3CZD
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![BU of 3czd by Molmil](/molmil-images/mine/3czd) | Crystal structure of human glutaminase in complex with L-glutamate | 分子名称: | GLUTAMIC ACID, GLYCEROL, Glutaminase kidney isoform, ... | 著者 | Karlberg, T, Welin, M, Andersson, J, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wikstrom, M, Schuler, H, Structural Genomics Consortium (SGC) | 登録日 | 2008-04-29 | 公開日 | 2008-07-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism. Proc.Natl.Acad.Sci.USA, 109, 2012
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6QKZ
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![BU of 6qkz by Molmil](/molmil-images/mine/6qkz) | Full length GluA1/2-gamma8 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, ... | 著者 | Herguedas, B, Garcia-Nafria, J, Greger, I.G. | 登録日 | 2019-01-30 | 公開日 | 2019-03-27 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | 主引用文献 | Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP gamma 8. Science, 364, 2019
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7P5O
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7PGU
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![BU of 7pgu by Molmil](/molmil-images/mine/7pgu) | Autoinhibited structure of human neurofibromin isoform 2 stabilized by Zinc. | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Neurofibromin, ZINC ION | 著者 | Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. | 登録日 | 2021-08-15 | 公開日 | 2021-11-17 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | The structure of neurofibromin isoform 2 reveals different functional states. Nature, 599, 2021
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7PGT
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![BU of 7pgt by Molmil](/molmil-images/mine/7pgt) | The structure of human neurofibromin isoform 2 in opened conformation. | 分子名称: | Neurofibromin, ZINC ION | 著者 | Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. | 登録日 | 2021-08-15 | 公開日 | 2021-11-17 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | The structure of neurofibromin isoform 2 reveals different functional states. Nature, 599, 2021
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7PGS
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![BU of 7pgs by Molmil](/molmil-images/mine/7pgs) | Consensus structure of human Neurofibromin isoform 2 | 分子名称: | Neurofibromin, ZINC ION | 著者 | Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. | 登録日 | 2021-08-15 | 公開日 | 2021-11-17 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | The structure of neurofibromin isoform 2 reveals different functional states. Nature, 599, 2021
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7PGR
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![BU of 7pgr by Molmil](/molmil-images/mine/7pgr) | The structure of human neurofibromin isoform 2 in closed conformation | 分子名称: | Neurofibromin, ZINC ION | 著者 | Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. | 登録日 | 2021-08-15 | 公開日 | 2021-11-17 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | The structure of neurofibromin isoform 2 reveals different functional states. Nature, 599, 2021
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2MX7
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7P3U
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![BU of 7p3u by Molmil](/molmil-images/mine/7p3u) | Chitin-active fungal AA11 LPMO | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Endoglucanase, putative | 著者 | Rohr, A.K, Stoepamo, F.G, Eijsink, V.G.H. | 登録日 | 2021-07-08 | 公開日 | 2022-07-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Characterization of a lytic polysaccharide monooxygenase from Aspergillus fumigatus shows functional variation among family AA11 fungal LPMOs. J.Biol.Chem., 297, 2021
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2Y8V
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![BU of 2y8v by Molmil](/molmil-images/mine/2y8v) | Structure of chitinase, ChiC, from Aspergillus fumigatus. | 分子名称: | CLASS III CHITINASE, PUTATIVE, SODIUM ION | 著者 | Rush, C.L, Schuettelkopf, A.W, Gay, L.M, van Aalten, D.M.F. | 登録日 | 2011-02-10 | 公開日 | 2012-02-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structure of Chitinase, Chic, from Aspergillus Fumigatus. To be Published
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2NNT
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![BU of 2nnt by Molmil](/molmil-images/mine/2nnt) | General structural motifs of amyloid protofilaments | 分子名称: | Transcription elongation regulator 1 | 著者 | Ferguson, N, Becker, J, Tidow, H, Tremmel, S, Sharpe, T.D, Krause, G, Flinders, J, Petrovich, M, Berriman, J, Oschkinat, H, Fersht, A.R. | 登録日 | 2006-10-24 | 公開日 | 2006-11-14 | 最終更新日 | 2023-12-27 | 実験手法 | SOLID-STATE NMR | 主引用文献 | General structural motifs of amyloid protofilaments. Proc.Natl.Acad.Sci.Usa, 103, 2006
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3FE2
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![BU of 3fe2 by Molmil](/molmil-images/mine/3fe2) | Human DEAD-BOX RNA helicase DDX5 (P68), conserved domain I in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Probable ATP-dependent RNA helicase DDX5, ... | 著者 | Karlberg, T, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wikstrom, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) | 登録日 | 2008-11-27 | 公開日 | 2008-12-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Comparative Structural Analysis of Human DEAD-Box RNA Helicases Plos One, 5, 2010
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7BKY
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![BU of 7bky by Molmil](/molmil-images/mine/7bky) | Endothiapepsin structure obtained at 298K with fragment BTB09871 bound from a dataset collected with JUNGFRAU detector | 分子名称: | DIMETHYL SULFOXIDE, Endothiapepsin, PENTAETHYLENE GLYCOL, ... | 著者 | Engilberge, S, Huang, C.-Y, Leonarski, F, Wojdyla, J.A, Marsh, M, Olieric, V, Wang, M. | 登録日 | 2021-01-17 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Endothiapepsin structure obtained at 298K with fragment BTB09871 bound from a dataset collected with JUNGFRAU detector To Be Published
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7BKR
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![BU of 7bkr by Molmil](/molmil-images/mine/7bkr) | Endothiapepsin structure obtained at 298K and 40 mM DMSO from a dataset collected with JUNGFRAU detector | 分子名称: | DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, Endothiapepsin, ... | 著者 | Engilberge, S, Huang, C.-Y, Leonarski, F, Wojdyla, J.A, Marsh, M, Olieric, V, Wang, M. | 登録日 | 2021-01-17 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Endothiapepsin structure obtained at 298K and 40 mM DMSO from a dataset collected with JUNGFRAU detector To Be Published
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7BKV
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![BU of 7bkv by Molmil](/molmil-images/mine/7bkv) | Endothiapepsin structure obtained at 100K with fragment AC39729 bound | 分子名称: | 5-fluoranylpyridin-2-amine, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | 著者 | Engilberge, S, Huang, C.-Y, Smith, K.M.L, Eris, D, Marsh, M, Wang, M, Wojdyla, J.A. | 登録日 | 2021-01-17 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Endothiapepsin structure obtained at 100K with fragment AC39729 bound To Be Published
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7BKS
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![BU of 7bks by Molmil](/molmil-images/mine/7bks) | 100K endothiapepsin structure obtained in presence of 40 mM DMSO | 分子名称: | DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, Endothiapepsin, ... | 著者 | Engilberge, S, Huang, C.-Y, Smith, K.M.L, Eris, D, Marsh, M, Wang, M, Wojdyla, J.A. | 登録日 | 2021-01-17 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | 100K endothiapepsin structure obtained in presence of 40 mM DMSO To Be Published
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7BKU
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![BU of 7bku by Molmil](/molmil-images/mine/7bku) | Endothiapepsin structure obtained at 100K with fragment JFD03909 bound | 分子名称: | 1,10-PHENANTHROLINE, DIMETHYL SULFOXIDE, Endothiapepsin | 著者 | Engilberge, S, Huang, C.-Y, Smith, K.M.L, Eris, D, Marsh, M, Wang, M, Wojdyla, J.A. | 登録日 | 2021-01-17 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Endothiapepsin structure obtained at 100K with fragment JFD03909 bound To Be Published
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7BKZ
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![BU of 7bkz by Molmil](/molmil-images/mine/7bkz) | Endothiapepsin structure obtained at 298K after a soaking with fragment AC39729 from a dataset collected with JUNGFRAU detector | 分子名称: | DIMETHYL SULFOXIDE, Endothiapepsin | 著者 | Engilberge, S, Huang, C.-Y, Leonarski, F, Wojdyla, J.A, Marsh, M, Olieric, V, Wang, M. | 登録日 | 2021-01-17 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Endothiapepsin structure obtained at 298K after a soaking with fragment AC39729 from a dataset collected with JUNGFRAU detector To Be Published
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4TX6
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![BU of 4tx6 by Molmil](/molmil-images/mine/4tx6) | AfChiA1 in complex with compound 1 | 分子名称: | 3-(2-methoxyphenyl)-6-methyl[1,2]oxazolo[5,4-d]pyrimidin-4(5H)-one, Class III chitinase ChiA1, PHOSPHATE ION | 著者 | van Aalten, D.M.F. | 登録日 | 2014-07-02 | 公開日 | 2014-08-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Screening-based discovery of Aspergillus fumigatus plant-type chitinase inhibitors FEBS Lett, 588, 2014
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1OMQ
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1EAK
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![BU of 1eak by Molmil](/molmil-images/mine/1eak) | Catalytic domain of proMMP-2 E404Q mutant | 分子名称: | 72 KDA TYPE IV COLLAGENASE, CALCIUM ION, INHIBITOR PEPTIDE, ... | 著者 | Bergmann, U, Tuuttila, A, Tryggvason, K, Morgunova, E. | 登録日 | 2001-07-12 | 公開日 | 2002-08-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Crystal Structure of Human Mmp-2 Reveals a New P To be Published
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6SLD
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![BU of 6sld by Molmil](/molmil-images/mine/6sld) | Structure of the Phosphatidylcholine Binding Mutant of Yeast Sec14 Homolog Sfh1 (S175I,T177I) in Complex with Phosphatidylinositol | 分子名称: | (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CRAL-TRIO domain-containing protein YKL091C | 著者 | Berger, J, Fitz, M, Johnen, P, Shanmugaratnam, S, Hocker, B, Stiel, A.C, Schaaf, G. | 登録日 | 2019-08-19 | 公開日 | 2020-08-19 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure of the Phosphatidylcholine Binding Mutant of Yeast Sec14 Homolog Sfh1 (S175I,T177I) in Complex with Phosphatidylinositol To Be Published
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5KJM
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![BU of 5kjm by Molmil](/molmil-images/mine/5kjm) | SMYD2 in complex with AZ931 | 分子名称: | 6-[2-[4-[2-(3,4-dichlorophenyl)ethyl]piperazin-1-yl]phenyl]-~{N}-(3-pyrrolidin-1-ylpropyl)-2~{H}-pyrazolo[3,4-b]pyridine-4-carboxamide, N-lysine methyltransferase SMYD2, S-ADENOSYLMETHIONINE, ... | 著者 | Ferguson, A. | 登録日 | 2016-06-20 | 公開日 | 2016-12-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Design, Synthesis, and Biological Activity of Substrate Competitive SMYD2 Inhibitors. J. Med. Chem., 59, 2016
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4K8Z
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![BU of 4k8z by Molmil](/molmil-images/mine/4k8z) | KOD Polymerase in binary complex with dsDNA | 分子名称: | 1,2-ETHANEDIOL, COBALT HEXAMMINE(III), DNA (5'-D(*AP*AP*AP*TP*TP*CP*GP*CP*AP*GP*TP*TP*CP*GP*CP*G)-3'), ... | 著者 | Bergen, K, Betz, K, Welte, W, Diederichs, K, Marx, A. | 登録日 | 2013-04-19 | 公開日 | 2013-06-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structures of KOD and 9N DNA Polymerases Complexed with Primer Template Duplex Chembiochem, 14, 2013
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6DD8
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![BU of 6dd8 by Molmil](/molmil-images/mine/6dd8) | Structure of mouse SYCP3, P21 form | 分子名称: | Synaptonemal complex protein 3 | 著者 | Rosenberg, S.C, Munoz, I.C, Uson, I, Corbett, K.D. | 登録日 | 2018-05-09 | 公開日 | 2018-08-01 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A conserved filamentous assembly underlies the structure of the meiotic chromosome axis. Elife, 8, 2019
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