PDB: 1292 件ウェブページステータス検索Chemie searchBIRD

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7XNX	High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Cheng, J, Beckmann, R. 登録日 2022-04-30 公開日 2023-04-05 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia. Cancer Discov, 13, 2023
7XNY	High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Cheng, J, Beckmann, R. 登録日 2022-04-30 公開日 2023-04-05 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia. Cancer Discov, 13, 2023
4RB3	Crystal structure of Magnetospirillum gryphiswaldense MSR-1 Fur-Mn2+-feoAB1 operator 分子名称: DNA (25-MER), DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), MANGANESE (II) ION, ... 著者 Deng, Z, Chen, Z. 登録日 2014-09-12 公開日 2015-07-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator. Nat Commun, 6
4RB2	Crystal structure of Magnetospirillum gryphiswaldense MSR-1 SeMet-Fur-Mn2+-feoAB1 operator 分子名称: DNA (25-MER), DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), MANGANESE (II) ION 著者 Deng, Z, Chen, Z. 登録日 2014-09-12 公開日 2015-07-15 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator. Nat Commun, 6
4RB1	Crystal structure of Magnetospirillum gryphiswaldense MSR-1 Fur-Mn2+-E. coli Fur box 分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*TP*AP*AP*TP*GP*AP*TP*AP*AP*TP*CP*AP*TP*TP*AP*TP*CP*CP*GP*C)-3'), DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), MANGANESE (II) ION 著者 Deng, Z, Chen, Z. 登録日 2014-09-12 公開日 2015-07-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator. Nat Commun, 6
2AV7	Crystal structure of HTLV-1 TAX peptide Bound to Human Class I MHC HLA-A2 with the K66A mutation in the heavy chain. 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Borbulevych, O.Y, Baker, B.M. 登録日 2005-08-29 公開日 2005-10-18 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Unraveling a Hotspot for TCR Recognition on HLA-A2: Evidence Against the Existence of Peptide-independent TCR Binding Determinants. J.Mol.Biol., 353, 2005
2AV1	Crystal structure of HTLV-1 TAX peptide Bound to Human Class I MHC HLA-A2 with the E63Q and K66A mutations in the heavy chain. 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Borbulevych, O.Y, Baker, B.M. 登録日 2005-08-29 公開日 2005-10-18 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Unraveling a Hotspot for TCR Recognition on HLA-A2: Evidence Against the Existence of Peptide-independent TCR Binding Determinants. J.Mol.Biol., 353, 2005
4I7H	Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes 分子名称: NICKEL (II) ION, ZINC ION, peroxide stress sensing regulator 著者 Kumaraswami, M. 登録日 2012-11-30 公開日 2013-05-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Peroxide Stress Regulator from Streptococcus pyogenes Provides Functional Insights into the Mechanism of Oxidative Stress Sensing. J.Biol.Chem., 288, 2013
1P92	Crystal Structure of (H79A)DtxR 分子名称: BETA-MERCAPTOETHANOL, Diphtheria toxin repressor 著者 D'Aquino, J.A, Ringe, D. 登録日 2003-05-08 公開日 2004-05-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Determinants of the SRC homology domain 3-like fold. J.Bacteriol., 185, 2003
6NF7	Crystal Structure of RT1.Aa-Bu31-10 分子名称: Beta-2-microglobulin, Bu31-10 peptide, RT1A.a 著者 Gras, S. 登録日 2018-12-19 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Cross-Reactive Donor-Specific CD8+Tregs Efficiently Prevent Transplant Rejection. Cell Rep, 29, 2019
2N0A	Atomic-resolution structure of alpha-synuclein fibrils 分子名称: Alpha-synuclein 著者 Tuttle, M.D, Comellas, G, Nieuwkoop, A.J, Covell, D.J, Berthold, D.A, Kloepper, K.D, Courtney, J.M, Kim, J.K, Schwieters, C.D, Lee, V.M, George, J.M, Rienstra, C.M. 登録日 2015-03-04 公開日 2016-03-23 最終更新日 2024-05-15 実験手法 SOLID-STATE NMR 主引用文献 Solid-state NMR structure of a pathogenic fibril of full-length human alpha-synuclein. Nat.Struct.Mol.Biol., 23, 2016
2J80	Structure of Citrate-bound Periplasmic Domain of Sensor Histidine Kinase CitA 分子名称: CITRATE ANION, GLYCEROL, SENSOR KINASE CITA, ... 著者 Sevvana, M, Vijayan, V, Zweckstetter, M, Reinelt, S, Madden, D.R, Sheldrick, G.M, Bott, M, Griesinger, C, Becker, S. 登録日 2006-10-18 公開日 2007-10-23 最終更新日 2019-05-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A Ligand-Induced Switch in the Periplasmic Domain of Sensor Histidine Kinase Cita. J.Mol.Biol., 377, 2008
3ZDS	Structure of homogentisate 1,2-dioxygenase in complex with reaction intermediates of homogentisate with oxygen. 分子名称: 2-(3,6-DIHYDROXYPHENYL)ACETIC ACID, 2-(6-oxidanyl-3-oxidanylidene-cyclohexa-1,4-dien-1-yl)ethanoic acid, 2-[(6R)-6-(dioxidanyl)-6-oxidanyl-3-oxidanylidene-cyclohexa-1,4-dien-1-yl]ethanoic acid, ... 著者 Jeoung, J.-H, Bommer, M, Lin, T.-Y, Dobbek, H. 登録日 2012-11-30 公開日 2013-07-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Visualizing the Substrate-, Superoxo-, Alkylperoxo- and Product-Bound States at the Non-Heme Fe(II) Site of Homogentisate Dioxygenase Proc.Natl.Acad.Sci.USA, 110, 2013
4AQ2	resting state of homogentisate 1,2-dioxygenase 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE (III) ION, HOMOGENTISATE 1,2-DIOXYGENASE 著者 Jeoung, J.-H, Lin, T.-Y, Bommer, M, Dobbek, H. 登録日 2012-04-12 公開日 2013-04-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Visualizing the Substrate-, Superoxo-, Alkylperoxo-, and Product-Bound States at the Nonheme Fe(II) Site of Homogentisate Dioxygenase. Proc.Natl.Acad.Sci.USA, 110, 2013
5GNJ	Structure of a transcription factor and DNA complex 分子名称: DNA (5'-D(*AP*GP*GP*AP*AP*CP*AP*CP*GP*TP*GP*AP*CP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*GP*TP*CP*AP*CP*GP*TP*GP*TP*TP*CP*C)-3'), Transcription factor MYC2 著者 Lian, T, Xu, Y, Su, X. 登録日 2016-07-21 公開日 2017-05-10 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structure of Tetrameric Arabidopsis MYC2 Reveals the Mechanism of Enhanced Interaction with DNA. Cell Rep, 19, 2017
2J8U	Large CDR3a loop alteration as a function of MHC mutation. 分子名称: AHIII TCR ALPHA CHAIN, AHIII TCR BETA CHAIN, Beta-2-microglobulin, ... 著者 Miller, P.J, Benhar, Y.P, Biddison, W, Collins, E.J. 登録日 2006-10-27 公開日 2007-10-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Single MHC mutation eliminates enthalpy associated with T cell receptor binding. J. Mol. Biol., 373, 2007
4AQ6	substrate bound homogentisate 1,2-dioxygenase 分子名称: 2-(3,6-DIHYDROXYPHENYL)ACETIC ACID, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE (III) ION, ... 著者 Jeoung, J.-H, Lin, T.-Y, Bommer, M, Dobbek, H. 登録日 2012-04-12 公開日 2013-04-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Visualizing the Substrate-, Superoxo-, Alkylperoxo- and Product-Bound States at the Non-Heme Fe(II) Site of Homogentisate Dioxygenase Proc.Natl.Acad.Sci.USA, 110, 2013
4RAY	Crystal structure of Magnetospirillum gryphiswaldense MSR-1 Apo-Fur 分子名称: CITRATE ANION, DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), SULFATE ION 著者 Deng, Z, Liu, Z, Chen, Z. 登録日 2014-09-12 公開日 2015-07-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator. Nat Commun, 6
3GLX	Crystal Structure Analysis of the DtxR(E175K) complexed with Ni(II) 分子名称: Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION 著者 D'Aquino, J.A, Denninger, A, Moulin, A, D'Aquino, K.E, Ringe, D. 登録日 2009-03-12 公開日 2009-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Decreased sensitivity to changes in the concentration of metal ions as the basis for the hyperactivity of DtxR(E175K). J.Mol.Biol., 390, 2009
4RAZ	Crystal structure of Magnetospirillum gryphiswaldense MSR-1 holo-Fur 分子名称: 1,2-ETHANEDIOL, DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), MANGANESE (II) ION 著者 Deng, Z, Wang, Q, Chen, Z. 登録日 2014-09-12 公開日 2015-07-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator. Nat Commun, 6
5XE7	Crystal structure of Mycobacterium tuberculosis extracytoplasmic function sigma factor SigJ 分子名称: ECF RNA polymerase sigma factor SigJ 著者 Goutam, K, Gopal, B. 登録日 2017-04-01 公開日 2017-07-19 最終更新日 2017-10-04 実験手法 X-RAY DIFFRACTION (2.162 Å) 主引用文献 The fused SnoaL_2 domain in the Mycobacterium tuberculosis sigma factor sigma J modulates promoter recognition Nucleic Acids Res., 45, 2017
4RB0	Crystal structure of Magnetospirillum gryphiswaldense MSR-1 SeMet-Apo-Fur 分子名称: CITRATE ANION, DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), SULFATE ION 著者 Deng, Z, Chen, Z. 登録日 2014-09-12 公開日 2015-07-15 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator. Nat Commun, 6
6A1G	Crystal structure of human DYRK1A in complex with compound 32 分子名称: 5,5-dimethyl-8-[1-(piperidin-4-yl)ethenyl]-5,6-dihydrobenzo[h]quinazolin-4-amine, Dual specificity tyrosine-phosphorylation-regulated kinase 1A 著者 Baba, D, Hanzawa, H. 登録日 2018-06-07 公開日 2018-10-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Discovery of DS42450411 as a potent orally active hepcidin production inhibitor: Design and optimization of novel 4-aminopyrimidine derivatives. Bioorg. Med. Chem. Lett., 28, 2018
5WJ5	Human TRPML1 channel structure in closed conformation 分子名称: Mucolipin-1 著者 Schmiege, P, Li, X. 登録日 2017-07-21 公開日 2017-10-18 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Human TRPML1 channel structures in open and closed conformations. Nature, 550, 2017
6A1F	Crystal structure of human DYRK1A in complex with compound 14 分子名称: 8-methoxy-5,5-dimethyl-5,6-dihydrobenzo[h]quinazolin-4-amine, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, SULFATE ION, ... 著者 Baba, D, Hanzawa, H. 登録日 2018-06-07 公開日 2018-10-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Discovery of DS42450411 as a potent orally active hepcidin production inhibitor: Design and optimization of novel 4-aminopyrimidine derivatives. Bioorg. Med. Chem. Lett., 28, 2018

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