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8G34
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Time-resolved cryo-EM study of the 70S recycling by the HflX:1st intermediate
分子名称: 16S, 23S, 30S ribosomal protein S10, ...
著者Bhattacharjee, S, Brown, P.Z, Frank, J.
登録日2023-02-06
公開日2023-12-06
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling.
Cell, 187, 2024
8G38
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BU of 8g38 by Molmil
Time-resolved cryo-EM study of the 70S recycling by the HflX:3rd Intermediate
分子名称: 16S, 23S, 30S ribosomal protein S10, ...
著者Bhattacharjee, S, Brown, P.Z, Frank, J.
登録日2023-02-07
公開日2023-12-06
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling.
Cell, 187, 2024
7UK5
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BU of 7uk5 by Molmil
Human Kv4.2-KChIP2 channel complex in an open state, transmembrane region
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily D member 2
著者Zhao, H, Dai, Y, Lee, C.H.
登録日2022-03-31
公開日2022-06-29
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Activation and closed-state inactivation mechanisms of the human voltage-gated K V 4 channel complexes.
Mol.Cell, 82, 2022
7UNG
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BU of 7ung by Molmil
48-nm repeat of the human respiratory doublet microtubule
分子名称: Cilia- and flagella-associated protein 161, Cilia- and flagella-associated protein 20, Cilia- and flagella-associated protein 45, ...
著者Gui, M, Croft, J.T, Zabeo, D, Acharya, V, Kollman, J.M, Burgoyne, T, Hoog, J.L, Brown, A.
登録日2022-04-11
公開日2022-10-05
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UN1
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BU of 7un1 by Molmil
8-nm repeat of the human sperm tip singlet microtubule
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Gui, M, Croft, J.T, Zabeo, D, Acharya, V, Kollman, J.M, Burgoyne, T, Hoog, J.L, Brown, A.
登録日2022-04-08
公開日2022-10-05
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UQX
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BU of 7uqx by Molmil
Cryo-EM structure of the human Exostosin-1 and Exostosin-2 heterodimer in complex with UDP-GlcNAc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Exostosin-1, Exostosin-2, ...
著者Li, H, Li, H.
登録日2022-04-20
公開日2022-09-28
最終更新日2023-05-17
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for heparan sulfate co-polymerase action by the EXT1-2 complex.
Nat.Chem.Biol., 19, 2023
7UQY
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Cryo-EM structure of the human Exostosin-1 and Exostosin-2 heterodimer in complex with UDP-GlcA
分子名称: Exostosin-1, Exostosin-2, URIDINE-5'-DIPHOSPHATE, ...
著者Li, H, Li, H.
登録日2022-04-20
公開日2022-09-28
最終更新日2023-05-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for heparan sulfate co-polymerase action by the EXT1-2 complex.
Nat.Chem.Biol., 19, 2023
7UWM
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BU of 7uwm by Molmil
Structure of the IL-17A-IL-17RA binary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ...
著者Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C.
登録日2022-05-03
公開日2022-07-27
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Organizing structural principles of the IL-17 ligand-receptor axis.
Nature, 609, 2022
8J07
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96nm repeat of human respiratory doublet microtubule and associated axonemal complexes
分子名称: ACTA2, Axonemal dynein light intermediate polypeptide 1, Calaxin, ...
著者Gui, M, Brown, A.
登録日2023-04-09
公開日2023-07-26
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Axonemal structures reveal mechanoregulatory and disease mechanisms.
Nature, 618, 2023
8J7R
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BU of 8j7r by Molmil
Cryo-EM structure of the J-K-St region of EMCV IRES in complex with eIF4G-HEAT1 and eIF4A (J-K-St/eIF4G focused)
分子名称: Eukaryotic translation initiation factor 4 gamma 1, IRES RNA (J-K-St), MAGNESIUM ION
著者Suzuki, H, Fujiyoshi, Y, Imai, S, Shimada, I.
登録日2023-04-28
公開日2023-08-02
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Dynamically regulated two-site interaction of viral RNA to capture host translation initiation factor.
Nat Commun, 14, 2023
8JIL
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BU of 8jil by Molmil
Cryo-EM structure of niacin bound ketone body receptor HCAR2-Gi signaling complex
分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H.
登録日2023-05-26
公開日2023-09-06
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Mol.Cell, 83, 2023
8IXB
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BU of 8ixb by Molmil
GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin seam region
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ...
著者Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y.
登録日2023-03-31
公開日2023-08-16
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
8IXA
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BU of 8ixa by Molmil
GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin non-seam region
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ...
著者Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y.
登録日2023-03-31
公開日2023-08-16
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
7WI1
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BU of 7wi1 by Molmil
The mutant variant of PNGM-1, H93 was substituuted for alanine to study metal coordination
分子名称: Metallo-beta-lactamase PNGM-1, ZINC ION
著者Park, Y.S, Kang, L.W, Lee, J.H.
登録日2022-01-01
公開日2023-01-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Structural Study of Metal Binding and Coordination in Ancient Metallo-beta-Lactamase PNGM-1 Variants.
Int J Mol Sci, 21, 2020
8JII
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BU of 8jii by Molmil
Cryo-EM structure of compound 9n and niacin bound ketone body receptor HCAR2-Gi signaling complex
分子名称: 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H.
登録日2023-05-26
公開日2023-09-06
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Mol.Cell, 83, 2023
8JHY
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BU of 8jhy by Molmil
Cryo-EM structure of compound 9n bound ketone body receptor HCAR2-Gi signaling complex
分子名称: 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H.
登録日2023-05-25
公開日2023-09-06
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Mol.Cell, 83, 2023
8JIM
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Cryo-EM structure of MMF bound ketone body receptor HCAR2-Gi signaling complex
分子名称: (2Z)-4-methoxy-4-oxobut-2-enoic acid, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H.
登録日2023-05-26
公開日2023-09-06
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Mol.Cell, 83, 2023
7W9N
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BU of 7w9n by Molmil
THE STRUCTURE OF OBA33-OTA COMPLEX
分子名称: (2~{S})-2-[[(3~{R})-5-chloranyl-3-methyl-8-oxidanyl-1-oxidanylidene-3,4-dihydroisochromen-7-yl]carbonylamino]-3-phenyl-propanoic acid, OTA DNA APTAMER (33-MER)
著者Xu, G.H, Li, C.G.
登録日2021-12-10
公開日2022-01-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Insights into the Mechanism of High-Affinity Binding of Ochratoxin A by a DNA Aptamer.
J.Am.Chem.Soc., 144, 2022
7U9X
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Structure of PKA phosphorylated human RyR2-R2474S in the closed state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7UWN
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BU of 7uwn by Molmil
Structure of the IL-17A-IL-17RA-IL-17RC ternary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ...
著者Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C.
登録日2022-05-03
公開日2022-07-27
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Organizing structural principles of the IL-17 ligand-receptor axis.
Nature, 609, 2022
7U9Q
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BU of 7u9q by Molmil
Structure of PKA phosphorylated human RyR2 in the closed state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7UA3
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BU of 7ua3 by Molmil
Structure of PKA phosphorylated human RyR2-R2474S in the closed state in the presence of Calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7U9T
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BU of 7u9t by Molmil
Structure of PKA phosphorylated human RyR2 in the closed state in the presence of Calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7UA1
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Structure of PKA phosphorylated human RyR2-R2474S in the closed state in the presence of ARM210
分子名称: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7UA4
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BU of 7ua4 by Molmil
Structure of PKA phosphorylated human RyR2-R2474S in the open state in the presence of Calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022

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