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6UU9
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BU of 6uu9 by Molmil
E. coli mutant sigma-S transcription initiation complex with an 8-nt RNA ("Fresh" mutant crystal soaked with GTP, UTP, CTP, and ddATP for 30 minutes)
分子名称: 2',3'-DIDEOXYADENOSINE-5'-MONOPHOSPHATE, DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (5.4 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
8EHI
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BU of 8ehi by Molmil
Cryo-EM structure of his-elemental paused elongation complex with an unfolded TL (2)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-14
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (5.5 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
6UU4
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BU of 6uu4 by Molmil
E. coli sigma-S transcription initiation complex with a 3-nt RNA ("old" crystal soaked with GTP and dinucleotide GpA for 30 minutes)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.305 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
8EHF
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BU of 8ehf by Molmil
Cryo-EM structure of his-elemental paused elongation complex with an unfolded TL (1)
分子名称: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-14
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
1AKE
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BU of 1ake by Molmil
STRUCTURE OF THE COMPLEX BETWEEN ADENYLATE KINASE FROM ESCHERICHIA COLI AND THE INHIBITOR AP5A REFINED AT 1.9 ANGSTROMS RESOLUTION: A MODEL FOR A CATALYTIC TRANSITION STATE
分子名称: ADENYLATE KINASE, BIS(ADENOSINE)-5'-PENTAPHOSPHATE
著者Mueller, C.W, Schulz, G.E.
登録日1991-11-08
公開日1994-01-31
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the complex between adenylate kinase from Escherichia coli and the inhibitor Ap5A refined at 1.9 A resolution. A model for a catalytic transition state.
J.Mol.Biol., 224, 1992
8EG8
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BU of 8eg8 by Molmil
Cryo-EM structure of consensus elemental paused elongation complex with a folded TL
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-12
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
2XJK
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BU of 2xjk by Molmil
Monomeric Human Cu,Zn Superoxide dismutase
分子名称: COPPER (II) ION, SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION
著者Saraboji, K, Leinartaite, L, Nordlund, A, Oliveberg, M, Logan, D.T.
登録日2010-07-07
公開日2010-09-01
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Folding Catalysis by Transient Coordination of Zn2+ to the Cu Ligands of the Als-Associated Enzyme Cu/Zn Superoxide Dismutase 1.
J.Am.Chem.Soc., 132, 2010
8EHA
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BU of 8eha by Molmil
Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (out)
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-14
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EGB
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BU of 8egb by Molmil
Cryo-EM structure of consensus elemental paused elongation complex with an unfolded TL
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-12
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EG7
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BU of 8eg7 by Molmil
Cryo-EM structure of pre-consensus elemental paused elongation complex
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-11
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EH8
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BU of 8eh8 by Molmil
Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (1)
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-13
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EH9
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BU of 8eh9 by Molmil
Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (2)
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-13
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
1YPF
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BU of 1ypf by Molmil
Crystal Structure of GuaC (BA5705) from Bacillus anthracis at 1.8 A Resolution
分子名称: GMP reductase
著者Grenha, R, Levdikov, V.M, Blagova, E.V, Fogg, M.J, Brannigan, J.A, Wilkinson, A.J, Wilson, K.S, Structural Proteomics in Europe (SPINE)
登録日2005-01-31
公開日2006-02-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of GuaC (BA5705) from Bacillus anthracis at 1.8 A Resolution.
To be Published
6UTW
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BU of 6utw by Molmil
E. coli sigma-S transcription initiation complex with a 4-nt RNA ("Fresh" crystal)
分子名称: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.854 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UUC
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BU of 6uuc by Molmil
E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching ATP ("Fresh" crystal soaked with ATP for 2 hours)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.096 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UU7
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BU of 6uu7 by Molmil
E. coli sigma-S transcription initiation complex with a 6-nt RNA and an NTP ("Old" crystal soaked with UTP, CTP, ddGTP, and dinucleotide ApG for 30 minutes)
分子名称: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (4.4 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6XA1
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BU of 6xa1 by Molmil
Structure of a drug-like compound stalled human translation termination complex
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.
登録日2020-06-03
公開日2020-10-07
最終更新日2024-12-25
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Selective inhibition of human translation termination by a drug-like compound.
Nat Commun, 11, 2020
8QO1
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BU of 8qo1 by Molmil
Asymmetric structure of the Borrelia bacteriophage BB1 procapsid, 3D class 3
分子名称: Cytosolic protein, DUF228 domain-containing protein, Decoration protein P03, ...
著者Rumnieks, J, Fuzik, T, Tars, K.
登録日2023-10-11
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (9.76 Å)
主引用文献Structure of the Borrelia Bacteriophage phi BB1 Procapsid.
J.Mol.Biol., 435, 2023
3PKJ
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BU of 3pkj by Molmil
Human SIRT6 crystal structure in complex with 2'-N-Acetyl ADP ribose
分子名称: NAD-dependent deacetylase sirtuin-6, SULFATE ION, UNKNOWN ATOM OR ION, ...
著者Pan, P.W, Dong, A, Qiu, W, Loppnau, P, Wang, J, Ravichandran, M, Walker, J.R, Bountra, C, Weigelt, J, Arrowsmith, C.H, Min, J, Edwards, A.M, Structural Genomics Consortium (SGC)
登録日2010-11-11
公開日2011-01-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structure and biochemical functions of SIRT6.
J.Biol.Chem., 286, 2011
8QO0
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BU of 8qo0 by Molmil
Asymmetric structure of the Borrelia bacteriophage BB1 procapsid, 3D class 2
分子名称: Cytosolic protein, DUF228 domain-containing protein, Decoration protein P03, ...
著者Rumnieks, J, Fuzik, T, Tars, K.
登録日2023-09-27
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (10.62 Å)
主引用文献Structure of the Borrelia Bacteriophage phi BB1 Procapsid.
J.Mol.Biol., 435, 2023
6UU5
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BU of 6uu5 by Molmil
E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Old" crystal soaked with GTP, UTP, CTP, and dinucleotide GpA for 30 minutes)
分子名称: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (5.403 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6Y57
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BU of 6y57 by Molmil
Structure of human ribosome in hybrid-PRE state
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A.
登録日2020-02-25
公開日2020-04-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
4DN4
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BU of 4dn4 by Molmil
Crystal structure of the complex between cnto888 fab and mcp-1 mutant p8a
分子名称: ACETATE ION, C-C motif chemokine 2, CNTO888 HEAVY CHAIN, ...
著者Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G.
登録日2012-02-08
公開日2012-10-03
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888.
Mol.Immunol., 51, 2012
6VCN
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BU of 6vcn by Molmil
Crystal structure of E.coli RppH in complex with ppcpG
分子名称: PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, RNA pyrophosphohydrolase, SULFATE ION
著者Gao, A, Vasilyev, N, Kaushik, A, Duan, W, Serganov, A.
登録日2019-12-21
公開日2020-02-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Principles of RNA and nucleotide discrimination by the RNA processing enzyme RppH.
Nucleic Acids Res., 48, 2020
9DCH
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BU of 9dch by Molmil
Single-stranded RNA-mediated PRC2 dimer
分子名称: Isoform 2 of Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, Polycomb protein SUZ12, ...
著者Song, J.S, Kasinath, V.K.
登録日2024-08-26
公開日2025-03-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Diverse RNA Structures Induce PRC2 Dimerization and Inhibit Histone Methyltransferase Activity.
Biorxiv, 2024

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件を2025-07-09に公開中

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