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PDB: 351 件

2C56
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A comparative study of uracil DNA glycosylases from human and herpes simplex virus type 1
分子名称: URACIL DNA GLYCOSYLASE, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
著者Krusong, K, Carpenter, E.P, Bellamy, S.R.W, Savva, R, Baldwin, G.S.
登録日2005-10-26
公開日2005-11-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Comparative Study of Uracil-DNA Glycosylases from Human and Herpes Simplex Virus Type 1.
J.Biol.Chem., 281, 2006
2DVC
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Structure of the bovine lactoferrin C-lobe complex with sucrose at 3.0 A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
著者Mir, R, Prem Kumar, R, Bhardwaj, R, Ethayathulla, A.S, Sinha, M, Singh, N, Bhushan, A, Sharma, S, Kaur, P, Singh, T.P.
登録日2006-07-31
公開日2006-08-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the bovine lactoferrin C-lobe complex with sucrose at 3.0 A resolution
To be Published
2GDU
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E232Q mutant of sucrose phosphorylase from BIFIDOBACTERIUM ADOLESCENTIS in complex with sucrose
分子名称: beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, sucrose phosphorylase
著者Skov, L.K, Mirza, O, Gajhede, M, Kastrup, J.S.
登録日2006-03-17
公開日2006-09-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Rearrangements of Sucrose Phosphorylase from Bifidobacterium adolescentis during Sucrose Conversion
J.Biol.Chem., 281, 2006
2GUP
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Structural Genomics, the crystal structure of a ROK family protein from Streptococcus pneumoniae TIGR4 in complex with sucrose
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ROK family protein, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
著者Tan, K, Li, H, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2006-05-01
公開日2006-05-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献The crystal structure of a ROK family protein from Streptococcus pneumoniae TIGR4 in complex with sucrose
To be Published
2H6F
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Protein Farnesyltransferase Complexed with a Farnesylated DDPTASACVLS Peptide Product at 1.5A Resolution
分子名称: ACETIC ACID, FARNESYL, Protein farnesyltransferase beta subunit, ...
著者Terry, K.L, Beese, L.S.
登録日2006-05-31
公開日2006-08-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
Biochemistry, 45, 2006
2H6G
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W102T Protein Farnesyltransferase Mutant Complexed with a Geranylgeranylated DDPTASACVLS Peptide Product at 1.85A Resolution
分子名称: GERAN-8-YL GERAN, Protein farnesyltransferase beta subunit, Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, ...
著者Terry, K.L, Beese, L.S.
登録日2006-05-31
公開日2006-08-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
Biochemistry, 45, 2006
2H6H
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Y365F Protein Farnesyltransferase Mutant Complexed with a Farnesylated DDPTASACVLS Peptide Product at 1.8A
分子名称: ACETIC ACID, FARNESYL, Protein farnesyltransferase beta subunit, ...
著者Terry, K.L, Beese, L.S.
登録日2006-05-31
公開日2006-08-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
Biochemistry, 45, 2006
2H6I
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W102T/Y365F Protein Farnesyltransferase Double Mutant Complexed with a Geranylgeranylated DDPTASACVLS Peptide Product at 3.0A
分子名称: GERAN-8-YL GERAN, Protein farnesyltransferase beta subunit, Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, ...
著者Terry, K.L, Beese, L.S.
登録日2006-05-31
公開日2006-08-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
Biochemistry, 45, 2006
2HDS
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AmpC beta-lactamase in complex with 4-Methanesulfonylamino benzoic acid
分子名称: 4-[(METHYLSULFONYL)AMINO]BENZOIC ACID, Beta-lactamase, PHOSPHATE ION, ...
著者Babaoglu, K, Shoichet, B.K.
登録日2006-06-20
公開日2006-11-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Deconstructing fragment-based inhibitor discovery
Nat.Chem.Biol., 2, 2006
2HHQ
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O6-methyl-guanine:T pair in the polymerase-10 basepair position
分子名称: 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*GP*CP*CP*TP*GP*AP*CP*TP*CP*GP*TP*AP*TP*GP*A)-3', DNA polymerase I, ...
著者Warren, J.J, Forsberg, L.J, Beese, L.S.
登録日2006-06-28
公開日2006-12-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHS
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O6-methyl:C pair in the polymerase-10 basepair position
分子名称: 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*GP*CP*AP*TP*GP*A)-3', DNA polymerase I, ...
著者Warren, J.J, Forsberg, L.J, Beese, L.S.
登録日2006-06-28
公開日2006-12-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHT
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C:O6-methyl-guanine pair in the polymerase-2 basepair position
分子名称: 5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*TP*CP*G)-3', 5'-D(*GP*TP*AP*CP*(6OG)P*AP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', DNA polymerase I, ...
著者Warren, J.J, Forsberg, L.J, Beese, L.S.
登録日2006-06-28
公開日2006-12-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHU
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C:O6-methyl-guanine in the polymerase postinsertion site (-1 basepair position)
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*CP*C)-3', 5'-D(*GP*TP*AP*CP*(6OG)P*GP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', ...
著者Warren, J.J, Forsberg, L.J, Beese, L.S.
登録日2006-06-28
公開日2006-12-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHV
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T:O6-methyl-guanine in the polymerase-2 basepair position
分子名称: 5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*TP*TP*G)-3', 5'-D(*GP*TP*AP*CP*(6OG)P*AP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', DNA Polymerase I, ...
著者Warren, J.J, Forsberg, L.J, Beese, L.S.
登録日2006-06-28
公開日2006-12-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHW
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ddTTP:O6-methyl-guanine pair in the polymerase active site, in the closed conformation
分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3', ...
著者Warren, J.J, Forsberg, L.J, Beese, L.S.
登録日2006-06-28
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHX
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O6-methyl-guanine in the polymerase template preinsertion site
分子名称: 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*G)-3', DNA Polymerase I, ...
著者Warren, J.J, Forsberg, L.J, Beese, L.S.
登録日2006-06-28
公開日2006-12-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HRQ
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Crystal structure of Human Liver Carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Soman (GD)
分子名称: (1R)-1,2,2-TRIMETHYLPROPYL (R)-METHYLPHOSPHINATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Liver carboxylesterase 1, ...
著者Fleming, C.D, Redinbo, M.R.
登録日2006-07-20
公開日2007-05-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun.
Biochemistry, 46, 2007
2HRR
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Crystal structure of Human Liver Carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Tabun (GA)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Liver carboxylesterase 1, N-acetyl-alpha-neuraminic acid, ...
著者Fleming, C.D, Redinbo, M.R.
登録日2006-07-20
公開日2007-05-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun.
Biochemistry, 46, 2007
2HVH
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ddCTP:O6MeG pair in the polymerase active site (0 position)
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*CP*A*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3', ...
著者Warren, J.J, Forsberg, L.J, Beese, L.S.
登録日2006-07-28
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.492 Å)
主引用文献The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HVI
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ddCTP:G pair in the polymerase active site (0 position)
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*C*AP*TP*GP*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3', ...
著者Warren, J.J, Forsberg, L.J, Beese, L.S.
登録日2006-07-28
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HW3
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T:O6-methyl-guanine pair in the polymerase postinsertion site (-1 basepair position)
分子名称: 5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*TP*T)-3', 5'-D(*GP*TP*A*CP*(6OG)P*AP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', DNA Polymerase I, ...
著者Warren, J.J, Forsberg, L.J, Beese, L.S.
登録日2006-07-31
公開日2006-12-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2I5J
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Crystal structure of HIV-1 reverse transcriptase (RT) in complex with DHBNH, an RNASE H inhibitor
分子名称: (E)-3,4-DIHYDROXY-N'-[(2-METHOXYNAPHTHALEN-1-YL)METHYLENE]BENZOHYDRAZIDE, MAGNESIUM ION, Reverse transcriptase/ribonuclease H P51 subunit, ...
著者Himmel, D.M, Sarafianos, S.G, Knight, J.L, Levy, R.M, Arnold, E.
登録日2006-08-24
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献HIV-1 reverse transcriptase structure with RNase H inhibitor dihydroxy benzoyl naphthyl hydrazone bound at a novel site.
Acs Chem.Biol., 1, 2006
2IEJ
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Human Protein Farnesyltransferase Complexed with Inhibitor Compound STN-48 And FPP Analog at 1.8A Resolution
分子名称: ACETATE ION, METHYL N-{(3S)-1-[(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-6-PHENYL-1,2,3,4-TETRAHYDROQUINOLIN-3-YL}-N-[(1-METHYL-1H-IMIDAZOL-4-YL)SULFONYL]GLYCINATE, Protein farnesyltransferase subunit beta, ...
著者Hast, M.A, Beese, L.S.
登録日2006-09-19
公開日2007-01-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase.
Mol.Biochem.Parasitol., 152, 2007
2NXZ
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HIV-1 gp120 Envelope Glycoprotein (T257S, S334A, S375W) Complexed with CD4 and Antibody 17b
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, ...
著者Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D.
登録日2006-11-20
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY1
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HIV-1 gp120 Envelope Glycoprotein (I109C, T257S, S334A, S375W, Q428C) Complexed with CD4 and Antibody 17b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ...
著者Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D.
登録日2006-11-20
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007

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