PDB: 71589 件ウェブページステータス検索Chemie searchBIRD

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5Q1F	Ligand binding to FARNESOID-X-RECEPTOR 分子名称: Bile acid receptor, COACTIVATOR PEPTIDE SRC-1 HD3, trans-4-({(2S)-2-cyclohexyl-2-[2-(2,6-dimethoxypyridin-3-yl)-5-fluoro-1H-benzimidazol-1-yl]acetyl}amino)cyclohexane-1-carboxylic acid 著者 Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Ruf, A, Joseph, C, Kuhn, B, Shao, C, Yang, H, Burley, S.K. 登録日 2017-05-31 公開日 2017-07-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies. J. Comput. Aided Mol. Des., 32, 2018
5VNF	Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal VV sorting motif 分子名称: C-terminal VV Sorting motif: VAL-THR-SER-VAL-VAL, Protein transport protein Sec23A, Protein transport protein Sec24A, ... 著者 Ma, W, Goldberg, J. 登録日 2017-04-30 公開日 2017-07-05 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.407 Å) 主引用文献 ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
4OJL	Crystal Structure of Putative Tailspike Protein (TSP1, orf210) from Escherichia coli O157:H7 Bacteriohage CBA120 in Complex with Glucose 分子名称: Tailspike protein, ZINC ION, beta-D-glucopyranose 著者 Chen, C, Herzberg, O. 登録日 2014-01-21 公開日 2014-03-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of ORF210 from E. coli O157:H1 phage CBA120 (TSP1), a putative tailspike protein. Plos One, 9, 2014
5Q0S	Ligand binding to FARNESOID-X-RECEPTOR 分子名称: (2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-N-(2-cyanophenyl)-2-cyclohexylacetamide, Bile acid receptor, COACTIVATOR PEPTIDE SRC-1 HD3 著者 Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Ruf, A, Joseph, C, Kuhn, B, Shao, C, Yang, H, Burley, S.K. 登録日 2017-05-31 公開日 2017-07-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies. J. Comput. Aided Mol. Des., 32, 2018
5Q1H	Ligand binding to FARNESOID-X-RECEPTOR 分子名称: (2S)-N,2-dicyclohexyl-2-{2-[4-(1H-tetrazol-5-yl)phenyl]-1H-benzimidazol-1-yl}acetamide, Bile acid receptor, COACTIVATOR PEPTIDE SRC-1 HD3 著者 Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Ruf, A, Joseph, C, Kuhn, B, Shao, C, Yang, H, Burley, S.K. 登録日 2017-05-31 公開日 2017-07-05 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies. J. Comput. Aided Mol. Des., 32, 2018
5VNL	Crystal structure of Sec23a/Sec24a/Sec22 complexed with 4-phenylbutyric acid (1mM soaking) 分子名称: 4-PHENYL-BUTANOIC ACID, Protein transport protein Sec23A, Protein transport protein Sec24A, ... 著者 Ma, W, Goldberg, J. 登録日 2017-04-30 公開日 2017-07-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.394 Å) 主引用文献 ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
4P59	HER3 extracellular domain in complex with Fab fragment of MOR09825 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MOR09825 Fab fragment heavy chain, ... 著者 Sprague, E.R. 登録日 2014-03-15 公開日 2014-04-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 An antibody that locks HER3 in the inactive conformation inhibits tumor growth driven by HER2 or neuregulin. Cancer Res., 73, 2013
4NJ9	Crystal structure of Fab 8B10 in complex with MPTS 分子名称: 8-methoxypyrene-1,3,6-trisulfonic acid, 8B10 heavy chain, 8B10 light chain, ... 著者 Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A. 登録日 2013-11-08 公開日 2014-11-12 最終更新日 2017-06-14 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation. Biochemistry, 54, 2015
4NFI	Crystal structure of human FPPS in complex with magnesium and JDS05120 分子名称: Farnesyl pyrophosphate synthase, MAGNESIUM ION, [({5-[4-(cyclopropyloxy)phenyl]pyridin-3-yl}amino)methanediyl]bis(phosphonic acid) 著者 Park, J, De Schutter, J.W, Tsantrizos, Y.S, Berghuis, A.M. 登録日 2013-10-31 公開日 2014-12-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase. PLoS ONE, 12, 2017
4NCT	Human DYRK1A in complex with PKC412 分子名称: Dual specificity tyrosine-phosphorylation-regulated kinase 1A, PKC412 著者 Alexeeva, M.O, Rothweiler, U. 登録日 2013-10-25 公開日 2015-04-01 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.597 Å) 主引用文献 The structure of a dual-specificity tyrosine phosphorylation-regulated kinase 1A-PKC412 complex reveals disulfide-bridge formation with the anomalous catalytic loop HRD(HCD) cysteine. Acta Crystallogr.,Sect.D, 71, 2015
4NUZ	Crystal structure of a glycosynthase mutant (D233Q) of EndoS, an endo-beta-N-acetyl-glucosaminidase from Streptococcus pyogenes 分子名称: CALCIUM ION, Endo-beta-N-acetylglucosaminidase F2 著者 Trastoy, B, Guenther, S, Snyder, G.A, Sundberg, E.J. 登録日 2013-12-04 公開日 2014-04-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.905 Å) 主引用文献 Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies. Proc.Natl.Acad.Sci.USA, 111, 2014
4P57	MHC TCR peptide complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... 著者 Clayton, G.M, Crawford, F, Kappler, J.W. 登録日 2014-03-14 公開日 2014-07-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158, 2014
4P37	Crystal structure of the Megavirus polyadenylate synthase 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... 著者 Priet, S, Lartigue, A, Claverie, J.M, Abergel, C. 登録日 2014-03-06 公開日 2015-04-01 最終更新日 2015-04-29 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 mRNA maturation in giant viruses: variation on a theme. Nucleic Acids Res., 43, 2015
4LR2	Crystal Structure of Human ENPP4 (apo) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bis(5'-adenosyl)-triphosphatase ENPP4, ... 著者 Albright, R.A, Braddock, D.T. 登録日 2013-07-19 公開日 2013-12-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke. J.Biol.Chem., 289, 2014
4M3X	RB69 DNA polymerase ternary complex with dT/dG at position n-5 of primer/template duplex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Konigsberg, W.H. 登録日 2013-08-06 公開日 2014-02-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant. Protein Sci., 23, 2014
4M18	Crystal Structure of Surfactant Protein-D D325A/R343V mutant in complex with trimannose (Man-a1,2Man-a1,2Man) 分子名称: CALCIUM ION, Pulmonary surfactant-associated protein D, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, ... 著者 Goh, B.C, Rynkiewicz, M.J, Cafarella, T.R, White, M.R, Hartshorn, K.L, Allen, K, Crouch, E.C, Calin, O, Seeberger, P.H, Schulten, K, Seaton, B.A. 登録日 2013-08-02 公開日 2013-12-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.203 Å) 主引用文献 Molecular mechanisms of inhibition of influenza by surfactant protein d revealed by large-scale molecular dynamics simulation. Biochemistry, 52, 2013
4M42	RB69 DNA polymerase ternary complex with dG/dT at position n-4 of primer/tempLate duplex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Konigsberg, W.H. 登録日 2013-08-06 公開日 2014-02-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant. Protein Sci., 23, 2014
4PF0	Structure of the E502A variant of sacteLam55A from Streptomyces sp. SirexAA-E in complex with laminarihexaose 分子名称: 1,2-ETHANEDIOL, Putative secreted protein, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose, ... 著者 Bianchetti, C.M, Takasuka, T.E, Yik, E.J, Bergeman, L.F, Fox, B.G. 登録日 2014-04-25 公開日 2015-03-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Active site and laminarin binding in glycoside hydrolase family 55. J.Biol.Chem., 290, 2015
3T06	Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex with Human RhoA 分子名称: Rho guanine nucleotide exchange factor 11, Transforming protein RhoA 著者 Bielnicki, J.A, Derewenda, U, Derewenda, Z.S. 登録日 2011-07-19 公開日 2011-08-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Insights into the Molecular Activation Mechanism of the RhoA-specific Guanine Nucleotide Exchange Factor, PDZRhoGEF. J.Biol.Chem., 286, 2011
5TXD	Structure of amyloid-beta derived peptide - NKGAIF 分子名称: Amyloid beta A4 protein, PHOSPHATE ION 著者 Sangwan, S, Sawaya, M.R, Eisenberg, D. 登録日 2016-11-16 公開日 2017-11-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.452 Å) 主引用文献 Distal amyloid beta-protein fragments template amyloid assembly. Protein Sci., 27, 2018
5TXH	Polymorphic form 2 of amyloid-beta derived peptide - IFAEDV 分子名称: IFAEDV, ISOPROPYL ALCOHOL 著者 Sangwan, S, Sawaya, M.R, Eisenberg, D. 登録日 2016-11-16 公開日 2017-11-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Distal amyloid beta-protein fragments template amyloid assembly. Protein Sci., 27, 2018
5NYW	Anbu (ancestral beta-subunit) from Yersinia bercovieri 分子名称: 1,2-ETHANEDIOL, AZIDE ION, CHLORIDE ION, ... 著者 Piasecka, A, Czapinska, H, Vielberg, M, Szczepanowski, R.H, Reed, S, Groll, M, Bochtler, M. 登録日 2017-05-12 公開日 2017-05-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 The Y. bercovieri Anbu crystal structure sheds light on the evolution of highly (pseudo)symmetric multimers. J. Mol. Biol., 430, 2018
5SZ0	Carbonic anhydrase II in complex with 4-(phenyl)-benzenesulfonamide 分子名称: 4-(phenyl)-benzenesulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Bhatt, A, Mahon, B.P, Cornelio, B, McKenna, R. 登録日 2016-08-12 公開日 2016-12-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Structure-Activity Relationships of Benzenesulfonamide-Based Inhibitors towards Carbonic Anhydrase Isoform Specificity. Chembiochem, 18, 2017
5TCP	Near-atomic resolution cryo-EM structure of the periplasmic domains of PrgH and PrgK 分子名称: Lipoprotein PrgK, Protein PrgH 著者 Worrall, L.J, Hong, C, Vuckovic, M, Bergeron, J.R.C, Huang, R.K, Yu, Z, Strynadka, N.C.J. 登録日 2016-09-15 公開日 2016-12-21 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body. Nature, 540, 2016
5V91	Crystal structure of fosfomycin resistance protein from Klebsiella pneumoniae 分子名称: Fosfomycin resistance protein, ZINC ION 著者 Klontz, E, Guenther, S, Silverstein, Z, Sundberg, E. 登録日 2017-03-22 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure and Dynamics of FosA-Mediated Fosfomycin Resistance in Klebsiella pneumoniae and Escherichia coli. Antimicrob. Agents Chemother., 61, 2017

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