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8BGW
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CryoEM structure of quinol-dependent Nitric Oxide Reductase (qNOR) from Alcaligenes xylosoxidans at 2.2 A resolution
分子名称: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, CALCIUM ION, FE (III) ION, ...
著者Flynn, A, Antonyuk, S.V, Eady, R.R, Muench, S.P, Hasnain, S.S.
登録日2022-10-28
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献A 2.2 angstrom cryoEM structure of a quinol-dependent NO Reductase shows close similarity to respiratory oxidases.
Nat Commun, 14, 2023
6YCX
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Plasmodium falciparum Myosin A full-length, pre-powerstroke state
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin A tail domain interacting protein, ...
著者Moussaoui, D, Robblee, J.P, Auguin, D, Krementsova, E.B, Robert-Paganin, J, Trybus, K.M, Houdusse, A.
登録日2020-03-19
公開日2020-11-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.99 Å)
主引用文献Full-length Plasmodium falciparum myosin A and essential light chain PfELC structures provide new anti-malarial targets.
Elife, 9, 2020
4UD4
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Structural Plasticity of Cid1 Provides a Basis for its RNA Terminal Uridylyl Transferase Activity
分子名称: GLYCEROL, POLY(A) RNA POLYMERASE PROTEIN CID1
著者Yates, L.A, Durrant, B.P, Fleurdepine, S, Harlos, K, Norbury, C.J, Gilbert, R.J.C.
登録日2014-12-07
公開日2015-03-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural plasticity of Cid1 provides a basis for its distributive RNA terminal uridylyl transferase activity.
Nucleic Acids Res., 43, 2015
4UD5
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Structural Plasticity of Cid1 Provides a Basis for its RNA Terminal Uridylyl Transferase Activity
分子名称: POLY(A) RNA POLYMERASE PROTEIN CID1
著者Yates, L.A, Durrant, B.P, Fleurdepine, S, Harlos, K, Norbury, C.J, Gilbert, R.J.C.
登録日2014-12-07
公開日2015-03-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Structural Plasticity of Cid1 Provides a Basis for its Distributive RNA Terminal Uridylyl Transferase Activity.
Nucleic Acids Res., 43, 2015
8G3V
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BU of 8g3v by Molmil
N2 neuraminidase of A/Hong_Kong/2671/2019 in complex with 4 FNI19 Fab molecules
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Dang, H.V, Snell, G.
登録日2023-02-08
公開日2023-05-31
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (2.21 Å)
主引用文献A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature, 618, 2023
6YCY
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BU of 6ycy by Molmil
Plasmodium falciparum Myosin A full-length, post-rigor state
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Moussaoui, D, Robblee, J.P, Auguin, D, Krementsova, E.B, Robert-Paganin, J, Trybus, K.M, Houdusse, A.
登録日2020-03-19
公開日2020-11-11
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Full-length Plasmodium falciparum myosin A and essential light chain PfELC structures provide new anti-malarial targets.
Elife, 9, 2020
6YQO
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BU of 6yqo by Molmil
Crystal structure of the first bromodomain of human BRD4 in complex with the dual inhibitor TW12
分子名称: (S)-N1-(4-(2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamido)phenyl)-N8-hydroxyoctanediamide, 1,2-ETHANEDIOL, Bromodomain-containing protein 4
著者Joerger, A.C, Balourdas, D.I, Weiser, T, Chatterjee, D, Knapp, S, Structural Genomics Consortium (SGC)
登録日2020-04-17
公開日2020-05-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma.
Int.J.Cancer, 147, 2020
6WEZ
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BU of 6wez by Molmil
Crystal Structure of Broadly Neutralizing Antibody 3I14-D93N Mutant Bound to the Influenza A H3 Hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hemagglutinin, ...
著者Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A.
登録日2020-04-03
公開日2020-11-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
Nat Commun, 12, 2021
6WF1
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BU of 6wf1 by Molmil
Crystal Structure of Broadly Neutralizing Antibody 3I14 Bound to the Influenza A H10 Hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Hemagglutinin HA2 chain, ...
著者Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A.
登録日2020-04-03
公開日2020-11-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.19 Å)
主引用文献Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
Nat Commun, 12, 2021
4R8W
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BU of 4r8w by Molmil
Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a neutralizing antibody CT149
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of neutralizing antibody CT149, Hemagglutinin, ...
著者Wu, Y, Shi, Y, Qi, J, Gao, G.F.
登録日2014-09-03
公開日2015-08-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.795 Å)
主引用文献A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus
Nat Commun, 6, 2015
7MIQ
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BU of 7miq by Molmil
Crystal structure of a Glutathione S-transferase class Gtt2 of Vibrio parahaemolyticus (VpGSTT2)
分子名称: DI(HYDROXYETHYL)ETHER, Glutathione S-transferase, SULFATE ION
著者Valenzuela-Chavira, I, Serrano-Posada, H, Lopez-Zavala, A.A, Garcia-Orozco, K.D, Sotelo-Mundo, R.R.
登録日2021-04-17
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A Novel Glutathione S -Transferase Gtt2 Class (VpGSTT2) Is Found in the Genome of the AHPND/EMS Vibrio parahaemolyticus Shrimp Pathogen.
Toxins, 13, 2021
4R4U
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BU of 4r4u by Molmil
Crystal structure of acyl-CoA thioesterase tesB from Yersinia pestis in complex with coenzyme A
分子名称: Acyl-CoA thioesterase II, COENZYME A, MALONIC ACID, ...
著者Swarbrick, C.M.D, Forwood, J.K.
登録日2014-08-19
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and functional characterization of TesB from Yersinia pestis reveals a unique octameric arrangement of hotdog domains.
Acta Crystallogr.,Sect.D, 71, 2015
8EB2
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BU of 8eb2 by Molmil
Structure of HLA-A*02:01 in complex with NY-ESO-1 peptide and PA2.1 Fab
分子名称: Beta-2-microglobulin, HLA-A*02:01 alpha chain, NY-ESO-1 peptide, ...
著者Jette, C.A, West, A.P.
登録日2022-08-30
公開日2022-11-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献HLA-A∗02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen.
Mol Ther Oncolytics, 27, 2022
7M57
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BU of 7m57 by Molmil
Crystallographic structure of a primitive orthorhombic crystal form of STMV
分子名称: Coat protein, PHOSPHATE ION, RNA (27-mer), ...
著者McPherson, A.
登録日2021-03-22
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structures of additional crystal forms of Satellite tobacco mosaic virus grown from a variety of salts.
Acta Crystallogr.,Sect.F, 77, 2021
6XCE
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BU of 6xce by Molmil
Structure of the C. botulinum neurotoxin serotype A light chain protease in complex with covalent inhibitor 53
分子名称: (3S)-3-(2,4-dichlorophenyl)-N~1~-hydroxy-N~5~-(3-sulfanylpropyl)pentanediamide, Botulinum neurotoxin type A
著者Tararina, M.A, Allen, K.N.
登録日2020-06-08
公開日2020-09-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Catch and Anchor Approach To Combat Both Toxicity and Longevity of Botulinum Toxin A.
J.Med.Chem., 63, 2020
6XPQ
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BU of 6xpq by Molmil
Human antibody D1 H1-17/H3-14 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2)
分子名称: Hemagglutinin, antibody D1 H1-17/H3-14 light chain, antibody D1 H1-17/H3-14 heavy chain, ...
著者McCarthy, K.R, Harrison, S.C.
登録日2020-07-08
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XPX
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BU of 6xpx by Molmil
Human antibody S1V2-51 in complex with the influenza hemagglutinin head domain of A/Aichi/2/1968 (X-31)(H3N2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BICINE, GLYCEROL, ...
著者McCarthy, K.R, Harrison, S.C.
登録日2020-07-09
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.598 Å)
主引用文献A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XQ4
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BU of 6xq4 by Molmil
Human antibody S8V2-47 in complex with the influenza hemagglutinin head domain of A/Beijing/262/1995(H1N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, antibody S8V2-47 heavy chain, ...
著者McCarthy, K.R, Harrison, S.C.
登録日2020-07-09
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.347 Å)
主引用文献A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XPR
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BU of 6xpr by Molmil
Human antibody D2 H1-1/H3-1 H3 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者McCarthy, K.R, Harrison, S.C, Lee, J.
登録日2020-07-08
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.092 Å)
主引用文献A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6WEX
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BU of 6wex by Molmil
Crystal Structure of Broadly Neutralizing Antibody 3I14-D93N Mutant Bound to the Influenza A H6 Hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Hemagglutinin HA2 chain, ...
著者Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A.
登録日2020-04-03
公開日2020-11-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
Nat Commun, 12, 2021
6WCR
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BU of 6wcr by Molmil
Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule F0045(S)
分子名称: (2,4-dichlorophenyl)[(2S)-2-phenylmorpholin-4-yl]methanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者kadam, R.U, Wilson, I.A.
登録日2020-03-31
公開日2020-08-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WF0
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BU of 6wf0 by Molmil
Crystal Structure of Broadly Neutralizing Antibody 3I14 Bound to the Influenza A H3 Hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A.
登録日2020-04-03
公開日2020-11-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
Nat Commun, 12, 2021
8G30
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BU of 8g30 by Molmil
N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with 4 FNI19 Fab molecules
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FNI19 Fab heavy chain, ...
著者Dang, H.V, Snell, G.
登録日2023-02-06
公開日2023-05-31
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature, 618, 2023
6XP9
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BU of 6xp9 by Molmil
STRUCTURE OF HUMAN PREGNANE X RECEPTOR LIGAND BINDING DOMAIN BOUND TETHERED WITH SRC co-activator peptide IN COMPLEX WITH (S,S)-1
分子名称: (2S)-tert-butoxy[7-(8-fluoro-5-methyl-3,4-dihydro-2H-1-benzopyran-6-yl)-5-methyl-2-phenylpyrazolo[1,5-a]pyrimidin-6-yl]acetic acid, GLYCEROL, Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1 fusion
著者Khan, J.A.
登録日2020-07-08
公開日2020-09-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structure-based amelioration of PXR transactivation in a novel series of macrocyclic allosteric inhibitors of HIV-1 integrase.
Bioorg.Med.Chem.Lett., 30, 2020
7B3A
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BU of 7b3a by Molmil
Crystal structure of PamZ
分子名称: ACETATE ION, ACETYL COENZYME *A, CHLORIDE ION, ...
著者Loll, B, Dang, T, Mainz, A, Suessmuth, R, Wahl, M.C.
登録日2020-11-30
公開日2021-11-10
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Molecular basis of antibiotic self-resistance in a bee larvae pathogen.
Nat Commun, 13, 2022

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