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3CJ0
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments
分子名称: 4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
2LNM
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Solution structure of the C-terminal NP-repeat domain of Tic40, a co-chaperone during protein import into chloroplasts
分子名称: Protein TIC 40, chloroplastic
著者Chen, C, Kao, Y.
登録日2012-01-01
公開日2012-11-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the C-terminal NP-repeat domain of Tic40, a co-chaperone during protein import into chloroplasts.
J.Biochem., 152, 2012
335D
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THE CRYSTAL STRUCTURE OF THE DNA DECAMER D(GGCAATTGCG) CONTAINS BOTH MAJOR AND MINOR GROOVE BINDING G.(G.C) TRIPLETS
分子名称: DNA (5'-D(*GP*GP*CP*AP*AP*TP*TP*GP*CP*G)-3'), MAGNESIUM ION
著者Nunn, C.M, Neidle, S.
登録日1997-06-05
公開日1998-08-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the DNA decamer d(GGCAATTGCG) contains both major- and minor-groove binding G.(G.C) base triplets.
Acta Crystallogr.,Sect.D, 54, 1998
3CJ3
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ2
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3V46
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Crystal Structure of Yeast Cdc73 C-Terminal Domain
分子名称: Cell division control protein 73
著者Amrich, C.G, VanDemark, A.P.
登録日2011-12-14
公開日2012-02-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.549 Å)
主引用文献Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin.
J.Biol.Chem., 287, 2012
2REU
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Crystal Structure of the C-terminal of Sau3AI fragment
分子名称: MAGNESIUM ION, Type II restriction enzyme Sau3AI
著者Hu, X, Yu, F, Xu, C, He, J.
登録日2007-09-27
公開日2008-09-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure and function of C-terminal Sau3AI domain
Biochim.Biophys.Acta, 1794, 2009
100D
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CRYSTAL STRUCTURE OF THE HIGHLY DISTORTED CHIMERIC DECAMER R(C)D(CGGCGCCG)R(G)-SPERMINE COMPLEX-SPERMINE BINDING TO PHOSPHATE ONLY AND MINOR GROOVE TERTIARY BASE-PAIRING
分子名称: DNA/RNA (5'-R(*CP*)-D(*CP*GP*GP*CP*GP*CP*CP*GP*)-R(*G)-3'), SPERMINE
著者Ban, C, Ramakrishnan, B, Sundaralingam, M.
登録日1994-12-05
公開日1995-03-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the highly distorted chimeric decamer r(C)d(CGGCGCCG)r(G).spermine complex--spermine binding to phosphate only and minor groove tertiary base-pairing.
Nucleic Acids Res., 22, 1994
2YLM
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Mechanism of USP7 (HAUSP) activation by its C-terminal ubiquitin-like domain (HUBL) and allosteric regulation by GMP-synthetase.
分子名称: CHLORIDE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7
著者Faesen, A.C, Perrakis, A, Sixma, T.K.
登録日2011-06-03
公開日2011-10-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mechanism of Usp7/Hausp Activation by its C- Terminal Ubiquitin-Like Domain and Allosteric Regulation by Gmp-Synthetase
Mol.Cell, 44, 2011
1I2T
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X-RAY STRUCTURE OF THE HUMAN HYPERPLASTIC DISCS PROTEIN: AN ORTHOLOG OF THE C-TERMINAL DOMAIN OF POLY(A)-BINDING PROTEIN
分子名称: HYD PROTEIN
著者Deo, R.C, Sonenberg, N, Burley, S.K.
登録日2001-02-12
公開日2001-04-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献X-ray structure of the human hyperplastic discs protein: an ortholog of the C-terminal domain of poly(A)-binding protein.
Proc.Natl.Acad.Sci.USA, 98, 2001
2LWX
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Solution structure of the C-terminal Pdr1-activating domain of the J-protein Zuo1
分子名称: Zuotin
著者Volkman, B.F, Ducett, J.K, Peterson, F.C, Craig, E.A.
登録日2012-08-08
公開日2012-10-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Unfolding of the C-terminal domain of the j-protein zuo1 releases autoinhibition and activates pdr1-dependent transcription.
J.Mol.Biol., 425, 2013
2J8P
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NMR structure of C-terminal domain of human CstF-64
分子名称: CLEAVAGE STIMULATION FACTOR 64 KDA SUBUNIT
著者Qu, X, Perez-Canadillas, J.M, Agrawal, S, De Baecke, J, Cheng, H, Varani, G, Moore, C.
登録日2006-10-27
公開日2006-11-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The C-Terminal Domains of Vertebrate Cstf-64 and its Yeast Orthologue RNA15 Form a New Structure Critical for Mrna 3'-End Processing.
J.Biol.Chem., 282, 2007
2M45
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NMR solution structure of the C-terminus of the minichromosome maintenance protein MCM from Sulfolobus solfataricus
分子名称: Minichromosome maintenance protein MCM
著者Wiedemann, C, Ohlenschlager, O, Medagli, B, Onesti, S, Gorlach, M.
登録日2013-01-29
公開日2014-01-29
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure and regulatory role of the C-terminal winged helix domain of the archaeal minichromosome maintenance complex
Nucleic Acids Res., 43, 2015
161D
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A SINGLE 2'-HYDROXYL GROUP CONVERTS B-DNA TO A-DNA: CRYSTAL STRUCTURE OF THE DNA-RNA CHIMERIC DECAMER DUPLEX D(CCGGC)R(G)D(CCGG) WITH A NOVEL INTERMOLECULAR G.C BASE-PAIRED QUADRUPLET
分子名称: DNA/RNA (5'-D(*CP*CP*GP*GP*CP*)-R(*GP*)-D(*CP*CP*GP*G)-3')
著者Ban, C, Ramakrishnan, B, Sundaralingam, M.
登録日1994-02-10
公開日1994-05-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A single 2'-hydroxyl group converts B-DNA to A-DNA. Crystal structure of the DNA-RNA chimeric decamer duplex d(CCGGC)r(G)d(CCGG) with a novel intermolecular G-C base-paired quadruplet.
J.Mol.Biol., 236, 1994
1C7M
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SOLUTION STRUCTURE OF THE FUNCTIONAL DOMAIN OF PARACOCCUS DENITRIFICANS CYTOCHROME C552 IN THE REDUCED STATE
分子名称: HEME C, PROTEIN (CYTOCHROME C552)
著者Pristovsek, P, Luecke, C, Reincke, B, Ludwig, B, Rueterjans, H.
登録日2000-03-03
公開日2000-07-19
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the functional domain of Paracoccus denitrificans cytochrome c552 in the reduced state.
Eur.J.Biochem., 267, 2000
1S62
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Solution structure of the Escherichia coli TolA C-terminal domain
分子名称: TolA protein
著者Deprez, C, Blanchard, L, Simorre, J.-P, Gavioli, M, Guerlesquin, F, Lazdunski, C, Lloubes, R, Marion, D.
登録日2004-01-22
公開日2005-02-15
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of the E.coli TolA C-terminal domain reveals conformational changes upon binding to the phage g3p N-terminal domain.
J.Mol.Biol., 346, 2005
3R98
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BU of 3r98 by Molmil
Joint Neutron and X-ray structure of Cytochrome c peroxidase
分子名称: Cytochrome c peroxidase, PROTOPORPHYRIN IX CONTAINING FE
著者Blakeley, M.P, Fisher, S.J, Gumiero, A, Moody, P.C.E, Raven, E.L.
登録日2011-03-25
公開日2012-04-04
最終更新日2024-03-20
実験手法NEUTRON DIFFRACTION (2.4 Å), X-RAY DIFFRACTION
主引用文献Hydrogen bonds in heme peroxidases: a combined X-ray and neutron study of cytochrome c peroxidase
To be Published
1URF
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BU of 1urf by Molmil
HR1b domain from PRK1
分子名称: PROTEIN KINASE C-LIKE 1
著者Owen, D, Lowe, P.N, Nietlispach, D, Brosnan, C.E, Chirgadze, D.Y, Parker, P.J, Blundell, T.L, Mott, H.R.
登録日2003-10-29
公開日2003-11-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Molecular Dissection of the Interaction between the Small G Proteins Rac1 and Rhoa and Protein Kinase C-Related Kinase 1 (Prk1)
J.Biol.Chem., 278, 2003
1CX1
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SECOND N-TERMINAL CELLULOSE-BINDING DOMAIN FROM CELLULOMONAS FIMI BETA-1,4-GLUCANASE C, NMR, 22 STRUCTURES
分子名称: ENDOGLUCANASE C
著者Brun, E, Johnson, P.E, Creagh, L.A, Haynes, C.A, Tomme, P, Webster, P, Kilburn, D.G, McIntosh, L.P.
登録日1999-08-27
公開日2000-04-02
最終更新日2017-02-01
実験手法SOLUTION NMR
主引用文献Structure and binding specificity of the second N-terminal cellulose-binding domain from Cellulomonas fimi endoglucanase C.
Biochemistry, 39, 2000
1COK
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STRUCTURE OF THE C-TERMINAL DOMAIN OF P73
分子名称: PROTEIN (SECOND SPLICE VARIANT P73)
著者Chi, S.-W, Ayed, A, Arrowsmith, C.H.
登録日1999-05-28
公開日1999-08-17
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of a conserved C-terminal domain of p73 with structural homology to the SAM domain.
EMBO J., 18, 1999
3QGE
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Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase complex with (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid and (2R)-4-(2,6-dimethoxypyrimidin-4-yl)-N-(4-methoxybenzyl)-1-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazine-2-carboxamide
分子名称: (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid, (2R)-4-(2,6-dimethoxypyrimidin-4-yl)-N-(4-methoxybenzyl)-1-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazine-2-carboxamide, RNA-directed RNA polymerase, ...
著者Sheriff, S.
登録日2011-01-24
公開日2011-04-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase.
Bioorg.Med.Chem.Lett., 21, 2011
3QGD
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Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase complex with (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid and (2R)-4-(2,6-dimethoxypyrimidin-4-yl)-1-[(4-ethylphenyl)sulfonyl]-N-(4-methoxybenzyl)piperazine-2-carboxamide
分子名称: (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid, (2R)-4-(2,6-dimethoxypyrimidin-4-yl)-1-[(4-ethylphenyl)sulfonyl]-N-(4-methoxybenzyl)piperazine-2-carboxamide, RNA-directed RNA polymerase, ...
著者Sheriff, S.
登録日2011-01-24
公開日2011-04-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase.
Bioorg.Med.Chem.Lett., 21, 2011
3R99
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Joint Neutron and X-ray structure of Cytochrome c peroxidase
分子名称: Cytochrome c peroxidase, PROTOPORPHYRIN IX CONTAINING FE
著者Blakeley, M.P, Fisher, S.J, Gumiero, A, Moody, P.C.E, Raven, E.L.
登録日2011-03-25
公開日2012-04-04
最終更新日2024-03-20
実験手法NEUTRON DIFFRACTION (2.4 Å), X-RAY DIFFRACTION
主引用文献Hydrogen bonds in heme peroxidases: a combined X-ray and neutron study of cytochrome c peroxidase
To be Published
1XZO
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Identification of a disulfide switch in BsSco, a member of the Sco family of cytochrome c oxidase assembly proteins
分子名称: CADMIUM ION, CALCIUM ION, Hypothetical protein ypmQ
著者Ye, Q, Imriskova-Sosova, I, Hill, B.C, Jia, Z, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2004-11-12
公開日2005-03-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Identification of a Disulfide Switch in BsSco, a Member of the Sco Family of Cytochrome c Oxidase Assembly Proteins
Biochemistry, 44, 2005
2PX7
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Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8
分子名称: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
著者Chen, L, Tsukuda, M, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Chen, L.-Q, Liu, Z.-J, Lee, D, Chang, S.-H, Nguyen, D, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-05-14
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8.
To be Published

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