PDB: 19255 件ウェブページステータス検索Chemie searchBIRD

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2PBN	Crystal structure of the human tyrosine receptor phosphate gamma 分子名称: Receptor-type tyrosine-protein phosphatase gamma, SULFATE ION 著者 Bonanno, J.B, Freeman, J, Bain, K.T, Reyes, C, Pelletier, L, Jin, X, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2007-03-28 公開日 2007-04-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural genomics of protein phosphatases. J.Struct.Funct.Genom., 8, 2007
6GOZ	Structure of mEos4b in the green long-lived dark state 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 De Zitter, E, Adam, V, Byrdin, M, Van Meervelt, L, Dedecker, P, Bourgeois, D. 登録日 2018-06-04 公開日 2019-11-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.406 Å) 主引用文献 Mechanistic Investigations of Green mEos4b Reveal a Dynamic Long-Lived Dark State. J.Am.Chem.Soc., 2020
2P7E	Vanadate at the Active Site of a Small Ribozyme Suggests a Role for Water in Transition-State Stabilization 分子名称: 3' substrate strand, octameric fragment, 5' substrate strand, ... 著者 Torelli, A.T, Krucinska, J, Wedekind, J.E. 登録日 2007-03-20 公開日 2007-05-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization Rna, 13, 2007
2P7U	The crystal structure of rhodesain, the major cysteine protease of T. brucei rhodesiense, bound to inhibitor K777 分子名称: Cysteine protease, NALPHA-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-N-{(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}-L-PHENYLALANINAMIDE 著者 Brinen, L.S, Marion, R. 登録日 2007-03-20 公開日 2008-03-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Vinyl sulfones as antiparasitic agents and a structural basis for drug design. J.Biol.Chem., 284, 2009
6H5T	Intersectin SH3A short isoform 分子名称: 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, ACETATE ION, CHLORIDE ION, ... 著者 Driller, J.H, Gerth, F, Freund, C, Wahl, M.C, Loll, B. 登録日 2018-07-25 公開日 2019-02-27 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.689 Å) 主引用文献 Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain. Structure, 27, 2019
2Q7U	Crystal Structure of the F plasmid TraI Relaxase Domain with the Scissile Thymidine Base and Imidodiphosphate 分子名称: IMIDO DIPHOSPHATE, MAGNESIUM ION, Protein traI, ... 著者 Lujan, S.A, Redinbo, M.R. 登録日 2007-06-07 公開日 2008-05-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase. Proc.Natl.Acad.Sci.Usa, 104, 2007
5OL3	Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp013 and RKp117 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, [2-[(4-isoquinolin-5-ylsulfonyl-1,4-diazepan-1-yl)methyl]phenyl]boronic acid, ... 著者 Mueller, J.M, Heine, A, Klebe, G. 登録日 2017-07-26 公開日 2018-08-29 最終更新日 2019-05-15 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019
2OQI	Human Dipeptidyl Peptidase IV (DPP4) with Piperidinone-constrained phenethylamine 分子名称: (4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE, Dipeptidyl peptidase 4 (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (Adenosine deaminase complexing protein 2) (ADABP) 著者 Pei, Z, Li, X, von Geldern, T.W, Longenecker, K.L, Pireh, D, Stewart, K.D, Backes, B.J, Lai, C, Lubben, T.H, Ballaron, S.J, Beno, D.W, Kempf-Grote, A.J, Sham, H.L, Trevillyan, J.M. 登録日 2007-01-31 公開日 2007-04-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery and Structure-Activity Relationships of Piperidinone- and Piperidine-Constrained Phenethylamines as Novel, Potent, and Selective Dipeptidyl Peptidase IV Inhibitors. J.Med.Chem., 50, 2007
5OTG	Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp013 and RKp190 分子名称: [2-[[2-(isoquinolin-5-ylsulfonylamino)ethylamino]methyl]phenyl]boronic acid, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor 著者 Mueller, J.M, Heine, A, Klebe, G. 登録日 2017-08-21 公開日 2018-09-05 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp013 and RKp190 To be published
4BNE	Pacsin2 Interacts with Membranes and Actin-Filaments 分子名称: PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 2, SULFATE ION, TRIETHYLENE GLYCOL 著者 Kostan, J, Salzer, U, Orlova, A, Toeroe, I, Hodnik, V, Schreiner, C, Merilainen, J, Nikki, M, Virtanen, I, Lehto, V.-P, Anderluh, G, Egelman, E.H, Djinovic-Carugo, K. 登録日 2013-05-15 公開日 2014-05-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Direct Interaction of Actin Filaments with F-Bar Protein Pacsin2. Embo Rep., 15, 2014
2OZ2	Crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (K11777) 分子名称: Cruzipain, NALPHA-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-N-{(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}-L-PHENYLALANINAMIDE, SULFATE ION 著者 Rickert, M, Brinen, L. 登録日 2007-02-23 公開日 2008-02-26 最終更新日 2019-09-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Vinyl sulfones as antiparasitic agents and a structural basis for drug design. J.Biol.Chem., 284, 2009
2OMX	Crystal structure of InlA S192N G194S+S/hEC1 complex 分子名称: CALCIUM ION, CHLORIDE ION, Epithelial-cadherin, ... 著者 Wollert, T, Heinz, D.W, Schubert, W.D. 登録日 2007-01-23 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. Proc.Natl.Acad.Sci.Usa, 104, 2007
2PNN	Crystal Structure of the Ankyrin Repeat Domain of Trpv1 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Transient receptor potential cation channel subfamily V member 1 著者 Jin, X, Gaudet, R. 登録日 2007-04-24 公開日 2007-07-03 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Ankyrin Repeats of TRPV1 Bind Multiple Ligands and Modulate Channel Sensitivity. Neuron, 54, 2007
2P53	Crystal structure of N-acetyl-D-glucosamine-6-phosphate deacetylase D273N mutant complexed with N-acetyl phosphonamidate-d-glucosamine-6-phosphate 分子名称: 2-deoxy-2-{[(S)-hydroxy(methyl)phosphoryl]amino}-6-O-phosphono-alpha-D-glucopyranose, N-acetylglucosamine-6-phosphate deacetylase, ZINC ION 著者 Fedorov, A.A, Fedorov, E.V, Hall, R.S, Raushel, F.M, Almo, S.C. 登録日 2007-03-14 公開日 2007-07-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Diversity within the Mononuclear and Binuclear Active Sites of N-Acetyl-d-glucosamine-6-phosphate Deacetylase. Biochemistry, 46, 2007
2OMZ	Crystal structure of InlA Y369A/hEC1 complex 分子名称: Epithelial-cadherin, Internalin-A 著者 Wollert, T, Heinz, D.W, Schubert, W.D. 登録日 2007-01-23 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. Proc.Natl.Acad.Sci.Usa, 104, 2007
2P8S	Human dipeptidyl peptidase IV/CD26 in complex with a cyclohexalamine inhibitor 分子名称: (1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G, Biftu, T. 登録日 2007-03-23 公開日 2007-05-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin Bioorg.Med.Chem.Lett., 17, 2007
2OMT	Crystal structure of InlA G194S+S/hEC1 complex 分子名称: CALCIUM ION, CHLORIDE ION, Epithelial-cadherin; E-Cad/CTF1, ... 著者 Wollert, T, Heinz, D.W, Schubert, W.D. 登録日 2007-01-23 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. Proc.Natl.Acad.Sci.Usa, 104, 2007
2N8V	An NMR/SAXS structure of the PKI domain of the honeybee dicistrovirus, Israeli acute paralysis virus (IAPV) IRES 分子名称: RNA (70-MER) 著者 Au, H.H, Cornilescu, G, Mouzakis, K.D, Burke, J.E, Ren, Q, Lee, S, Butcher, S.E, Jan, E. 登録日 2015-10-27 公開日 2015-11-11 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Global shape mimicry of tRNA within a viral internal ribosome entry site mediates translational reading frame selection. Proc.Natl.Acad.Sci.USA, 112, 2015
2NMQ	Simultaneous determination of protein structure and dynamics using rdcs 分子名称: Immunoglobulin G-binding protein G precursor 著者 Blackledge, M, Bouvignies, G, Brueschweiler, R, Markwick, P. 登録日 2006-10-23 公開日 2006-11-21 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Simultaneous determination of protein backbone structure and dynamics from residual dipolar couplings J.Am.Chem.Soc., 128, 2006
2NLR	STREPTOMYCES LIVIDANS ENDOGLUCANASE (EC: 3.2.1.4) COMPLEX WITH MODIFIED GLUCOSE TRIMER 分子名称: PROTEIN (ENDOGLUCANASE (E.C.3.2.1.4)), beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-beta-D-glucopyranose 著者 Sulzenbacher, G, Dupont, C, Davies, G.J. 登録日 1998-11-02 公開日 1999-11-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 The crystal structure of a 2-fluorocellotriosyl complex of the Streptomyces lividans endoglucanase CelB2 at 1.2 A resolution. Biochemistry, 38, 1999
2NQP	Crystal structure of pseudoudirinde synthase TruA in complex with leucyl tRNA 分子名称: POTASSIUM ION, tRNA pseudouridine synthase A, transfer RNA 著者 Hur, S, Stroud, R.M. 登録日 2006-10-31 公開日 2007-05-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 How U38, 39, and 40 of Many tRNAs Become the Targets for Pseudouridylation by TruA. Mol.Cell, 26, 2007
2NBT	NEURONAL BUNGAROTOXIN, NMR, 10 STRUCTURES 分子名称: NEURONAL BUNGAROTOXIN 著者 Oswald, R.E, Sutcliffe, M.J, Bamberger, M, Loring, R.H, Braswell, E, Dobson, C.M. 登録日 1997-10-29 公開日 1998-03-11 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of neuronal bungarotoxin determined by two-dimensional NMR spectroscopy: calculation of tertiary structure using systematic homologous model building, dynamical simulated annealing, and restrained molecular dynamics. Biochemistry, 31, 1992
2Q5E	Crystal structure of human carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 分子名称: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2, MAGNESIUM ION 著者 Bonanno, J.B, Dickey, M, Bain, K.T, Lau, C, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2007-05-31 公開日 2007-06-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Structural genomics of protein phosphatases. J.Struct.Funct.Genom., 8, 2007
2Q7T	Crystal Structure of the F plasmid TraI Relaxase Domain with the Scissile Thymidine Base 分子名称: MAGNESIUM ION, Protein traI, THYMIDINE-5'-PHOSPHATE 著者 Lujan, S.A, Redinbo, M.R. 登録日 2007-06-07 公開日 2008-05-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase. Proc.Natl.Acad.Sci.Usa, 104, 2007
2OZO	Autoinhibited intact human ZAP-70 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Tyrosine-protein kinase ZAP-70 著者 Deindl, S, Kadlecek, T.A, Brdicka, T, Cao, X, Weiss, A, Kuriyan, J. 登録日 2007-02-26 公開日 2007-05-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Basis for the Inhibition of Tyrosine Kinase Activity of ZAP-70. Cell(Cambridge,Mass.), 129, 2007

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