PDB: 153 件ウェブページステータス検索Chemie searchBIRD

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6AHO	Crystal structure of Kap114p 分子名称: Importin subunit beta-5 著者 Liao, C.C, Shankar, S, Ahmed, G.R, Hsia, K.C. 登録日 2018-08-20 公開日 2019-10-23 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Karyopherin Kap114p-mediated trans-repression controls ribosomal gene expression under saline stress. Embo Rep., 21, 2020
6A3B	MVM NES mutant Nm13 in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... 著者 Sun, Q, Li, Y. 登録日 2018-06-15 公開日 2019-06-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
6KFT	MVM NS2 mutant Nm42 in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... 著者 Sun, Q, Li, Y. 登録日 2019-07-08 公開日 2020-07-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
5DH9	Crystal Structure of PKI NES Flip Mutant Peptide in complex with CRM1-Ran-RanBP1 分子名称: Engineered Nuclear Export Signal Peptide (PKINES-Flip3 mutant), Exportin-1, GLYCEROL, ... 著者 Fung, H.Y, Chook, Y.M. 登録日 2015-08-30 公開日 2015-09-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural determinants of nuclear export signal orientation in binding to exportin CRM1. Elife, 4, 2015
6X2O	Crystal Structure of unliganded CRM1(E571K)-Ran-RanBP1 分子名称: Exportin-1, GTP-binding nuclear protein Ran, MAGNESIUM ION, ... 著者 Baumhardt, J.M. 登録日 2020-05-20 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.551 Å) 主引用文献 Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
7B51	Crystal structure of human CRM1 covalently modified by 2-mercaptoethanol at Cys528 分子名称: BETA-MERCAPTOETHANOL, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Shaikhqasem, A, Ficner, R. 登録日 2020-12-03 公開日 2021-03-10 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Crystal structure of human CRM1, covalently modified by 2-mercaptoethanol on Cys528, in complex with RanGTP. Acta Crystallogr.,Sect.F, 77, 2021
2Z5K	Complex of Transportin 1 with TAP NLS 分子名称: Nuclear RNA export factor 1, PHOSPHATE ION, Transportin-1 著者 Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Kose, S, Imamoto, N, Sato, M. 登録日 2007-07-14 公開日 2007-10-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
1GCJ	N-TERMINAL FRAGMENT OF IMPORTIN-BETA 分子名称: IMPORTIN BETA 著者 Lee, S.J, Imamoto, N, Sakai, H, Nakagawa, A, Kose, S, Koike, M, Yamamoto, M, Kumasaka, T, Yoneda, Y, Tsukihara, T. 登録日 2000-07-31 公開日 2000-10-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The adoption of a twisted structure of importin-beta is essential for the protein-protein interaction required for nuclear transport. J.Mol.Biol., 302, 2000
5ZPU	LFS829 in complex with CRM1-Ran-RanBP1 分子名称: (Z)-{[(3E)-4-{(R)-[3,5-bis(trifluoromethyl)phenyl]sulfinyl}but-3-en-1-yl]imino}methanethiol, CHLORIDE ION, Exportin-1,Exportin-1, ... 著者 Sun, Q, Lei, Y. 登録日 2018-04-16 公開日 2019-04-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 To be published To Be Published
3W5K	Crystal structure of Snail1 and importin beta complex 分子名称: Importin subunit beta-1, ZINC ION, Zinc finger protein SNAI1 著者 Choi, S, Yamashita, E, Yasuhara, N, Song, J, Son, S.Y, Won, Y.H, Shin, Y.S, Sekimoto, T, Park, I.Y, Yoneda, Y, Lee, S.J. 登録日 2013-01-30 公開日 2014-03-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for the selective nuclear import of the C2H2 zinc-finger protein Snail by importin beta. Acta Crystallogr.,Sect.D, 70, 2014
6A38	MVM NS2 NES in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... 著者 Sun, Q, Li, Y. 登録日 2018-06-15 公開日 2019-06-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
4OO6	Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1) 分子名称: RNA-binding protein 39, Transportin-1 著者 Sampathkumar, P, Brower, A, Soniat, M, Bonanno, J, Hillerich, B, Seidel, R.D, Rout, M.P, Chook, Y.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals) 登録日 2014-01-30 公開日 2014-02-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1) to be published
2BKU	Kap95p:RanGTP complex 分子名称: GTP-BINDING NUCLEAR PROTEIN RAN, GUANOSINE-5'-TRIPHOSPHATE, IMPORTIN BETA-1 SUBUNIT, ... 著者 Lee, S.J, Matsuura, Y, Liu, S.M, Stewart, M. 登録日 2005-02-21 公開日 2005-05-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Basis for Nuclear Import Complex Dissociation by Rangtp Nature, 435, 2005
5VE8	Crystal structure of full-length Kluyveromyces lactis Kap123 with histone H3 1-28 分子名称: Histone H3, Kap123 著者 An, S, Yoon, J, Song, J.-J, Cho, U.-S. 登録日 2017-04-04 公開日 2017-11-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123. Elife, 6, 2017
6N1Z	Importin-9 bound to H2A-H2B 分子名称: Histone H2A, Histone H2B 1.1, Importin-9 著者 Tomchick, D.R, Chook, Y.M, Padavannil, A. 登録日 2018-11-12 公開日 2019-03-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone. Elife, 8, 2019
7CYL	Crystal structure of Karyopherin-beta2 in complex with FUS PY-NLS(P525L) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Chook, Y.M. 登録日 2020-09-03 公開日 2021-02-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanism of karyopherin-beta 2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X). Sci Rep, 11, 2021
6A3E	MVM NES mutant Nm15 in complex with CRM1-Ran-RanBP1 分子名称: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Sun, Q, Li, Y. 登録日 2018-06-15 公開日 2019-06-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
1O6P	Importin Beta bound to a GLFG Nucleoporin peptide 分子名称: IMPORTIN BETA-1 SUBUNIT, SYNTHETIC GLFG PEPTIDE 著者 Bayliss, R, Stewart, M. 登録日 2002-10-10 公開日 2003-04-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Glfg and Fxfg Nucleoporins Bind to Overlapping Sites on Importin-Beta J.Biol.Chem., 277, 2002
1F59	IMPORTIN-BETA-FXFG NUCLEOPORIN COMPLEX 分子名称: FXFG NUCLEOPORIN REPEATS, IMPORTIN BETA-1 著者 Bayliss, R, Littlewood, T, Stewart, M. 登録日 2000-06-13 公開日 2000-08-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking. Cell(Cambridge,Mass.), 102, 2000
1O6O	Importin Beta aa1-442 bound to five FxFG repeats from yeast Nsp1p. Second crystal form 分子名称: IMPORTIN BETA-1 SUBUNIT, NUCLEOPORIN NSP1 著者 Bayliss, R, Stewart, M. 登録日 2002-10-10 公開日 2003-10-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Glfg and Fxfg Nucleoporins Bind to Overlapping Sites on Importin-Beta J.Biol.Chem., 277, 2002
4HB3	Crystal structure of CRM1(T539S)-Ran-RanBP1 with weakly bound unmodeled Leptomycin B 分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
2XWU	CRYSTAL STRUCTURE OF IMPORTIN 13 - UBC9 COMPLEX 分子名称: IMPORTIN13, SUMO-CONJUGATING ENZYME UBC9 著者 Gruenwald, M, Bono, F. 登録日 2010-11-05 公開日 2010-12-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of Importin13-Ubc9 Complex: Nuclear Import and Release of a Key Regulator of Sumoylation. Embo J., 30, 2011
2X19	Crystal structure of Importin13 - RanGTP complex 分子名称: GTP-BINDING NUCLEAR PROTEIN GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, IMPORTIN-13, ... 著者 Bono, F, Cook, A.G, Gruenwald, M, Ebert, J, Conti, E. 登録日 2009-12-23 公開日 2010-02-16 最終更新日 2017-06-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Nuclear Import Mechanism of the Ejc Component Mago- Y14 Revealed by Structural Studies of Importin 13. Mol.Cell, 37, 2010
3NBZ	Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal I) 分子名称: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. 登録日 2010-06-04 公開日 2010-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nat.Struct.Mol.Biol., 17, 2010
6XJP	Crystal Structure of KPT-185 bound to CRM1 (537-DLTVK-541 to GLCEQ) 分子名称: Exportin-1, GTP-binding nuclear protein Ran, MAGNESIUM ION, ... 著者 Baumhardt, J.M, Chook, Y.M. 登録日 2020-06-24 公開日 2021-01-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.802 Å) 主引用文献 Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021

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