Ncfm. J.Bacteriol., 194, 2012
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2CCU
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![BU of 2ccu by Molmil](/molmil-images/mine/2ccu) | HUMAN HSP90 WITH 4-CHLORO-6-(4-(4-(4-METHANESULPHONYL-BENZYL)- PIERAZIN-1-YL)-1H-PYRAZOL-3-YL)-BENZENE-1,3-DIOL | 分子名称: | 4-CHLORO-6-(4-{4-[4-(METHYLSULFONYL)BENZYL]PIPERAZIN-1-YL}-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL, HEAT SHOCK PROTEIN HSP-90 ALPHA | 著者 | Barril, X, Beswick, M.C, Collier, A, Drysdale, M.J, Dymock, B.W, Fink, A, Grant, K, Howes, R, Jordan, A.M, Massey, A, Surgenor, A, Wayne, J, Workman, P, Wright, L. | 登録日 | 2006-01-18 | 公開日 | 2006-02-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | 4-Amino derivatives of the Hsp90 inhibitor CCT018159. Bioorg. Med. Chem. Lett., 16, 2006
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2CCT
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![BU of 2cct by Molmil](/molmil-images/mine/2cct) | HUMAN HSP90 WITH 5-(5-CHLORO-2,4-DIHYDROXY-PHENYL)-4-PIPERAZIN-1-YL- 2H-PYRAZOLE-3-CARBOXYLIC ACID ETHYLAMIDE | 分子名称: | 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE, HEAT SHOCK PROTEIN HSP-90 ALPHA | 著者 | Barril, X, Beswick, M.C, Collier, A, Drysdale, M.J, Dymock, B.W, Fink, A, Grant, K, Howes, R, Jordan, A.M, Massey, A, Surgenor, A, Wayne, J, Workman, P, Wright, L. | 登録日 | 2006-01-18 | 公開日 | 2006-02-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | 4-Amino derivatives of the Hsp90 inhibitor CCT018159. Bioorg. Med. Chem. Lett., 16, 2006
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2EPH
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![BU of 2eph by Molmil](/molmil-images/mine/2eph) | Crystal structure of fructose-bisphosphate aldolase from Plasmodium falciparum in complex with TRAP-tail determined at 2.7 angstrom resolution | 分子名称: | Fructose-bisphosphate aldolase, PbTRAP | 著者 | Bosch, J, Buscaglia, C.A, Krumm, B, Cardozo, T, Nussenzweig, V, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | 登録日 | 2007-03-30 | 公開日 | 2007-04-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2PC4
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![BU of 2pc4 by Molmil](/molmil-images/mine/2pc4) | Crystal structure of fructose-bisphosphate aldolase from Plasmodium falciparum in complex with TRAP-tail determined at 2.4 angstrom resolution | 分子名称: | Fructose-bisphosphate aldolase, PbTRAP | 著者 | Bosch, J, Buscaglia, C.A, Krumm, B, Cardozo, T, Nussenzweig, V, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | 登録日 | 2007-03-29 | 公開日 | 2007-04-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2FMN
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![BU of 2fmn by Molmil](/molmil-images/mine/2fmn) | Ala177Val mutant of E. coli Methylenetetrahydrofolate Reductase complex with LY309887 | 分子名称: | 5,10-methylenetetrahydrofolate reductase, FLAVIN-ADENINE DINUCLEOTIDE, N-[(5-{2-[(6R)-2-AMINO-4-OXO-3,4,5,6,7,8-HEXAHYDROPYRIDO[2,3-D]PYRIMIDIN-6-YL]ETHYL}-2-THIENYL)CARBONYL]-L-GLUTAMIC ACID | 著者 | Pejchal, R, Campbell, E, Guenther, B.D, Lennon, B.W, Matthews, R.G, Ludwig, M.L. | 登録日 | 2006-01-09 | 公開日 | 2006-04-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural Perturbations in the Ala -> Val Polymorphism of Methylenetetrahydrofolate Reductase: How Binding of Folates May Protect against Inactivation Biochemistry, 45, 2006
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2FMO
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![BU of 2fmo by Molmil](/molmil-images/mine/2fmo) | Ala177Val mutant of E. coli Methylenetetrahydrofolate Reductase | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5,10-methylenetetrahydrofolate reductase, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Pejchal, R, Campbell, E, Guenther, B.D, Lennon, B.W, Matthews, R.G, Ludwig, M.L. | 登録日 | 2006-01-09 | 公開日 | 2006-04-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Perturbations in the Ala -> Val Polymorphism of Methylenetetrahydrofolate Reductase: How Binding of Folates May Protect against Inactivation Biochemistry, 45, 2006
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