5G0V
| InhA in complex with a DNA encoded library hit | 分子名称: | ENOYL-ACYL CARRIER PROTEIN REDUCTASE, MAGNESIUM ION, N-[2-(methylamino)-2-oxidanylidene-ethyl]-2-(4-pyrazol-1-ylphenyl)-N-(1-pyridin-2-ylpiperidin-4-yl)ethanamide, ... | 著者 | Read, J.A, Breed, J. | 登録日 | 2016-03-22 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Discovery of Cofactor-Specific, Bactericidal Mycobacterium Tuberculosis Inha Inhibitors Using DNA-Encoded Library Technology Proc.Natl.Acad.Sci.USA, 113, 2016
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3FU5
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3FUJ
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3FVR
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7CW3
| Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG (subregion around icosahedral 2-fold vertex) | 分子名称: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | 著者 | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | 登録日 | 2020-08-27 | 公開日 | 2020-11-04 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | 主引用文献 | Structural basis of Chikungunya virus inhibition by monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 117, 2020
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5F89
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3FWX
| The crystal structure of the peptide deformylase from Vibrio cholerae O1 biovar El Tor str. N16961 | 分子名称: | Peptide deformylase, ZINC ION | 著者 | Zhang, R, Zhou, M, Stam, J, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2009-01-19 | 公開日 | 2009-03-17 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The crystal structure of the peptide deformylase from Vibrio cholerae O1 biovar El Tor To be Published
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3FTV
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2P6J
| Full-sequence computational design and solution structure of a thermostable protein variant | 分子名称: | designed engrailed homeodomain variant UVF | 著者 | Shah, P.S, Hom, G.K, Ross, S.A, Lassila, J.K, Crowhurst, K.A, Mayo, S.L. | 登録日 | 2007-03-18 | 公開日 | 2007-08-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Full-sequence Computational Design and Solution Structure of a Thermostable Protein Variant. J.Mol.Biol., 372, 2007
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2P8O
| Crystal Structure of a Benzohydroxamic Acid/Vanadate complex bound to chymotrypsin A | 分子名称: | Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... | 著者 | Moulin, A, Bell, J.H, Pratt, R.F, Ringe, D. | 登録日 | 2007-03-22 | 公開日 | 2007-05-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Inhibition of chymotrypsin by a complex of ortho-vanadate and benzohydroxamic Acid: structure of the inert complex and its mechanistic interpretation. Biochemistry, 46, 2007
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5FA5
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3GEH
| Crystal structure of MnmE from Nostoc in complex with GDP, FOLINIC ACID and ZN | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, ZINC ION, ... | 著者 | Meyer, S, Wittinghofer, A. | 登録日 | 2009-02-25 | 公開日 | 2009-10-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Kissing G domains of MnmE monitored by X-ray crystallography and pulse electron paramagnetic resonance spectroscopy Plos Biol., 7, 2009
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3GFR
| Structure of YhdA, D137L variant | 分子名称: | FLAVIN MONONUCLEOTIDE, FMN-dependent NADPH-azoreductase | 著者 | Staunig, N, Gruber, K. | 登録日 | 2009-02-27 | 公開日 | 2009-09-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.403 Å) | 主引用文献 | A single intersubunit salt bridge affects oligomerization and catalytic activity in a bacterial quinone reductase Febs J., 276, 2009
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4DGG
| c-SRC kinase domain in complex with RM-1-176 | 分子名称: | 3-{6-[(3-chlorobenzyl)oxy]naphthalen-2-yl}-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src | 著者 | Merritt, E.A, Larson, E.T. | 登録日 | 2012-01-25 | 公開日 | 2012-10-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Active site profiling reveals coupling between domains in SRC-family kinases. Nat.Chem.Biol., 9, 2013
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5WNO
| Crystal structure of C. elegans LET-23 kinase domain complexed with AMP-PNP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Receptor tyrosine-protein kinase let-23 | 著者 | Liu, L, Thaker, T.M, Jura, N. | 登録日 | 2017-08-01 | 公開日 | 2018-01-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.386 Å) | 主引用文献 | Regulation of Kinase Activity in the Caenorhabditis elegans EGF Receptor, LET-23. Structure, 26, 2018
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4WII
| HUMAN SPLICING FACTOR, CONSTRUCT 3 | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Splicing factor, ... | 著者 | lee, M, bond, c.s. | 登録日 | 2014-09-26 | 公開日 | 2015-04-01 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation. Nucleic Acids Res., 43, 2015
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4WKU
| n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ | 分子名称: | Acyl-homoserine lactone acylase PvdQ, GLYCEROL, hexyl(trihydroxy)borate(1-) | 著者 | Wu, R, Clevenger, K.D, Fast, W, Liu, D. | 登録日 | 2014-10-03 | 公開日 | 2014-11-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ. Biochemistry, 53, 2014
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3MI3
| Homocitrate Synthase Lys4 bound to Lysine | 分子名称: | Homocitrate synthase, mitochondrial, LYSINE, ... | 著者 | Bulfer, S.L, Scott, E.M, Pillus, L, Trievel, R.C. | 登録日 | 2010-04-09 | 公開日 | 2010-04-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Structural Basis for L-lysine Feedback Inhibition of Homocitrate Synthase J.Biol.Chem., 285, 2010
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4DOV
| Structure of free mouse ORC1 BAH domain | 分子名称: | Origin recognition complex subunit 1 | 著者 | Song, J, Patel, D.J. | 登録日 | 2012-02-10 | 公開日 | 2012-03-07 | 最終更新日 | 2012-04-11 | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | 主引用文献 | The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome. Nature, 484, 2012
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3GEE
| Crystal structure of MnmE from Chlorobium tepidum in complex with GDP and FOLINIC ACID | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, tRNA modification GTPase mnmE | 著者 | Meyer, S, Wittinghofer, A. | 登録日 | 2009-02-25 | 公開日 | 2009-10-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Kissing G domains of MnmE monitored by X-ray crystallography and pulse electron paramagnetic resonance spectroscopy Plos Biol., 7, 2009
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5GHX
| Crystal structure of beta-lactamase PenP mutant-E166H | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, Beta-lactamase | 著者 | Pan, X, Zhao, Y. | 登録日 | 2016-06-21 | 公開日 | 2017-01-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Crystallographic Snapshots of Class A beta-Lactamase Catalysis Reveal Structural Changes That Facilitate beta-Lactam Hydrolysis J. Biol. Chem., 292, 2017
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4DRR
| Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen | 分子名称: | Outer capsid protein VP4, SODIUM ION | 著者 | Hu, L, Crawford, S.E, Czako, R, Cortes-Penfield, N.W, Smith, D.F, Le Pendu, J, Estes, M.K, Prasad, B.V.V. | 登録日 | 2012-02-17 | 公開日 | 2012-04-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen. Nature, 485, 2012
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3MKS
| Crystal Structure of yeast Cdc4/Skp1 in complex with an allosteric inhibitor SCF-I2 | 分子名称: | 1,1'-binaphthalene-2,2'-dicarboxylic acid, Cell division control protein 4, GLYCEROL, ... | 著者 | Orlicky, S, Sicheri, F, Tyers, M, Tang, X. | 登録日 | 2010-04-15 | 公開日 | 2010-07-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | An allosteric inhibitor of substrate recognition by the SCF(Cdc4) ubiquitin ligase. Nat.Biotechnol., 28, 2010
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2O9B
| Crystal Structure of Bacteriophytochrome chromophore binding domain | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome | 著者 | Wagner, J.R, Brunzelle, J.S, Vierstra, R.D, Forest, K.T. | 登録日 | 2006-12-13 | 公開日 | 2007-03-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | High resolution structure of deinococcus bacteriophytochrome yields new insights into phytochrome architecture and evolution. J.Biol.Chem., 282, 2007
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2OEM
| Crystal structure of a rubisco-like protein from Geobacillus kaustophilus liganded with Mg2+ and 2,3-diketohexane 1-phosphate | 分子名称: | (1Z)-2-HYDROXY-3-OXOHEX-1-EN-1-YL DIHYDROGEN PHOSPHATE, 2,3-diketo-5-methylthiopentyl-1-phosphate enolase, MAGNESIUM ION | 著者 | Fedorov, A.A, Imker, H.J, Fedorov, E.V, Gerlt, J.A, Almo, S.C. | 登録日 | 2006-12-30 | 公開日 | 2007-03-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mechanistic Diversity in the RuBisCO Superfamily: The "Enolase" in the Methionine Salvage Pathway in Geobacillus kaustophilus. Biochemistry, 46, 2007
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