PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

---

6FI3	Crystal structure of ERK2 in complex with an adenosine derivative 分子名称: (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-(azanyloxymethyl)oxolane-3,4-diol, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ... 著者 Gelin, M, Labesse, G. 登録日 2018-01-16 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Crystal structure of ERK2 in complex with an adenosine derivative To be published
5YWA	Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (CTD class 2 at 6.1A) 分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (6.1 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
6FJZ	Crystal structure of ERK2 in complex with an adenosine derivative 分子名称: (2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)-~{N}-prop-2-ynyl-oxolane-2-carboxamide, Mitogen-activated protein kinase 1, SULFATE ION 著者 Gelin, M, Labesse, G. 登録日 2018-01-23 公開日 2019-02-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.864 Å) 主引用文献 Crystal structure of ERK2 in complex with an adenosine derivative To be published
4H9Q	Complex structure 4 of DAXX(E225A)/H3.3(sub5)/H4 分子名称: Death domain-associated protein 6, Histone H3.3, Histone H4, ... 著者 Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J. 登録日 2012-09-24 公開日 2012-10-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out To be Published
6FHU	Crystal structure of BAZ2A PHD zinc finger in complex with H3 3-mer peptide 分子名称: ALA-ARG-TAM, Bromodomain adjacent to zinc finger domain protein 2A, GLYCEROL, ... 著者 Amato, A, Lucas, X, Bortoluzzi, A, Wright, D, Ciulli, A. 登録日 2018-01-15 公開日 2018-03-21 最終更新日 2018-05-02 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach. ACS Chem. Biol., 13, 2018
6FI6	Crystal structure of ERK2 in complex with an adenosine derivative 分子名称: (2~{R},3~{R},4~{S},5~{R})-2-(6-azanyl-8-diazanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ... 著者 Gelin, M, Labesse, G. 登録日 2018-01-17 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of ERK2 in complex with an adenosine derivative To be published
4JMO	Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide 分子名称: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide 著者 Hoh, F, Rouhana, J. 登録日 2013-03-14 公開日 2013-10-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors J.Med.Chem., 56, 2013
5X8N	Crystal structure of mouse importin-alpha1 bound to the nuclear localization signal of Epstein-Barr virus EBNA-LP protein 分子名称: Epstein-Barr nuclear antigen leader protein, Importin subunit alpha-1 著者 Nakada, R, Matsuura, Y. 登録日 2017-03-03 公開日 2017-04-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of importin-alpha bound to the nuclear localization signal of Epstein-Barr virus EBNA-LP protein Protein Sci., 26, 2017
6C1A	MBD2 in complex with methylated DNA 分子名称: Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION, complement to dna strand 1, ... 著者 Liu, K, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2018-01-04 公開日 2018-02-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. J. Biol. Chem., 293, 2018
6C1T	MBD2 in complex with a partially methylated DNA 分子名称: 12-mer DNA, GLYCEROL, Methyl-CpG-binding domain protein 2, ... 著者 Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2018-01-05 公開日 2018-02-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. J. Biol. Chem., 293, 2018
5X5D	Human thymidylate synthase bound with dUMP 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase 著者 Chen, D, Jansson, A, Larsson, A, Nordlund, P. 登録日 2017-02-15 公開日 2017-06-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states J. Biol. Chem., 292, 2017
5XAD	NLIR - LC3B fusion protein 分子名称: Microtubule-associated proteins 1A/1B light chain 3B, Uncharacterised protein 著者 Kwon, D.H, Kim, L, Song, H.K. 登録日 2017-03-12 公開日 2017-07-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 A novel conformation of the LC3-interacting region motif revealed by the structure of a complex between LC3B and RavZ Biochem. Biophys. Res. Commun., 490, 2017
4N3Z	Crystal structure of Rabex-5delta and Rabaptin-5C21 complex 分子名称: PHOSPHATE ION, Rab GTPase-binding effector protein 1, Rab5 GDP/GTP exchange factor 著者 Zhang, Z, Zhang, T, Ding, J. 登録日 2013-10-08 公開日 2014-07-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5 Elife, 3, 2014
6BTI	Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with N-arachidonoylethanolamine (AEA) 分子名称: (5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide, DI(HYDROXYETHYL)ETHER, Retinol-binding protein 2 著者 Silvaroli, J.A, Blaner, W.S, Lodowski, D.T, Golczak, M. 登録日 2017-12-06 公開日 2018-12-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight. Sci Adv, 6, 2020
6C3P	Cryo-EM structure of human KATP bound to ATP and ADP in propeller form 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... 著者 Lee, K.P.K, Chen, J, MacKinnon, R. 登録日 2018-01-10 公開日 2018-01-24 実験手法 ELECTRON MICROSCOPY (5.6 Å) 主引用文献 Molecular structure of human KATP in complex with ATP and ADP. Elife, 6, 2017
4JT3	Crystal Structure of TTK kinase domain with an inhibitor: 400740 分子名称: 1,2-ETHANEDIOL, 2-phenyl-N-[3-(3-sulfamoylphenyl)-2H-indazol-5-yl]acetamide, Dual specificity protein kinase TTK, ... 著者 Qiu, W, Harris-Brandts, M, Feher, M, Awrey, D.E, Chirgadze, N.Y. 登録日 2013-03-22 公開日 2014-03-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of TTK kinase domain with an inhibitor: 400740 To be Published
6FJ0	Crystal structure of ERK2 in complex with an adenosine derivative 分子名称: 5'-deoxy-5'-(prop-2-yn-1-ylamino)adenosine, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ... 著者 Gelin, M, Labesse, G. 登録日 2018-01-19 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.659 Å) 主引用文献 Crystal structure of ERK2 in complex with an adenosine derivative To be published
6FCP	Crystal structure of 14-3-3 sigma in complex with Shroom3 P1244L 分子名称: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... 著者 Leysen, S, Meijer, F.A, Milroy, L.G, Ottmann, C. 登録日 2017-12-20 公開日 2018-03-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Characterization of Coding/Noncoding Variants forSHROOM3in Patients with CKD. J. Am. Soc. Nephrol., 29, 2018
6C05	Mycobacterium tuberculosis RNAP Holo/RbpA in relaxed state 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M. 登録日 2017-12-27 公開日 2018-03-28 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (5.15 Å) 主引用文献 Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife, 7, 2018
5XI2	BRD4 bound with compound Bdi2 分子名称: (3~{R})-4-cyclopropyl-1,3-dimethyl-6-[[(1~{S})-1-(4-methylphenyl)ethyl]amino]-3~{H}-quinoxalin-2-one, Bromodomain-containing protein 4 著者 Xiong, B, Cao, D, Li, Y. 登録日 2017-04-25 公開日 2018-05-02 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.909 Å) 主引用文献 BRD4 bound with compound Bdi2 To Be Published
6FI0	Crystal structure of BAZ2A PHD zinc finger in complex with Fr 19 分子名称: 2-azanyl-1-(6,7-dihydro-4~{H}-thieno[3,2-c]pyridin-5-yl)ethanone, Bromodomain adjacent to zinc finger domain protein 2A, GLYCEROL, ... 著者 Amato, A, Lucas, X, Bortoluzzi, A, Wright, D, Ciulli, A. 登録日 2018-01-16 公開日 2018-03-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach. ACS Chem. Biol., 13, 2018
6FFA	FMDV Leader protease bound to substrate ISG15 分子名称: GLYCEROL, Lbpro, SULFATE ION, ... 著者 Swatek, K.N, Pruneda, J.N, Komander, D. 登録日 2018-01-05 公開日 2018-02-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BML	Structure of human DHHC20 palmitoyltransferase, irreversibly inhibited by 2-bromopalmitate 分子名称: 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, PALMITIC ACID, PHOSPHATE ION, ... 著者 Rana, M.S, Lee, C.-J, Banerjee, A. 登録日 2017-11-15 公開日 2018-01-24 最終更新日 2018-03-28 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Fatty acyl recognition and transfer by an integral membraneS-acyltransferase. Science, 359, 2018
6BGI	Cryo-EM structure of the TMEM16A calcium-activated chloride channel in nanodisc 分子名称: Anoctamin-1, CALCIUM ION 著者 Dang, S, Feng, S, Tien, J, Peters, C.J, Bulkley, D, Lolicato, M, Zhao, J, Zuberbuhler, K, Ye, W, Qi, J, Chen, T, Craik, C.S, Jan, Y.N, Minor Jr, D.L, Cheng, Y, Jan, L.Y. 登録日 2017-10-28 公開日 2017-12-27 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structures of the TMEM16A calcium-activated chloride channel. Nature, 552, 2017
5CUA	Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with 1-Acetyl-4-(4-hydroxyphenyl)piperazine (SGC - Diamond I04-1 fragment screening) 分子名称: 1,2-ETHANEDIOL, 1-[4-(4-hydroxyphenyl)piperazin-1-yl]ethanone, Bromodomain adjacent to zinc finger domain protein 2B 著者 Bradley, A, Pearce, N, Krojer, T, Ng, J, Talon, R, Vollmar, M, Jose, B, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2015-07-24 公開日 2015-09-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 1-Acetyl-4-(4-hydroxyphenyl)piperazine (SGC - Diamond I04-1 fragment screening) To be published

<402403404405406407408409410411412413414415416417>