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7XGK
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Human renin in complex with compound1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, UNKNOWN LIGAND
著者Kashima, A.
登録日2022-04-05
公開日2022-08-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of Novel 2-Carbamoyl Morpholine Derivatives as Highly Potent and Orally Active Direct Renin Inhibitors.
Acs Med.Chem.Lett., 13, 2022
7XNF
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Structure of SARS-CoV-2 antibody P2C-1F11 with GX/P2V/2017 RBD
分子名称: P2C-1F11 Heavy Chain, P2C-1F11 Lambda chain, Spike protein S1
著者Jia, Y.F, Chai, Y, Wang, Q.H, Gao, G.F.
登録日2022-04-28
公開日2023-01-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Cross-reaction of current available SARS-CoV-2 MAbs against the pangolin-origin coronavirus GX/P2V/2017.
Cell Rep, 41, 2022
2VF3
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Aquifex aeolicus IspE in complex with ligand
分子名称: 4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL KINASE, BROMIDE ION, CHLORIDE ION, ...
著者Alphey, M.S, Hunter, W.N.
登録日2007-10-30
公開日2008-11-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Inhibitors of the Kinase Ispe: Structure-Activity Relationships and Co-Crystal Structure Analysis.
Org.Biomol.Chem., 6, 2008
2WHJ
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Understanding how diverse mannanases recognise heterogeneous substrates
分子名称: ACETATE ION, BETA-MANNANASE, GLYCEROL, ...
著者Tailford, L.E, Ducros, V.M.A, Flint, J.E, Roberts, S.M, Morland, C, Zechel, D.L, Smith, N, Bjornvad, M.E, Borchert, T.V, Wilson, K.S, Davies, G.J, Gilbert, H.J.
登録日2009-05-05
公開日2009-05-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Understanding How Diverse -Mannanases Recognise Heterogeneous Substrates.
Biochemistry, 48, 2009
2WJH
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Structure and function of the FeoB G-domain from Methanococcus jannaschii
分子名称: CITRATE ANION, FERROUS IRON TRANSPORT PROTEIN B HOMOLOG, GUANOSINE-5'-DIPHOSPHATE, ...
著者Koester, S, Wehner, M, Herrmann, C, Kuehlbrandt, W, Yildiz, O.
登録日2009-05-26
公開日2009-07-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and Function of the Feob G-Domain from Methanococcus Jannaschii
J.Mol.Biol., 392, 2009
2WJA
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Crystal structure of the tyrosine phosphatase Wzb from Escherichia coli K30 in complex with phosphate.
分子名称: NICKEL (II) ION, PHOSPHATE ION, PUTATIVE ACID PHOSPHATASE WZB
著者Huang, H, Hagelueken, G, Whitfield, C, Naismith, J.H.
登録日2009-05-25
公開日2009-07-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structures of Wzb of Escherichia Coli and Cpsb of Streptococcus Pneumoniae, Representatives of Two Families of Tyrosine Phosphatases that Regulate Capsule Assembly.
J.Mol.Biol., 392, 2009
3F8V
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Evaulaution at Atomic Resolution of the Role of Strain in Destabilizing the Temperature Sensitive T4 Lysozyme Mutant Arg96-->His
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Lysozyme, ...
著者Mooers, B.H.M, Matthews, B.W.
登録日2008-11-13
公開日2009-02-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Evaluation at atomic resolution of the role of strain in destabilizing the temperature-sensitive T4 lysozyme mutant Arg 96 --> His.
Protein Sci., 18, 2009
3FA0
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Evaulaution at Atomic Resolution of the Role of Strain in Destabilizing the Temperature Sensitive T4 Lysozyme Mutant Arg96-->His
分子名称: 2-HYDROXYETHYL DISULFIDE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
著者Mooers, B.H.M, Matthews, B.W.
登録日2008-11-14
公開日2009-02-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.09 Å)
主引用文献Evaluation at atomic resolution of the role of strain in destabilizing the temperature-sensitive T4 lysozyme mutant Arg 96 --> His.
Protein Sci., 18, 2009
2VID
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Serine protease SplB from Staphylococcus aureus at 1.8A resolution
分子名称: SERINE PROTEASE SPLB
著者Dubin, G, Stec-Niemczyk, J, Kisielewska, M, Pustelny, K, Popowicz, G.M, Bista, M, Kantyka, T, Boulware, K.T, Stennicke, H.R, Czarna, A, Phopaisarn, M, Daugherty, P.S, Thogersen, I.B, Enghild, J.J, Thornberry, N, Dubin, A, Potempa, J.
登録日2007-11-30
公開日2008-05-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Enzymatic Activity of the Staphylococcus Aureus Splb Serine Protease is Induced by Substrates Containing the Sequence Trp-Glu-Leu-Gln.
J.Mol.Biol., 379, 2008
2WO6
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Human Dual-Specificity Tyrosine-Phosphorylation-Regulated Kinase 1A in complex with a consensus substrate peptide
分子名称: ARTIFICIAL CONSENSUS SEQUENCE, CHLORIDE ION, DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION- REGULATED KINASE 1A, ...
著者Roos, A.K, Soundararajan, M, Elkins, J.M, Fedorov, O, Eswaran, J, Phillips, C, Pike, A.C.W, Ugochukwu, E, Muniz, J.R.C, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Wikstrom, M, Edwards, A, Bountra, C, Knapp, S.
登録日2009-07-22
公開日2009-08-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of Down Syndrome Kinases, Dyrks, Reveal Mechanisms of Kinase Activation and Substrate Recognition.
Structure, 21, 2013
2VR7
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BU of 2vr7 by Molmil
Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.58 A resolution
分子名称: COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Antonyuk, S, Cao, X, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Selverstone Valentine, J, Hasnain, S.S, Hart, P.J.
登録日2008-03-28
公開日2008-04-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structures of the G85R Variant of Sod1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
7Y8B
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Crystal structure of CotA laccase complexed with syringic acid
分子名称: 3,5-dimethoxy-4-oxidanyl-benzoic acid, COPPER (II) ION, Spore coat protein A, ...
著者Liu, Z.C, Xie, T, Wang, G.G.
登録日2022-06-23
公開日2023-06-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular insights into substrate promiscuity of CotA laccase catalyzing lignin-phenol derivatives.
Int.J.Biol.Macromol., 256, 2023
7Y8C
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Crystal structure of CotA laccase complexed with syringaldehyde
分子名称: 3,5-dimethoxy-4-oxidanyl-benzaldehyde, COPPER (II) ION, Spore coat protein A, ...
著者Liu, Z.C, Xie, T, Wang, G.G.
登録日2022-06-23
公開日2023-06-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular insights into substrate promiscuity of CotA laccase catalyzing lignin-phenol derivatives.
Int.J.Biol.Macromol., 256, 2023
2W8J
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SPT with PLP-ser
分子名称: SERINE PALMITOYLTRANSFERASE, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE
著者Carter, L.G, Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H.
登録日2009-01-16
公開日2009-01-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
2W8T
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SPT with PLP, N100C
分子名称: PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE
著者Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H.
登録日2009-01-19
公開日2009-01-27
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
2WBF
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BU of 2wbf by Molmil
Crystal Structure Analysis of SERA5E from plasmodium falciparum with loop 690-700 ordered
分子名称: CALCIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Smith, B.J, Malby, R.L, Colman, P.M, Clarke, O.B.
登録日2009-02-27
公開日2009-03-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into the protease-like antigen Plasmodium falciparum SERA5 and its noncanonical active-site serine.
J. Mol. Biol., 392, 2009
7Y8A
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Cryo-EM structure of cryptophyte photosystem I
分子名称: (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-3,5,7,9,11,13,15-heptaen-1,17-diynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, ...
著者Zhao, L.S, Zhang, Y.Z, Liu, L.N, Li, K.
登録日2022-06-23
公開日2023-04-12
最終更新日2023-07-12
実験手法ELECTRON MICROSCOPY (2.71 Å)
主引用文献Structural basis and evolution of the photosystem I-light-harvesting supercomplex of cryptophyte algae.
Plant Cell, 35, 2023
2WQO
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STRUCTURE OF NEK2 BOUND TO THE AMINOPYRIDINE CCT241950
分子名称: 4-[2-AMINO-5-(3,4,5-TRIMETHOXYPHENYL)PYRIDIN-3-YL]BENZOIC ACID, CHLORIDE ION, SERINE/THREONINE-PROTEIN KINASE NEK2
著者Mas-Droux, C, Bayliss, R.
登録日2009-08-24
公開日2009-12-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.167 Å)
主引用文献An Autoinhibitory Tyrosine Motif in the Cell-Cycle- Regulated Nek7 Kinase is Released Through Binding of Nek9.
Mol.Cell, 36, 2009
7XRZ
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Crystal structure of BRIL and SRP2070_Fab complex
分子名称: IGG HEAVY CHAIN, IGG LIGHT CHAIN, Soluble cytochrome b562
著者Suzuki, M, Miyagi, H, Yasunaga, M, Asada, H, Iwata, S, Saito, J.
登録日2022-05-12
公開日2023-05-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insight into an anti-BRIL Fab as a G-protein-coupled receptor crystallization chaperone.
Acta Crystallogr D Struct Biol, 79, 2023
2W2V
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Rac2 (G12V) in complex with GTPgS
分子名称: GUANOSINE-5'-TRIPHOSPHATE, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2
著者Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H.
登録日2008-11-04
公開日2009-05-05
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
2W2T
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Rac2 (G12V) in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2
著者Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H.
登録日2008-11-04
公開日2009-05-05
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
2W1A
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Non-covalent complex between dahp synthase and chorismate mutase from Mycobacterium tuberculosis with bound tsa
分子名称: 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE AROG, 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID, CHORISMATE MUTASE, ...
著者Okvist, M, Sasso, S, Roderer, K, Gamper, M, Codoni, G, Krengel, U, Kast, P.
登録日2008-10-16
公開日2009-07-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure and Function of a Complex between Chorismate Mutase and Dahp Synthase: Efficiency Boost for the Junior Partner.
Embo J., 28, 2009
3DK9
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Catalytic cycle of human glutathione reductase near 1 A resolution
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Glutathione reductase, SULFATE ION
著者Berkholz, D.S, Faber, H.R, Savvides, S.N, Karplus, P.A.
登録日2008-06-24
公開日2008-08-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Catalytic cycle of human glutathione reductase near 1 A resolution.
J.Mol.Biol., 382, 2008
7Y9I
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Complex structure of AtYchF1 with ppGpp
分子名称: GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, Obg-like ATPase 1
著者Li, X, Chen, Z.
登録日2022-06-24
公開日2023-07-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Co-crystalization reveals the interaction between AtYchF1 and ppGpp.
Front Mol Biosci, 9, 2022
7Y63
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ApoSIDT2-pH7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 2, ...
著者Gong, D.S.
登録日2022-06-18
公開日2023-06-21
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Structural insight into the human SID1 transmembrane family member 2 reveals its lipid hydrolytic activity.
Nat Commun, 14, 2023

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