5J8V
 
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8U89
 | | The structure of the PP2A-B56Delta holoenzyme mutant - E197K | | 分子名称: | MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... | | 著者 | Wu, C.G, Xing, Y. | | 登録日 | 2023-09-16 | | 公開日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | B56 delta long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations.
Proc.Natl.Acad.Sci.USA, 121, 2024
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1UUE
 | | a-SPECTRIN SH3 DOMAIN (V44T, D48G MUTANT) | | 分子名称: | SPECTRIN ALPHA CHAIN | | 著者 | Vega, M.C, Fernandez, A, Wilmanns, M, Serrano, L. | | 登録日 | 2003-12-18 | | 公開日 | 2004-02-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Solvation in Protein Folding Analysis: Combination of Theoretical and Experimental Approaches
Proc.Natl.Acad.Sci.USA, 101, 2004
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1W2F
 | | Human Inositol (1,4,5)-trisphosphate 3-kinase substituted with selenomethionine | | 分子名称: | INOSITOL-TRISPHOSPHATE 3-KINASE A, SULFATE ION | | 著者 | Gonzalez, B, Schell, M.J, Irvine, R.F, Williams, R.L. | | 登録日 | 2004-07-01 | | 公開日 | 2004-09-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of a Human Inositol 1,4,5-Trisphosphate 3-Kinase; Substrate Binding Reveals Why It is not a Phosphoinositide 3-Kinase
Mol.Cell, 15, 2004
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1WGP
 | | Solution structure of the cNMP-binding domain from Arabidopsis thaliana cyclic nucleotide-regulated ion channel | | 分子名称: | Probable cyclic nucleotide-gated ion channel 6 | | 著者 | Chikayama, E, Nameki, N, Kigawa, T, Koshiba, S, Inoue, M, Tomizawa, T, Kobayashi, N, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-05-28 | | 公開日 | 2004-11-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the cNMP-binding domain from Arabidopsis thaliana cyclic nucleotide-regulated ion channel
To be Published
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1WKU
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1WY9
 | | Crystal structure of microglia-specific protein, Iba1 | | 分子名称: | Allograft inflammatory factor 1, CALCIUM ION | | 著者 | Yamada, M, Imai, Y, Kohsaka, S, Kamitori, S. | | 登録日 | 2005-02-09 | | 公開日 | 2006-02-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | X-ray Structures of the Microglia/Macrophage-specific Protein Iba1 from Human and Mouse Demonstrate Novel Molecular Conformation Change Induced by Calcium binding
J.Mol.Biol., 364, 2006
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1WAA
 | | IG27 protein domain | | 分子名称: | TITIN, ZINC ION | | 著者 | Vega, M.C, Valencia, L, Zou, P, Wilmanns, M. | | 登録日 | 2004-10-25 | | 公開日 | 2006-07-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mechanical Network in Titin Immunoglobulin from Force Distribution Analysis.
Plos Comput.Biol., 5, 2009
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1W7J
 | | Crystal Structure Of Myosin V Motor With Essential Light Chain + ADP-BeFx - Near Rigor | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Coureux, P.-D, Sweeney, H.L, Houdusse, A. | | 登録日 | 2004-09-03 | | 公開日 | 2005-02-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three Myosin V Structures Delineate Essential Features of Chemo-Mechanical Transduction
Embo J., 23, 2004
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1WAO
 | | PP5 structure | | 分子名称: | MANGANESE (II) ION, SERINE/THREONINE PROTEIN PHOSPHATASE 5 | | 著者 | Barford, D. | | 登録日 | 2004-10-27 | | 公開日 | 2005-02-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Molecular Basis for Tpr Domain-Mediated Regulation of Protein Phosphatase 5
Embo J., 24, 2005
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1VHR
 | | HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE VHR, SULFATE ION | | 著者 | Yuvaniyama, J, Denu, J.M, Dixon, J.E, Saper, M.A. | | 登録日 | 1996-02-20 | | 公開日 | 1996-06-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the dual specificity protein phosphatase VHR.
Science, 272, 1996
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4I5N
 | | Structural mechanism of trimeric PP2A holoenzyme involving PR70: insight for Cdc6 dephosphorylation | | 分子名称: | CALCIUM ION, MANGANESE (II) ION, Microcystin-LR (MCLR) bound form, ... | | 著者 | Wlodarchak, N, Satyshur, K.A, Guo, F, Xing, Y. | | 登録日 | 2012-11-28 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Cell Res., 23, 2013
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4IMJ
 | | Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine-tune the Phosphatase Activity of Ssu72 | | 分子名称: | CG14216, CTD, PHOSPHATE ION, ... | | 著者 | Luo, Y, Yogesha, S.D, Zhang, Y. | | 登録日 | 2013-01-03 | | 公開日 | 2013-08-07 | | 最終更新日 | 2013-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Novel Modifications on C-terminal Domain of RNA Polymerase II Can Fine-tune the Phosphatase Activity of Ssu72.
Acs Chem.Biol., 8, 2013
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4JA9
 | | Rat PP5 apo | | 分子名称: | MAGNESIUM ION, Serine/threonine-protein phosphatase 5 | | 著者 | Haslbeck, V, Helmuth, M, Alte, F, Popowicz, G, Schmidt, W, Weiwad, M, Fischer, G, Gemmecker, G, Sattler, M, Striggow, F, Groll, M, Richter, K. | | 登録日 | 2013-02-18 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism.
Biosci.Rep., 35, 2015
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3SHQ
 | | Crystal Structure of UBLCP1 | | 分子名称: | MAGNESIUM ION, UBLCP1 | | 著者 | Xiao, J, Engel, J.L. | | 登録日 | 2011-06-16 | | 公開日 | 2011-10-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3V4Y
 | | Crystal Structure of the first Nuclear PP1 holoenzyme | | 分子名称: | GLYCEROL, MANGANESE (II) ION, Nuclear inhibitor of protein phosphatase 1, ... | | 著者 | Page, R, Peti, W, O'Connell, N.E, Nichols, S. | | 登録日 | 2011-12-15 | | 公開日 | 2012-10-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.098 Å) | | 主引用文献 | The Molecular Basis for Substrate Specificity of the Nuclear NIPP1:PP1 Holoenzyme.
Structure, 20, 2012
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4JS9
 | | Structural Characterization of Inducible Nitric Oxide Synthase Substituted With Mesoheme | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, Mesoheme, Nitric oxide synthase, ... | | 著者 | Hannibal, L, Page, R.C, Bolisetty, K, Yu, Z, Misra, S, Stuehr, D.J. | | 登録日 | 2013-03-22 | | 公開日 | 2014-04-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.784 Å) | | 主引用文献 | Kinetic and Structural Characterization of Inducible Nitric Oxide Synthase Substituted With Mesoheme
To be Published
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6NKK
 | | Structure of PhqE Reductase/Diels-Alderase from Penicillium fellutanum in complex with NADP+ and premalbrancheamide | | 分子名称: | (5aS,12aS,13aS)-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7,6-b]carbazol-14-one, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short chain dehydrogenase | | 著者 | Newmister, S.A, Dan, Q, Smith, J.L, Sherman, D.H. | | 登録日 | 2019-01-07 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | | 主引用文献 | Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase.
Nat.Chem., 11, 2019
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6NKM
 | | Structure of PhqE D166N Reductase/Diels-Alderase from Penicillium fellutanum in complex with NADP+ and substrate | | 分子名称: | 3-{[2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]methyl}-8H-pyrrolo[1,2-a]pyrazin-5-ium-1-olate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short chain dehydrogenase | | 著者 | Newmister, S.A, Dan, Q, Smith, J.L, Sherman, D.H. | | 登録日 | 2019-01-07 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.896 Å) | | 主引用文献 | Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase.
Nat.Chem., 11, 2019
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6NPW
 | | SSu72/Sympk in complex with Ser2/Ser5 phosphorylated peptide | | 分子名称: | PHOSPHATE ION, Ser2/Ser5 phosphorylated peptide, Ssu72 ortholog, ... | | 著者 | Irani, S, Zhang, Y. | | 登録日 | 2019-01-18 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.486 Å) | | 主引用文献 | Structural determinants for accurate dephosphorylation of RNA polymerase II by its cognate C-terminal domain (CTD) phosphatase during eukaryotic transcription.
J.Biol.Chem., 294, 2019
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4JA7
 | | Rat PP5 co-crystallized with P5SA-2 | | 分子名称: | MAGNESIUM ION, Serine/threonine-protein phosphatase 5 | | 著者 | Haslbeck, V, Helmuth, M, Alte, F, Popowicz, G, Schmidt, W, Weiwad, M, Fischer, G, Gemmecker, G, Sattler, M, Striggow, F, Groll, M, Richter, K. | | 登録日 | 2013-02-18 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism.
Biosci.Rep., 35, 2015
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3TAC
 | | Crystal Structure of the Liprin-alpha/CASK complex | | 分子名称: | CHLORIDE ION, Liprin-alpha-2, Peripheral plasma membrane protein CASK, ... | | 著者 | Wei, Z, Zheng, S, Yu, C, Zhang, M. | | 登録日 | 2011-08-03 | | 公開日 | 2011-10-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Liprin-mediated large signaling complex organization revealed by the liprin-alpha/CASK and liprin-alpha/liprin-beta complex structures
Mol.Cell, 43, 2011
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6NKH
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6NTS
 | | Protein Phosphatase 2A (Aalpha-B56alpha-Calpha) holoenzyme in complex with a Small Molecule Activator of PP2A (SMAP) | | 分子名称: | MANGANESE (II) ION, N-[(1R,2R,3S)-2-hydroxy-3-(10H-phenoxazin-10-yl)cyclohexyl]-4-(trifluoromethoxy)benzene-1-sulfonamide, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform, ... | | 著者 | Huang, W, Taylor, D. | | 登録日 | 2019-01-30 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | | 主引用文献 | Selective PP2A Enhancement through Biased Heterotrimer Stabilization.
Cell, 181, 2020
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6NKI
 | | Structure of PhqB Reductase Domain from Penicillium fellutanum | | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NRPS | | 著者 | Dan, Q, Newmister, S.A, Smith, J.L, Sherman, D.H. | | 登録日 | 2019-01-07 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase.
Nat.Chem., 11, 2019
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